{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:07:09Z","timestamp":1789063629678,"version":"build-2803163510"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017963","name":"Education Department of Inner Mongolia Autonomous Region","doi-asserted-by":"publisher","award":["NJZY23128"],"award-info":[{"award-number":["NJZY23128"]}],"id":[{"id":"10.13039\/100017963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To systematically retrieve and summarize evidence on optimization strategies for caregiving behaviors of family caregivers of patients with enterostomy, and to provide an evidence\u2011based reference for clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is an evidence summary that adopts the rigorous methodological framework of systematic reviews. Evidence was searched from databases and websites including UpToDate, BMJ Best Practice, the International Guideline Network, the Agency for Healthcare Research and Quality (USA), the Registered Nurses\u2019 Association of Ontario (Canada), the World Council of Enterostomal Therapists, the Wound, Ostomy and Continence Nurses Society (USA), the Chinese Medical Journal Database, Cochrane Library, Embase, PubMed, and CINAHL. The evidence types included clinical decisions, guidelines, systematic reviews, evidence summaries, and expert consensuses. The search period covered from database inception to January 31, 2026. Literature quality assessment was independently performed by at least two researchers trained in systematic evidence\u2011based methods. Evidence extraction and synthesis were conducted on the literature that met quality criteria, in combination with professional opinions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 13 articles were included: 2 clinical decisions, 8 guidelines, 1 systematic review, and 2 expert consensuses. Sixteen pieces of evidence were summarized across four domains: structured empowerment of care knowledge and skills, support strategies for the care process, maintenance of caregivers\u2019 physical and mental health, and construction of a multi\u2011dimensional support system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The best evidence summarized in this study is scientifically sound and practical to a certain extent, providing a reliable basis for healthcare professionals to develop intervention plans and implement evidence\u2011based practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0356569","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:22:42Z","timestamp":1789060962000},"page":"e0356569","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimization strategies for care\u2011giving behaviors of family caregivers for patients with enterostomy: An evidence summary"],"prefix":"10.1371","volume":"21","author":[{"given":"Yujie","family":"Liu","sequence":"first","affiliation":[{"name":"Nursing School, Inner Mongolia Medical University","place":["Hohhot, Inner Mongolia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Nursing School, Inner Mongolia Medical University","place":["Hohhot, Inner Mongolia, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4400-1113","authenticated-orcid":true,"given":"Aiping","family":"Li","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Inner Mongolia Medical University","place":["Hohhot, Inner Mongolia, China"],"department":["Nursing Department"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangqin","family":"Yun","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Inner Mongolia Medical University","place":["Hohhot, Inner Mongolia, China"],"department":["Gastrointestinal Surgery Department"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyang","family":"Chen","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Inner Mongolia Medical University","place":["Hohhot, Inner Mongolia, China"],"department":["Gastrointestinal Surgery Department"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"issue":"23","key":"pone.0356569.ref001","first-page":"1413","article-title":"Comparison and predictive analysis of cancer incidence, mortality, and prevalence between China and the world: interpretation of GLOBOCAN 2022 data","volume":"31","author":"Y Teng","year":"2024","journal-title":"Chin J Cancer Prev Treat"},{"issue":"4","key":"pone.0356569.ref002","article-title":"Sociodemographic and clinical characteristics of people with ostomy and the adaptive domains of Roy\u2019s theory: a cross-sectional study","volume":"19","author":"SSDM Xavier","year":"2024","journal-title":"PLoS One"},{"issue":"08","key":"pone.0356569.ref003","first-page":"36","article-title":"Influence of family empowerment intervention on caregivers of patients with permanent enterostomy","volume":"38","author":"Y Yang","year":"2023","journal-title":"J Nurs Sci"},{"issue":"13","key":"pone.0356569.ref004","first-page":"126","article-title":"Research progress on influencing factors of quality of life of patients with colorectal cancer enterostomy","volume":"63","author":"Y Zou","year":"2025","journal-title":"China Modern Doctor"},{"key":"pone.0356569.ref005","first-page":"51","article-title":"Analysis of the research status of family caregivers in China","volume":"09","author":"LM Liu","year":"2007","journal-title":"Nurs J Chin People\u2019s Liber Army"},{"issue":"10","key":"pone.0356569.ref006","article-title":"Experience of providing care to a family member with Crohn\u2019s disease and a temporary stoma: a qualitative study","volume":"9","author":"S Liu","year":"2023","journal-title":"Heliyon"},{"issue":"3","key":"pone.0356569.ref007","first-page":"327","article-title":"Analysis of the current situation and influencing factors of the sense of benefit from illness among caregivers of patients with permanent enterostomy","volume":"21","author":"LM Huang","year":"2023","journal-title":"General Pract Nurs"},{"issue":"1","key":"pone.0356569.ref008","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1186\/s12876-025-03872-5","article-title":"Risk factors for unplanned 31-day readmission after surgery for colorectal cancer patients: a meta-analysis","volume":"25","author":"N Qu","year":"2025","journal-title":"BMC Gastroenterol"},{"issue":"21","key":"pone.0356569.ref009","first-page":"1991","article-title":"Composition of different types of evidence-based questions","volume":"32","author":"Z Zhu","year":"2017","journal-title":"J Nurses Train"},{"issue":"4","key":"pone.0356569.ref010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1136\/ebmed-2016-110447","article-title":"EBHC pyramid 5.0 for accessing preappraised evidence and guidance","volume":"21","author":"BS Alper","year":"2016","journal-title":"Evid Based Med"},{"issue":"13","key":"pone.0356569.ref011","first-page":"1345","article-title":"The development of the evidence pyramid: from the \u201c6S\u201d model to the \u201c5S\u201d mode","volume":"40","author":"WJ Xing","year":"2025","journal-title":"J Nurses Train"},{"issue":"18","key":"pone.0356569.ref012","doi-asserted-by":"crossref","DOI":"10.1503\/cmaj.090449","article-title":"AGREE \u2161: advancing guideline development, reporting and evaluation in health care","volume":"182","author":"MC Brouwers","year":"2010","journal-title":"CMAJ"},{"key":"pone.0356569.ref013","doi-asserted-by":"crossref","DOI":"10.46658\/JBIMES-24-01","author":"E Aromataris","year":"2024","journal-title":"JBI manual for evidence synthesis"},{"issue":"11","key":"pone.0356569.ref014","first-page":"964","article-title":"JBI evidence pre-grading and evidence recommendation level system (2014 Edition)","volume":"30","author":"CQ Wang","year":"2015","journal-title":"J Nurses Train"},{"key":"pone.0356569.ref015","author":"RG Landmann","year":"2024"},{"key":"pone.0356569.ref016","author":"TD Francone","year":"2024"},{"key":"pone.0356569.ref017","unstructured":"Registered Nurses\u2019 Association of Ontario. Supporting Adults Who Anticipate or Live with an Ostomy. Toronto (ON): Registered Nurses\u2019 Association of Ontario; 2019 [cited 2026 Jan 31]. Available from: https:\/\/rnao.ca\/bpg\/guidelines\/ostomy"},{"key":"pone.0356569.ref018","unstructured":"Registered Nurses\u2019 Association of Ontario. Caring for a Person with an Ostomy. Toronto (ON): Registered Nurses\u2019 Association of Ontario; 2023 [cited 2026 Jan 31]. Available from: https:\/\/rnao.ca\/bpg\/long-term-care-toolkit\/topics\/professional-guide-caring-for-a-person-with-an-ostomy"},{"key":"pone.0356569.ref019","unstructured":"Registered Nurses\u2019 Association of Ontario. People-Centred Care. Toronto (ON): Registered Nurses\u2019 Association of Ontario; 2025 [cited 2026 Jan 31]. Available from: https:\/\/rnao.ca\/bpg\/guidelines\/people-centred-care"},{"key":"pone.0356569.ref020","unstructured":"NICE. Supporting adult carers. London: NICE; 2020 [cited 2026 Jan 31]. Available from: https:\/\/www.nice.org.uk\/guidance\/ng150"},{"issue":"10","key":"pone.0356569.ref021","first-page":"937","article-title":"Nursing guidelines for adult intestinal stomas","volume":"56","author":"Chinese Medical Association","year":"2025","journal-title":"New Med"},{"issue":"10","key":"pone.0356569.ref022","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1097\/DCR.0000000000002498","article-title":"Prepared on behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons","volume":"65","author":"BR Davis","year":"2022","journal-title":"Dis Colon Rectum"},{"issue":"1","key":"pone.0356569.ref023","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/WON.0000000000000396","article-title":"WOCN Society Clinical Guideline: Management of the Adult Patient With a Fecal or Urinary Ostomy - An Executive Summary","volume":"45","author":"Wound, Ostomy and Continence Nurses Society","year":"2018","journal-title":"J Wound Ostomy Continence Nurs"},{"key":"pone.0356569.ref024","unstructured":"World Council of Enterostomal Therapists. WCET international ostomy guideline. 2021 [cited 2026 Jan 31]. Available from: https:\/\/wcet-online.store.myshopify.com\/products\/international-ostomy-guideline-downloadable"},{"issue":"4","key":"pone.0356569.ref025","doi-asserted-by":"crossref","first-page":"371","DOI":"10.4103\/ijnmr.ijnmr_266_22","article-title":"Nursing intervention for quality of life in patients with ostomy: a systematic review","volume":"28","author":"A Heydari","year":"2023","journal-title":"Iran J Nurs Midwifery Res"},{"issue":"06","key":"pone.0356569.ref026","first-page":"599","article-title":"Expert consensus on the whole-course nutritional management of patients with colorectal cancer colostomy (2025 edition)","volume":"28","author":"Specialized Committee of Tumor Nutrition Chinese Anti-Cancer Association","year":"2025","journal-title":"Chin J Gastrointestinal Surg"},{"issue":"3","key":"pone.0356569.ref027","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/WON.0000000000000758","article-title":"Peristomal skin health: a WOCN Society consensus conference","volume":"48","author":"CR Ratliff","year":"2021","journal-title":"J Wound Ostomy Continence Nurs"},{"key":"pone.0356569.ref028","doi-asserted-by":"crossref","first-page":"2880","DOI":"10.1111\/jocn.14876","article-title":"Relationship between psychosocial adaptation and health-related quality of life of patients with stoma: A descriptive, cross-sectional study","volume":"28","author":"Y Zhang","year":"2019","journal-title":"J Clin Nurs"},{"key":"pone.0356569.ref029","article-title":"Applied research on quality-sensitive indicators for enterostomy care","author":"SY Zhao","year":"2025","journal-title":"J Nurses Train"},{"issue":"7","key":"pone.0356569.ref030","first-page":"551","article-title":"Research progress on the cultivation of specialized nurses in wound, stoma and incontinence","volume":"16","author":"RH Li","year":"2019","journal-title":"Chin J Nurs Educ"},{"issue":"2","key":"pone.0356569.ref031","doi-asserted-by":"crossref","first-page":"129","DOI":"10.11124\/JBISRIR-2017-003764","article-title":"Dietary management in people with an ileostomy: a scoping review protocol","volume":"17","author":"A Mitchell","year":"2019","journal-title":"JBI Database Syst Rev Implement Rep"},{"issue":"1","key":"pone.0356569.ref032","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/s41746-025-02131-x","article-title":"Caregiver perceptions of healthcare barriers across traditional and digital contexts: a mixed-methods analysis","volume":"8","author":"JB Duong","year":"2025","journal-title":"NPJ Digit Med"},{"issue":"22","key":"pone.0356569.ref033","doi-asserted-by":"crossref","DOI":"10.12968\/bjon.2020.29.22.S27","article-title":"Quality of life of family caregivers of patients with a stoma: a cross-sectional study from Iran","volume":"29","author":"H Rafiei","year":"2020","journal-title":"Br J Nurs"},{"issue":"03","key":"pone.0356569.ref034","first-page":"230","article-title":"Research progress on the burden of family caregivers of patients with intestinal stoma and nursing interventions","volume":"36","author":"CY Xie","year":"2021","journal-title":"J Nurses Train"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0356569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:22:50Z","timestamp":1789060970000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0356569"}},"subtitle":[],"editor":[{"given":"Zubing","family":"Mei","sequence":"first","affiliation":[{"name":"Shuguang Hospital","place":["CHINA"]}],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,9,10]]},"references-count":34,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0356569","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,10]]}}}