{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:54:35Z","timestamp":1791312875866,"version":"4.3.1"},"reference-count":70,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2016,10,24]],"date-time":"2016-10-24T00:00:00Z","timestamp":1477267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Deutsche Forschungsgemeinschaft (DE)","award":["SFB796, C6"],"award-info":[{"award-number":["SFB796, C6"]}]},{"name":"Deutsche Forschungsgemeinschaft (DE)","award":["SFB796, A4"],"award-info":[{"award-number":["SFB796, A4"]}]},{"name":"FWO-Flanders"},{"name":"BOF\/GOA"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1005916","type":"journal-article","created":{"date-parts":[[2016,10,24]],"date-time":"2016-10-24T17:42:35Z","timestamp":1477330955000},"page":"e1005916","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":38,"title":["The Tax-Inducible Actin-Bundling Protein Fascin Is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1)"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2643-5849","authenticated-orcid":true,"given":"Christine","family":"Gross","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veit","family":"Wiesmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Millen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Kalmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Wittenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Gettemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea K.","family":"Thoma-Kress","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,10,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3389\/fmicb.2012.00388","article-title":"Epidemiological Aspects and World Distribution of HTLV-1 Infection","volume":"3","author":"A Gessain","year":"2012","journal-title":"Front Microbiol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"7415","DOI":"10.1073\/pnas.77.12.7415","article-title":"Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma","volume":"77","author":"BJ Poiesz","year":"1980","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1073\/pnas.79.6.2031","article-title":"Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease","volume":"79","author":"M Yoshida","year":"1982","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1073\/pnas.81.8.2534","article-title":"Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease","volume":"81","author":"M Yoshida","year":"1984","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0140-6736(85)92734-5","article-title":"Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis","volume":"2","author":"A Gessain","year":"1985","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/S0140-6736(86)91298-5","article-title":"HTLV-I associated myelopathy, a new clinical entity","volume":"1","author":"M Osame","year":"1986","journal-title":"Lancet"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/nrc2111","article-title":"Human T-cell leukemia virus type 1 (HTLV-1) infectivity and cellular transformation","volume":"7","author":"M Matsuoka","year":"2007","journal-title":"Nat Rev Cancer"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S1473-3099(07)70081-6","article-title":"Human T-lymphotropic virus 1: recent knowledge about an ancient infection","volume":"7","author":"K Verdonck","year":"2007","journal-title":"Lancet Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"378","DOI":"10.3389\/fmicb.2012.00378","article-title":"Pathways of cell-cell transmission of HTLV-1","volume":"3","author":"C Pique","year":"2012","journal-title":"Front Microbiol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0092-8674(03)00881-X","article-title":"The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV","volume":"115","author":"N Manel","year":"2003","journal-title":"Cell"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"5176","DOI":"10.1182\/blood-2008-04-150342","article-title":"HTLV-1 uses HSPG and neuropilin-1 for entry by molecular mimicry of VEGF165","volume":"113","author":"S Lambert","year":"2009","journal-title":"Blood"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"12692","DOI":"10.1128\/JVI.79.20.12692-12702.2005","article-title":"Heparan sulfate proteoglycans mediate attachment and entry of human T-cell leukemia virus type 1 virions into CD4+ T cells","volume":"79","author":"KS Jones","year":"2005","journal-title":"J Virol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"406","DOI":"10.3389\/fmicb.2012.00406","article-title":"HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways","volume":"3","author":"R Currer","year":"2012","journal-title":"Front Microbiol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1128\/JVI.69.5.2863-2868.1995","article-title":"Clonal expansion of human T-cell leukemia virus type I-infected cells in asymptomatic and symptomatic carriers without malignancy","volume":"69","author":"E Wattel","year":"1995","journal-title":"J Virol"},{"key":"ref15","first-page":"4862","article-title":"Persistent clonal proliferation of human T-lymphotropic virus type I-infected cells in vivo","volume":"57","author":"K Etoh","year":"1997","journal-title":"Cancer Res"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.3390\/v7072793","article-title":"Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence","volume":"7","author":"A Carpentier","year":"2015","journal-title":"Viruses"},{"key":"ref17","doi-asserted-by":"crossref","DOI":"10.3390\/v8030074","article-title":"Molecular Mechanisms of HTLV-1 Cell-to-Cell Transmission","volume":"8","author":"C Gross","year":"2016","journal-title":"Viruses"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1128\/JCM.30.4.905-910.1992","article-title":"Infection of peripheral blood mononuclear cells and cell lines by cell-free human T-cell lymphoma\/leukemia virus type I","volume":"30","author":"N Fan","year":"1992","journal-title":"J Clin Microbiol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"8461","DOI":"10.1128\/JVI.75.18.8461-8468.2001","article-title":"Examining human T-lymphotropic virus type 1 infection and replication by cell-free infection with recombinant virus vectors","volume":"75","author":"D Derse","year":"2001","journal-title":"J Virol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1002\/jmv.24264","article-title":"HTLV-1 viral RNA is detected rarely in plasma of HTLV-1 infected subjects","volume":"87","author":"MA Demontis","year":"2015","journal-title":"J Med Virol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1126\/science.1080115","article-title":"Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton","volume":"299","author":"T Igakura","year":"2003","journal-title":"Science"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"20738","DOI":"10.1073\/pnas.1009635107","article-title":"Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission","volume":"107","author":"N. Van Prooyen","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.3390\/v2071427","article-title":"The HTLV-1 Virological Synapse","volume":"2","author":"M Nejmeddine","year":"2010","journal-title":"Viruses"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/nm.2065","article-title":"Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses","volume":"16","author":"AM Pais-Correia","year":"2010","journal-title":"Nat Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"e1000788","DOI":"10.1371\/journal.ppat.1000788","article-title":"Quantitative comparison of HTLV-1 and HIV-1 cell-to-cell infection with new replication dependent vectors","volume":"6","author":"D Mazurov","year":"2010","journal-title":"PLoS Pathog"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1182\/blood-2008-03-136770","article-title":"HTLV-1-Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse","volume":"114","author":"M Nejmeddine","year":"2009","journal-title":"Blood"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/ijc.2910520316","article-title":"Strong induction of ICAM-1 in human T cells transformed by human T-cell-leukemia virus type 1 and depression of ICAM-1 or LFA-1 in adult T-cell-leukemia-derived cell lines","volume":"52","author":"K Fukudome","year":"1992","journal-title":"Int J Cancer"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"e1003917","DOI":"10.1371\/journal.ppat.1003917","article-title":"Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission","volume":"10","author":"SA Chevalier","year":"2014","journal-title":"PLoS Pathog"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"3609","DOI":"10.1182\/blood-2010-09-305805","article-title":"The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF-kappaB signals","volume":"117","author":"AK Kress","year":"2011","journal-title":"Blood"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/path.2894","article-title":"The roles of fascins in health and disease","volume":"224","author":"Y Hashimoto","year":"2011","journal-title":"J Pathol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"4601","DOI":"10.1242\/jcs.175760","article-title":"A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration","volume":"128","author":"G Villari","year":"2015","journal-title":"J Cell Sci"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"4288","DOI":"10.1182\/blood-2006-08-043422","article-title":"Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin","volume":"109","author":"R Geyeregger","year":"2007","journal-title":"Blood"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.tcm.2004.06.002","article-title":"Fascin protrusions in cell interactions","volume":"14","author":"JC Adams","year":"2004","journal-title":"Trends Cardiovasc Med"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.virol.2015.08.025","article-title":"Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism","volume":"485","author":"CF Mohr","year":"2015","journal-title":"Virology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/ijc.2910190505","article-title":"Characterization of EBV-genome negative &quot;null&quot; and &quot;T&quot; cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma","volume":"19","author":"U Schneider","year":"1977","journal-title":"Int J Cancer"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1128\/JVI.01970-06","article-title":"CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1","volume":"81","author":"JH Wang","year":"2007","journal-title":"J Virol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1182\/blood.V55.3.409.409","article-title":"Mitogen requirements for the in vitro propagation of cutaneous T-cell lymphomas","volume":"55","author":"AF Gazdar","year":"1980","journal-title":"Blood"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1006\/viro.1999.9909","article-title":"Defective and wild-type human T-cell leukemia virus type I proviruses: characterization of gene products and trans-interactions between proviruses","volume":"262","author":"M Shuh","year":"1999","journal-title":"Virology"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/1742-4690-6-83","article-title":"Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2","volume":"6","author":"T Shoji","year":"2009","journal-title":"Retrovirology"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"18974","DOI":"10.1073\/pnas.0506659103","article-title":"Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoprotein","volume":"102","author":"JM Peloponese Jr.","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1182\/blood-2007-05-092288","article-title":"The viral interferon-regulatory factor-3 is required for the survival of KSHV-infected primary effusion lymphoma cells","volume":"111","author":"E Wies","year":"2008","journal-title":"Blood"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s12964-014-0046-x","article-title":"The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-kappaB in lymphocytes and contributes to their invasive migration","volume":"12","author":"CF Mohr","year":"2014","journal-title":"Cell Commun Signal"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1096\/fj.13-242537","article-title":"Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization","volume":"28","author":"I Van Audenhove","year":"2014","journal-title":"FASEB J"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.virol.2014.06.028","article-title":"The transcription elongation factor ELL2 is specifically upregulated in HTLV-1-infected T-cells and is dependent on the viral oncoprotein Tax","volume":"464\u2013465","author":"MC Mann","year":"2014","journal-title":"Virology"},{"key":"ref45","first-page":"295","article-title":"Development and characterization of monoclonal antibodies to the HTLV-I Tax (P40X) protein","volume":"8","author":"B Langton","year":"1988","journal-title":"Med Virol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"4741","DOI":"10.1182\/blood-2007-10-115220","article-title":"Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1-infected cultured and patients&apos; T cells by the viral Tax oncoprotein","volume":"111","author":"K Pichler","year":"2008","journal-title":"Blood"},{"key":"ref47","first-page":"122","article-title":"Bildverarbeitung f\u00fcr die Medizin 2016","author":"V Wiesmann","year":"2016"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/BF00133570","article-title":"Snakes: Active contour models","volume":"4","author":"M Kass","year":"1988","journal-title":"Int J Comput Vision"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"6097","DOI":"10.1128\/JVI.06570-11","article-title":"APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1","volume":"86","author":"M Ooms","year":"2012","journal-title":"J Virol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.virol.2005.05.012","article-title":"A new sensitive and quantitative HTLV-I-mediated cell fusion assay in T cells","volume":"338","author":"ME Pare","year":"2005","journal-title":"Virology"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"22284","DOI":"10.1074\/jbc.M114.549659","article-title":"Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein","volume":"289","author":"E Jaworski","year":"2014","journal-title":"J Biol Chem"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.3390\/v3081439","article-title":"Cell surface markers in HTLV-1 pathogenesis","volume":"3","author":"AK Kress","year":"2011","journal-title":"Viruses"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1128\/JVI.06993-11","article-title":"Role of O-glycosylation and expression of CD43 and CD45 on the surfaces of effector T cells in human T cell leukemia virus type 1 cell-to-cell infection","volume":"86","author":"D Mazurov","year":"2012","journal-title":"J Virol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"254","DOI":"10.3390\/v3030254","article-title":"A new role for the HTLV-1 p8 protein: increasing intercellular conduits and viral cell-to-cell transmission","volume":"3","author":"M Malbec","year":"2011","journal-title":"Viruses"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"10591","DOI":"10.1128\/JVI.01940-15","article-title":"Improvement of HIV-1 and Human T Cell Lymphotropic Virus Type 1 Replication-Dependent Vectors via Optimization of Reporter Gene Reconstitution and Modification with Intronic Short Hairpin RNA","volume":"89","author":"A Shunaeva","year":"2015","journal-title":"J Virol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"9148","DOI":"10.1074\/jbc.M115.706937","article-title":"Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia","volume":"291","author":"I Van Audenhove","year":"2016","journal-title":"J Biol Chem"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"29653","DOI":"10.1074\/jbc.M502639200","article-title":"Human T-lymphotropic virus, type 1, tax protein triggers microtubule reorientation in the virological synapse","volume":"280","author":"M Nejmeddine","year":"2005","journal-title":"J Biol Chem"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3390\/v3040293","article-title":"How HIV takes advantage of the cytoskeleton in entry and replication","volume":"3","author":"B Stolp","year":"2011","journal-title":"Viruses"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"4415","DOI":"10.1128\/JVI.79.7.4415-4424.2005","article-title":"Epstein-Barr virus transforming protein LMP1 plays a critical role in virus production","volume":"79","author":"N Ahsan","year":"2005","journal-title":"J Virol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"9285","DOI":"10.1128\/JVI.00712-12","article-title":"Roles of cell signaling pathways in cell-to-cell contact-mediated Epstein-Barr virus transmission","volume":"86","author":"A Nanbo","year":"2012","journal-title":"J Virol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/1742-4690-5-76","article-title":"The HTLV-1 Tax interactome","volume":"5","author":"M Boxus","year":"2008","journal-title":"Retrovirology"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1074\/jbc.M310069200","article-title":"Protein profile of tax-associated complexes","volume":"279","author":"K Wu","year":"2004","journal-title":"J Biol Chem"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.4049\/jimmunol.1101562","article-title":"Human T lymphotropic virus type 1 increases T lymphocyte migration by recruiting the cytoskeleton organizer CRMP2","volume":"188","author":"M Varrin-Doyer","year":"2012","journal-title":"J Immunol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ncb1544","article-title":"Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission","volume":"9","author":"NM Sherer","year":"2007","journal-title":"Nat Cell Biol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/ncb1682","article-title":"Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission","volume":"10","author":"S Sowinski","year":"2008","journal-title":"Nat Cell Biol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s13577-016-0136-8","article-title":"The diversity of the structure and genomic integration sites of HTLV-1 provirus in MT-2 cell lines","volume":"29","author":"Y Hashikura","year":"2016","journal-title":"Hum Cell"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1182\/blood-2010-05-284141","article-title":"Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits","volume":"116","author":"VW Valeri","year":"2010","journal-title":"Blood"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/nm1745","article-title":"Cell-free HTLV-1 infects dendritic cells leading to transmission and transformation of CD4(+) T cells","volume":"14","author":"KS Jones","year":"2008","journal-title":"Nat Med"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"10580","DOI":"10.1128\/JVI.01799-15","article-title":"Viral Source-Independent High Susceptibility of Dendritic Cells to Human T-Cell Leukemia Virus Type 1 Infection Compared to That of T Lymphocytes","volume":"89","author":"S Alais","year":"2015","journal-title":"J Virol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.4049\/jimmunol.171.4.1825","article-title":"The human fascin gene promoter is highly active in mature dendritic cells due to a stage-specific enhancer","volume":"171","author":"M Bros","year":"2003","journal-title":"J Immunol"}],"container-title":["PLOS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1005916","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T22:13:06Z","timestamp":1601158386000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1005916"}},"subtitle":[],"editor":[{"given":"David T.","family":"Evans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,10,24]]},"references-count":70,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2016,10,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1005916","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,24]]}}}