{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:56:01Z","timestamp":1792173361549,"version":"4.4.0"},"reference-count":46,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology Plan Joint Program of Liaoning Province","award":["2024-BSLH-132"],"award-info":[{"award-number":["2024-BSLH-132"]}]},{"name":"2026 College Student Innovation and Entrepreneurship Project"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:p>Herein, we proposed a mild and effective approach for the surface modification of wool fiber using a natural deep eutectic solvent (NADES) composed of choline chloride and ascorbic acid (Vitamin C), avoiding the unsustainability of oxidation methods and severe damage of enzyme methods. The results showed that the NADES could remove keratin-associated proteins partly due to the breakage of disulfide bonds with the retention of the protein\u2019s main macromolecular skeleton and secondary structure, and the exposure degree increase of hydrophilic groups. Furthermore, the hydrophily, dye performance, and anti-felting properties were improved and met industrial standards. The developed method had apparent advances in treatment time, energy consumption, and chemical usage compared to present methods. This work contributes to the further investigation of NADES on the protein modification.<\/jats:p>","DOI":"10.1371\/journal.pone.0360539","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:33:40Z","timestamp":1792172020000},"page":"e0360539","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["A mild, effective, and green micro-dissolution treatment for wool fiber using choline-ascorbic acid NADES"],"prefix":"10.1371","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6143-8284","authenticated-orcid":true,"given":"Zhe","family":"Jiang","sequence":"first","affiliation":[{"name":"Public Security School, Liaoning Police College","place":["Dalian City, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"issue":"42","key":"pone.0360539.ref001","doi-asserted-by":"crossref","first-page":"5705","DOI":"10.1002\/smll.201500502","article-title":"Subtractive structural modification of morpho butterfly wings","volume":"11","author":"Q Shen","year":"2015","journal-title":"Small"},{"key":"pone.0360539.ref002","doi-asserted-by":"crossref","first-page":"100346","DOI":"10.1016\/j.colcom.2020.100346","article-title":"Additive and subtractive modification of butterfly wing structural colors","volume":"40","author":"K Kert\u00e9sz","year":"2021","journal-title":"Colloid Interface Sci Communications"},{"issue":"1","key":"pone.0360539.ref003","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1021\/acs.nanolett.8b02902","article-title":"Unveiling the Intrinsic Cycle Reversibility of a LiCoO2 Electrode at 4.8-V Cutoff Voltage through Subtractive Surface Modification for Lithium-Ion Batteries","volume":"19","author":"WM Seong","year":"2019","journal-title":"Nano Lett"},{"issue":"3","key":"pone.0360539.ref004","first-page":"496","article-title":"Keratin - based materials for biomedical applications","volume":"5","author":"S Feroz","year":"2020","journal-title":"Bioact Mater"},{"key":"pone.0360539.ref005","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jare.2019.01.014","article-title":"A review of the sustainable methods in imparting shrink resistance to wool fabrics","volume":"18","author":"MM Hassan","year":"2019","journal-title":"J Adv Res"},{"issue":"2","key":"pone.0360539.ref006","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1080\/15440478.2020.1745128","article-title":"Advancements in applications of natural wool fiber: Review","volume":"19","author":"F Allafi","year":"2020","journal-title":"J Natural Fibers"},{"key":"pone.0360539.ref007","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1177\/004051750407400616","article-title":"DCCA shrinkproofing of wool. 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