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reductases.","volume":"315","author":"MJ Boulanger","year":"2002","journal-title":"J Mol Biol"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1073\/pnas.95.6.3140","article-title":"Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms.","volume":"95","author":"MC Maiden","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1111\/j.1365-2958.2007.05806.x","article-title":"<italic>Neisseria gonorrhoeae<\/italic> O-linked pilin glycosylation: functional analyses define both the biosynthetic pathway and glycan structure.","volume":"65","author":"FE Aas","year":"2007","journal-title":"Mol Microbiol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"6408","DOI":"10.1093\/emboj\/19.23.6408","article-title":"Components and dynamics of fiber formation define a ubiquitous biogenesis pathway for bacterial 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Evol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1534\/genetics.106.063305","article-title":"Inference of bacterial microevolution using multilocus sequence data.","volume":"175","author":"X Didelot","year":"2007","journal-title":"Genetics"},{"key":"ref75","first-page":"509","article-title":"Use of a non-selective transformation technique to construct a multiply restriction\/modification-deficient mutant of <italic>Neisseria gonorrhoeae<\/italic>.","volume":"251","author":"JS Gunn","year":"1996","journal-title":"Mol Gen Genet"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1365-2958.1995.tb02420.x","article-title":"Characterization of the <italic>pilF-pilD<\/italic> pilus-assembly locus of <italic>Neisseria gonorrhoeae<\/italic>.","volume":"16","author":"NE Freitag","year":"1995","journal-title":"Mol Microbiol"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1006\/abio.1993.1127","article-title":"Detection of <italic>c<\/italic>-type cytochromes using enhanced chemiluminescence.","volume":"209","author":"C Vargas","year":"1993","journal-title":"Anal Biochem"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1042\/BST0340139","article-title":"Organization of the respiratory chain of <italic>Neisseria meningitidis<\/italic>.","volume":"34","author":"M Deeudom","year":"2006","journal-title":"Biochem Soc Trans"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1128\/jb.169.2.790-795.1987","article-title":"Cloning of the <italic>recA<\/italic> gene of <italic>Neisseria gonorrhoeae<\/italic> and construction of gonococcal <italic>recA<\/italic> mutants.","volume":"169","author":"JM Koomey","year":"1987","journal-title":"J 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