{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:08:06Z","timestamp":1791644886957,"version":"4.3.4"},"reference-count":78,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T00:00:00Z","timestamp":1337212800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1002713","type":"journal-article","created":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T21:02:41Z","timestamp":1337288561000},"page":"e1002713","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":150,"title":["Extracellular Superoxide Dismutase Protects Histoplasma Yeast Cells from Host-Derived Oxidative Stress"],"prefix":"10.1371","volume":"8","author":[{"given":"Brian H.","family":"Youseff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric D.","family":"Holbrook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Smolnycki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad A.","family":"Rappleye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2012,5,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev.micro.57.030502.090938","article-title":"Pathways of oxidative damage.","volume":"57","author":"JA Imlay","year":"2003","journal-title":"Annu Rev Microbiol"},{"key":"ref2","first-page":"2927","article-title":"Molecular basis for the enhanced respiratory burst of activated macrophages.","volume":"44","author":"RB Johnston Jr","year":"1985","journal-title":"Fed Proc"},{"key":"ref3","first-page":"1619","article-title":"Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma.","volume":"134","author":"HW Murray","year":"1985","journal-title":"J Immunol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"437","DOI":"10.2307\/4594192","article-title":"The medical mycological iceberg.","volume":"86","author":"L Ajello","year":"1971","journal-title":"HSMHA Health Rep"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/infdis\/161.1.143","article-title":"The intracellular fate of <italic>Histoplasma capsulatum<\/italic> in human macrophages is unaffected by recombinant human interferon-gamma.","volume":"161","author":"J Fleischmann","year":"1990","journal-title":"J Infect Dis"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1365-2249.1995.tb06637.x","article-title":"Antifungal mechanisms of activated murine bronchoalveolar or peritoneal macrophages for <italic>Histoplasma capsulatum<\/italic>.","volume":"102","author":"E Brummer","year":"1995","journal-title":"Clin Exp Immunol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1172\/JCI114416","article-title":"Phagocytosis of <italic>Histoplasma capsulatum<\/italic> yeasts and microconidia by human cultured macrophages and alveolar macrophages. Cellular cytoskeleton requirement for attachment and ingestion.","volume":"85","author":"SL Newman","year":"1990","journal-title":"J Clin Invest"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1513\/pats.200907-069AL","article-title":"Histoplasmosis.","volume":"7","author":"KS Knox","year":"2010","journal-title":"Proc Am Thorac Soc"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s11908-001-0031-6","article-title":"Pulmonary histoplasmosis.","volume":"3","author":"CA Kauffman","year":"2001","journal-title":"Curr Infect Dis Rep"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1128\/IAI.55.1.29-34.1987","article-title":"<italic>Histoplasma capsulatum<\/italic> fails to trigger release of superoxide from macrophages.","volume":"55","author":"LG Eissenberg","year":"1987","journal-title":"Infect Immun"},{"key":"ref11","first-page":"582","article-title":"Modulation of the macrophage oxidative burst by <italic>Histoplasma capsulatum<\/italic>.","volume":"138","author":"JE Wolf","year":"1987","journal-title":"J Immunol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1128\/IAI.58.5.1296-1300.1990","article-title":"In vivo activation of macrophage oxidative burst activity by cytokines and amphotericin B.","volume":"58","author":"JE Wolf","year":"1990","journal-title":"Infect Immun"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1128\/IAI.57.2.513-519.1989","article-title":"Effects of <italic>Histoplasma capsulatum<\/italic> on murine macrophage functions: inhibition of macrophage priming, oxidative burst, and antifungal activities.","volume":"57","author":"JE Wolf","year":"1989","journal-title":"Infect Immun"},{"key":"ref14","first-page":"771","article-title":"The pathogenesis of experimental pulmonary histoplasmosis. Correlative studies of histopathology, bronchoalveolar lavage, and respiratory function.","volume":"134","author":"RP Baughman","year":"1986","journal-title":"Am Rev Respir Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1189\/jlb.0308154","article-title":"<italic>Histoplasma capsulatum<\/italic> manifests preferential invasion of phagocytic subpopulations in murine lungs.","volume":"84","author":"GS Deepe Jr","year":"2008","journal-title":"J Leukocyte Biol"},{"key":"ref16","first-page":"4765","article-title":"The respiratory burst response to <italic>Histoplasma capsulatum<\/italic> by human neutrophils. Evidence for intracellular trapping of superoxide anion.","volume":"144","author":"RA Schnur","year":"1990","journal-title":"J Immunol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/02681219180000241","article-title":"Antifungal activity of murine polymorphonuclear neutrophils against <italic>Histoplasma capsulatum<\/italic>.","volume":"29","author":"N Kurita","year":"1991","journal-title":"J Med Vet Mycol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00462229","article-title":"Resistance of <italic>Histoplasma capsulatum<\/italic> to killing by human neutrophils. Evasion of oxidative burst and lysosomal-fusion products.","volume":"115","author":"N Kurita","year":"1991","journal-title":"Mycopathologia"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1172\/JCI112603","article-title":"In vitro susceptibility of fungi to killing by neutrophil granulocytes discriminates between primary pathogenicity and opportunism.","volume":"78","author":"A Schaffner","year":"1986","journal-title":"J Clin Invest"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/infdis\/164.1.158","article-title":"Fungistatic activity of human neutrophils against <italic>Histoplasma capsulatum<\/italic>: correlation with phagocytosis.","volume":"164","author":"E Brummer","year":"1991","journal-title":"J Infect Dis"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1021\/pr1011697","article-title":"Definition of the extracellular proteome of pathogenic-phase <italic>Histoplasma capsulatum<\/italic>.","volume":"10","author":"ED Holbrook","year":"2011","journal-title":"J Proteome Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1126\/science.290.5495.1368","article-title":"Intracellular parasitism by <italic>Histoplasma capsulatum<\/italic>: fungal virulence and calcium dependence.","volume":"290","author":"TS Sebghati","year":"2000","journal-title":"Science"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0009-8981(99)00246-6","article-title":"A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1).","volume":"293","author":"AV Peskin","year":"2000","journal-title":"Clin Chim Acta"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.fgb.2005.04.002","article-title":"Features and functions of covalently linked proteins in fungal cell walls.","volume":"42","author":"PW De Groot","year":"2005","journal-title":"Fungal Genet Biol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.bbalip.2006.05.015","article-title":"Biosynthesis and function of GPI proteins in the yeast <italic>Saccharomyces cerevisiae<\/italic>.","volume":"1771","author":"M Pittet","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1128\/EC.00214-10","article-title":"The yeast-phase virulence requirement for alpha-glucan synthase differs among <italic>Histoplasma capsulatum<\/italic> chemotypes.","volume":"10","author":"JA Edwards","year":"2011","journal-title":"Eukaryot Cell"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1289\/ehp.845537","article-title":"Paraquat: model for oxidant-initiated toxicity.","volume":"55","author":"JS Bus","year":"1984","journal-title":"Environ Health Perspect"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1074\/jbc.M708597200","article-title":"Complex I is the major site of mitochondrial superoxide production by paraquat.","volume":"283","author":"HM Cocheme","year":"2008","journal-title":"J Biol Chem"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0022-1759(90)90357-2","article-title":"The use of diphenylene iodonium, an inhibitor of NADPH oxidase, to investigate the antimicrobial action of human monocyte derived macrophages.","volume":"133","author":"AK Robertson","year":"1990","journal-title":"J Immunol Methods"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1042\/bj2510887","article-title":"The effect of the NADPH oxidase inhibitor diphenyleneiodonium on aerobic and anaerobic microbicidal activities of human neutrophils.","volume":"251","author":"JA Ellis","year":"1988","journal-title":"Biochem J"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1084\/jem.182.3.751","article-title":"The p47phox mouse knock-out model of chronic granulomatous disease.","volume":"182","author":"SH Jackson","year":"1995","journal-title":"J Exp Med"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"5668","DOI":"10.1128\/IAI.68.10.5668-5672.2000","article-title":"Identification of constituents of human neutrophil azurophil granules that mediate fungistasis against <italic>Histoplasma capsulatum<\/italic>.","volume":"68","author":"SL Newman","year":"2000","journal-title":"Infect Immun"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1128\/IAI.62.6.2375-2378.1994","article-title":"Inhibition of intracellular <italic>Histoplasma capsulatum<\/italic> replication by murine macrophages that produce human defensin.","volume":"62","author":"MA Couto","year":"1994","journal-title":"Infect Immun"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1128\/IAI.62.5.1940-1945.1994","article-title":"Antihistoplasma effect of activated mouse splenic macrophages involves production of reactive nitrogen intermediates.","volume":"62","author":"TE Lane","year":"1994","journal-title":"Infect Immun"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0022-1759(00)00156-3","article-title":"Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: a simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents.","volume":"238","author":"AS Tan","year":"2000","journal-title":"J Immunol Methods"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1080\/02681219080000601","article-title":"Evidence that the M antigen of <italic>Histoplasma capsulatum<\/italic> var. <italic>capsulatum<\/italic> is a catalase which exhibits cross-reactivity with other dimorphic fungi.","volume":"28","author":"AJ Hamilton","year":"1990","journal-title":"J Med Vet Mycol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"e3449","DOI":"10.1371\/journal.pone.0003449","article-title":"Biological function and molecular mapping of M antigen in yeast phase of <italic>Histoplasma capsulatum<\/italic>.","volume":"3","author":"AJ Guimaraes","year":"2008","journal-title":"PloS One"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1099\/00221287-148-4-1129","article-title":"Redundancy, phylogeny and differential expression of <italic>Histoplasma capsulatum<\/italic> catalases.","volume":"148","author":"CH Johnson","year":"2002","journal-title":"Microbiology"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"4980","DOI":"10.1128\/IAI.69.8.4980-4987.2001","article-title":"Cu,Zn superoxide dismutase of <italic>Mycobacterium tuberculosis<\/italic> contributes to survival in activated macrophages that are generating an oxidative burst.","volume":"69","author":"DL Piddington","year":"2001","journal-title":"Infect Immun"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"13997","DOI":"10.1073\/pnas.94.25.13997","article-title":"Periplasmic superoxide dismutase protects <italic>Salmonella<\/italic> from products of phagocyte NADPH-oxidase and nitric oxide synthase.","volume":"94","author":"MA De Groote","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"7502","DOI":"10.1073\/pnas.96.13.7502","article-title":"Virulent <italic>Salmonella typhimurium<\/italic> has two periplasmic Cu, Zn-superoxide dismutases.","volume":"96","author":"FC Fang","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"6447","DOI":"10.1128\/JB.00534-09","article-title":"Identification of <italic>Francisella tularensis<\/italic> live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species.","volume":"191","author":"AA Melillo","year":"2009","journal-title":"J Bacteriol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1128\/EC.4.1.46-54.2005","article-title":"<italic>Cryptococcus neoformans<\/italic> mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth.","volume":"4","author":"SS Giles","year":"2005","journal-title":"Eukaryot Cell"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1046\/j.1365-2958.2003.03393.x","article-title":"Characterization of Cu,Zn superoxide dismutase (<italic>SOD1<\/italic>) gene knock-out mutant of <italic>Cryptococcus neoformans<\/italic> var. <italic>gattii<\/italic>: role in biology and virulence.","volume":"47","author":"SD Narasipura","year":"2003","journal-title":"Mol Microbiol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1111\/j.1365-2958.2005.04503.x","article-title":"Characterization of <italic>Cryptococcus neoformans<\/italic> variety <italic>gattii SOD2<\/italic> reveals distinct roles of the two superoxide dismutases in fungal biology and virulence.","volume":"55","author":"SD Narasipura","year":"2005","journal-title":"Mol Microbiol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"3705","DOI":"10.1099\/00221287-148-11-3705","article-title":"Copper- and zinc-containing superoxide dismutase (Cu\/ZnSOD) is required for the protection of <italic>Candida albicans<\/italic> against oxidative stresses and the expression of its full virulence.","volume":"148","author":"CS Hwang","year":"2002","journal-title":"Microbiology"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1128\/IAI.71.1.173-180.2003","article-title":"Superoxide dismutase influences the virulence of <italic>Cryptococcus neoformans<\/italic> by affecting growth within macrophages.","volume":"71","author":"GM Cox","year":"2003","journal-title":"Infect Immun"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00294-010-0298-y","article-title":"Characterization of a CuZn superoxide dismutase gene in the arbuscular mycorrhizal fungus <italic>Glomus intraradices<\/italic>.","volume":"56","author":"M Gonzalez-Guerrero","year":"2010","journal-title":"Curr Genet"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1104\/pp.104.050435","article-title":"The mycorrhizal fungus <italic>Gigaspora margarita<\/italic> possesses a CuZn superoxide dismutase that is up-regulated during symbiosis with legume hosts.","volume":"137","author":"L Lanfranco","year":"2005","journal-title":"Plant Physiol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1094\/MPMI-22-8-0942","article-title":"The YAP1 homolog-mediated oxidative stress tolerance is crucial for pathogenicity of the necrotrophic fungus <italic>Alternaria alternata<\/italic> in citrus.","volume":"22","author":"CH Lin","year":"2009","journal-title":"Mol Plant Microbe Interact"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1094\/MPMI-02-11-0028","article-title":"High levels of a fungal superoxide dismutase and increased concentration of a PR-10 plant protein in associations between the endophytic fungus <italic>Neotyphodium lolii<\/italic> and ryegrass.","volume":"24","author":"N Zhang","year":"2011","journal-title":"Mol Plant Microbe Interact"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1094\/PHYTO-98-12-1334","article-title":"RNA-mediated gene silencing of superoxide dismutase (bcsod1) in <italic>Botrytis cinerea<\/italic>.","volume":"98","author":"RM Patel","year":"2008","journal-title":"Phytopathology"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1364-3703.2004.00201.x","article-title":"Functional analysis of H(2)O(2)-generating systems in <italic>Botrytis cinerea<\/italic>: the major Cu-Zn-superoxide dismutase (BCSOD1) contributes to virulence on French bean, whereas a glucose oxidase (BCGOD1) is dispensable.","volume":"5","author":"Y Rolke","year":"2004","journal-title":"Mol Plant Pathol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1365-2958.2005.04557.x","article-title":"Granulocytes govern the transcriptional response, morphology and proliferation of <italic>Candida albicans<\/italic> in human blood.","volume":"56","author":"C Fradin","year":"2005","journal-title":"Mol Microbiol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1091\/mbc.E03-03-0179","article-title":"Superoxide dismutases in <italic>Candida albicans<\/italic>: transcriptional regulation and functional characterization of the hyphal-induced <italic>SOD5<\/italic> gene.","volume":"15","author":"M Martchenko","year":"2004","journal-title":"Mol Biol Cell"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1365-2958.2008.06528.x","article-title":"<italic>Candida albicans<\/italic> cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance.","volume":"71","author":"IE Frohner","year":"2009","journal-title":"Mol Microbiol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"4033","DOI":"10.1128\/AAC.00280-11","article-title":"Superoxide dismutases are involved in <italic>Candida albicans<\/italic> biofilm persistence against miconazole.","volume":"55","author":"A Bink","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1073\/pnas.0609848104","article-title":"<italic>Histoplasma capsulatum<\/italic> alpha-(1,3)-glucan blocks innate immune recognition by the beta-glucan receptor.","volume":"104","author":"CA Rappleye","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1172\/JCI27114","article-title":"Immune sensing of <italic>Candida albicans<\/italic> requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors.","volume":"116","author":"MG Netea","year":"2006","journal-title":"J Clin Invest"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.micinf.2009.03.010","article-title":"Dectin-1 is required for human dendritic cells to initiate immune response to <italic>Candida albicans<\/italic> through Syk activation.","volume":"11","author":"F Skrzypek","year":"2009","journal-title":"Microbes Infect"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1182\/blood-2005-03-1239","article-title":"Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production.","volume":"106","author":"DM Underhill","year":"2005","journal-title":"Blood"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1038\/sj.emboj.7600594","article-title":"Dectin-1 mediates macrophage recognition of <italic>Candida albicans<\/italic> yeast but not filaments.","volume":"24","author":"BN Gantner","year":"2005","journal-title":"EMBO J"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/eji.200636653","article-title":"Dectin-1 promotes fungicidal activity of human neutrophils.","volume":"37","author":"AD Kennedy","year":"2007","journal-title":"Eur J Immunol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1099\/00222615-35-1-29","article-title":"Killing of <italic>Histoplasma capsulatum<\/italic> by gamma-interferon-activated human monocyte-derived macrophages: evidence for a superoxide anion-dependent mechanism.","volume":"35","author":"E Brummer","year":"1991","journal-title":"J Med Microbiol"},{"key":"ref65","first-page":"2407","article-title":"Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.","volume":"141","author":"AH Ding","year":"1988","journal-title":"J Immunol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1099\/00222615-43-3-224","article-title":"Killing of <italic>Histoplasma capsulatum<\/italic> by macrophage colony stimulating factor-treated human monocyte-derived macrophages: role for reactive oxygen intermediates.","volume":"43","author":"G Desai","year":"1995","journal-title":"J Med Microbiol"},{"key":"ref67","first-page":"2593","article-title":"Inhibition of growth of <italic>Histoplasma capsulatum<\/italic> by lymphokine-stimulated macrophages.","volume":"132","author":"B Wu-Hsieh","year":"1984","journal-title":"J Immunol"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1128\/IAI.55.4.1014-1016.1987","article-title":"Inhibition of the intracellular growth of <italic>Histoplasma capsulatum<\/italic> by recombinant murine gamma interferon.","volume":"55","author":"BA Wu-Hsieh","year":"1987","journal-title":"Infect Immun"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1128\/IAI.66.4.1473-1481.1998","article-title":"Evolution of the primary immune response to <italic>Histoplasma capsulatum<\/italic> in murine lung.","volume":"66","author":"JA Cain","year":"1998","journal-title":"Infect Immun"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/02681218880000211","article-title":"Quantitative plating of <italic>Histoplasma capsulatum<\/italic> without addition of conditioned medium or siderophores.","volume":"26","author":"PL Worsham","year":"1988","journal-title":"J Med Vet Mycol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1128\/IAI.66.4.1697-1707.1998","article-title":"Electrotransformation and expression of bacterial genes encoding hygromycin phosphotransferase and beta-galactosidase in the pathogenic fungus <italic>Histoplasma capsulatum<\/italic>.","volume":"66","author":"JP Woods","year":"1998","journal-title":"Infect Immun"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"3211","DOI":"10.1128\/JB.183.10.3211-3223.2001","article-title":"<italic>CAP1<\/italic>, an adenylate cyclase-associated protein gene, regulates bud-hypha transitions, filamentous growth, and cyclic AMP levels and is required for virulence of <italic>Candida albicans<\/italic>.","volume":"183","author":"YS Bahn","year":"2001","journal-title":"J Bacteriol"},{"key":"ref73","article-title":"RNAi-based gene silencing using a GFP sentinel system in <italic>Histoplasma capsulatum<\/italic>.","author":"BH Youseff","year":"2012"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0021-9258(19)50881-X","article-title":"A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase.","volume":"195","author":"RF Beers Jr","year":"1952","journal-title":"J Biol Chem"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1248\/bpb.23.1382","article-title":"A simple method for isolating human and rabbit polymorphonuclear neutrophils (PMNs).","volume":"23","author":"F Kouoh","year":"2000","journal-title":"Biol Pharm Bull"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-1-59745-467-4_2","article-title":"Isolation of human neutrophils from venous blood.","volume":"412","author":"WM Nauseef","year":"2007","journal-title":"Methods Mol Biol"},{"key":"ref77","first-page":"Unit 14 11","article-title":"The isolation and characterization of murine macrophages.","volume":"Chapter 14","author":"X Zhang","year":"2008","journal-title":"Curr Protoc Immunol"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1111\/j.1365-2958.2006.05436.x","article-title":"An alpha-(1,4)-amylase is essential for alpha-(1,3)-glucan production and virulence in <italic>Histoplasma capsulatum<\/italic>.","volume":"62","author":"CL Marion","year":"2006","journal-title":"Mol Microbiol"}],"container-title":["PLoS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1002713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T21:38:37Z","timestamp":1642282717000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1002713"}},"subtitle":[],"editor":[{"given":"Alex","family":"Andrianopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2012,5,17]]},"references-count":78,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2012,5,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1002713","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,17]]}}}