{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T18:03:26Z","timestamp":1788545006605,"version":"build-2803163510"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T00:00:00Z","timestamp":1484784000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"WHO Polio Research Committee","award":["I8-TSA-043 & I8-TSA-083"],"award-info":[{"award-number":["I8-TSA-043 & I8-TSA-083"]}]}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1006117","type":"journal-article","created":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T18:37:01Z","timestamp":1484851021000},"page":"e1006117","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":63,"title":["Genetically Thermo-Stabilised, Immunogenic Poliovirus Empty Capsids; a Strategy for Non-replicating Vaccines"],"prefix":"10.1371","volume":"13","author":[{"given":"Helen","family":"Fox","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5400-1899","authenticated-orcid":true,"given":"Sarah","family":"Knowlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip D.","family":"Minor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8687-1573","authenticated-orcid":true,"given":"Andrew J.","family":"Macadam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,1,19]]},"reference":[{"key":"ref1","unstructured":"WHO; <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.polioeradication.org\/Dataandmonitoring\/Poliothisweek.aspx\" xlink:type=\"simple\">http:\/\/www.polioeradication.org\/Dataandmonitoring\/Poliothisweek.aspx<\/ext-link> (Accessed July 28 2016)."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1099\/vir.0.036988-0","article-title":"The polio eradication programme and issues of the endgame","volume":"93","author":"PD Minor","year":"2012","journal-title":"J Gen Virol"},{"issue":"8","key":"ref3","doi-asserted-by":"crossref","first-page":"e1005114","DOI":"10.1371\/journal.ppat.1005114","article-title":"Twenty-eight years of poliovirus replication in an immunodeficient individual: impact on the global polio eradication initiative","volume":"11","author":"G Dunn","year":"2015","journal-title":"PLoS Pathog"},{"key":"ref4","article-title":"Global action plan to minimize poliovirus facility-associated risk after type-specific eradication of wild polioviruses and sequential cessation of OPV use","year":"2014"},{"key":"ref5","article-title":"Polio eradication and end game strategic plan","year":"2014"},{"issue":"16","key":"ref6","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1016\/j.vaccine.2014.11.015","article-title":"Development and introduction of inactivated poliovirus vaccines derived from Sabin strains in Japan","volume":"34","author":"H Shimizu","year":"2016","journal-title":"Vaccine"},{"issue":"12","key":"ref7","doi-asserted-by":"crossref","first-page":"e1005316","DOI":"10.1371\/journal.ppat.1005316","article-title":"New Strains Intended for the Production of Inactivated Polio Vaccine at Low-Containment After Eradication","volume":"11","author":"S Knowlson","year":"2015","journal-title":"PLoS Pathog"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1099\/vir.0.19088-0","article-title":"Characterization of formaldehyde-inactivated poliovirus preparations made from live-attenuated strains","volume":"84","author":"J Martin","year":"2003","journal-title":"J.Gen.Virol"},{"issue":"5","key":"ref9","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1002\/j.1460-2075.1989.tb03541.x","article-title":"Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus","volume":"8","author":"DJ Filman","year":"1989","journal-title":"EMBO J"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"5225","DOI":"10.1128\/JVI.65.10.5225-5231.1991","article-title":"An assembly defect as a result of an attenuating mutation in the capsid proteins of the poliovirus type 3 vaccine strain","volume":"65","author":"A J Macadam","year":"1991","journal-title":"J.Virol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1099\/0022-1317-70-5-1117","article-title":"The temperature sensitivity of the Sabin type 3 vaccine strain of poliovirus: molecular and structural effects of a mutation in the capsid protein VP3","volume":"70","author":"PD Minor","year":"1989","journal-title":"J.Gen.Virol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0092-1157(89)90004-8","article-title":"Quantitation of poliovirus antigens in inactivated viral vaccines by enzyme-linked immunosorbent assay using animal sera and monoclonal antibodies","volume":"17","author":"C Singer","year":"1989","journal-title":"J. Biol. Stand"},{"key":"ref13","first-page":"119","article-title":"Potency testing of killed polio vaccine in rats","volume":"47","author":"G van Steenis","year":"1981","journal-title":"Dev Biol Stand"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1099\/0022-1317-67-7-1283","article-title":"Antigenic structure of polioviruses of serotypes 1, 2 and 3","volume":"67","author":"PD Minor","year":"1986","journal-title":"J.Gen.Virol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1099\/0022-1317-70-6-1453","article-title":"Synthesis of immunogenic, but non-infectious, poliovirus particles in insect cells by a baculovirus expression vector","volume":"70","author":"T Urakawa","year":"1989","journal-title":"J.Gen.Virol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1099\/0022-1317-78-8-1829","article-title":"Immunogenic, non-infectious polio subviral particles synthesized in <italic>Saccharomyces cerevisiae<\/italic>","volume":"78","author":"B Rombaut","year":"1997","journal-title":"J.Gen.Virol"},{"issue":"4720","key":"ref17","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1126\/science.2994218","article-title":"Three-dimensional structure of poliovirus at 2.9 A resolution","volume":"229","author":"JM Hogle","year":"1985","journal-title":"Science"},{"issue":"7","key":"ref18","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/S0969-2126(97)00249-9","article-title":"Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes","volume":"5","author":"KN Lentz","year":"1997","journal-title":"Structure"},{"issue":"8","key":"ref19","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1128\/JVI.03101-14","article-title":"Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry","volume":"89","author":"M Strauss","year":"2015","journal-title":"J Virol"},{"key":"ref20","article-title":"Recommendations to assure the quality, safety and efficacy of poliomyelitis vaccines inactivated)","year":"2014"},{"issue":"5","key":"ref21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.vaccine.2004.07.046","article-title":"Efficacy and other milestones for human papillomavirus vaccine introduction","volume":"23","author":"SR Pagliusi","year":"2004","journal-title":"Vaccine"},{"issue":"1\u20132","key":"ref22","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF01309297","article-title":"Molecular cloning of the genomes of poliovirus type 3 strains by the cDNA: RNA hybrid method","volume":"81","author":"G Stanway","year":"1984","journal-title":"Arch Virol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1073\/pnas.83.8.2330","article-title":"Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase","volume":"83","author":"S van der Werf","year":"1986","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"ref24","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0042-6822(85)90389-7","article-title":"Induction by synthetic peptides of broadly reactive, type-specific neutralizing antibody to poliovirus type 3","volume":"143","author":"M Ferguson","year":"1985","journal-title":"Virology"},{"key":"ref25","first-page":"23","article-title":"Establishment of European Pharmacopoeia BRP batch 2 for inactivated poliomyelitis vaccine for in vitro D antigen assay","volume":"1","author":"F Fuchs","year":"2003","journal-title":"Pharmeuropa Bio"},{"issue":"30","key":"ref26","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1016\/j.vaccine.2015.05.052","article-title":"High resolution identity testing of inactivated poliovirus vaccines","volume":"33","author":"ET Mee","year":"2015","journal-title":"Vaccine"}],"container-title":["PLOS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1006117","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T05:01:08Z","timestamp":1601355668000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1006117"}},"subtitle":[],"editor":[{"given":"Bert L.","family":"Semler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,1,19]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1006117","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,19]]}}}