{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:51:41Z","timestamp":1791294701942,"version":"4.1.0"},"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T00:00:00Z","timestamp":1414022400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1004470","type":"journal-article","created":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T17:27:03Z","timestamp":1414085223000},"page":"e1004470","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":51,"title":["Listeria monocytogenes Dampens the DNA Damage Response"],"prefix":"10.1371","volume":"10","author":[{"given":"Ascel","family":"Samba-Louaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge M.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Anne","family":"Nahori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Villiers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovic","family":"Deriano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9lanie A.","family":"Hamon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Cossart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,10,23]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.molcel.2010.09.019","article-title":"The DNA damage response: making it safe to play with knives","volume":"40","author":"A Ciccia","year":"2010","journal-title":"Mol Cell"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm1963","article-title":"Poly(ADP-ribose): novel functions for an old molecule","volume":"7","author":"V Schreiber","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1126\/science.1150034","article-title":"Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase","volume":"318","author":"NK Kolas","year":"2007","journal-title":"Science"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1016\/j.febslet.2011.05.056","article-title":"The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks","volume":"585","author":"S Bekker-Jensen","year":"2011","journal-title":"FEBS Lett"},{"key":"ref5","article-title":"53BP1: pro choice in DNA repair","author":"M Zimmermann","year":"2013","journal-title":"Trends Cell Biol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/nrm3047","article-title":"The MRE11 complex: starting from the ends","volume":"12","author":"TH Stracker","year":"2011","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1038\/nature08467","article-title":"The DNA-damage response in human biology and disease","volume":"461","author":"SP Jackson","year":"2009","journal-title":"Nature"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.tim.2007.01.003","article-title":"Using or abusing: viruses and the cellular DNA damage response","volume":"15","author":"CE Lilley","year":"2007","journal-title":"Trends Microbiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.chom.2012.01.013","article-title":"Calpain activation by the Shigella flexneri effector VirA regulates key steps in the formation and life of the bacterium&apos;s epithelial niche","volume":"11","author":"J Bergounioux","year":"2012","journal-title":"Cell Host Microbe"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.chom.2013.05.010","article-title":"Chlamydia infection promotes host DNA damage and proliferation but impairs the DNA damage response","volume":"13","author":"C Chumduri","year":"2013","journal-title":"Cell Host Microbe"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"11537","DOI":"10.1073\/pnas.1001261107","article-title":"Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells","volume":"107","author":"G Cuevas-Ramos","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"4385","DOI":"10.1007\/s00018-013-1392-3","article-title":"The opportunistic pathogen Pseudomonas aeruginosa activates the DNA double-strand break signaling and repair pathway in infected cells","volume":"70","author":"S Elsen","year":"2013","journal-title":"Cell Mol Life Sci"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"14944","DOI":"10.1073\/pnas.1100959108","article-title":"Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells","volume":"108","author":"IM Toller","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1242\/jcs.117721","article-title":"Neisseria gonorrhoeae infection causes DNA damage and affects the expression of p21, p27 and p53 in non-tumor epithelial cells","volume":"126","author":"K Vielfort","year":"2013","journal-title":"J Cell Sci"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1126\/science.1127059","article-title":"Escherichia coli induces DNA double-strand breaks in eukaryotic cells","volume":"313","author":"JP Nougayrede","year":"2006","journal-title":"Science"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1469-0691.2009.03109.x","article-title":"Listeriosis: a resurgent foodborne infection","volume":"16","author":"F Allerberger","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"pii: a010009","DOI":"10.1101\/cshperspect.a010009","article-title":"Entry of Listeria monocytogenes in mammalian epithelial cells: an updated view","volume":"2","author":"J Pizarro-Cerda","year":"2012","journal-title":"Cold Spring Harb Perspect Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"19484","DOI":"10.1073\/pnas.1112371108","article-title":"Illuminating the landscape of host-pathogen interactions with the bacterium Listeria monocytogenes","volume":"108","author":"P Cossart","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.tim.2012.04.006","article-title":"Listeriolysin O: the swiss army knife of Listeria","volume":"20","author":"MA Hamon","year":"2012","journal-title":"Trends Microbiology"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"4257","DOI":"10.1128\/IAI.00614-12","article-title":"Role for telomerase in Listeria monocytogenes infection","volume":"80","author":"A Samba-Louaka","year":"2012","journal-title":"Infect Immun"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nprot.2006.5","article-title":"The comet assay: a method to measure DNA damage in individual cells","volume":"1","author":"PL Olive","year":"2006","journal-title":"Nat Protoc"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1128\/MCB.21.5.1719-1729.2001","article-title":"Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage","volume":"21","author":"L Anderson","year":"2001","journal-title":"Mol Cell Biol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/287745a0","article-title":"Unusual levels of (ADP-ribose)n and DNA synthesis in ataxia telangiectasia cells following gamma-ray irradiation","volume":"287","author":"MJ Edwards","year":"1980","journal-title":"Nature"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"5858","DOI":"10.1074\/jbc.273.10.5858","article-title":"DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139","volume":"273","author":"EP Rogakou","year":"1998","journal-title":"J Biol Chem"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/ncb2201","article-title":"53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress","volume":"13","author":"C Lukas","year":"2011","journal-title":"Nat Cell Biol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/35044005","article-title":"The DNA damage response: putting checkpoints in perspective","volume":"408","author":"BB Zhou","year":"2000","journal-title":"Nature"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1128\/IAI.52.1.50-55.1986","article-title":"Transposon mutagenesis as a tool to study the role of hemolysin in the virulence of Listeria monocytogenes","volume":"52","author":"JL Gaillard","year":"1986","journal-title":"Infect Immun"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1111\/j.1365-2958.1990.tb00578.x","article-title":"Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O","volume":"4","author":"E Michel","year":"1990","journal-title":"Mol Microbiol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/S1097-2765(03)00455-6","article-title":"Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1\/ATLD1) mice","volume":"12","author":"JW Theunissen","year":"2003","journal-title":"Mol Cell"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1128\/AEM.02612-09","article-title":"Single-cell techniques using chromosomally tagged fluorescent bacteria to study Listeria monocytogenes infection processes","volume":"76","author":"D Balestrino","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"ref31","first-page":"e51043","article-title":"Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes","volume":"19","author":"A Kuhbacher","year":"2013","journal-title":"J Vis Exp"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"928","DOI":"10.4161\/cc.27780","article-title":"Listeria monocytogenes induces host DNA damage and delays the host cell cycle to promote infection","volume":"13","author":"E Leitao","year":"2014","journal-title":"Cell Cycle"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1126\/science.290.5490.354","article-title":"A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein","volume":"290","author":"M Lara-Tejero","year":"2000","journal-title":"Science"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"e1004030","DOI":"10.1371\/journal.ppat.1004030","article-title":"Microbial pathogens trigger host DNA double-strand breaks whose abundance is reduced by plant defense responses","volume":"10","author":"J Song","year":"2014","journal-title":"PLoS Pathog"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/sj.cdd.4401843","article-title":"Signals from within: the DNA-damage-induced NF-kappaB response","volume":"13","author":"S Janssens","year":"2006","journal-title":"Cell Death Differ"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/cr.2010.179","article-title":"Nuclear initiated NF-kappaB signaling: NEMO and ATM take center stage","volume":"21","author":"S Miyamoto","year":"2011","journal-title":"Cell Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/nature12452","article-title":"DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance","volume":"501","author":"MA Ermolaeva","year":"2013","journal-title":"Nature"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1073\/pnas.1222694110","article-title":"DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking","volume":"110","author":"T Kondo","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/nature00863","article-title":"Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex","volume":"418","author":"TH Stracker","year":"2002","journal-title":"Nature"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1128\/IAI.55.11.2822-2829.1987","article-title":"In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2","volume":"55","author":"JL Gaillard","year":"1987","journal-title":"Infect Immun"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1038\/nature08963","article-title":"Listeria monocytogenes impairs SUMOylation for efficient infection","volume":"464","author":"D Ribet","year":"2010","journal-title":"Nature"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.ceb.2009.04.003","article-title":"Membrane injury by pore-forming proteins","volume":"21","author":"M Bischofberger","year":"2009","journal-title":"Curr Opin Cell Biol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1083\/jcb.200201081","article-title":"The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells","volume":"156","author":"IJ Glomski","year":"2002","journal-title":"J Cell Biol"}],"container-title":["PLoS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1004470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T23:11:24Z","timestamp":1598397084000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1004470"}},"subtitle":[],"editor":[{"given":"Raphael H.","family":"Valdivia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,10,23]]},"references-count":43,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2014,10,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1004470","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.723870887.793502511","asserted-by":"object"}]},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,23]]}}}