{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T03:41:19Z","timestamp":1783741279470,"version":"3.55.0"},"reference-count":13,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2008,9,12]],"date-time":"2008-09-12T00:00:00Z","timestamp":1221177600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1000156","type":"journal-article","created":{"date-parts":[[2008,9,11]],"date-time":"2008-09-11T17:56:28Z","timestamp":1221155788000},"page":"e1000156","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":83,"title":["BSE Case Associated with Prion Protein Gene Mutation"],"prefix":"10.1371","volume":"4","author":[{"given":"J\u00fcrgen A.","family":"Richt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Mark","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2008,9,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1750-3639.1998.tb00171.x","article-title":"The prion diseases.","volume":"8","author":"SB Prusiner","year":"1998","journal-title":"Brain Pathol"},{"key":"ref2","first-page":"91","article-title":"The neuropathology and epidemiology of bovine spongiform encephalopathy.","volume":"5","author":"GA Wells","year":"1995","journal-title":"Brain Pathol 1995"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/S0140-6736(05)67218-2","article-title":"The origin of bovine spongiform encephalopathy: the human prion disease hypothesis.","volume":"366","author":"AC Colchester","year":"2005","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1177\/104063870701900202","article-title":"Identification and characterization of two bovine spongiform encephalopathy cases diagnosed in the United States.","volume":"19","author":"JA Richt","year":"2007","journal-title":"J Vet Diagn Invest"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1128\/JCM.00160-07","article-title":"Molecular discrimination of atypical bovine spongiform encephalopathy strains from a geographical region spanning a wide area in Europe.","volume":"45","author":"JG Jacobs","year":"2007","journal-title":"J Clin Microbiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"5625","DOI":"10.1016\/j.vaccine.2006.10.058","article-title":"Atypical transmissible spongiform encephalopathies (TSEs) in ruminants.","volume":"25","author":"T Baron","year":"2007","journal-title":"Vaccine"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/s00439-005-0020-1","article-title":"Genetic prion disease: the EUROCJD experience.","volume":"118","author":"GG Kovacs","year":"2005","journal-title":"Hum Genet"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e1830","DOI":"10.1371\/journal.pone.0001830","article-title":"Association of a bovine prion gene haplotype with atypical BSE.","volume":"3","author":"ML Clawson","year":"2008","journal-title":"PLoS ONE"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.3201\/eid1212.060750","article-title":"Spongiform encephalopathy in a miniature zebu.","volume":"12","author":"T Seuberlich","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"ref10","first-page":"1050","article-title":"Inherited Prion Diseases.","author":"Q Kong","year":"2004"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"e2912","DOI":"10.1371\/journal.pone.0002912","article-title":"Identification of a heritable polymorphism in bovine <italic>PRNP<\/italic> associated with genetic transmissible spongiform encephalopathy: evidence of heritable BSE.","volume":"3","author":"EN Nicholson","year":"2008","journal-title":"PLoS ONE"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1746-6148-4-25","article-title":"Prevalence of the prion gene E211K variant in U.S. cattle.","volume":"4","author":"MP Heaton","year":"2008","journal-title":"BMC Vet Res"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1139\/g03-124","article-title":"Prion protein gene sequence of Canada&apos;s first non-imported case of bovine spongiform encephalopathy (BSE).","volume":"46","author":"MB Coulthart","year":"2003","journal-title":"Genome"}],"container-title":["PLoS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1000156","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T05:46:53Z","timestamp":1540273613000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1000156"}},"subtitle":[],"editor":[{"given":"David","family":"Westaway","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2008,9,12]]},"references-count":13,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2008,9,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1000156","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,12]]}}}