{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:49:22Z","timestamp":1778626162214,"version":"3.51.4"},"reference-count":66,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2011,10,6]],"date-time":"2011-10-06T00:00:00Z","timestamp":1317859200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1002279","type":"journal-article","created":{"date-parts":[[2011,10,6]],"date-time":"2011-10-06T21:56:30Z","timestamp":1317938190000},"page":"e1002279","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":26,"title":["Critical Roles for LIGHT and Its Receptors in Generating T Cell-Mediated Immunity during Leishmania donovani Infection"],"prefix":"10.1371","volume":"7","author":[{"given":"Amanda C.","family":"Stanley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"de Labastida Rivera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashraful","family":"Haque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meru","family":"Sheel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona H.","family":"Amante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick T.","family":"Bunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise M.","family":"Randall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Pfeffer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Scheu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Hickey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernadette M.","family":"Saunders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"Ware","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoff R.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Tamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul M.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian R.","family":"Engwerda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2011,10,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0092-8674(01)00237-9","article-title":"The TNF and TNF receptor superfamilies: integrating mammalian biology.","volume":"104","author":"RM Locksley","year":"2001","journal-title":"Cell"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/nri1184","article-title":"Signalling pathways of the TNF superfamily: a double-edged sword.","volume":"3","author":"BB Aggarwal","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1146\/annurev.immunol.23.021704.115719","article-title":"Network communications: lymphotoxins, LIGHT, and TNF.","volume":"23","author":"CF Ware","year":"2005","journal-title":"Annu Rev Immunol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1600-065X.2008.00629.x","article-title":"Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways.","volume":"223","author":"CF Ware","year":"2008","journal-title":"Immunol Rev"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/318665a0","article-title":"Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon.","volume":"318","author":"BB Aggarwal","year":"1985","journal-title":"Nature"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S1074-7613(01)00215-1","article-title":"Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.","volume":"15","author":"SR Ruuls","year":"2001","journal-title":"Immunity"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1074-7613(00)80455-0","article-title":"LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator.","volume":"8","author":"DN Mauri","year":"1998","journal-title":"Immunity"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1126\/science.8171323","article-title":"A lymphotoxin-beta-specific receptor.","volume":"264","author":"PD Crowe","year":"1994","journal-title":"Science"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"27548","DOI":"10.1074\/jbc.273.42.27548","article-title":"Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM\/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth.","volume":"273","author":"JA Harrop","year":"1998","journal-title":"J Biol Chem"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1172\/JCI3492","article-title":"LIGHT, a novel ligand for lymphotoxin beta receptor and TR2\/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer.","volume":"102","author":"Y Zhai","year":"1998","journal-title":"J Clin Invest"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/ni1144","article-title":"B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator.","volume":"6","author":"JR Sedy","year":"2005","journal-title":"Nat Immunol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/ni1554","article-title":"CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator.","volume":"9","author":"G Cai","year":"2008","journal-title":"Nat Immunol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"6083","DOI":"10.1128\/JVI.71.8.6083-6093.1997","article-title":"Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry.","volume":"71","author":"JC Whitbeck","year":"1997","journal-title":"J Virol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1146\/annurev-immunol-030409-101202","article-title":"Slow down and survive: Enigmatic immunoregulation by BTLA and HVEM.","volume":"28","author":"TL Murphy","year":"2010","journal-title":"Annu Rev Immunol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"6244","DOI":"10.1073\/pnas.0902115106","article-title":"Unconventional ligand activation of herpesvirus entry mediator signals cell survival.","volume":"106","author":"TC Cheung","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1182\/blood-2005-09-010629","article-title":"Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes.","volume":"108","author":"K Otterdal","year":"2006","journal-title":"Blood"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1096\/fasebj.12.10.845","article-title":"TR1, a new member of the tumor necrosis factor receptor superfamily, induces fibroblast proliferation and inhibits osteoclastogenesis and bone resorption.","volume":"12","author":"BS Kwon","year":"1998","journal-title":"Faseb J"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"14029","DOI":"10.1074\/jbc.272.22.14029","article-title":"Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1.","volume":"272","author":"SA Marsters","year":"1997","journal-title":"J Biol Chem"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"3288","DOI":"10.4049\/jimmunol.159.7.3288","article-title":"Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.","volume":"159","author":"JL Browning","year":"1997","journal-title":"J Immunol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.immuni.2005.02.007","article-title":"Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells.","volume":"22","author":"K Kabashima","year":"2005","journal-title":"Immunity"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.chom.2007.12.008","article-title":"Lymphotoxin-mediated crosstalk between B cells and splenic stroma promotes the initial type I interferon response to cytomegalovirus.","volume":"3","author":"K Schneider","year":"2008","journal-title":"Cell Host Microbe"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"5210","DOI":"10.4049\/jimmunol.170.10.5210","article-title":"The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes.","volume":"170","author":"S Ehlers","year":"2003","journal-title":"J Immunol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/S0140-6736(05)67629-5","article-title":"Advances in leishmaniasis.","volume":"366","author":"HW Murray","year":"2005","journal-title":"Lancet"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/sj.icb7100011","article-title":"Balancing immunity and pathology in visceral leishmaniasis.","volume":"85","author":"AC Stanley","year":"2007","journal-title":"Immunol Cell Biol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"6289","DOI":"10.1128\/IAI.68.11.6289-6293.2000","article-title":"Visceral leishmaniasis in mice devoid of tumor necrosis factor and response to treatment.","volume":"68","author":"HW Murray","year":"2000","journal-title":"Infect Immun"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1016\/S0002-9440(10)63262-2","article-title":"Distinct roles for lymphotoxin-alpha and tumor necrosis factor in the control of Leishmania donovani infection.","volume":"165","author":"CR Engwerda","year":"2004","journal-title":"Am J Pathol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"768","DOI":"10.4049\/jimmunol.153.2.768","article-title":"Role and effect of TNF-alpha in experimental visceral leishmaniasis.","volume":"153","author":"MC Tumang","year":"1994","journal-title":"J Immunol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0167-5699(99)01549-2","article-title":"Organ-specific immune responses associated with infectious disease.","volume":"21","author":"CR Engwerda","year":"2000","journal-title":"Immunol Today"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.pt.2004.08.009","article-title":"Macrophages, pathology and parasite persistence in experimental visceral leishmaniasis.","volume":"20","author":"CR Engwerda","year":"2004","journal-title":"Trends Parasitol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.0105-2896.2004.00188.x","article-title":"The immunopathology of experimental visceral leishmaniasis.","volume":"201","author":"PM Kaye","year":"2004","journal-title":"Immunol Rev"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0002-9440(10)64199-5","article-title":"A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection.","volume":"161","author":"CR Engwerda","year":"2002","journal-title":"Am J Pathol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1038\/ni861","article-title":"Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis.","volume":"3","author":"M Ato","year":"2002","journal-title":"Nat Immunol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"4244","DOI":"10.4049\/jimmunol.143.12.4244","article-title":"Experimental visceral leishmaniasis: role of endogenous IFN-gamma in host defense and tissue granulomatous response.","volume":"143","author":"KE Squires","year":"1989","journal-title":"J Immunol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1084\/jem.189.4.741","article-title":"Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani.","volume":"189","author":"HW Murray","year":"1999","journal-title":"J Exp Med"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1172\/JCI27083","article-title":"Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis.","volume":"116","author":"S Anand","year":"2006","journal-title":"J Clin Invest"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S1074-7613(02)00423-5","article-title":"The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways.","volume":"17","author":"E Dejardin","year":"2002","journal-title":"Immunity"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"238","DOI":"10.4049\/jimmunol.180.1.238","article-title":"The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells.","volume":"180","author":"C De Trez","year":"2008","journal-title":"J Immunol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/(SICI)1521-4141(199802)28:02<687::AID-IMMU687>3.0.CO;2-N","article-title":"Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection.","volume":"28","author":"PM Gorak","year":"1998","journal-title":"Eur J Immunol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/(SICI)1521-4141(199802)28:02<669::AID-IMMU669>3.0.CO;2-N","article-title":"Neutralization of IL-12 demonstrates the existence of discrete organ- specific phases in the control of Leishmania donovani.","volume":"28","author":"CR Engwerda","year":"1998","journal-title":"Eur J Immunol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1086\/516482","article-title":"Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis.","volume":"175","author":"HW Murray","year":"1997","journal-title":"J Infect Dis"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1146\/annurev.iy.13.040195.001343","article-title":"Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity.","volume":"13","author":"G Trinchieri","year":"1995","journal-title":"Annu Rev Immunol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1128\/IAI.74.1.773-776.2006","article-title":"Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen.","volume":"74","author":"R Polley","year":"2006","journal-title":"Infect Immun"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"3681","DOI":"10.4049\/jimmunol.164.7.3681","article-title":"B cell-deficient mice are highly resistant to Leishmania donovani infection, but develop neutrophil-mediated tissue pathology.","volume":"164","author":"SC Smelt","year":"2000","journal-title":"J Immunol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1084\/jem.167.6.1927","article-title":"The dynamics of granuloma formation in experimental visceral leishmaniasis.","volume":"167","author":"MJ McElrath","year":"1988","journal-title":"J Exp Med"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1002\/1521-4141(200104)31:4<1199::AID-IMMU1199>3.0.CO;2-6","article-title":"CD95 is required for the early control of parasite burden in the liver of Leishmania donovani-infected mice.","volume":"31","author":"CE Alexander","year":"2001","journal-title":"Eur J Immunol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"4105","DOI":"10.4049\/jimmunol.164.8.4105","article-title":"LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response.","volume":"164","author":"K Tamada","year":"2000","journal-title":"J Immunol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/73136","article-title":"Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway.","volume":"6","author":"K Tamada","year":"2000","journal-title":"Nat Med"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1172\/JCI200113827","article-title":"The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT.","volume":"108","author":"J Wang","year":"2001","journal-title":"J Clin Invest"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"6330","DOI":"10.4049\/jimmunol.167.11.6330","article-title":"Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction.","volume":"167","author":"RB Shaikh","year":"2001","journal-title":"J Immunol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/expr.1996.0105","article-title":"An in vivo analysis of cytokine production during Leishmania donovani infection in scid mice.","volume":"84","author":"CR Engwerda","year":"1996","journal-title":"Exp Parasitol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"6901","DOI":"10.4049\/jimmunol.179.10.6901","article-title":"LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major.","volume":"179","author":"G Xu","year":"2007","journal-title":"J Immunol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"7458","DOI":"10.4049\/jimmunol.181.11.7458","article-title":"Cutting edge: selective blockade of LIGHT-lymphotoxin beta receptor signaling protects mice from experimental cerebral malaria caused by Plasmodium berghei ANKA.","volume":"181","author":"LM Randall","year":"2008","journal-title":"J Immunol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1084\/jem.187.4.601","article-title":"Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice.","volume":"187","author":"B Lu","year":"1998","journal-title":"J Exp Med"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/icb.2008.19","article-title":"Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T-cell responses.","volume":"86","author":"F Geissmann","year":"2008","journal-title":"Immunol Cell Biol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.cell.2010.09.039","article-title":"Microbial stimulation fully differentiates monocytes to DC-SIGN\/CD209(+) dendritic cells for immune T cell areas.","volume":"143","author":"C Cheong","year":"2010","journal-title":"Cell"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(92)90030-G","article-title":"RAG-1-deficient mice have no mature B and T lymphocytes.","volume":"68","author":"P Mombaerts","year":"1992","journal-title":"Cell"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1084\/jem.20020215","article-title":"Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis.","volume":"195","author":"S Scheu","year":"2002","journal-title":"J Exp Med"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1002\/eji.1830271020","article-title":"Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue.","volume":"27","author":"H Korner","year":"1997","journal-title":"Eur J Immunol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1046\/j.1440-1711.1998.00709.x","article-title":"Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements.","volume":"76","author":"MJ Barnden","year":"1998","journal-title":"Immunol Cell Biol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0092-8674(94)90169-4","article-title":"T cell receptor antagonist peptides induce positive selection.","volume":"76","author":"KA Hogquist","year":"1994","journal-title":"Cell"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1126\/science.8456300","article-title":"Multiple defects of immune cell function in mice with disrupted interferon-gamma genes.","volume":"259","author":"DK Dalton","year":"1993","journal-title":"Science"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1126\/science.278.5343.1623","article-title":"Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors.","volume":"278","author":"J Cui","year":"1997","journal-title":"Science"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"e1000158","DOI":"10.1371\/journal.ppat.1000158","article-title":"VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis.","volume":"4","author":"AC Stanley","year":"2008","journal-title":"PLoS Pathog"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.4049\/jimmunol.0903080","article-title":"Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity.","volume":"184","author":"A Haque","year":"2010","journal-title":"J Immunol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"e1000028","DOI":"10.1371\/journal.ppat.1000028","article-title":"Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis.","volume":"4","author":"AC Stanley","year":"2008","journal-title":"PLoS Pathog"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"17148","DOI":"10.1074\/jbc.M110.105874","article-title":"Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor.","volume":"285","author":"H Sanjo","year":"2010","journal-title":"J Biol Chem"}],"container-title":["PLoS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1002279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T10:24:12Z","timestamp":1713003852000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1002279"}},"subtitle":[],"editor":[{"given":"David L.","family":"Sacks","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2011,10,6]]},"references-count":66,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2011,10,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1002279","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,6]]}}}