{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:23:08Z","timestamp":1792581788179,"version":"4.5.0"},"reference-count":97,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2014,8,7]],"date-time":"2014-08-07T00:00:00Z","timestamp":1407369600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1004301","type":"journal-article","created":{"date-parts":[[2014,8,7]],"date-time":"2014-08-07T18:32:46Z","timestamp":1407436366000},"page":"e1004301","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":98,"title":["Cyclic di-GMP-dependent Signaling Pathways in the Pathogenic Firmicute Listeria monocytogenes"],"prefix":"10.1371","volume":"10","author":[{"given":"Li-Hong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkan K.","family":"K\u00f6seo\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zehra T.","family":"G\u00fcvener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Myers-Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E. F.","family":"D'Orazio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt W.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Gomelsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,8,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/325279a0","article-title":"Regulation of cellulose synthesis in <italic>Acetobacter xylinum<\/italic> by cyclic diguanylic acid","volume":"325","author":"P Ross","year":"1987","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.00043-12","article-title":"Cyclic di-GMP: The first 25 years of a universal bacterial second messenger","volume":"77","author":"U R\u00f6mling","year":"2013","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1002\/pro.2093","article-title":"Sensing the messenger: The diverse ways that bacteria signal through c-di-GMP","volume":"21","author":"PV Krasteva","year":"2012","journal-title":"Protein Sci"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.mib.2011.12.008","article-title":"You&apos;ve come a long way: c-di-GMP signaling","volume":"15","author":"H Sondermann","year":"2012","journal-title":"Curr Opin Microbiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev-cellbio-101011-155705","article-title":"Second messenger regulation of biofilm formation: breakthroughs in understanding c-di-GMP effector systems","volume":"28","author":"CD Boyd","year":"2012","journal-title":"Annu Rev Cell Dev Biol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1111\/j.1462-5822.2011.01619.x","article-title":"The bacterial second messenger c-di-GMP: mechanisms of signalling","volume":"13","author":"E Mills","year":"2011","journal-title":"Cell Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1146\/annurev.micro.61.080706.093426","article-title":"Roles of cyclic diguanylate in the regulation of bacterial pathogenesis","volume":"61","author":"R Tamayo","year":"2007","journal-title":"Annu Rev Microbiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1073\/pnas.0511090103","article-title":"Analysis of <italic>Pseudomonas aeruginosa<\/italic> diguanylate cyclases and phosphodiesterases reveals a role for bis-(3\u2032-5\u2032)-cyclic-GMP in virulence","volume":"103","author":"H Kulesekara","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"e28351","DOI":"10.1371\/journal.pone.0028351","article-title":"Complex c-di-GMP signaling networks mediate transition between virulence properties and biofilm formation in <italic>Salmonella enterica<\/italic> serovar Typhimurium","volume":"6","author":"I Ahmad","year":"2011","journal-title":"PLoS One"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"3492","DOI":"10.1128\/JB.00119-09","article-title":"<italic>Pseudomonas aeruginosa<\/italic> rugose small colony variants have adaptations likely to promote persistence in the cystic fibrosis lung","volume":"191","author":"M Starkey","year":"2009","journal-title":"J Bacteriol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"e1000804","DOI":"10.1371\/journal.ppat.1000804","article-title":"YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in <italic>Pseudomonas aeruginosa<\/italic>","volume":"6","author":"JG Malone","year":"2010","journal-title":"PLoS Pathog"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1128\/IAI.00057-11","article-title":"Direct evaluation of <italic>Pseudomonas aeruginosa<\/italic> biofilm mediators in a chronic infection model","volume":"79","author":"MS Byrd","year":"2011","journal-title":"Infect Immun"},{"key":"ref13","first-page":"693","article-title":"<italic>Anaplasma phagocytophilum<\/italic> PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic di-GMP in host-cell infection","volume":"191","author":"TH Lai","year":"2008","journal-title":"J Bacteriol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"4122","DOI":"10.1128\/JB.00132-10","article-title":"Cyclic di-GMP signaling regulates invasion by <italic>Ehrlichia chaffeensis<\/italic> of human monocytes","volume":"192","author":"Y Kumagai","year":"2010","journal-title":"J Bacteriol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.1128\/IAI.05320-11","article-title":"c-di-GMP signaling regulates intracellular aggregation, sessility, and growth of <italic>Ehrlichia chaffeensis<\/italic>","volume":"79","author":"Y Kumagai","year":"2011","journal-title":"Infect Immun"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"e00316","DOI":"10.1128\/mBio.00316-10","article-title":"Cyclic diguanylate signaling proteins control intracellular growth of <italic>Legionella pneumophila<\/italic>","volume":"2","author":"A Levi","year":"2011","journal-title":"mBio"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"19484","DOI":"10.1073\/pnas.1112371108","article-title":"Illuminating the landscape of host-pathogen interactions with the bacterium <italic>Listeria monocytogenes<\/italic>","volume":"108","author":"P Cossart","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrmicro2171","article-title":"<italic>Listeria monocytogenes<\/italic> - from saprophyte to intracellular pathogen","volume":"7","author":"NE Freitag","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1574-695X.2008.00404.x","article-title":"<italic>Listeria monocytogenes<\/italic>: epidemiology, human disease, and mechanisms of brain invasion","volume":"53","author":"DA Drevets","year":"2008","journal-title":"FEMS Immunoi Med Microbiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1469-0691.2009.03109.x","article-title":"Listeriosis: a resurgent foodborne infection","volume":"16","author":"F Allerberger","year":"2010","journal-title":"Clin Microbiol Infection"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1017\/S1479050504001322","article-title":"<italic>Listeria monocytogenes<\/italic>: biofilm formation and persistence in food-processing environments","volume":"1","author":"T Moretro","year":"2004","journal-title":"Biofilms"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1186\/1471-2164-9-539","article-title":"Short-term genome evolution of <italic>Listeria monocytogenes<\/italic> in a non-controlled environment","volume":"9","author":"RH Orsi","year":"2008","journal-title":"BMC Genomics"},{"key":"ref23","unstructured":"Centers for Disease Control and Prevention. Multistate Outbreak of Listeriosis Linked to Whole Cantaloupes from Jensen Farms, Colorado. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.cdc.gov\/listeria\/outbreaks\/cantaloupes-jensen-farms\/082712\/index.html\" xlink:type=\"simple\">http:\/\/www.cdc.gov\/listeria\/outbreaks\/cantaloupes-jensen-farms\/082712\/index.html<\/ext-link>"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1056\/NEJMoa1215837","article-title":"Multistate outbreak of listeriosis associated with cantaloupe","volume":"369","author":"JT McCollum","year":"2013","journal-title":"N Engl J Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.mib.2004.10.014","article-title":"Biofilm formation in plant-microbe associations","volume":"7","author":"BE Ramey","year":"2004","journal-title":"Curr Opin Microbiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrmicro2415","article-title":"The biofilm matrix","volume":"8","author":"HC Flemming","year":"2010","journal-title":"Nat Rev Microbiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/j.1462-2920.2010.02378.x","article-title":"Molecular biology of surface colonization by <italic>Listeria monocytogenes<\/italic>: an additional facet of an opportunistic Gram-positive foodborne pathogen","volume":"13","author":"S Renier","year":"2011","journal-title":"Environ Microbiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1089\/fpd.2011.1087","article-title":"<italic>Listeria monocytogenes<\/italic> growth dynamics on produce: A review of the available data for predictive modeling","volume":"9","author":"K Hoelzer","year":"2012","journal-title":"Foodborne Pathog Dis"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"e1002039","DOI":"10.1371\/journal.pgen.1002039","article-title":"c-di-GMP turn-over in <italic>Clostridium difficile<\/italic> is controlled by a plethora of diguanylate cyclases and phosphodiesterases","volume":"7","author":"E Bordeleau","year":"2011","journal-title":"PLoS Genet"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.1128\/JB.00100-12","article-title":"Cyclic diguanylate inversely regulates motility and aggregation in <italic>Clostridium difficile<\/italic>","volume":"194","author":"EB Purcell","year":"2012","journal-title":"J Bacteriol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"5080","DOI":"10.1128\/JB.01092-12","article-title":"Evidence for cyclic di-GMP-mediated signaling in <italic>Bacillus subtilis<\/italic>","volume":"194","author":"Y Chen","year":"2012","journal-title":"J Bacteriol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"4782","DOI":"10.1128\/JB.00373-13","article-title":"Functional characterization of core components of the <italic>Bacillus subtilis<\/italic> c-di-GMP signaling pathway","volume":"195","author":"X Gao","year":"2013","journal-title":"J Bacteriol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"5178","DOI":"10.1128\/JB.00375-08","article-title":"A staphylococcal GGDEF domain protein regulates biofilm formation independently of c-di-GMP","volume":"190","author":"LM Holland","year":"2008","journal-title":"J Bacteriol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1126\/science.1159519","article-title":"Riboswitches in eubacteria sense the second messenger cyclic di-GMP","volume":"321","author":"N Sudarsan","year":"2008","journal-title":"Science"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1126\/science.1190713","article-title":"An allosteric self-splicing ribozyme triggered by a bacterial second messenger","volume":"329","author":"ER Lee","year":"2010","journal-title":"Science"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1101\/gad.289504","article-title":"Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel diguanylate cyclase output domain","volume":"18","author":"R Paul","year":"2004","journal-title":"Genes Dev"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1128\/JB.187.5.1792-1798.2005","article-title":"Cyclic diguanylate is a ubiquitous signaling molecule in bacteria: Insights into the biochemistry of the GGDEF protein domain","volume":"187","author":"DA Ryjenkov","year":"2005","journal-title":"J Bacteriol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"4774","DOI":"10.1128\/JB.187.14.4774-4781.2005","article-title":"The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains","volume":"187","author":"AJ Schmidt","year":"2005","journal-title":"J Bacteriol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"30829","DOI":"10.1074\/jbc.M504429200","article-title":"Identification and characterization of a cyclic di-GMP-specific phosphodiesterase and its allosteric control by GTP","volume":"280","author":"M Christen","year":"2005","journal-title":"J Biol Chem"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"33324","DOI":"10.1074\/jbc.M506500200","article-title":"The EAL domain protein VieA is a cyclic diguanylate phosphodiesterase","volume":"280","author":"R Tamayo","year":"2005","journal-title":"J Biol Chem"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"6712","DOI":"10.1073\/pnas.0600345103","article-title":"Cell-cell signaling in <italic>Xanthomonas campestris<\/italic> involves an HD-GYP domain protein that functions in cyclic di-GMP turnover","volume":"103","author":"RP Ryan","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref42","doi-asserted-by":"crossref","unstructured":"Punta M, Coggill PC, Eberhardt RY, Mistry J, Tate J, <etal>et al<\/etal>. (2012) The Pfam protein families database. Nucleic Acids Res 40(Database issue): D290\u2013301.","DOI":"10.1093\/nar\/gkr1065"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"17084","DOI":"10.1073\/pnas.0406134101","article-title":"Structural basis of activity and allosteric control of diguanylate cyclase","volume":"101","author":"C Chan","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1038\/nature07966","article-title":"Structure and mechanism of a bacterial ligh-regulated cyclic nucleotide phosphodiesterase","volume":"459","author":"TR Barends","year":"2009","journal-title":"Nature"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/nature08080","article-title":"The <italic>Listeria<\/italic> transcriptional landscape from saprophytism to virulence","volume":"459","author":"A Toledo-Arana","year":"2009","journal-title":"Nature"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1006\/jmbi.2001.5080","article-title":"Assignment of homology to genome sequences using a library of Hidden Markov Models that represent all proteins of known structure","volume":"313","author":"J Gough","year":"2001","journal-title":"J Mol Biol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"32015","DOI":"10.1074\/jbc.M603589200","article-title":"Allosteric control of cyclic di-GMP signaling","volume":"281","author":"B Christen","year":"2006","journal-title":"J Biol Chem"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1111\/j.1365-2958.2007.05879.x","article-title":"A cyclic-di-GMP receptor required for bacterial exopolysaccharide production","volume":"65","author":"VT Lee","year":"2007","journal-title":"Mol Microbiol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1101\/gad.502409","article-title":"Second messenger-mediated spatiotemporal control of protein degradation regulates bacterial cell cycle progression","volume":"23","author":"A Duerig","year":"2009","journal-title":"Genes Dev"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1111\/j.1365-2958.2004.04206.x","article-title":"GGDEF and EAL domains inversely regulate cyclic di-GMP levels and transition from sessility to motility","volume":"53","author":"R Simm","year":"2004","journal-title":"Mol Microbiol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"30310","DOI":"10.1074\/jbc.C600179200","article-title":"The PilZ domain is a receptor for the second messenger c-di-GMP: The PilZ domain protein YcgR controls motility in entrobacteria","volume":"281","author":"DA Ryjenkov","year":"2006","journal-title":"J Biol Chem"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1371\/journal.pgen.0030154","article-title":"A comprehensive genetic characterization of bacterial motility","volume":"3","author":"HS Girgis","year":"2007","journal-title":"PLoS Genet"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"e1002493","DOI":"10.1371\/journal.ppat.1002493","article-title":"Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in <italic>Bdellovibrio bacteriovorus<\/italic>","volume":"8","author":"L Hobley","year":"2012","journal-title":"PLoS Pathog"},{"key":"ref54","first-page":"2171","article-title":"Temperature-dependent expression of flagella of <italic>Listeria monocytogenes<\/italic> studied by electron microscopy, SDS-PAGE and western blotting","volume":"134","author":"M Peel","year":"1988","journal-title":"J Gen Microbiol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/mmi.12140","article-title":"Cycles of light and dark co-ordinate reversible colony differentiation in Listeria monocytogenes","volume":"87","author":"T Tiensuu","year":"2013","journal-title":"Mol Microbiol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"4028","DOI":"10.1073\/pnas.96.7.4028","article-title":"<italic>Vibrio cholerae<\/italic> O1 El Tor: identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formation","volume":"96","author":"FH Yildiz","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1046\/j.1365-2958.2001.02337.x","article-title":"The multicellular morphotypes of <italic>Salmonella typhimurium<\/italic> and <italic>Escherichia coli<\/italic> produce cellulose as the second component of the extracellular matrix","volume":"39","author":"X Zogaj","year":"2001","journal-title":"Mol Microbiol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1046\/j.1365-2958.2003.03670.x","article-title":"Biofilm formation at the air-liquid interface by the <italic>Pseudomonas fluorescens<\/italic> SBW25 wrinkly spreader requires an acetylated form of cellulose","volume":"50","author":"AJ Spiers","year":"2003","journal-title":"Mol Microbiol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"4457","DOI":"10.1128\/JB.186.14.4457-4465.2004","article-title":"Two genetic loci produce distinct carbohydrate-rich structural components of the <italic>Pseudomonas aeruginosa<\/italic> biofilm matrix","volume":"186","author":"L Friedman","year":"2004","journal-title":"J Bacteriol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1111\/j.1365-2958.2007.05817.x","article-title":"The second messenger bis-(3-5)-cyclic-GMP and its PilZ domain-containing receptor Alg44 are required for alginate biosynthesis in <italic>Pseudomonas aeruginosa<\/italic>","volume":"65","author":"M Merighi","year":"2007","journal-title":"Mol Microbiol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1574-6968.2007.00688.x","article-title":"<italic>ica<\/italic> and beyond: biofilm mechanisms and regulation in <italic>Staphylococcus epidermidis<\/italic> and <italic>Staphylococcus aureus<\/italic>","volume":"270","author":"JP O'Gara","year":"2007","journal-title":"FEMS Microbiol Lett"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/978-0-387-72124-8_17","article-title":"Regulation of biofilm formation in <italic>Yersinia pestis<\/italic>","volume":"603","author":"AG Bobrov","year":"2007","journal-title":"Adv Exp Med Biol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0923-2508(02)01316-5","article-title":"Molecular biology of cellulose production in bacteria","volume":"153","author":"U R\u00f6mling","year":"2002","journal-title":"Res Microbiol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/nature11744","article-title":"Crystallographic snapshot of cellulose synthesis and membrane translocation","volume":"493","author":"JL Morgan","year":"2013","journal-title":"Nature"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1046\/j.1365-2958.1998.00797.x","article-title":"Initiation of biofilm formation in <italic>Pseudomonas fluorescens<\/italic> WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis","volume":"28","author":"GA O'Toole","year":"1998","journal-title":"Mol Microbiol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"7711","DOI":"10.1128\/AEM.01065-06","article-title":"Resistance of <italic>Listeria monocytogenes<\/italic> biofilms to sanitizing agents in a simulated food processing environment","volume":"72","author":"Y Pan Jr","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"e1003015","DOI":"10.1371\/journal.ppat.1003015","article-title":"InlA promotes dissemination of <italic>Listeria monocytogenes<\/italic> to the mesenteric lymph nodes during food borne infection of mice","volume":"8","author":"EN Bou Ghanem","year":"2012","journal-title":"PLoS Pathog"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1128\/JB.187.1.382-387.2005","article-title":"Depolymerization of beta-1,6-N-acetyl-D-glucosamine disrupts the integrity of diverse bacterial biofilms","volume":"187","author":"Y Itoh","year":"2005","journal-title":"J Bacteriol"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1038\/emboj.2012.315","article-title":"Allosteric activation of exopolysaccharide synthesis through cyclic di-GMP-stimulated protein-protein interaction","volume":"32","author":"S Steiner","year":"2013","journal-title":"EMBO J"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.tim.2012.10.001","article-title":"Synthase-dependent exopolysaccharide secretion in Gram-negative bacteria","volume":"21","author":"JC Whitney","year":"2013","journal-title":"Trends Microbiol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.molcel.2010.03.001","article-title":"The c-di-GMP binding protein YcgR controls flagellar motor direction and speed to affect chemotaxis by a \u201cbackstop brake\u201d mechanism","volume":"38","author":"K Paul","year":"2010","journal-title":"Mol Cell"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1111\/j.1365-2958.2010.07179.x","article-title":"A posttranslational, c-di-GMP-dependent mechanism regulating bacterial flagellar motility","volume":"76","author":"X Fang","year":"2010","journal-title":"Mol Microbiol"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"6973","DOI":"10.1073\/pnas.86.18.6973","article-title":"Migration of bacteria in semisolid agar","volume":"86","author":"AJ Wolfe","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.cell.2010.01.018","article-title":"Second messenger-mediated adjustment of bacterial swimming velocity","volume":"141","author":"A Boehm","year":"2010","journal-title":"Cell"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"4112","DOI":"10.1073\/pnas.0607738104","article-title":"DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in <italic>Caulobacter crescentus<\/italic>","volume":"104","author":"M Christen","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1126\/science.1157877","article-title":"A molecular clutch disables flagella in the <italic>Bacillus subtilis<\/italic> biofilm","volume":"320","author":"KM Blair","year":"2008","journal-title":"Science"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"e1001243","DOI":"10.1371\/journal.pgen.1001243","article-title":"The EpsE flagellar clutch is bifunctional and synergizes with EPS biosynthesis to promote <italic>Bacillus subtilis<\/italic> biofilm formation","volume":"6","author":"SB Guttenplan","year":"2010","journal-title":"PLoS Genet"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1128\/JB.01789-12","article-title":"Coordinated cyclic-di-GMP repression of <italic>Salmonella<\/italic> motility through YcgR and cellulose","volume":"195","author":"V Zorraquino","year":"2013","journal-title":"J Bacteriol"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.micpath.2006.08.003","article-title":"An in vitro cell-culture model demonstrates internalin- and hemolysin-independent translocation of <italic>Listeria monocytogenes<\/italic> across M cells","volume":"41","author":"S Corr","year":"2006","journal-title":"Microb Pathog"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.1128\/IAI.66.8.3758-3766.1998","article-title":"Interactions of the invasive pathogens <italic>Salmonella typhimurium<\/italic>, <italic>Listeria monocytogenes<\/italic>, and <italic>Shigella flexneri<\/italic> with M cells and murine Peyer&apos;s patches","volume":"66","author":"VB Jensen","year":"1998","journal-title":"Infect Immun"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1006\/mpat.1997.0144","article-title":"Penetration of <italic>Listeria monocytogenes<\/italic> in mice infected by the oral route","volume":"23","author":"AJ Marco","year":"1997","journal-title":"Microb Pathog"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1126\/science.1102901","article-title":"CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance","volume":"307","author":"JH Niess","year":"2005","journal-title":"Science"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/86373","article-title":"Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria","volume":"2","author":"M Rescigno","year":"2001","journal-title":"Nat Immunol"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1126\/science.1189801","article-title":"c-di-AMP secreted by intracellular <italic>Listeria monocytogenes<\/italic> activates a host type I interferon response","volume":"328","author":"JJ Woodward","year":"2010","journal-title":"Science"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1128\/IAI.00999-10","article-title":"The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of STING in the in vivo interferon response to <italic>Listeria monocytogenes<\/italic> and cyclic dinucleotides","volume":"79","author":"JD Sauer","year":"2011","journal-title":"Infect Immun"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/nature10429","article-title":"STING is a direct innate immune sensor of cyclic di-GMP","volume":"478","author":"DL Burdette","year":"2011","journal-title":"Nature"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1084\/jem.20091746","article-title":"Induction of IFN-alphabeta enables <italic>Listeria monocytogenes<\/italic> to suppress macrophage activation by IFN-gamma","volume":"207","author":"M Rayamajhi","year":"2010","journal-title":"J Exp Med"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1128\/IAI.06286-11","article-title":"Hyperinduction of host beta interferon by a <italic>Listeria monocytogenes<\/italic> strain naturally overexpressing the multidrug efflux pump MdrT","volume":"80","author":"KT Schwartz","year":"2012","journal-title":"Infect Immun"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"6943","DOI":"10.1128\/AEM.69.11.6943-6945.2003","article-title":"Development of a synthetic minimal medium for <italic>Listeria monocytogenes<\/italic>","volume":"69","author":"HN Tsai","year":"2003","journal-title":"Appl Environ Microbiol"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/0300-9084(92)90143-3","article-title":"Use of a new integrational vector to investigate compartment-specific expression of the <italic>Bacillus subtilis spoIIM<\/italic> gene","volume":"74","author":"K Smith","year":"1992","journal-title":"Biochimie"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0378-1119(90)90479-B","article-title":"High-efficiency transformation of <italic>Listeria monocytogenes<\/italic> by electroporation of penicillin-treated cells","volume":"94","author":"SF Park","year":"1990","journal-title":"Gene"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"4418","DOI":"10.1128\/JB.01967-06","article-title":"Flagellar motility is critical for <italic>Listeria monocytogenes<\/italic> biofilm formation","volume":"189","author":"KP Lemon","year":"2007","journal-title":"J Bacteriol"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1128\/AEM.69.6.3640-3645.2003","article-title":"Adhesion, invasion and translocation characteristics of <italic>Listeria monocytogenes<\/italic> serotypes in Caco-2 cell mouse models","volume":"69","author":"ZW Jaradat","year":"2003","journal-title":"Appl Environ Microbiol"},{"key":"ref94","doi-asserted-by":"crossref","first-page":"11613","DOI":"10.1074\/jbc.M900231200","article-title":"Septin 11 restricts InlB-mediated invasion by <italic>Listeria<\/italic>","volume":"284","author":"S Mostowy","year":"2009","journal-title":"J Biol Chem"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1128\/AEM.71.1.247-254.2005","article-title":"Biofilm formation by <italic>Esherichia coli<\/italic> O157:H7 on stainless steel: Effect of exopolysaccharide and curli production on its resistance to chlorine","volume":"71","author":"J-H Ryu","year":"2005","journal-title":"Appl Environ Microbiol"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1128\/AEM.02612-09","article-title":"Single-cell techniques using chromosomally tagged fluorescent bacteria to study <italic>Listeria monocytogenes<\/italic> infection processes","volume":"76","author":"D Balestrino","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.1128\/AEM.00314-08","article-title":"Tools for functional postgenomic analysis of <italic>Listeria monocytogenes<\/italic>","volume":"74","author":"IR Monk","year":"2008","journal-title":"Appl Environ Microbiol"}],"container-title":["PLoS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1004301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T00:41:20Z","timestamp":1598143280000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1004301"}},"subtitle":[],"editor":[{"given":"Mary","family":"O'Riordan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,8,7]]},"references-count":97,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2014,8,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1004301","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,7]]}}}