{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:14:19Z","timestamp":1790234059484,"version":"4.1.0"},"reference-count":87,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2015,5,21]],"date-time":"2015-05-21T00:00:00Z","timestamp":1432166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1004787","type":"journal-article","created":{"date-parts":[[2015,5,21]],"date-time":"2015-05-21T18:04:51Z","timestamp":1432231491000},"page":"e1004787","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":154,"title":["Intestinal Colonization Dynamics of Vibrio cholerae"],"prefix":"10.1371","volume":"11","author":[{"given":"Salvador","family":"Almagro-Moreno","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kali","family":"Pruss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald K.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,5,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1016\/S0140-6736(12)60436-X","article-title":"Cholera","volume":"379","author":"JB Harris","year":"2012","journal-title":"Lancet"},{"key":"ref2","unstructured":"CDC (2015) Centers for Disease Control and Prevention. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.cdc.gov\/\" xlink:type=\"simple\">http:\/\/www.cdc.gov\/<\/ext-link>"},{"key":"ref3","unstructured":"Minist\u00e8re de la Sant\u00e9 Publique et de la Population (2015) Minist\u00e8re de la Sant\u00e9 Publique et de la Population. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/mspp.gouv.ht\/newsite\/\" xlink:type=\"simple\">http:\/\/mspp.gouv.ht\/newsite\/<\/ext-link>"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3389\/fmicb.2013.00375","article-title":"Environmental reservoirs and mechanisms of persistence of <italic>Vibrio cholerae<\/italic>","volume":"4","author":"C Lutz","year":"2013","journal-title":"Front Microbiol"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"OH-0003-2012","DOI":"10.1128\/microbiolspec.OH-0003-2012","article-title":"Cholera: Environmental reservoirs and impact on disease transmission","volume":"1","author":"S Almagro-Moreno","year":"2013","journal-title":"Microbiol Spectrum"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1128\/CMR.8.1.48","article-title":"Cholera","volume":"8","author":"JB Kaper","year":"1995","journal-title":"Clin Microbiol Rev"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1046\/j.1365-2958.2002.02857.x","article-title":"Identification of novel factors involved in colonization and acid tolerance of <italic>Vibrio cholerae<\/italic>","volume":"43","author":"DS Merrell","year":"2002","journal-title":"Mol Microbiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1128\/JB.183.9.2746-2754.2001","article-title":"The ToxR-mediated organic acid tolerance response of <italic>Vibrio cholerae<\/italic> requires OmpU","volume":"183","author":"DS Merrell","year":"2001","journal-title":"J Bacteriol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"5342","DOI":"10.1128\/JB.182.19.5342-5350.2000","article-title":"Regulation of <italic>Vibrio cholerae<\/italic> genes required for acid tolerance by a member of the \u201cToxR-Like\u201d family of transcriptional regulators","volume":"182","author":"DS Merrell","year":"2000","journal-title":"J Bacteriol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"4181","DOI":"10.1128\/JB.00193-10","article-title":"The LysR-type virulence activator AphB regulates the expression of genes in <italic>Vibrio cholerae<\/italic> in response to low pH and anaerobiosis","volume":"192","author":"G Kovacikova","year":"2010","journal-title":"J Bacteriol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/infdis\/129.1.45","article-title":"Response of man to infection with <italic>Vibrio cholerae<\/italic>. I. Clinical, serologic, and bacteriologic responses to a known inoculum","volume":"129","author":"RA Cash","year":"1974","journal-title":"J Infect Dis"},{"key":"ref12","first-page":"443","article-title":"Acute enteric infections in children. New prospects for treatment and prevention","author":"MM Levine","year":"1981"},{"key":"ref13","first-page":"31","article-title":"Gastric acidity in cholera and noncholera diarrhoea","volume":"47","author":"GH Sack","year":"1972","journal-title":"Bull World Health Organ"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/S0140-6736(78)91568-4","article-title":"Cholera, non-vibrio cholera, and stomach acid","volume":"2","author":"DR Nalin","year":"1978","journal-title":"Lancet"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/0895-4356(90)90103-V","article-title":"Low gastric acid as a risk factor for cholera transmission: application of a new non-invasive gastric acid field test","volume":"43","author":"FP Van Loon","year":"1990","journal-title":"J Clin Epidemiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1038\/nbt0985-817","article-title":"Viable but non-culturable <italic>Vibrio cholerae<\/italic> and related pathogens in the environment: Implications for release of genetically engineered microorganisms","volume":"3","author":"RR Colwell","year":"1985","journal-title":"Nat Biotechnol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"17801","DOI":"10.1073\/pnas.0705599104","article-title":"Viable but nonculturable <italic>Vibrio cholerae<\/italic> O1 in biofilms in the aquatic environment and their role in cholera transmission","volume":"104","author":"M Alam","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/BF00327795","article-title":"Viable but non-culturable <italic>Vibrio cholerae<\/italic> O1 revert to a cultivable state in the human intestine","volume":"12","author":"RR Colwell","year":"1996","journal-title":"World J Microbiol Biotechnol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/j.1462-2920.2006.01206.x","article-title":"Gene expression profile of <italic>Vibrio cholerae<\/italic> in the cold stress-induced viable but non-culturable state","volume":"9","author":"H Asakura","year":"2007","journal-title":"Environ Microbiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1046\/j.1365-2672.2004.02166.x","article-title":"Induction of viable but nonculturable state in <italic>Vibrio parahaemolyticus<\/italic> and its susceptibility to environmental stresses","volume":"96","author":"HC Wong","year":"2004","journal-title":"J Appl Microbiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nature00778","article-title":"Host-induced epidemic spread of the cholera bacterium","volume":"417","author":"DS Merrell","year":"2002","journal-title":"Nature"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e1001102","DOI":"10.1371\/journal.ppat.1001102","article-title":"A bistable switch and anatomical site control <italic>Vibrio cholerae<\/italic> virulence gene expression in the intestine","volume":"6","author":"AT Nielsen","year":"2010","journal-title":"PLoS Pathog"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1073\/pnas.84.9.2833","article-title":"Use of <italic>phoA<\/italic> gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin","volume":"84","author":"RK Taylor","year":"1987","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1146\/annurev.micro.54.1.49","article-title":"Biofilm formation as microbial development","volume":"54","author":"G O'Toole","year":"2000","journal-title":"Annu Rev Microbiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"6350","DOI":"10.1073\/pnas.0601277103","article-title":"Transmissibility of cholera: in vivo-formed biofilms and their relationship to infectivity and persistence in the environment","volume":"103","author":"SM Faruque","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.1128\/IAI.00048-10","article-title":"Growth in a Biofilm Induces a Hyperinfectious Phenotype in <italic>Vibrio cholerae<\/italic>","volume":"78","author":"R Tamayo","year":"2010","journal-title":"Infect Immun"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1365-2958.2005.04846.x","article-title":"Bile acids stimulate biofilm formation in <italic>Vibrio cholerae<\/italic>","volume":"59","author":"DT Hung","year":"2006","journal-title":"Mol Microbiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1128\/IAI.02617-14","article-title":"Host intestinal signal-promoted biofilm dispersal induces <italic>Vibrio cholerae<\/italic> colonization","volume":"83","author":"AJ Hay","year":"2015","journal-title":"Infect Immun"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1128\/IAI.68.3.1491-1497.2000","article-title":"The virulence regulatory protein ToxR mediates enhanced bile resistance in <italic>Vibrio cholerae<\/italic> and other pathogenic <italic>Vibrio<\/italic> species","volume":"68","author":"D Provenzano","year":"2000","journal-title":"Infect Immun"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"3577","DOI":"10.1128\/IAI.72.6.3577-3583.2004","article-title":"The <italic>Vibrio cholerae<\/italic> ToxR-regulated porin OmpU confers resistance to antimicrobial peptides","volume":"72","author":"J Mathur","year":"2004","journal-title":"Infect Immun"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1073\/pnas.0237386100","article-title":"Reduction of cholera in Bangladeshi villages by simple filtration","volume":"100","author":"RR Colwell","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref32","first-page":"1e00034","article-title":"Simple sari cloth filtration of water is sustainable and continues to protect villagers from cholera in Matlab, Bangladesh","volume":"1","author":"A Huq","year":"2010","journal-title":"mBio"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1749-6632.1994.tb19852.x","article-title":"Environmental reservoir of <italic>Vibrio cholerae<\/italic>. The causative agent of cholera","volume":"740","author":"RR Colwell","year":"1994","journal-title":"Ann N Y Acad Sci"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"6350","DOI":"10.1073\/pnas.0601277103","article-title":"Transmissibility of cholera: In vivo-formed biofilms and their relationship to infectivity and persistence in the environment","volume":"103","author":"SM Faruque","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"9769","DOI":"10.1073\/pnas.0802241105","article-title":"Mucosal penetration primes <italic>Vibrio cholerae<\/italic> for host colonization by repressing quorum sensing","volume":"105","author":"Z Liu","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"6889","DOI":"10.1073\/pnas.111581598","article-title":"Selection for in vivo regulators of bacterial virulence","volume":"98","author":"SH Lee","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1128\/IAI.11.5.890-897.1975","article-title":"Motility as a virulence factor for <italic>Vibrio cholerae<\/italic>","volume":"11","author":"MN Guentzel","year":"1975","journal-title":"Infect Immun"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"e1004405","DOI":"10.1371\/journal.ppat.1004405","article-title":"Insights into <italic>Vibrio cholerae<\/italic> intestinal colonization from monitoring fluorescently labeled bacteria","volume":"10","author":"YA Millet","year":"2014","journal-title":"PLoS Pathog"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1128\/JB.183.12.3784-3790.2001","article-title":"Flagellum-independent surface migration of <italic>Vibrio cholerae<\/italic> and <italic>Escherichia coli<\/italic>","volume":"183","author":"II Brown","year":"2001","journal-title":"J Bacteriol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1128\/IAI.34.1.222-233.1981","article-title":"Role of chemotaxis in the association of motile bacteria with intestinal mucosa: fitness and virulence of nonchemotactic <italic>Vibrio cholerae<\/italic> mutants in infant mice","volume":"34","author":"R Freter","year":"1981","journal-title":"Infect Immun"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"5018","DOI":"10.1073\/pnas.0308052101","article-title":"Both chemotaxis and net motility greatly influence the infectivity of <italic>Vibrio cholerae<\/italic>","volume":"101","author":"SM Butler","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.chom.2013.11.001","article-title":"Tn-Seq analysis of <italic>Vibrio cholerae<\/italic> intestinal colonization reveals a role for T6SS-mediated antibacterial activity in the host","volume":"14","author":"Y Fu","year":"2013","journal-title":"Cell Host Microbe"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"e1003800","DOI":"10.1371\/journal.ppat.1003800","article-title":"Gene fitness landscapes of <italic>Vibrio cholerae<\/italic> at important stages of its life cycle","volume":"9","author":"HD Kamp","year":"2013","journal-title":"PLoS Pathog"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S1286-4579(00)00392-0","article-title":"Mechanisms of bacterial resistance and response to bile","volume":"2","author":"JS Gunn","year":"2000","journal-title":"Microbe Infect"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1128\/IAI.65.3.1131-1134.1997","article-title":"Bile affects production of virulence factors and motility of <italic>Vibrio cholerae<\/italic>","volume":"65","author":"S Gupta","year":"1997","journal-title":"Infect Immun"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"5542","DOI":"10.1128\/IAI.01094-07","article-title":"Regulatory networks controlling <italic>Vibrio cholerae<\/italic> virulence gene expression","volume":"75","author":"JS Matson","year":"2007","journal-title":"Infect Immun"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"5403","DOI":"10.1073\/pnas.88.12.5403","article-title":"Regulatory cascade controls virulence in <italic>Vibrio cholerae<\/italic>","volume":"88","author":"VJ DiRita","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"6974","DOI":"10.1128\/jb.174.21.6974-6980.1992","article-title":"The virulence gene activator ToxT from <italic>Vibrio cholerae<\/italic> is a member of the AraC family of transcriptional activators","volume":"174","author":"DE Higgins","year":"1992","journal-title":"J Bacteriol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1046\/j.1365-2958.1997.2191585.x","article-title":"A branch in the ToxR regulatory cascade of <italic>Vibrio cholerae<\/italic> revealed by characterization of <italic>toxT<\/italic> mutant strains","volume":"23","author":"GA Champion","year":"1997","journal-title":"Mol Microbiol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00018-008-7496-5","article-title":"Cholera toxin structure, gene regulation and pathophysiological and immunological aspects","volume":"65","author":"J Sanchez","year":"2008","journal-title":"Cell Mol Life Sci"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1128\/IAI.01435-06","article-title":"Effect of fatty acids and cholesterol present in bile on expression of virulence factors and motility of <italic>Vibrio cholerae<\/italic>","volume":"75","author":"A Chatterjee","year":"2007","journal-title":"Infect Immun"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1128\/JB.181.5.1508-1514.1999","article-title":"Environmental signals modulate ToxT-dependent virulence factor expression in <italic>Vibrio cholerae<\/italic>","volume":"181","author":"DA Schuhmacher","year":"1999","journal-title":"J Bacteriol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1111\/j.1365-2958.2005.04897.x","article-title":"Characterization of functional domains of the <italic>Vibrio cholerae<\/italic> virulence regulator ToxT","volume":"58","author":"MG Prouty","year":"2005","journal-title":"Mol Microbiol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"28644","DOI":"10.1074\/jbc.M111.258780","article-title":"N-terminal residues of the <italic>Vibrio cholerae<\/italic> virulence regulatory protein ToxT involved in dimerization and modulation by fatty acids","volume":"286","author":"BM Childers","year":"2011","journal-title":"J Biol Chem"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"2860","DOI":"10.1073\/pnas.0915021107","article-title":"Structure of <italic>Vibrio cholerae<\/italic> ToxT reveals a mechanism for fatty acid regulation of virulence genes","volume":"107","author":"MJ Lowden","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.1128\/IAI.00409-09","article-title":"Bicarbonate induces <italic>Vibrio cholerae<\/italic> virulence gene expression by enhancing ToxT activity","volume":"77","author":"BH Abuaita","year":"2009","journal-title":"Infect Immun"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"3872","DOI":"10.1128\/JB.01824-14","article-title":"Bicarbonate increases binding affinity of <italic>Vibrio cholerae<\/italic> ToxT to virulence gene promoters","volume":"196","author":"JJ Thomson","year":"2014","journal-title":"J Bacteriol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1128\/JB.02068-14","article-title":"A small unstructured region in <italic>Vibrio cholerae<\/italic> ToxT mediates the response to positive and negative effectors and ToxT proteolysis","volume":"197","author":"JJ Thomson","year":"2015","journal-title":"J Bacteriol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1365-2036.1994.tb00319.x","article-title":"Gastroduodenal bicarbonate secretion","volume":"8","author":"DL Hogan","year":"1994","journal-title":"Aliment Pharmacol Ther"},{"key":"ref60","first-page":"23","article-title":"Gastroduodenal mucosal alkaline secretion and mucosal protection","volume":"16","author":"G Flemstr\u00f6m","year":"2001","journal-title":"News Physiol Sci"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/nrmicro2538","article-title":"Mucin dynamics and enteric pathogens","volume":"9","author":"MA McGuckin","year":"2011","journal-title":"Nat Rev Microbiol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1128\/IAI.42.2.639-644.1983","article-title":"<italic>Vibrio cholerae<\/italic> soluble hemagglutinin\/protease is a metalloenzyme","volume":"42","author":"BA Booth","year":"1983","journal-title":"Infect Immun"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1099\/mic.0.26086-0","article-title":"Haemagglutinin\/protease expression and mucin gel penetration in El Tor biotype <italic>Vibrio cholerae<\/italic>","volume":"149","author":"AJ Silva","year":"2003","journal-title":"Microbiology"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S1534-5807(03)00295-8","article-title":"Quorum sensing-dependent biofilms enhance colonization in <italic>Vibrio cholerae<\/italic>","volume":"5","author":"J Zhu","year":"2003","journal-title":"Dev Cell"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1099\/mic.0.044529-0","article-title":"TagA is a secreted protease of <italic>Vibrio cholerae<\/italic> that specifically cleaves mucin glycoproteins","volume":"157","author":"RL Szabady","year":"2011","journal-title":"Microbiology"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1073\/pnas.052694299","article-title":"Quorum-sensing regulators control virulence gene expression in <italic>Vibrio cholerae<\/italic>","volume":"99","author":"J Zhu","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1128\/IAI.60.2.406-415.1992","article-title":"Role of <italic>Vibrio cholerae<\/italic> neuraminidase in the function of cholera toxin","volume":"60","author":"JE Galen","year":"1992","journal-title":"Infect Immun"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1073\/pnas.72.7.2520","article-title":"Interaction of cholera toxin and membrane GM1 ganglioside of small intestine","volume":"72","author":"J Holmgren","year":"1975","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"5260","DOI":"10.1128\/JB.00378-11","article-title":"Protection and attachment of <italic>Vibrio cholerae<\/italic> mediated by the toxin-coregulated pilus in the infant mouse model","volume":"193","author":"SJ Krebs","year":"2011","journal-title":"J Bacteriol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1038\/nature04249","article-title":"A colonization factor links <italic>Vibrio cholerae<\/italic> environmental survival and human infection","volume":"438","author":"TJ Kirn","year":"2005","journal-title":"Nature"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"6555","DOI":"10.1128\/JB.00949-09","article-title":"The <italic>Vibrio cholerae<\/italic> flagellar regulatory hierarchy controls expression of virulence factors","volume":"191","author":"KA Syed","year":"2009","journal-title":"J Bacteriol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1093\/infdis\/147.5.864","article-title":"The role of the flagellum in the adherence of <italic>Vibrio cholerae<\/italic>","volume":"147","author":"SR Attridge","year":"1983","journal-title":"J Infect Dis"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"11614","DOI":"10.1073\/pnas.1102360108","article-title":"Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens","volume":"108","author":"AM Krachler","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1128\/IAI.63.11.4433-4438.1995","article-title":"The OmpU outer membrane protein, a potential adherence factor of <italic>Vibrio cholerae<\/italic>","volume":"63","author":"V Sperandio","year":"1995","journal-title":"Infect Immun"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"4968","DOI":"10.1128\/IAI.01615-07","article-title":"Intestinal adherence of <italic>Vibrio cholerae<\/italic> involves a coordinated interaction between colonization factor GbpA and mucin","volume":"76","author":"R Bhowmick","year":"2008","journal-title":"Infect Immun"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"e1002373","DOI":"10.1371\/journal.ppat.1002373","article-title":"The <italic>Vibrio cholerae<\/italic> colonization factor GbpA possesses a modular structure that governs binding to different host surfaces","volume":"8","author":"E Wong","year":"2012","journal-title":"PLoS Pathog"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1128\/AEM.65.3.1348-1351.1999","article-title":"Role of surface proteins in <italic>Vibrio cholerae<\/italic> attachment to chitin","volume":"65","author":"R Tarsi","year":"1999","journal-title":"Appl Environ Microbiol"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"6590","DOI":"10.1128\/JB.183.22.6590-6597.2001","article-title":"<italic>Vibrio fischeri<\/italic> outer membrane protein OmpU plays a role in normal symbiotic colonization","volume":"183","author":"F Aeckersberg","year":"2001","journal-title":"J Bacteriol"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.mimet.2010.12.014","article-title":"An atomic force microscopy method for the detection of binding forces between bacteria and a lipid bilayer containing higher order gangliosides","volume":"84","author":"EL Adams","year":"2011","journal-title":"J Microbiol Methods"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1128\/IAI.00279-09","article-title":"Sialic acid catabolism confers a competitive advantage to pathogenic <italic>Vibrio cholerae<\/italic> in the mouse intestine","volume":"77","author":"S Almagro-Moreno","year":"2009","journal-title":"Infect Immun"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0092-8674(00)81551-2","article-title":"Regulation and temporal expression patterns of <italic>Vibrio cholerae<\/italic> virulence genes during infection","volume":"99","author":"SH Lee","year":"1999","journal-title":"Cell"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1111\/j.1365-2958.2011.07664.x","article-title":"Two gene clusters co-ordinate for a functional N-acetylglucosamine catabolic pathway in <italic>Vibrio cholerae<\/italic>","volume":"80","author":"S Ghosh","year":"2011","journal-title":"Mol Microbiol"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1111\/j.1365-2958.2010.07397.x","article-title":"The <italic>Vibrio cholerae<\/italic> virulence regulatory cascade controls glucose uptake through activation of TarA, a small regulatory RNA","volume":"78","author":"AL Richard","year":"2010","journal-title":"Mol Microbiol"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"3606","DOI":"10.1128\/JB.181.11.3606-3609.1999","article-title":"A role for the mannose-sensitive hemagglutinin in biofilm formation by <italic>Vibrio cholerae<\/italic> El Tor","volume":"181","author":"PI Watnick","year":"1999","journal-title":"J Bacteriol"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1046\/j.1365-2958.2000.01764.x","article-title":"Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization by <italic>Vibrio cholerae<\/italic>","volume":"35","author":"TJ Kirn","year":"2000","journal-title":"Mol Microbiol"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1126\/science.272.5270.1910","article-title":"Lysogenic conversion by a filamentous phage encoding cholera toxin","volume":"272","author":"MK Waldor","year":"1996","journal-title":"Science"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1046\/j.1365-2958.2003.03546.x","article-title":"Secretion of a soluble colonization factor by the TCP type 4 pilus biogenesis pathway in <italic>Vibrio cholerae<\/italic>","volume":"49","author":"TJ Kirn","year":"2003","journal-title":"Mol Microbiol"}],"container-title":["PLOS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1004787","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T12:47:26Z","timestamp":1599050846000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1004787"}},"subtitle":[],"editor":[{"given":"James B.","family":"Bliska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,5,21]]},"references-count":87,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2015,5,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1004787","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,21]]}}}