{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:08:07Z","timestamp":1789063687965,"version":"build-2803163510"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acne vulgaris is associated with psychological morbidity, but clinically diagnosed phobic anxiety disorders (PADs) have been little studied in dermatology settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The analysis comprised 280 patients with acne vulgaris recruited by convenience sampling at a national dermatology hospital in Hanoi, Vietnam, from December 2025 to June 2026. A psychiatrist established PAD diagnoses using ICD-10 clinical criteria; Fear Questionnaire scores were used descriptively to characterize phobic symptoms among diagnosed cases. Multivariable logistic regression estimated adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for factors associated with PADs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>PADs were diagnosed in 69 of 280 participants (24.6%; 95% CI, 20.0%\u201330.0%). Social phobia affected 64 participants (22.9% of the sample; 92.8% of PAD cases), specific phobia affected 26 (9.3%), and agoraphobia affected one (0.4%); subtypes could co-occur. In the exploratory adjusted model, PADs were associated with study-specific anxiety-proneness rating (aOR, 6.90; 95% CI, 2.92\u201316.32), physical comorbidity (aOR, 4.70; 95% CI, 2.30\u20139.60), acne scarring (aOR, 2.29; 95% CI, 1.04\u20135.05), and poor treatment response (aOR, 5.06; 95% CI, 2.20\u201311.62). Clinician-rated severe acne was not associated with PADs after adjustment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this tertiary-care sample, PADs\u2014predominantly social phobia\u2014were common. Associations with scarring, treatment response, physical comorbidity, and study-specific anxiety-proneness warrant confirmation in prospective multicentre studies using standardized psychosocial and treatment-response measures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0357803","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T17:31:12Z","timestamp":1789061472000},"page":"e0357803","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Phobic anxiety disorders among patients with acne vulgaris at a national dermatology hospital in Vietnam: Prevalence, clinical phenotype, and associated factors"],"prefix":"10.1371","volume":"21","author":[{"given":"Nguyen Van","family":"Tuan","sequence":"first","affiliation":[{"name":"Hanoi Medical University","place":["Vietnam"]},{"name":"National Institute of Mental Health - Bach Mai Hospital","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8516-2081","authenticated-orcid":true,"given":"Vu Thai","family":"Ha","sequence":"additional","affiliation":[{"name":"Hanoi Medical University","place":["Vietnam"]},{"name":"National Hospital of Dermatology and Venereology","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6896-2302","authenticated-orcid":true,"given":"Mai Son","family":"Duong","sequence":"additional","affiliation":[{"name":"Hanoi Medical University","place":["Vietnam"]},{"name":"National Institute of Mental Health - 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