{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:00:33Z","timestamp":1790359233047,"version":"4.1.0"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Childhood anaemia remains a major public health problem in Peru. Although several maternal and environmental factors have been implicated, the association between maternal body mass index (BMI) and anaemia in young children remains inconsistent. This study aimed to evaluate the association between maternal BMI and both anaemia and haemoglobin levels in children aged 6\u201359 months in Peru.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional analytical study using data from the 2024 Peruvian Demographic and Family Health Survey. Children aged 6\u201359 months and their mothers were included. Maternal BMI was the exposure variable, while childhood anaemia and haemoglobin concentration were the outcomes. Poisson regression was used to estimate prevalence ratios for anaemia, and linear regression models were applied to assess associations with haemoglobin levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 16,973 children were analysed. In adjusted analyses, maternal BMI categories were not associated with anaemia prevalence. However, maternal obesity, compared to normal weight, was associated with higher haemoglobin levels in children (adjusted \u03b2 0.72 g\/dL; 95% CI 0.23 to 1.22). Additionally, each 1 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      increase in maternal BMI was associated with a 0.07 g\/dL increase in child haemoglobin (adjusted \u03b2 0.07; 95% CI 0.03 to 0.11).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Maternal body mass index was not associated with the prevalence of anaemia, although a positive association was observed with child haemoglobin levels. These findings support the inclusion of maternal nutritional status within comprehensive anaemia prevention strategies and highlight the need for longitudinal studies to confirm these associations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0359236","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:33:18Z","timestamp":1790357598000},"page":"e0359236","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maternal body mass index and child haemoglobin: A national cross-sectional study in Peru"],"prefix":"10.1371","volume":"21","author":[{"given":"Arnold F.","family":"Julca Avalos","sequence":"first","affiliation":[{"name":"Universidad Peruana Uni\u00f3n","place":["Lima, Peru"],"department":["School of Medicine, Faculty of Health Sciences"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeniffer K.","family":"Pastor Aponte","sequence":"additional","affiliation":[{"name":"Universidad Peruana Uni\u00f3n","place":["Lima, Peru"],"department":["School of Medicine, Faculty of Health Sciences"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor A.","family":"Ramos Berrocal","sequence":"additional","affiliation":[{"name":"Universidad Peruana Uni\u00f3n","place":["Lima, Peru"],"department":["School of Medicine, Faculty of Health Sciences"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3690-0014","authenticated-orcid":true,"given":"David R.","family":"Soriano-Moreno","sequence":"additional","affiliation":[{"name":"Universidad Peruana Uni\u00f3n","place":["Lima, Peru"],"department":["School of Medicine, Faculty of Health Sciences"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"pone.0359236.ref001","article-title":"Prevalence and associated factors of iron deficiency and iron deficiency anemia among under-5 children: A systematic review and meta-analysis","volume":"9","author":"S Gedfie","year":"2022","journal-title":"Glob Pediatr Health"},{"key":"pone.0359236.ref002","doi-asserted-by":"crossref","DOI":"10.1016\/S2352-3026(23)00160-6","article-title":"Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990\u20132021: findings from the Global Burden of Disease Study 2021","volume":"10","author":"WM Gardner","year":"2023","journal-title":"Lancet Haematol"},{"key":"pone.0359236.ref003","doi-asserted-by":"crossref","first-page":"5915","DOI":"10.3390\/nu6125915","article-title":"The impact of anemia on child mortality: An updated review","volume":"6","author":"SP Scott","year":"2014","journal-title":"Nutrients"},{"key":"pone.0359236.ref004","doi-asserted-by":"crossref","first-page":"1474664","DOI":"10.3389\/fnut.2024.1474664","article-title":"Global burden of anemia and cause among children under five years 1990-2019: Findings from the global burden of disease study 2019","volume":"11","author":"Y Liu","year":"2024","journal-title":"Front Nutr"},{"key":"pone.0359236.ref005","author":"Instituto Nacional de Estad\u00edstica e Inform\u00e1tica","year":"2024"},{"issue":"6","key":"pone.0359236.ref006","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0287703","article-title":"Effects of iron supplementation on cognitive development in school-age children: Systematic review and meta-analysis","volume":"18","author":"BT Gutema","year":"2023","journal-title":"PLoS One"},{"issue":"4","key":"pone.0359236.ref007","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/nure.12102","article-title":"Nutrition and brain development in early life","volume":"72","author":"EL Prado","year":"2014","journal-title":"Nutr Rev"},{"issue":"1","key":"pone.0359236.ref008","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1186\/s12889-025-22561-2","article-title":"Socioeconomic inequality in the prevalence of anemia: decomposing analysis among Kurdish people","volume":"25","author":"Y Moradi","year":"2025","journal-title":"BMC Public Health"},{"key":"pone.0359236.ref009","doi-asserted-by":"crossref","first-page":"1068083","DOI":"10.3389\/fpubh.2023.1068083","article-title":"Inequalities in anemia among Peruvian children aged 6-59\u2009months: A decomposition analysis","volume":"11","author":"A Al-Kassab-C\u00f3rdova","year":"2023","journal-title":"Front Public Health"},{"issue":"23","key":"pone.0359236.ref010","doi-asserted-by":"crossref","first-page":"5125","DOI":"10.3390\/nu14235125","article-title":"The effect of maternal overweight and obesity pre-pregnancy and during childhood in the development of obesity in children and adolescents: A systematic literature review","volume":"14","author":"A Mannino","year":"2022","journal-title":"Nutrients"},{"issue":"6","key":"pone.0359236.ref011","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002817","article-title":"The association between maternal body mass index and child obesity: A systematic review and meta-analysis","volume":"16","author":"N Heslehurst","year":"2019","journal-title":"PLoS Med"},{"issue":"4","key":"pone.0359236.ref012","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/osp4.499","article-title":"Longitudinal patterns of food insecurity, the home food environment, and parent feeding practices during COVID-19","volume":"7","author":"EL Adams","year":"2021","journal-title":"Obes Sci Pract"},{"issue":"1","key":"pone.0359236.ref013","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1186\/s41043-025-00966-4","article-title":"Association of food insecurity with anemia in children and adolescents: A systematic review and meta-analysis of observational studies","volume":"44","author":"SP Moosavian","year":"2025","journal-title":"J Health Popul Nutr"},{"key":"pone.0359236.ref014","doi-asserted-by":"crossref","first-page":"6258","DOI":"10.1038\/s41598-022-10216-w","article-title":"The impact of maternal influences on childhood obesity","volume":"12","author":"PC Hsu","year":"2022","journal-title":"Sci Rep"},{"issue":"3","key":"pone.0359236.ref015","doi-asserted-by":"crossref","first-page":"159","DOI":"10.5114\/pedm.2021.107721","article-title":"The influence of maternal nutritional behavior on the nutritional behavior of children with excess body weight","volume":"27","author":"K Str\u0105czek","year":"2021","journal-title":"Pediatr Endocrinol Diabetes Metab"},{"key":"pone.0359236.ref016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.61440\/JCMHC.2025.v2.41","article-title":"Maternal risk factors associated with anaemia among children in Nigeria: A cross-sectional study","author":"ZE Amine","year":"2025","journal-title":"J Clin Med Health Care"},{"issue":"5","key":"pone.0359236.ref017","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-019654","article-title":"Individual, maternal and household risk factors for anaemia among young children in sub-Saharan Africa: a cross-sectional study","volume":"8","author":"PP Moschovis","year":"2018","journal-title":"BMJ Open"},{"issue":"9","key":"pone.0359236.ref018","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/s41430-024-01453-5","article-title":"Birth weight mediates the association of maternal undernutrition with child undernutrition prevalence in West Africa","volume":"78","author":"A Kofi Amegah","year":"2024","journal-title":"Eur J Clin Nutr"},{"issue":"4","key":"pone.0359236.ref019","doi-asserted-by":"crossref","DOI":"10.1111\/mcn.13549","article-title":"Exploring the magnitude and drivers of the double burden of malnutrition at maternal and dyad levels in peri-urban Peru: A cross-sectional study of low-income mothers, infants and young children","volume":"19","author":"R Pradeilles","year":"2023","journal-title":"Matern Child Nutr"},{"key":"pone.0359236.ref020","unstructured":"Instituto Nacional de Estad\u00edstica e Inform\u00e1tica. Encuesta demogr\u00e1fica y de salud familiar - ENDES 2024. 2024."},{"key":"pone.0359236.ref021","author":"Ministerio de Salud","year":"2024"},{"key":"pone.0359236.ref022","author":"World Health Organization","year":"1995"},{"key":"pone.0359236.ref023","unstructured":"Instituto Nacional de Estad\u00edstica e Inform\u00e1tica - INEI. Plataforma Nacional de Datos Abiertos: Encuesta Demogr\u00e1fica y de Salud Familiar (ENDES) 2024. 2024. Available: https:\/\/proyectos.inei.gob.pe\/microdatos\/"},{"key":"pone.0359236.ref024","article-title":"A crash course in good and bad controls","author":"C Cinelli","year":"2020","journal-title":"SSRN Journal"},{"issue":"3","key":"pone.0359236.ref025","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S2213-8587(24)00316-4","article-title":"Definition and diagnostic criteria of clinical obesity","volume":"13","author":"F Rubino","year":"2025","journal-title":"Lancet Diabetes Endocrinol"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0359236","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:33:24Z","timestamp":1790357604000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0359236"}},"subtitle":[],"editor":[{"given":"Marly A.","family":"Cardoso","sequence":"first","affiliation":[{"name":"Universidade de Sao Paulo Faculdade de Saude Publica","place":["BRAZIL"]}],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":25,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0359236","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]}}}