{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:09:57Z","timestamp":1790014197063,"version":"4.0.1"},"reference-count":55,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The variability of Lyme borreliosis (LB) clinical manifestations can complicate diagnosis and lead to prolonged periods of medical uncertainty. There is limited knowledge about how children experience and perceive LB. This study aimed to examine the perceptions, social representations, and experiences of LB among adolescents and their parents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Conducted from March to June 2023, this multicenter qualitative study used grounded theory and a dyadic approach with semi-structured interviews to identify themes and develop a theoretical model, adhering to COREQ guidelines. Adolescents and their parents were recruited from pediatric clinics, infectious disease pediatric consultations, and a pediatric pain center, ensuring diverse representations (age, gender, region, and serology results).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We interviewed 19 people. A total of 809 codes were identified and organized into three themes: (1) A personal experience of LB influenced by family history; (2) Ambivalence toward medical discourse; (3) A need for improved knowledge about LB to prevent misinformation. Adolescents expressed a range of emotions, including confusion about the nature of LB, disinterest in the disease itself, and a lack of clarity about their care pathways. They also expressed fear that LB, perceived as \u201cdormant,\u201d could resurface in the future and harm them.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>\n                      The study revealed contrasting experiences of LB between adolescents and their parents, with familial history and external influences shaping adolescents\u2019 and parents\u2019 perceptions, potentially fostering doubts, misunderstandings, and conflicts. Strengthening communication and the role of general practitioners in coordinating with specialized centers is crucial to streamline care pathways and reduce misinformation about LB.\n                      <jats:bold>Clinical trials registration number:<\/jats:bold>\n                      NCT05678478;\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT05678478?cond=Lyme%20Borreliosis&amp;term=adolescent&amp;rank=2\" xlink:type=\"simple\">https:\/\/clinicaltrials.gov\/study\/NCT05678478?cond=Lyme%20Borreliosis&amp;term=adolescent&amp;rank=2<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0357185","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:36:32Z","timestamp":1790012192000},"page":"e0357185","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perceptions, social representations, and experiences of suspected Lyme borreliosis among adolescents and their parents in France: A multicenter study"],"prefix":"10.1371","volume":"21","author":[{"given":"Sarah","family":"Covasso","sequence":"first","affiliation":[{"name":"Tick-Borne Diseases Reference Center, Paris and Northern Region, Intercommunal Hospital of Villeneuve Saint Georges","place":["Villeneuve-Saint-Georges, France"],"department":["Department of Infectious Diseases"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Paoletti","sequence":"additional","affiliation":[{"name":"Tick-Borne Diseases Reference Center, Paris and Northern Region, Intercommunal Hospital of Villeneuve Saint Georges","place":["Villeneuve-Saint-Georges, France"],"department":["Department of Infectious Diseases"]},{"name":"Tick-Borne Diseases Reference Center, Paris and Northern Region, Intercommunal Hospital of Villeneuve Saint Georges","place":["Villeneuve-Saint-Georges, France"],"department":["Department of Psychology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathie","family":"Lorrot","sequence":"additional","affiliation":[{"name":"University Hospital of Armand Trousseau","place":["Paris, France"],"department":["Department of Pediatrics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Dugu\u00e9","sequence":"additional","affiliation":[{"name":"University Hospital of Armand Trousseau","place":["Paris, France"],"department":["Department of Pediatric pain and migraine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Cardin","sequence":"additional","affiliation":[{"name":"Tick-Borne Diseases Reference Center, Paris and Northern Region, Intercommunal Hospital of Villeneuve Saint Georges","place":["Villeneuve-Saint-Georges, France"],"department":["Department of Infectious Diseases"]},{"name":"Tick-Borne Diseases Reference Center, Paris and Northern Region, Intercommunal Hospital of Villeneuve Saint Georges","place":["Villeneuve-Saint-Georges, France"],"department":["Department of Psychology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Costanza","family":"Puppo","sequence":"additional","affiliation":[{"name":"Inserm Unity 1290 RESHAPE, University of Lyon 2","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Chosidow","sequence":"additional","affiliation":[{"name":"Tick-Borne Diseases Reference Center, Paris and Northern Region, Intercommunal Hospital of Villeneuve-Saint-Georges","place":["Villeneuve-Saint-Georges, France"],"department":["Department of Pediatrics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5003-540X","authenticated-orcid":true,"given":"Alice","family":"Raffetin","sequence":"additional","affiliation":[{"name":"Tick-Borne Diseases Reference Center, Paris and Northern Region, Intercommunal Hospital of Villeneuve Saint Georges","place":["Villeneuve-Saint-Georges, France"],"department":["Department of Infectious Diseases"]},{"name":"Inserm Unity U955, GEIC2O, Mondor Institute of Medical Research, University Paris-Est Cr\u00e9teil (UPEC)","place":["Cr\u00e9teil, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"issue":"22","key":"pone.0357185.ref001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss6622a1","article-title":"Surveillance for Lyme Disease - 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