{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:44:07Z","timestamp":1793087047997,"version":"4.5.0"},"reference-count":135,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2010,5,13]],"date-time":"2010-05-13T00:00:00Z","timestamp":1273708800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1000900","type":"journal-article","created":{"date-parts":[[2010,5,13]],"date-time":"2010-05-13T20:05:07Z","timestamp":1273781107000},"page":"e1000900","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":109,"title":["Listeria monocytogenes Internalin B Activates Junctional Endocytosis to Accelerate Intestinal Invasion"],"prefix":"10.1371","volume":"6","author":[{"given":"Mickey","family":"Pentecost","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyothi","family":"Kumaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Partho","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel R.","family":"Amieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2010,5,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1128\/CMR.14.3.584-640.2001","article-title":"Listeria pathogenesis and molecular virulence determinants.","volume":"14","author":"JA Vazquez-Boland","year":"2001","journal-title":"Clin Microbiol Rev"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1365-2958.1995.tb02297.x","article-title":"Entry of Listeria monocytogenes into hepatocytes requires expression of inIB, a surface protein of the internalin multigene family.","volume":"16","author":"S Dramsi","year":"1995","journal-title":"Mol Microbiol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/0092-8674(91)90009-N","article-title":"Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci.","volume":"65","author":"JL Gaillard","year":"1991","journal-title":"Cell"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1242\/jcs.107.10.2951","article-title":"Exploitation of microfilament proteins by Listeria monocytogenes: microvillus-like composition of the comet tails and vectorial spreading in polarized epithelial sheets.","volume":"107 (Pt 10)","author":"CJ Temm-Grove","year":"1994","journal-title":"J Cell Sci"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/nrmicro2112","article-title":"Life on the inside: the intracellular lifestyle of cytosolic bacteria.","volume":"7","author":"K Ray","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1126\/science.1059852","article-title":"A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier.","volume":"292","author":"M Lecuit","year":"2001","journal-title":"Science"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0092-8674(00)81070-3","article-title":"E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells.","volume":"84","author":"J Mengaud","year":"1996","journal-title":"Cell"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0092-8674(02)01136-4","article-title":"Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin.","volume":"111","author":"WD Schubert","year":"2002","journal-title":"Cell"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3956","DOI":"10.1093\/emboj\/18.14.3956","article-title":"A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes.","volume":"18","author":"M Lecuit","year":"1999","journal-title":"Embo J"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0092-8674(00)00141-0","article-title":"InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase.","volume":"103","author":"Y Shen","year":"2000","journal-title":"Cell"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1600-0854.2005.00290.x","article-title":"The listeria protein internalin B mimics hepatocyte growth factor-induced receptor trafficking.","volume":"6","author":"N Li","year":"2005","journal-title":"Traffic"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"5260","DOI":"10.1128\/IAI.66.11.5260-5267.1998","article-title":"Interaction of Listeria monocytogenes with human brain microvascular endothelial cells: InlB-dependent invasion, long-term intracellular growth, and spread from macrophages to endothelial cells.","volume":"66","author":"L Greiffenberg","year":"1998","journal-title":"Infect Immun"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"3896","DOI":"10.1128\/IAI.63.10.3896-3903.1995","article-title":"Expression of the Listeria monocytogenes EGD inlA and inlB genes, whose products mediate bacterial entry into tissue culture cell lines, by PrfA-dependent and -independent mechanisms.","volume":"63","author":"A Lingnau","year":"1995","journal-title":"Infect Immun"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1046\/j.1365-2958.1998.00776.x","article-title":"Internalin B is essential for adhesion and mediates the invasion of Listeria monocytogenes into human endothelial cells.","volume":"28","author":"SK Parida","year":"1998","journal-title":"Mol Microbiol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1365-2958.2003.03968.x","article-title":"GW domains of the Listeria monocytogenes invasion protein InlB are required for potentiation of Met activation.","volume":"52","author":"M Banerjee","year":"2004","journal-title":"Mol Microbiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"5623","DOI":"10.1093\/emboj\/cdf558","article-title":"GW domains of the Listeria monocytogenes invasion protein InlB are SH3-like and mediate binding to host ligands.","volume":"21","author":"M Marino","year":"2002","journal-title":"Embo J"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"7783","DOI":"10.1074\/jbc.M211666200","article-title":"Multiple regions of internalin B contribute to its ability to turn on the Ras-mitogen-activated protein kinase pathway.","volume":"278","author":"J Copp","year":"2003","journal-title":"J Biol Chem"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/S1097-2765(00)80234-8","article-title":"Structure of the lnlB leucine-rich repeats, a domain that triggers host cell invasion by the bacterial pathogen L. monocytogenes.","volume":"4","author":"M Marino","year":"1999","journal-title":"Mol Cell"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"17025","DOI":"10.1074\/jbc.274.24.17025","article-title":"The Listeria monocytogenes protein InlB is an agonist of mammalian phosphoinositide 3-kinase.","volume":"274","author":"K Ireton","year":"1999","journal-title":"J Biol Chem"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1038\/nature07303","article-title":"Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis.","volume":"455","author":"O Disson","year":"2008","journal-title":"Nature"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cell.2007.05.037","article-title":"Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB.","volume":"130","author":"HH Niemann","year":"2007","journal-title":"Cell"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1084\/jem.183.2.359","article-title":"The inlAB locus mediates the entry of Listeria monocytogenes into hepatocytes in vivo.","volume":"183","author":"JL Gaillard","year":"1996","journal-title":"J Exp Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1365-2958.2004.04138.x","article-title":"FbpA, a novel multifunctional Listeria monocytogenes virulence factor.","volume":"53","author":"S Dramsi","year":"2004","journal-title":"Mol Microbiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1462-5822.2005.00634.x","article-title":"Species specificity of the Listeria monocytogenes InlB protein.","volume":"8","author":"N Khelef","year":"2006","journal-title":"Cell Microbiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1128\/IAI.72.1.489-497.2004","article-title":"Listeriosis in the pregnant guinea pig: a model of vertical transmission.","volume":"72","author":"AI Bakardjiev","year":"2004","journal-title":"Infect Immun"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"e1000732","DOI":"10.1371\/journal.ppat.1000732","article-title":"Placental syncytiotrophoblast constitutes a major barrier to vertical transmission of Listeria monocytogenes.","volume":"6","author":"JR Robbins","year":"2010","journal-title":"PLoS Pathog"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1111\/j.1462-5822.2008.01200.x","article-title":"Successive post-translational modifications of E-cadherin are required for InlA-mediated internalization of Listeria monocytogenes.","volume":"10","author":"M Bonazzi","year":"2008","journal-title":"Cell Microbiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1111\/j.1462-5822.2007.00984.x","article-title":"Src, cortactin and Arp2\/3 complex are required for E-cadherin-mediated internalization of Listeria into cells.","volume":"9","author":"S Sousa","year":"2007","journal-title":"Cell Microbiol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1046\/j.1365-2958.2002.02767.x","article-title":"InlA- but not InlB-mediated internalization of Listeria monocytogenes by non-phagocytic mammalian cells needs the support of other internalins.","volume":"43","author":"B Bergmann","year":"2002","journal-title":"Mol Microbiol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1371\/journal.ppat.0020003","article-title":"Listeria monocytogenes invades the epithelial junctions at sites of cell extrusion.","volume":"2","author":"M Pentecost","year":"2006","journal-title":"PLoS Pathog"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1083\/jcb.125.2.313","article-title":"Targeting of the SF\/HGF receptor to the basolateral domain of polarized epithelial cells.","volume":"125","author":"T Crepaldi","year":"1994","journal-title":"J Cell Biol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/BF02818615","article-title":"Interactions of the bacterial pathogen Listeria monocytogenes with mammalian cells: bacterial factors, cellular ligands, and signaling.","volume":"43","author":"P Cossart","year":"1998","journal-title":"Folia Microbiol (Praha)"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1083\/jcb.100.1.327","article-title":"Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells.","volume":"100","author":"K Boller","year":"1985","journal-title":"J Cell Biol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1242\/dev.110.4.1001","article-title":"Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt.","volume":"110","author":"CS Potten","year":"1990","journal-title":"Development"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF01868675","article-title":"Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physiological rearrangement of tight junctions.","volume":"116","author":"JL Madara","year":"1990","journal-title":"J Membr Biol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0955-0674(94)90047-7","article-title":"Differentiation and self-renewal in the mouse gastrointestinal epithelium.","volume":"6","author":"JI Gordon","year":"1994","journal-title":"Curr Opin Cell Biol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/sj.cdd.4400634","article-title":"Changes in intercellular junctions during apoptosis precede nuclear condensation or phosphatidylserine exposure on the cell surface.","volume":"7","author":"BM Corfe","year":"2000","journal-title":"Cell Death Differ"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1016\/S0960-9822(01)00587-5","article-title":"An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism.","volume":"11","author":"J Rosenblatt","year":"2001","journal-title":"Curr Biol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"3843","DOI":"10.1099\/mic.0.27257-0","article-title":"sigmaB-dependent gene induction and expression in Listeria monocytogenes during osmotic and acid stress conditions simulating the intestinal environment.","volume":"150","author":"D Sue","year":"2004","journal-title":"Microbiology"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1128\/AEM.02664-06","article-title":"The alternative sigma factor sigma B and the virulence gene regulator PrfA both regulate transcription of Listeria monocytogenes internalins.","volume":"73","author":"P McGann","year":"2007","journal-title":"Appl Environ Microbiol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/nature08080","article-title":"The Listeria transcriptional landscape from saprophytism to virulence.","volume":"459","author":"A Toledo-Arana","year":"2009","journal-title":"Nature"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1099\/mic.0.030205-0","article-title":"The interaction between Listeria monocytogenes and the host gastrointestinal tract.","volume":"155","author":"RD Sleator","year":"2009","journal-title":"Microbiology"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1038\/nri1461","article-title":"Immune responses to Listeria monocytogenes.","volume":"4","author":"EG Pamer","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.cell.2007.03.049","article-title":"Extending the host range of Listeria monocytogenes by rational protein design.","volume":"129","author":"T Wollert","year":"2007","journal-title":"Cell"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"13960","DOI":"10.1073\/pnas.0702199104","article-title":"Thermodynamically reengineering the listerial invasion complex InlA\/E-cadherin.","volume":"104","author":"T Wollert","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"6776","DOI":"10.1038\/sj.onc.1203114","article-title":"Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells\u2013regulation by Rho, Rac and Rab small G proteins.","volume":"18","author":"T Kamei","year":"1999","journal-title":"Oncogene"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/ncb758","article-title":"Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.","volume":"4","author":"Y Fujita","year":"2002","journal-title":"Nat Cell Biol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1083\/jcb.146.6.1333","article-title":"Listeria monocytogenes exploits normal host cell processes to spread from cell to cell.","volume":"146","author":"JR Robbins","year":"1999","journal-title":"J Cell Biol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"15065","DOI":"10.1074\/jbc.M610926200","article-title":"Functional genomic studies of the intestinal response to a foodborne enteropathogen in a humanized gnotobiotic mouse model.","volume":"282","author":"M Lecuit","year":"2007","journal-title":"J Biol Chem"},{"key":"ref50","first-page":"694","article-title":"Experimental Listeria enteritis. I. An electron microscopic study of the epithelial phase in experimental listeria infection.","volume":"26","author":"P Racz","year":"1972","journal-title":"Lab Invest"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1083\/jcb.109.4.1597","article-title":"Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes.","volume":"109","author":"LG Tilney","year":"1989","journal-title":"J Cell Biol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1046\/j.1365-2958.1999.01652.x","article-title":"Interaction between the protein InlB of Listeria monocytogenes and lipoteichoic acid: a novel mechanism of protein association at the surface of gram-positive bacteria.","volume":"34","author":"R Jonquieres","year":"1999","journal-title":"Mol Microbiol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1046\/j.1365-2958.2001.02704.x","article-title":"Synergy between the N- and C-terminal domains of InlB for efficient invasion of non-phagocytic cells by Listeria monocytogenes.","volume":"42","author":"R Jonquieres","year":"2001","journal-title":"Mol Microbiol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1046\/j.1365-2958.1999.01560.x","article-title":"The 213-amino-acid leucine-rich repeat region of the listeria monocytogenes InlB protein is sufficient for entry into mammalian cells, stimulation of PI 3-kinase and membrane ruffling.","volume":"34","author":"L Braun","year":"1999","journal-title":"Mol Microbiol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.chom.2007.10.001","article-title":"Invasive and adherent bacterial pathogens co-Opt host clathrin for infection.","volume":"2","author":"E Veiga","year":"2007","journal-title":"Cell Host Microbe"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/j.1462-5822.2006.00832.x","article-title":"A FRET analysis to unravel the role of cholesterol in Rac1 and PI 3-kinase activation in the InlB\/Met signalling pathway.","volume":"9","author":"S Seveau","year":"2007","journal-title":"Cell Microbiol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1083\/jcb.200104037","article-title":"A role for cofilin and LIM kinase in Listeria-induced phagocytosis.","volume":"155","author":"H Bierne","year":"2001","journal-title":"J Cell Biol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1083\/jcb.200406078","article-title":"Role of lipid rafts in E-cadherin\u2013and HGF-R\/Met\u2013mediated entry of Listeria monocytogenes into host cells.","volume":"166","author":"S Seveau","year":"2004","journal-title":"J Cell Biol"},{"key":"ref59","article-title":"Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells.","author":"E Veiga","year":"2005","journal-title":"Nat Cell Biol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1242\/jcs.02285","article-title":"WASP-related proteins, Abi1 and Ena\/VASP are required for Listeria invasion induced by the Met receptor.","volume":"118","author":"H Bierne","year":"2005","journal-title":"J Cell Sci"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1046\/j.1365-2958.1998.00750.x","article-title":"The InIB protein of Listeria monocytogenes is sufficient to promote entry into mammalian cells.","volume":"27","author":"L Braun","year":"1998","journal-title":"Mol Microbiol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0962-8924(02)00006-5","article-title":"Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions.","volume":"13","author":"P Cossart","year":"2003","journal-title":"Trends Cell Biol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1111\/j.1462-5822.2007.00933.x","article-title":"Entry of the bacterial pathogen Listeria monocytogenes into mammalian cells.","volume":"9","author":"K Ireton","year":"2007","journal-title":"Cell Microbiol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"12221","DOI":"10.1073\/pnas.211106398","article-title":"Microinjection and growth of bacteria in the cytosol of mammalian host cells.","volume":"98","author":"M Goetz","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"5137","DOI":"10.1128\/IAI.65.12.5137-5141.1997","article-title":"Internalin B promotes the replication of Listeria monocytogenes in mouse hepatocytes.","volume":"65","author":"SH Gregory","year":"1997","journal-title":"Infect Immun"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"3471","DOI":"10.1074\/jbc.272.6.3471","article-title":"Hepatocyte growth factor alters the polarity of Madin-Darby canine kidney cell monolayers.","volume":"272","author":"DF Balkovetz","year":"1997","journal-title":"J Biol Chem"},{"key":"ref67","first-page":"1085","article-title":"Potent and selective inhibitors of the Met [hepatocyte growth factor\/scatter factor (HGF\/SF) receptor] tyrosine kinase block HGF\/SF-induced tumor cell growth and invasion.","volume":"2","author":"X Wang","year":"2003","journal-title":"Mol Cancer Ther"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"3357","DOI":"10.1242\/jcs.115.17.3357","article-title":"InlB, a surface protein of Listeria monocytogenes that behaves as an invasin and a growth factor.","volume":"115","author":"H Bierne","year":"2002","journal-title":"J Cell Sci"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1128\/IAI.62.8.3554-3558.1994","article-title":"Ultrastructural study of Listeria monocytogenes entry into cultured human colonic epithelial cells.","volume":"62","author":"I Karunasagar","year":"1994","journal-title":"Infect Immun"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.bbamem.2007.07.012","article-title":"Adherens and tight junctions: structure, function and connections to the actin cytoskeleton.","volume":"1778","author":"A Hartsock","year":"2008","journal-title":"Biochim Biophys Acta"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1083\/jcb.200401078","article-title":"Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments.","volume":"166","author":"G Izumi","year":"2004","journal-title":"J Cell Biol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1242\/jcs.000653","article-title":"EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin.","volume":"120","author":"DM Bryant","year":"2007","journal-title":"J Cell Sci"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1111\/j.1462-5822.2007.00967.x","article-title":"Type II phosphatidylinositol 4-kinases promote Listeria monocytogenes entry into target cells.","volume":"9","author":"J Pizarro-Cerda","year":"2007","journal-title":"Cell Microbiol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.devcel.2006.04.002","article-title":"Dynasore, a cell-permeable inhibitor of dynamin.","volume":"10","author":"E Macia","year":"2006","journal-title":"Dev Cell"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.bbamem.2008.10.028","article-title":"Tight junctions as targets of infectious agents.","volume":"1788","author":"JA Guttman","year":"2009","journal-title":"Biochim Biophys Acta"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ceb.2003.12.002","article-title":"Breaking into the epithelial apical-junctional complex\u2013news from pathogen hackers.","volume":"16","author":"R Vogelmann","year":"2004","journal-title":"Curr Opin Cell Biol"},{"key":"ref77","article-title":"Microbial strategies to target, cross or disrupt epithelia.","author":"S Sousa","year":"2005","journal-title":"Curr Opin Cell Biol"},{"key":"ref78","first-page":"7008","article-title":"Mechanisms of intestinal tight junctional disruption during infection.","volume":"13","author":"JR O'Hara","year":"2008","journal-title":"Front Biosci"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.ejcb.2005.08.002","article-title":"Cellular adhesion molecules as targets for bacterial infection.","volume":"85","author":"CR Hauck","year":"2006","journal-title":"Eur J Cell Biol"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.chom.2007.07.003","article-title":"Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5.","volume":"2","author":"CB Coyne","year":"2007","journal-title":"Cell Host Microbe"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1126\/science.275.5304.1320","article-title":"Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5.","volume":"275","author":"JM Bergelson","year":"1997","journal-title":"Science"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.chom.2008.12.001","article-title":"Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus.","volume":"5","author":"AA Antar","year":"2009","journal-title":"Cell Host Microbe"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0092-8674(01)00231-8","article-title":"Junction adhesion molecule is a receptor for reovirus.","volume":"104","author":"ES Barton","year":"2001","journal-title":"Cell"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1128\/JVI.01888-08","article-title":"Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection.","volume":"83","author":"S Liu","year":"2009","journal-title":"J Virol"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"8643","DOI":"10.1074\/jbc.M709824200","article-title":"Correlation of the tight junction-like distribution of Claudin-1 to the cellular tropism of hepatitis C virus.","volume":"283","author":"W Yang","year":"2008","journal-title":"J Biol Chem"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/nature05654","article-title":"Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry.","volume":"446","author":"MJ Evans","year":"2007","journal-title":"Nature"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"7203","DOI":"10.1128\/JVI.76.14.7203-7208.2002","article-title":"Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabies virus entry.","volume":"76","author":"M Yoon","year":"2002","journal-title":"J Virol"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1462-5822.2004.00389.x","article-title":"Herpes simplex virus: receptors and ligands for cell entry.","volume":"6","author":"PG Spear","year":"2004","journal-title":"Cell Microbiol"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"9969","DOI":"10.1128\/JVI.77.18.9969-9978.2003","article-title":"Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entry.","volume":"77","author":"KL Graham","year":"2003","journal-title":"J Virol"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1128\/JVI.76.3.1109-1123.2002","article-title":"VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment.","volume":"76","author":"M Ciarlet","year":"2002","journal-title":"J Virol"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"14644","DOI":"10.1073\/pnas.250299897","article-title":"Integrin alpha(v)beta(3) mediates rotavirus cell entry.","volume":"97","author":"CA Guerrero","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1128\/JVI.74.1.228-236.2000","article-title":"Integrins alpha2beta1 and alpha4beta1 can mediate SA11 rotavirus attachment and entry into cells.","volume":"74","author":"MJ Hewish","year":"2000","journal-title":"J Virol"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1128\/IAI.66.3.1237-1243.1998","article-title":"M-cell surface beta1 integrin expression and invasin-mediated targeting of Yersinia pseudotuberculosis to mouse Peyer&apos;s patch M cells.","volume":"66","author":"MA Clark","year":"1998","journal-title":"Infect Immun"},{"key":"ref94","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1084\/jem.183.3.991","article-title":"Interaction of Ipa proteins of Shigella flexneri with alpha5beta1 integrin promotes entry of the bacteria into mammalian cells.","volume":"183","author":"M Watarai","year":"1996","journal-title":"J Exp Med"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/0092-8674(90)90099-Z","article-title":"Multiple beta 1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells.","volume":"60","author":"RR Isberg","year":"1990","journal-title":"Cell"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.chom.2007.06.005","article-title":"Alternative entry receptors for herpes simplex virus and their roles in disease.","volume":"2","author":"JM Taylor","year":"2007","journal-title":"Cell Host Microbe"},{"key":"ref97","article-title":"Infection of neurons and encephalitis after intracranial inoculation of herpes simplex virus requires the entry receptor nectin-1.","author":"SJ Kopp","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref98","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1365-2818.2007.01799.x","article-title":"Comparison of quantitative methods for cell-shape analysis.","volume":"227","author":"Z Pincus","year":"2007","journal-title":"J Microsc"},{"key":"ref99","first-page":"219","article-title":"Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics.","volume":"146","author":"TL Le","year":"1999","journal-title":"J Cell Biol"},{"key":"ref100","first-page":"467","article-title":"Dynamin-dependent endocytosis is necessary for convergent-extension movements in Xenopus animal cap explants.","volume":"46","author":"O Jarrett","year":"2002","journal-title":"Int J Dev Biol"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1038\/ncb1756","article-title":"Modulation of intracellular trafficking regulates cell intercalation in the Drosophila trachea.","volume":"10","author":"DD Shaye","year":"2008","journal-title":"Nat Cell Biol"},{"key":"ref102","article-title":"Endocytosis is required for E-cadherin redistribution at mature adherens junctions.","author":"S de Beco","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref103","doi-asserted-by":"crossref","first-page":"3484","DOI":"10.1091\/mbc.E06-03-0190","article-title":"Endocytosis of cadherin from intracellular junctions is the driving force for cadherin adhesive dimer disassembly.","volume":"17","author":"RB Troyanovsky","year":"2006","journal-title":"Mol Biol Cell"},{"key":"ref104","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.cub.2008.09.029","article-title":"Cdc42, Par6, and aPKC regulate Arp2\/3-mediated endocytosis to control local adherens junction stability.","volume":"18","author":"M Georgiou","year":"2008","journal-title":"Curr Biol"},{"key":"ref105","doi-asserted-by":"crossref","first-page":"21050","DOI":"10.1074\/jbc.M300082200","article-title":"Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin.","volume":"278","author":"AD Paterson","year":"2003","journal-title":"J Biol Chem"},{"key":"ref106","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.micinf.2007.05.004","article-title":"Molecular mechanisms exploited by Listeria monocytogenes during host cell invasion.","volume":"9","author":"S Seveau","year":"2007","journal-title":"Microbes Infect"},{"key":"ref107","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/path.1888","article-title":"Subversion of cellular functions by Listeria monocytogenes.","volume":"208","author":"J Pizarro-Cerda","year":"2006","journal-title":"J Pathol"},{"key":"ref108","doi-asserted-by":"crossref","first-page":"6689","DOI":"10.1128\/JVI.76.13.6689-6700.2002","article-title":"Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway.","volume":"76","author":"NQ Liu","year":"2002","journal-title":"J Virol"},{"key":"ref109","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1038\/emboj.2008.38","article-title":"Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3.","volume":"27","author":"B Amstutz","year":"2008","journal-title":"Embo J"},{"key":"ref110","doi-asserted-by":"crossref","first-page":"4895","DOI":"10.1128\/JVI.02498-08","article-title":"Kaposi&apos;s sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells.","volume":"83","author":"H Raghu","year":"2009","journal-title":"J Virol"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1083\/jcb.200112067","article-title":"Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake.","volume":"158","author":"O Meier","year":"2002","journal-title":"J Cell Biol"},{"key":"ref112","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1128\/IAI.68.3.1696-1699.2000","article-title":"Macropinocytosis as a mechanism of entry into primary human urethral epithelial cells by Neisseria gonorrhoeae.","volume":"68","author":"MK Zenni","year":"2000","journal-title":"Infect Immun"},{"key":"ref113","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1046\/j.1462-5822.2002.00195.x","article-title":"Modulation of Brucella-induced macropinocytosis by lipid rafts mediates intracellular replication.","volume":"4","author":"M Watarai","year":"2002","journal-title":"Cell Microbiol"},{"key":"ref114","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1084\/jem.194.8.1081","article-title":"Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot\/Icm system and the mouse Lgn1 locus.","volume":"194","author":"M Watarai","year":"2001","journal-title":"J Exp Med"},{"key":"ref115","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/nature01603","article-title":"Microbial pathogenesis and cytoskeletal function.","volume":"422","author":"S Gruenheid","year":"2003","journal-title":"Nature"},{"key":"ref116","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1242\/jcs.1989.Supplement_11.8","article-title":"Passage of Salmonella through polarized epithelial cells: role of the host and bacterium.","volume":"Suppl 11","author":"BB Finlay","year":"1989","journal-title":"J Cell Sci"},{"key":"ref117","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1242\/jcs.99.2.283","article-title":"Cytoskeletal rearrangements accompanying salmonella entry into epithelial cells.","volume":"99 (Pt 2)","author":"BB Finlay","year":"1991","journal-title":"J Cell Sci"},{"key":"ref118","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1111\/j.1365-2958.1992.tb01765.x","article-title":"Morphological and cytoskeletal changes in epithelial cells occur immediately upon interaction with Salmonella typhimurium grown under low-oxygen conditions.","volume":"6","author":"CL Francis","year":"1992","journal-title":"Mol Microbiol"},{"key":"ref119","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1002\/j.1460-2075.1995.tb07244.x","article-title":"Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway.","volume":"14","author":"C Dehio","year":"1995","journal-title":"Embo J"},{"key":"ref120","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0882-4010(03)00089-5","article-title":"Internalization of Mycobacterium tuberculosis by macropinocytosis in non-phagocytic cells.","volume":"35","author":"BE Garcia-Perez","year":"2003","journal-title":"Microb Pathog"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.micpath.2008.01.009","article-title":"Internalization of a non-pathogenic mycobacteria by macropinocytosis in human alveolar epithelial A549 cells.","volume":"45","author":"BE Garcia-Perez","year":"2008","journal-title":"Microb Pathog"},{"key":"ref122","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/0092-8674(94)90510-X","article-title":"Contact with epithelial cells induces the formation of surface appendages on Salmonella typhimurium.","volume":"76","author":"CC Ginocchio","year":"1994","journal-title":"Cell"},{"key":"ref123","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.1128\/IAI.67.8.4161-4170.1999","article-title":"Infection of primary human bronchial epithelial cells by Haemophilus influenzae: macropinocytosis as a mechanism of airway epithelial cell entry.","volume":"67","author":"MR Ketterer","year":"1999","journal-title":"Infect Immun"},{"key":"ref124","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/ncb1260","article-title":"CtBP3\/BARS drives membrane fission in dynamin-independent transport pathways.","volume":"7","author":"M Bonazzi","year":"2005","journal-title":"Nat Cell Biol"},{"key":"ref125","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/S0962-8924(00)89101-1","article-title":"Macropinocytosis.","volume":"5","author":"JA Swanson","year":"1995","journal-title":"Trends Cell Biol"},{"key":"ref126","doi-asserted-by":"crossref","first-page":"e1000191","DOI":"10.1371\/journal.pbio.1000191","article-title":"Distinct dynamics of endocytic clathrin-coated pits and coated plaques.","volume":"7","author":"S Saffarian","year":"2009","journal-title":"PLoS Biol"},{"key":"ref127","doi-asserted-by":"crossref","first-page":"e1000394","DOI":"10.1371\/journal.ppat.1000394","article-title":"Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization.","volume":"5","author":"DK Cureton","year":"2009","journal-title":"PLoS Pathog"},{"key":"ref128","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.cell.2007.07.005","article-title":"Listeria InlB takes a different route to met.","volume":"130","author":"E Veiga","year":"2007","journal-title":"Cell"},{"key":"ref129","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/ncb881","article-title":"ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly.","volume":"4","author":"F Palacios","year":"2002","journal-title":"Nat Cell Biol"},{"key":"ref130","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1111\/j.1365-2958.2005.04780.x","article-title":"The 5\u2032 untranslated region-mediated enhancement of intracellular listeriolysin O production is required for Listeria monocytogenes pathogenicity.","volume":"57","author":"A Shen","year":"2005","journal-title":"Mol Microbiol"},{"key":"ref131","doi-asserted-by":"crossref","first-page":"4177","DOI":"10.1128\/JB.184.15.4177-4186.2002","article-title":"Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors.","volume":"184","author":"P Lauer","year":"2002","journal-title":"J Bacteriol"},{"key":"ref132","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.cell.2005.09.020","article-title":"Deconstructing the cadherin-catenin-actin complex.","volume":"123","author":"S Yamada","year":"2005","journal-title":"Cell"},{"key":"ref133","doi-asserted-by":"crossref","first-page":"5014","DOI":"10.1074\/jbc.M705209200","article-title":"Immediate-early signaling induced by E-cadherin engagement and adhesion.","volume":"283","author":"TD Perez","year":"2008","journal-title":"J Biol Chem"},{"key":"ref134","doi-asserted-by":"crossref","first-page":"e1000407","DOI":"10.1371\/journal.ppat.1000407","article-title":"Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche.","volume":"5","author":"S Tan","year":"2009","journal-title":"PLoS Pathog"},{"key":"ref135","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1046\/j.1462-5822.2002.00222.x","article-title":"Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells.","volume":"4","author":"MR Amieva","year":"2002","journal-title":"Cell Microbiol"}],"container-title":["PLoS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1000900","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T18:44:04Z","timestamp":1635360244000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1000900"}},"subtitle":[],"editor":[{"given":"Guy Tran","family":"Van Nhieu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2010,5,13]]},"references-count":135,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2010,5,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1000900","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,13]]}}}