{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:05:18Z","timestamp":1791317118524,"version":"4.3.1"},"reference-count":74,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2016,1,27]],"date-time":"2016-01-27T00:00:00Z","timestamp":1453852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1005411","type":"journal-article","created":{"date-parts":[[2016,1,27]],"date-time":"2016-01-27T13:56:17Z","timestamp":1453902977000},"page":"e1005411","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":82,"title":["An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism"],"prefix":"10.1371","volume":"12","author":[{"given":"Hao","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxun","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Khedri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Diaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajit","family":"Varki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George F.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,1,27]]},"reference":[{"issue":"Suppl 4","key":"ref1","doi-asserted-by":"crossref","first-page":"D49","DOI":"10.1016\/j.vaccine.2008.07.039","article-title":"The biology of influenza viruses","volume":"26","author":"NM Bouvier","year":"2008","journal-title":"Vaccine"},{"key":"ref2","doi-asserted-by":"crossref","DOI":"10.1186\/1743-422X-10-321","article-title":"Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase","volume":"10","author":"M Cohen","year":"2013","journal-title":"Virology Journal"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"157","DOI":"10.7883\/yoken.63.157","article-title":"The molecular virology and reverse genetics of influenza C virus","volume":"63","author":"Y Muraki","year":"2010","journal-title":"Japanese journal of infectious diseases"},{"issue":"4806","key":"ref4","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1126\/science.3589663","article-title":"Selective inactivation of influenza C esterase: a probe for detecting 9-O-acetylated sialic acids","volume":"236","author":"EA Muchmore","year":"1987","journal-title":"Science"},{"issue":"5","key":"ref5","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1002\/jmv.23756","article-title":"Influenza C virus infection in military recruits\u2014symptoms and clinical manifestation","volume":"86","author":"J Kauppila","year":"2014","journal-title":"Journal of medical virology"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1128\/JCM.01555-06","article-title":"A nationwide epidemic of influenza C virus infection in Japan in 2004","volume":"45","author":"Y Matsuzaki","year":"2007","journal-title":"J Clin Microbiol"},{"issue":"8","key":"ref7","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/jmv.21218","article-title":"Study of influenza C virus infection in France","volume":"80","author":"S Gouarin","year":"2008","journal-title":"Journal of medical virology"},{"issue":"6","key":"ref8","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1097\/INF.0b013e3181a064b2","article-title":"Acute encephalopathy associated with influenza C virus infection","volume":"28","author":"M Takayanagi","year":"2009","journal-title":"The Pediatric infectious disease journal"},{"issue":"9","key":"ref9","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1086\/502973","article-title":"Clinical features of influenza C virus infection in children","volume":"193","author":"Y Matsuzaki","year":"2006","journal-title":"The Journal of infectious diseases"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jinf.2014.03.016","article-title":"Influenza C virus high seroprevalence rates observed in 3 different population groups","volume":"69","author":"N Salez","year":"2014","journal-title":"The Journal of infection"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1017\/S0950268800052225","article-title":"Serological studies of influenza viruses in pigs in Great Britain 1991\u20132","volume":"114","author":"IH Brown","year":"1995","journal-title":"Epidemiology and infection"},{"issue":"12","key":"ref12","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1111\/j.1348-0421.1987.tb01351.x","article-title":"Distribution of the antibody to influenza C virus in dogs and pigs in Yamagata Prefecture, Japan","volume":"31","author":"K Ohwada","year":"1987","journal-title":"Microbiology and immunology"},{"issue":"Pt 3","key":"ref13","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1099\/0022-1317-72-3-711","article-title":"Prevalence of antibody to influenza C virus among pigs in Hyogo Prefecture, Japan","volume":"72","author":"M Yamaoka","year":"1991","journal-title":"The Journal of general virology"},{"issue":"Pt 1","key":"ref14","first-page":"177","article-title":"Isolation of influenza C virus from pigs and experimental infection of pigs with influenza C virus","volume":"64","author":"YJ Guo","year":"1983","journal-title":"The Journal of general virology"},{"issue":"1","key":"ref15","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0168-1702(96)01427-X","article-title":"Interspecies transmission of influenza C virus between humans and pigs","volume":"48","author":"H Kimura","year":"1997","journal-title":"Virus research"},{"issue":"Pt 11","key":"ref16","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1099\/0022-1317-65-11-1857","article-title":"Genome analysis of influenza C viruses isolated in 1981\/82 from pigs in China","volume":"65","author":"G Yuanji","year":"1984","journal-title":"The Journal of general virology"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0923-2516(06)80104-4","article-title":"Natural infection of dogs by influenza C virus","volume":"143","author":"JC Manuguerra","year":"1992","journal-title":"Research in virology"},{"issue":"4","key":"ref18","first-page":"367","article-title":"Natural infection of dogs by influenza C virus: a serological survey in Spain","volume":"16","author":"JC Manuguerra","year":"1993","journal-title":"The new microbiologica"},{"issue":"4","key":"ref19","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1136\/vr.101929","article-title":"Serological evidence of infection of dogs with human influenza viruses in Japan","volume":"174","author":"T Horimoto","year":"2014","journal-title":"The Veterinary record"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"e1003176","DOI":"10.1371\/journal.ppat.1003176","article-title":"Isolation of a novel swine influenza virus from Oklahoma in 2011 which is distantly related to human influenza C viruses","volume":"9","author":"BM Hause","year":"2013","journal-title":"PLoS Pathog"},{"issue":"2","key":"ref21","doi-asserted-by":"crossref","first-page":"e00031","DOI":"10.1128\/mBio.00031-14","article-title":"Characterization of a novel influenza virus in cattle and Swine: proposal for a new genus in the Orthomyxoviridae family","volume":"5","author":"BM Hause","year":"2014","journal-title":"mBio"},{"issue":"2","key":"ref22","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s00705-013-1815-3","article-title":"Genomic and evolutionary characterization of a novel influenza-C-like virus from swine","volume":"159","author":"Z Sheng","year":"2014","journal-title":"Archives of virology"},{"issue":"2","key":"ref23","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1128\/JVI.02718-14","article-title":"Cocirculation of two distinct genetic and antigenic lineages of proposed influenza D virus in cattle","volume":"89","author":"EA Collin","year":"2015","journal-title":"Journal of virology"},{"key":"ref24","article-title":"Replication and transmission of novel bovine influenza D virus in guinea pig model","author":"C Sreenivasan","year":"2015","journal-title":"Journal of virology"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s11262-014-1107-3","article-title":"Identification of a potential novel type of influenza virus in Bovine in China","volume":"49","author":"WM Jiang","year":"2014","journal-title":"Virus genes"},{"issue":"2","key":"ref26","doi-asserted-by":"crossref","first-page":"368","DOI":"10.3201\/eid2102.141449","article-title":"Influenza D virus in cattle, France, 2011\u20132014","volume":"21","author":"MF Ducatez","year":"2015","journal-title":"Emerging infectious diseases"},{"issue":"12","key":"ref27","first-page":"1351","article-title":"The epidemiology of bovine respiratory disease: what is the evidence for preventive measures?","volume":"51","author":"JD Taylor","year":"2010","journal-title":"The Canadian veterinary journal La revue veterinaire canadienne"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1111\/jvim.12597","article-title":"Structured literature review of responses of cattle to viral and bacterial pathogens causing bovine respiratory disease complex","volume":"29","author":"GP Grissett","year":"2015","journal-title":"Journal of veterinary internal medicine \/ American College of Veterinary Internal Medicine"},{"key":"ref29","article-title":"Serological evidence for the presence of influenza D virus in small ruminants","author":"M Quast","year":"2015","journal-title":"Veterinary microbiology"},{"issue":"16","key":"ref30","doi-asserted-by":"crossref","first-page":"9077","DOI":"10.1128\/JVI.00235-13","article-title":"Structure and receptor binding specificity of hemagglutinin H13 from avian influenza A virus H13N6","volume":"87","author":"X Lu","year":"2013","journal-title":"J Virol"},{"issue":"7","key":"ref31","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s13238-013-3906-z","article-title":"Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut)","volume":"4","author":"X Lu","year":"2013","journal-title":"Protein & Cell"},{"issue":"10","key":"ref32","doi-asserted-by":"crossref","first-page":"5949","DOI":"10.1128\/JVI.00545-13","article-title":"Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution","volume":"87","author":"W Zhang","year":"2013","journal-title":"J Virol"},{"issue":"6139","key":"ref33","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1126\/science.1236787","article-title":"An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level","volume":"340","author":"W Zhang","year":"2013","journal-title":"Science"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.1099\/0022-1317-76-10-2529","article-title":"The Catalytic Triad of the Influenza-C Virus Glycoprotein Hef Esterase\u2014Characterization by Site-Directed Mutagenesis and Functional-Analysis","volume":"76","author":"S Pleschka","year":"1995","journal-title":"J Gen Virol"},{"issue":"6706","key":"ref35","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/23974","article-title":"Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus","volume":"396","author":"PB Rosenthal","year":"1998","journal-title":"Nature"},{"issue":"27","key":"ref36","doi-asserted-by":"crossref","first-page":"22593","DOI":"10.1074\/jbc.M112.359323","article-title":"Cross-comparison of protein recognition of sialic acid diversity on two novel sialoglycan microarrays","volume":"287","author":"V Padler-Karavani","year":"2012","journal-title":"The Journal of biological chemistry"},{"issue":"43","key":"ref37","doi-asserted-by":"crossref","first-page":"16874","DOI":"10.1073\/pnas.0708363104","article-title":"Structural basis for receptor specificity of influenza B virus hemagglutinin","volume":"104","author":"Q Wang","year":"2007","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6155","key":"ref38","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1126\/science.1242917","article-title":"Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses","volume":"342","author":"Y Shi","year":"2013","journal-title":"Science"},{"issue":"37","key":"ref39","doi-asserted-by":"crossref","first-page":"15897","DOI":"10.1073\/pnas.0904266106","article-title":"Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases","volume":"106","author":"MA Langereis","year":"2009","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"12","key":"ref40","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/molbev\/mst197","article-title":"MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0","volume":"30","author":"K Tamura","year":"2013","journal-title":"Mol Biol Evol"},{"issue":"3","key":"ref41","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1074\/jbc.M210103200","article-title":"Observation of an arsenic adduct in an acetyl esterase crystal structure","volume":"278","author":"X Zhu","year":"2003","journal-title":"The Journal of biological chemistry"},{"issue":"3\u20134","key":"ref42","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF01310831","article-title":"Serine-71 of the Glycoprotein Hef Is Located at the Active-Site of the Acetylesterase of Influenza-C Virus","volume":"102","author":"G Herrler","year":"1988","journal-title":"Archives of virology"},{"issue":";","key":"ref43","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1038\/nsmb.1840","article-title":"HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues","volume":"17","author":"T Krojer","year":"2010","journal-title":"Nature structural & molecular biology"},{"issue":"23","key":"ref44","doi-asserted-by":"crossref","first-page":"16645","DOI":"10.1074\/jbc.M112.438127","article-title":"Large lateral movement of transmembrane helix S5 is not required for substrate access to the active site of rhomboid intramembrane protease","volume":"288","author":"Y Xue","year":"2013","journal-title":"The Journal of biological chemistry"},{"key":"ref45","article-title":"Hemagglutinin-esterase-fusion (HEF) protein of influenza C virus","author":"M Wang","year":"2015","journal-title":"Protein Cell"},{"issue":"3","key":"ref46","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.celrep.2013.01.025","article-title":"Bat-derived influenza hemagglutinin H17 does not bind canonical avian or human receptors and most likely uses a unique entry mechanism","volume":"3","author":"X Sun","year":"2013","journal-title":"Cell reports"},{"issue":"10","key":"ref47","doi-asserted-by":"crossref","first-page":"e1003657","DOI":"10.1371\/journal.ppat.1003657","article-title":"New world bats harbor diverse influenza A viruses","volume":"9","author":"S Tong","year":"2013","journal-title":"PLoS Pathog"},{"issue":"2","key":"ref48","doi-asserted-by":"crossref","first-page":"171","DOI":"10.2105\/AJPH.39.2.171","article-title":"Studies on Survival of Influenza Virus Between Epidemics and Antigenic Variants of the Virus","volume":"39","author":"RM Taylor","year":"1949","journal-title":"Am J Public Health N"},{"issue":"2913","key":"ref49","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1126\/science.112.2913.495","article-title":"Identification of Another Epidemic Respiratory Disease","volume":"112","author":"T Francis","year":"1950","journal-title":"Science"},{"issue":"1","key":"ref50","first-page":"416","article-title":"Further Observations on the Jj and 1233 Influenza Viruses","volume":"10","author":"JJ Quilligan","year":"1951","journal-title":"Fed Proc"},{"issue":"20","key":"ref51","doi-asserted-by":"crossref","first-page":"11282","DOI":"10.1128\/JVI.00910-07","article-title":"Rescue of influenza c virus from recombinant DNA","volume":"81","author":"B Crescenzo-Chaigne","year":"2007","journal-title":"J Virol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.virol.2015.08.030","article-title":"Influenza D virus infection in Mississippi beef cattle","volume":"486","author":"L Ferguson","year":"2015","journal-title":"Virology"},{"issue":"13","key":"ref53","doi-asserted-by":"crossref","first-page":"7200","DOI":"10.1128\/JVI.00980-13","article-title":"Adaptation of Avian Influenza A Virus Polymerase in Mammals To Overcome the Host Species Barrier","volume":"87","author":"B Maenz","year":"2013","journal-title":"J Virol"},{"issue":"4","key":"ref54","first-page":"765","article-title":"Influenza virus proteins as factors involved in interspecies transmission","volume":"17","author":"IM Gora","year":"2014","journal-title":"Polish Journal of Veterinary Sciences"},{"issue":"5772","key":"ref55","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1126\/science.1122818","article-title":"Host species barriers to influenza virus infections","volume":"312","author":"T Kuiken","year":"2006","journal-title":"Science"},{"issue":"2","key":"ref56","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1750-2659.2007.00009.x","article-title":"Avian influenza and poultry workers, Peru, 2006","volume":"1","author":"EJ Ortiz","year":"2007","journal-title":"Influenza and other respiratory viruses"},{"issue":"4","key":"ref57","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1863-2378.2009.01231.x","article-title":"Evidence of Previous Avian Influenza Infection among US Turkey Workers","volume":"57","author":"G Kayali","year":"2010","journal-title":"Zoonoses Public Hlth"},{"issue":"23","key":"ref58","doi-asserted-by":"crossref","first-page":"12861","DOI":"10.1128\/JVI.01606-12","article-title":"Insights into avian influenza virus pathogenicity: the hemagglutinin precursor HA0 of subtype H16 has an alpha-helix structure in its cleavage site with inefficient HA1\/HA2 cleavage","volume":"86","author":"X Lu","year":"2012","journal-title":"Journal of virology"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0076-6879(97)76066-X","article-title":"Processing of X-ray diffraction data collected in oscillation mode","volume":"276","author":"Z Otwinowski","year":"1997","journal-title":"Method Enzymol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1107\/S0907444901012471","article-title":"Pushing the boundaries of molecular replacement with maximum likelihood","volume":"57","author":"RJ Read","year":"2001","journal-title":"Acta Crystallogr D"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1107\/S0907444994003112","article-title":"The Ccp4 Suite\u2014Programs for Protein Crystallography","volume":"50","author":"S Bailey","year":"1994","journal-title":"Acta Crystallographica Section D"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1107\/S0907444904019158","article-title":"Coot: model-building tools for molecular graphics","volume":"60","author":"P Emsley","year":"2004","journal-title":"Acta Crystallogr D"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1107\/S0907444996012255","article-title":"Refinement of macromolecular structures by the maximum-likelihood method","volume":"53","author":"GN Murshudov","year":"1997","journal-title":"Acta Crystallogr D"},{"issue":"2","key":"ref64","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1107\/S0907444909052925","article-title":"PHENIX: a comprehensive Python-based system for macromolecular structure solution","volume":"66","author":"PD Adams","year":"2010","journal-title":"Acta Crystallographica Section D"},{"issue":"4","key":"ref65","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/prot.340120407","article-title":"Stereochemical quality of protein-structure coordinates","volume":"12","author":"AL Morris","year":"1992","journal-title":"Proteins-Structure Function and Genetics"},{"key":"ref66","first-page":"3","article-title":"Animal Influenza Virus","volume":"1161","author":"M Killian","year":"2014"},{"issue":"1","key":"ref67","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002492","article-title":"The Murine Coronavirus Hemagglutinin-esterase Receptor-binding Site: A Major Shift in Ligand Specificity through Modest Changes in Architecture","volume":"8","author":"MA Langereis","year":"2012","journal-title":"Plos Pathog"},{"issue":"16","key":"ref68","doi-asserted-by":"crossref","first-page":"7782","DOI":"10.1073\/pnas.91.16.7782","article-title":"9-O-acetylated sialic acids have widespread but selective expression: analysis using a chimeric dual-function probe derived from influenza C hemagglutinin-esterase","volume":"91","author":"A Klein","year":"1994","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"26","key":"ref69","doi-asserted-by":"crossref","first-page":"10696","DOI":"10.1073\/pnas.1104306108","article-title":"Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor","volume":"108","author":"G Peng","year":"2011","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0076-6879(03)01074-7","article-title":"Recombinant influenza C hemagglutinin-esterase as a probe for sialic acid 9-O-acetylation","volume":"363","author":"LT Martin","year":"2003","journal-title":"Methods in enzymology"},{"issue":"1","key":"ref71","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/nbt1375","article-title":"Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin","volume":"26","author":"A Chandrasekaran","year":"2008","journal-title":"Nature biotechnology"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"5600","DOI":"10.1038\/ncomms6600","article-title":"Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus","volume":"6","author":"M Wang","year":"2015","journal-title":"Nature communications"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"W320","DOI":"10.1093\/nar\/gku316","article-title":"Deciphering key features in protein structures with the new ENDscript server","volume":"42","author":"X Robert","year":"2014","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"ref74","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1093\/bioinformatics\/bts199","article-title":"Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data","volume":"28","author":"M Kearse","year":"2012","journal-title":"Bioinformatics"}],"updated-by":[{"DOI":"10.1371\/journal.ppat.1005505","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2016,3,8]],"date-time":"2016-03-08T00:00:00Z","timestamp":1457395200000}}],"container-title":["PLOS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1005411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T11:01:14Z","timestamp":1654167674000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1005411"}},"subtitle":[],"editor":[{"given":"F\u00e9lix A.","family":"Rey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,1,27]]},"references-count":74,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,1,27]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1005411","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,27]]}}}