{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:04:28Z","timestamp":1789581868992,"version":"build-2803163510"},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR 203308"],"award-info":[{"award-number":["NIHR 203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR 203308"],"award-info":[{"award-number":["NIHR 203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR 203308"],"award-info":[{"award-number":["NIHR 203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR 203308"],"award-info":[{"award-number":["NIHR 203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR 203308"],"award-info":[{"award-number":["NIHR 203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR 203308"],"award-info":[{"award-number":["NIHR 203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR 203308"],"award-info":[{"award-number":["NIHR 203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>As funders of health and care research increasingly mandate inclusive research practices, the Manchester Biomedical Research Centre (BRC) and Clinical Research Facility (CRF) developed a comprehensive Inclusive Research (IR) Strategy to embed the principles of inclusivity across their experimental medicine research. This paper presents the co-production of the Strategy, shaped by collaboration between Inclusive Research Methods (IRM), Equality, Diversity and Inclusion (EDI), and Patient and Public Involvement and Engagement (PPIE) teams, alongside public contributors and wider stakeholders. The Strategy development was informed by iterative engagement, including workshops and one-to-one consultations, which revealed varying levels of understanding of IR\u00a0and highlighted the need for accessible, evidence-informed approaches. It is structured around five strategic principles: mapping inequalities and protected characteristics; training and capacity building; working with communities and partners; establishing effective routes to delivery and using and creating Inclusive Research Methods. Key learning from the process includes the importance of aligning IR with existing organisational strategies, fostering inclusive governance through our Inclusive Research Oversight Board (IROB), and ensuring flexibility to adapt to emerging national guidance\u2014such as National Institute for Health and Care Research\u2019s (NIHR) 10-step framework for inclusive research design or Core20PLUS5 \u2013 and the ongoing cycles of evaluation across the BRC\/CRF programmes. Stakeholder feedback also underscored the value of co-production, the need to dismantle power dynamics, and the importance of clarity, accountability, and responsiveness in strategic implementation. The IR Strategy demonstrates how inclusive research can be operationalised within a complex translational research infrastructure. It offers a replicable model for embedding inclusive practices across the research lifecycle, leading to more equitable participant recruitment, enhanced research relevance, and health research with greater impact for all, including under-served populations. By fostering team research and an inclusive culture where inclusivity is business as usual, the IR Strategy seeks to drive meaningful change in health and care research, ensuring it is representative, accessible, and beneficial to all over the longer term.<\/jats:p>","DOI":"10.1371\/journal.pone.0357608","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:43:58Z","timestamp":1789580638000},"page":"e0357608","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Developing an inclusive research (methods) strategy for the Manchester Biomedical Research Centre and Clinical Research Facility"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1866-7036","authenticated-orcid":true,"given":"Anna","family":"Coleman","sequence":"first","affiliation":[{"name":"Medicine and Health, University of Manchester","place":["United Kingdom"],"department":["Inclusive Research Methods Team, NIHR Manchester Biomedical Research Centre and Clinical Research Facility, Division of Medical Education, School of Medical Sciences, Faculty of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheela","family":"Medahunsi","sequence":"additional","affiliation":[{"name":"Medicine and Health, University of Manchester","place":["United Kingdom"],"department":["Inclusive Research Methods Team, NIHR Manchester Biomedical Research Centre and Clinical Research Facility, Division of Medical Education, School of Medical Sciences, Faculty of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Elliott","sequence":"additional","affiliation":[{"name":"Medicine and Health, University of Manchester","place":["United Kingdom"],"department":["Inclusive Research Methods Team, NIHR Manchester Biomedical Research Centre and Clinical Research Facility, Division of Medical Education, School of Medical Sciences, Faculty of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6243-7975","authenticated-orcid":true,"given":"Jedidah","family":"Mould","sequence":"additional","affiliation":[{"name":"Medicine and Health, University of Manchester","place":["United Kingdom"],"department":["Inclusive Research Methods Team, NIHR Manchester Biomedical Research Centre and Clinical Research Facility, Division of Medical Education, School of Medical Sciences, Faculty of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abin","family":"Thomas","sequence":"additional","affiliation":[{"name":"Medicine and Health, University of Manchester","place":["United Kingdom"],"department":["Inclusive Research Methods Team, NIHR Manchester Biomedical Research Centre and Clinical Research Facility, Division of Medical Education, School of Medical Sciences, Faculty of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1333-0513","authenticated-orcid":true,"given":"Eliza","family":"Varga","sequence":"additional","affiliation":[{"name":"Medicine and Health, University of Manchester","place":["United Kingdom"],"department":["Inclusive Research Methods Team, NIHR Manchester Biomedical Research Centre and Clinical Research Facility, Division of Medical Education, School of Medical Sciences, Faculty of Biology"]},{"name":"Manchester City Council","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arpana","family":"Verma","sequence":"additional","affiliation":[{"name":"Medicine and Health, University of Manchester","place":["United Kingdom"],"department":["Inclusive Research Methods Team, NIHR Manchester Biomedical Research Centre and Clinical Research Facility, Division of Medical Education, School of Medical Sciences, Faculty of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"issue":"6614","key":"pone.0357608.ref001","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1126\/science.abp9775","article-title":"A framework for sex, gender, and diversity analysis in research","volume":"377","author":"L Hunt","year":"2022","journal-title":"Science"},{"key":"pone.0357608.ref002","unstructured":"National Institute for Health and Care Research. 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Public and Patient Involvement, Engagement and Participation (PPIE) Strategy 2022-2027: Bringing people and health research together for everyone\u2019s benefit. 2022. https:\/\/www.manchesterbrc.nihr.ac.uk\/wp-content\/uploads\/2023\/05\/NIHR-Manchester-BRC-CRF-PPIEP-strategy.pdf"},{"issue":"3","key":"pone.0357608.ref013","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/1467-8551.00193","article-title":"Corporate financial distress and turnaround strategies: an empirical analysis","volume":"12","author":"S Sudarsanam","year":"2001","journal-title":"Br J Manag"},{"key":"pone.0357608.ref014","article-title":"Creating effective strategy implementation: a systematic review of managerial and organizational levers","author":"CG Holm","year":"2025","journal-title":"Rev Manag Sci"},{"key":"pone.0357608.ref015","unstructured":"NHS England. Core20plus5. 2021. https:\/\/www.england.nhs.uk\/about\/equality\/equality-hub\/national-healthcare-inequalities-improvement-programme\/core20plus5\/"},{"key":"pone.0357608.ref016","unstructured":"Ministry of Housing, Communities and Local Government. English Devolution White Paper: Policy Paper. 2024. https:\/\/www.gov.uk\/government\/publications\/english-devolution-white-paper-power-and-partnership-foundations-for-growth\/english-devolution-white-paper"},{"key":"pone.0357608.ref017","unstructured":"WHO. Health in all policies: framework for country action. 2014. https:\/\/www.afro.who.int\/sites\/default\/files\/2017-06\/140120HPRHiAPFramework.pdf"},{"key":"pone.0357608.ref018","unstructured":"Morrow E, Vandrevala T, Ross F. Building inclusive research cultures\u2013 how can we rise above EDI cynicism? Health Education Policy Institute Blog. 2025. https:\/\/www.hepi.ac.uk\/2025\/03\/05\/building-inclusive-research-cultures-how-can-we-rise-above-edi-cynicism\/"},{"key":"pone.0357608.ref019","unstructured":"National Institute for Health and Care Research NIHR. Research Inclusion Strategy 2022-2027. 2022. https:\/\/www.nihr.ac.uk\/about-us\/who-we-are\/research-inclusion\/strategy-2022-27"},{"key":"pone.0357608.ref020","unstructured":"Vocal. 2023. https:\/\/wearevocal.org\/who-we-are"},{"key":"pone.0357608.ref021","volume-title":"Equality, Diversity & Inclusion Strategy 2022-2027","author":"NIHR Manchester Biomedical Research Centre and Clinical Research Facility","year":"2022"},{"key":"pone.0357608.ref022","unstructured":"NIHR Manchester Biomedical Research Centre. Training and Capacity Strategy 2022-2027. 2022."},{"key":"pone.0357608.ref023","unstructured":"Mentimeter Technology. https:\/\/www.mentimeter.com"},{"key":"pone.0357608.ref024","unstructured":"Well Sorted Technology. https:\/\/www.well-sorted.org"},{"issue":"11","key":"pone.0357608.ref025","first-page":"35","article-title":"There\u2019s a SMART way to write management\u2019s goals and objectives","volume":"70","author":"GT Doran","year":"1981","journal-title":"Management Review"},{"issue":"2","key":"pone.0357608.ref026","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1191\/1478088706qp063oa","article-title":"Using thematic analysis in psychology","volume":"3","author":"V Braun","year":"2006","journal-title":"Qualitative Research in Psychology"},{"key":"pone.0357608.ref027","doi-asserted-by":"crossref","first-page":"100198","DOI":"10.1016\/j.glmedi.2025.100198","article-title":"Using thematic analysis in qualitative research","volume":"6","author":"SK Ahmed","year":"2025","journal-title":"Journal of Medicine, Surgery, and Public Health"},{"issue":"2","key":"pone.0357608.ref028","article-title":"Equality, diversity and inclusion strategies of NIHR biomedical research centres and clinical research facilities across England: a qualitative content analysis","volume":"16","author":"P Hua","year":"2026","journal-title":"BMJ Open"},{"key":"pone.0357608.ref029","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/B978-0-12-818630-5.11083-8","article-title":"Rapid qualitative research.","author":"G Chisnall","year":"2023","journal-title":"International Encyclopaedia of Education"},{"key":"pone.0357608.ref030","volume-title":"Realistic Evaluation","author":"R Pawson","year":"1997"},{"key":"pone.0357608.ref031","unstructured":"Towers R. Understanding people in places. 2024. https:\/\/publicpolicydesign.blog.gov.uk\/2024\/03\/15\/understanding-people-in-places\/"},{"key":"pone.0357608.ref032","unstructured":"Pankhurst Institute. Team research. 2023. https:\/\/www.teamresearch.manchester.ac.uk\/glossary\/"},{"issue":"3","key":"pone.0357608.ref033","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1177\/10464964241274119","article-title":"The Science (and Practice) of Teamwork: A Commentary on Forty Years of Progress","volume":"56","author":"E Salas","year":"2024","journal-title":"Small Group Research"},{"key":"pone.0357608.ref034","unstructured":"National Institute for Health and Care Research (NIHR). Equality, Diversity and Inclusion Strategy 2022-2027. 2022. https:\/\/www.nihr.ac.uk\/documents\/equality-diversity-and-inclusion-strategy-2022-2027\/31295"},{"key":"pone.0357608.ref035","unstructured":"National Institute for Health and Care Research NIHR. 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