{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:19:48Z","timestamp":1790817588426,"version":"4.1.0"},"update-to":[{"DOI":"10.1371\/journal.ppat.1007647","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000}}],"reference-count":82,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T00:00:00Z","timestamp":1553040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-13-JSV7-0009"],"award-info":[{"award-number":["ANR-13-JSV7-0009"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1007647","type":"journal-article","created":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T14:36:18Z","timestamp":1553092578000},"page":"e1007647","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":30,"title":["Sympatric versus allopatric evolutionary contexts shape differential immune response in Biomphalaria \/ Schistosoma interaction"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7592-0432","authenticated-orcid":true,"given":"Ana\u00efs","family":"Portet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9541-3611","authenticated-orcid":true,"given":"Silvain","family":"Pinaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5162-349X","authenticated-orcid":true,"given":"Cristian","family":"Chaparro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4180-9303","authenticated-orcid":true,"given":"Richard","family":"Galinier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3675-5013","authenticated-orcid":true,"given":"Nolwenn M.","family":"Dheilly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Portela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4796-1488","authenticated-orcid":true,"given":"Guillaume M.","family":"Charriere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Allienne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6933-3354","authenticated-orcid":true,"given":"David","family":"Duval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2097-2563","authenticated-orcid":true,"given":"Benjamin","family":"Gourbal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,3,20]]},"reference":[{"key":"ref1","article-title":"Schistosomiasis Fact Sheet No 115","year":"2010"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0014-4894(76)90022-9","article-title":"Intermediate host specificity in Schistosoma mansoni","volume":"39","author":"PF Basch","year":"1976","journal-title":"Experimental Parasitology"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/expr.1996.4106","article-title":"Schistosoma mansoni: distribution patterns of miracidia among Biomphalaria glabrata snail as related to host susceptibility and sporocyst regulatory processes","volume":"85","author":"A Theron","year":"1997","journal-title":"Experimental Parasitology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.meegid.2014.04.025","article-title":"Multi-parasite host susceptibility and multi-host parasite infectivity: a new approach of the Biomphalaria glabrata\/Schistosoma mansoni compatibility polymorphism","volume":"26","author":"A Theron","year":"2014","journal-title":"Infection Genetics and Evolution"},{"issue":"Pt 3","key":"ref5","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1017\/S0031182006000412","article-title":"Geographical variations in infectivity and susceptibility in the host-parasite system Schistosoma mansoni\/Biomphalaria glabrata: no evidence for local adaptation","volume":"133","author":"F Prugnolle","year":"2006","journal-title":"Parasitology"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1017\/S0031182000049696","article-title":"Genetic factors in susceptibility of Biomphalaria glabrata for different strains of Schistosoma mansoni","volume":"70","author":"CS Richards","year":"1975","journal-title":"Parasitology"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dci.2011.09.002","article-title":"Compatibility polymorphism in snail\/schistosome interactions: From field to theory to molecular mechanisms","volume":"37","author":"G Mitta","year":"2012","journal-title":"Dev Comp Immunol"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"e0005398","DOI":"10.1371\/journal.pntd.0005398","article-title":"A multistrain approach to studying the mechanisms underlying compatibility in the interaction between Biomphalaria glabrata and Schistosoma mansoni","volume":"11","author":"R Galinier","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/bs.apar.2016.08.006","article-title":"The Compatibility Between Biomphalaria glabrata Snails and Schistosoma mansoni: An Increasingly Complex Puzzle","volume":"97","author":"G Mitta","year":"2017","journal-title":"Adv Parasitol"},{"issue":"6","key":"ref10","doi-asserted-by":"crossref","first-page":"e1701","DOI":"10.1371\/journal.pntd.0001701","article-title":"Effects of Cu\/Zn superoxide dismutase (sod1) genotype and genetic background on growth, reproduction and defense in Biomphalaria glabrata","volume":"6","author":"KM Bonner","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.molbiopara.2006.02.009","article-title":"Biomphalaria glabrata cytosolic copper\/zinc superoxide dismutase (SOD1) gene: association of SOD1 alleles with resistance\/susceptibility to Schistosoma mansoni","volume":"147","author":"CP Goodall","year":"2006","journal-title":"Mol Biochem Parasitol"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"e1005067","DOI":"10.1371\/journal.pgen.1005067","article-title":"Hyperdiverse gene cluster in snail host conveys resistance to human schistosome parasites","volume":"11","author":"JA Tennessen","year":"2015","journal-title":"PLoS genetics"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.molbiopara.2009.09.009","article-title":"Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni","volume":"169","author":"W Ittiprasert","year":"2010","journal-title":"Molecular and Biochemical Parasitology"},{"issue":"12","key":"ref14","doi-asserted-by":"crossref","first-page":"e51102","DOI":"10.1371\/journal.pone.0051102","article-title":"Early differential gene expression in haemocytes from resistant and susceptible Biomphalaria glabrata strains in response to Schistosoma mansoni","volume":"7","author":"AE Lockyer","year":"2012","journal-title":"PloS one"},{"issue":"1\u20132","key":"ref15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.exppara.2004.04.004","article-title":"Schistosoma mansoni: resistant specific infection-induced gene expression in Biomphalaria glabrata identified by fluorescent-based differential display","volume":"107","author":"AE Lockyer","year":"2004","journal-title":"Experimental Parasitology"},{"issue":"8","key":"ref16","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.dci.2006.11.004","article-title":"Biomphalaria glabrata transcriptome: identification of cell-signalling, transcriptional control and immune-related genes from open reading frame expressed sequence tags (ORESTES)","volume":"31","author":"AE Lockyer","year":"2007","journal-title":"Developmental and Comparative Immunology"},{"issue":"11","key":"ref17","doi-asserted-by":"crossref","first-page":"e330","DOI":"10.1371\/journal.pntd.0000330","article-title":"Controlled Chaos of Polymorphic Mucins in a Metazoan Parasite (Schistosoma mansoni) Interacting with Its Invertebrate Host (Biomphalaria glabrata)","volume":"2","author":"E Roger","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"e1003216","DOI":"10.1371\/journal.ppat.1003216","article-title":"Biomphalysin, a New beta Pore-forming Toxin Involved in Biomphalaria glabrata Immune Defense against Schistosoma mansoni","volume":"9","author":"R Galinier","year":"2013","journal-title":"PLoS Pathog"},{"issue":"4","key":"ref19","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1645\/0022-3395(2001)087[0778:IONOIK]2.0.CO;2","article-title":"Involvement of nitric oxide in killing of Schistosoma mansoni sporocysts by hemocytes from resistant Biomphalaria glabrata","volume":"87","author":"UK Hahn","year":"2001","journal-title":"Journal of Parasitology"},{"issue":"9","key":"ref20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0000813","article-title":"A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host\/parasite model","volume":"4","author":"Y Mone","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"ref21","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1645\/GE-1410.1","article-title":"Differences in cysteine protease activity in Schistosoma mansoni-resistant and -susceptible Biomphalaria glabrata and characterization of the hepatopancreas cathepsin B Full-length cDNA","volume":"94","author":"J Myers","year":"2008","journal-title":"Journal of Parasitology"},{"issue":"19","key":"ref22","doi-asserted-by":"crossref","first-page":"5305","DOI":"10.1073\/pnas.1521239113","article-title":"Endogenous growth factor stimulation of hemocyte proliferation induces resistance to Schistosoma mansoni challenge in the snail host","volume":"113","author":"EA Pila","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"ref23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.molbiopara.2007.11.003","article-title":"Molecular determinants of compatibility polymorphism in the Biomphalaria glabrata\/Schistosoma mansoni model: New candidates identified by a global comparative proteomics approach","volume":"157","author":"E Roger","year":"2008","journal-title":"Mol Biochem Parasitol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/978-1-4899-8032-8_12","article-title":"The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer","volume":"773","author":"JM Bridger","year":"2014","journal-title":"Adv Exp Med Biol"},{"issue":"4","key":"ref25","doi-asserted-by":"crossref","first-page":"e1002677","DOI":"10.1371\/journal.ppat.1002677","article-title":"Reversing the resistance phenotype of the Biomphalaria glabrata snail host Schistosoma mansoni infection by temperature modulation","volume":"8","author":"W Ittiprasert","year":"2012","journal-title":"PLoS pathogens"},{"issue":"3","key":"ref26","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.exppara.2009.07.015","article-title":"Schistosoma mansoni infection of juvenile Biomphalaria glabrata induces a differential stress response between resistant and susceptible snails","volume":"123","author":"W Ittiprasert","year":"2009","journal-title":"Experimental Parasitology"},{"issue":"2","key":"ref27","article-title":"Susceptibility of Snails to Infection with Schistosomes is influenced by Temperature and Expression of Heat Shock Proteins","volume":"5","author":"M Knight","year":"2015","journal-title":"Epidemiology"},{"key":"ref28","article-title":"Effects of abnormal temperature and starvation on the internal defense system of the schistosome-transmitting snail Biomphalaria glabrata","author":"MK Nelson","year":"2016","journal-title":"J Invertebr Pathol"},{"issue":"8","key":"ref29","doi-asserted-by":"crossref","first-page":"e1003571","DOI":"10.1371\/journal.ppat.1003571","article-title":"Schistosoma mansoni mucin gene (SmPoMuc) expression: epigenetic control to shape adaptation to a new host","volume":"9","author":"C Perrin","year":"2012","journal-title":"PLoS pathogens"},{"key":"ref30","article-title":"Integrated multi-omic analyses in Biomphalaria-Schistosoma dialogue reveal the immunobiological significance of FREP-SmPoMuc interaction","author":"A Portet","year":"2017","journal-title":"Developmental and comparative immunology"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1086\/679734","article-title":"Evolution of pathogen virulence across space during an epidemic","volume":"185","author":"EE Osnas","year":"2015","journal-title":"Am Nat"},{"issue":"10","key":"ref32","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1111\/j.1420-9101.2012.02588.x","article-title":"Variation in infectivity and aggressiveness in space and time in wild host-pathogen systems: causes and consequences","volume":"25","author":"AJ Tack","year":"2012","journal-title":"J Evol Biol"},{"issue":"1","key":"ref33","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1086\/419267","article-title":"Models of parasite virulence","volume":"71","author":"SA Frank","year":"1996","journal-title":"The Quarterly review of biology"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1111\/j.1461-0248.2004.00684.x","article-title":"Conceptual issues in local adaptation","volume":"7","author":"T Kawecki","year":"2004","journal-title":"Ecology letters"},{"issue":"1","key":"ref35","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s13071-016-1419-3","article-title":"Reciprocal cross infection of sticklebacks with the diphyllobothriidean cestode Schistocephalus solidus reveals consistent population differences in parasite growth and host resistance","volume":"9","author":"M Kalbe","year":"2016","journal-title":"Parasites & vectors"},{"issue":"5393","key":"ref36","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1126\/science.265.5175.1084","article-title":"Virulence and local adaptation of horizontally transmitted parasite","volume":"265","author":"D Ebert","year":"1994","journal-title":"Science"},{"issue":"8","key":"ref37","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1111\/j.1558-5646.1989.tb02616.x","article-title":"Adaptation by a Parasitic Trematode to Local Populations of Its Snail Host","volume":"43","author":"CM Lively","year":"1989","journal-title":"Evolution"},{"issue":"1366","key":"ref38","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1098\/rspb.1996.0019","article-title":"Parasite-host coevolution and geographic patterns of parasite infectivity and host susceptibility","volume":"263","author":"S Morand","year":"1996","journal-title":"Proc Biol Sci"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1186\/s13071-014-0533-3","article-title":"Field-derived Schistosoma mansoni and Biomphalaria pfeifferi in Kenya: a compatible association characterized by lack of strong local adaptation, and presence of some snails able to persistently produce cercariae for over a year","volume":"7","author":"MW Mutuku","year":"2014","journal-title":"Parasites & vectors"},{"issue":"Pt 2","key":"ref40","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1017\/S0031182003004360","article-title":"Parasite dose, prevalence of infection and local adaptation in a host-parasite system","volume":"128","author":"EE Osnas","year":"2004","journal-title":"Parasitology"},{"issue":"7","key":"ref41","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.ijpara.2011.01.007","article-title":"An example of molecular co-evolution: reactive oxygen species (ROS) and ROS scavenger levels in Schistosoma mansoni\/Biomphalaria glabrata interactions","volume":"41","author":"Y Mone","year":"2011","journal-title":"International journal for parasitology"},{"issue":"1","key":"ref42","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/eva.12294","article-title":"Understanding the ecology and evolution of host-parasite interactions across scales","volume":"9","author":"RM Penczykowski","year":"2015","journal-title":"Evolutionary applications"},{"issue":"1","key":"ref43","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.dci.2014.10.009","article-title":"A family of variable immunoglobulin and lectin domain containing molecules in the snail Biomphalaria glabrata","volume":"48","author":"NM Dheilly","year":"2015","journal-title":"Dev Comp Immunol"},{"issue":"1","key":"ref44","doi-asserted-by":"crossref","first-page":"e1005361","DOI":"10.1371\/journal.ppat.1005361","article-title":"A Shift from Cellular to Humoral Responses Contributes to Innate Immune Memory in the Vector Snail Biomphalaria glabrata","volume":"12","author":"S Pinaud","year":"2016","journal-title":"PLoS pathogens"},{"issue":"9","key":"ref45","doi-asserted-by":"crossref","first-page":"e1001115","DOI":"10.1371\/journal.ppat.1001115","article-title":"Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni","volume":"6","author":"A Baeza Garcia","year":"2010","journal-title":"PLoS pathogens"},{"key":"ref46","article-title":"Excretory-secretory proteome of larval Schistosoma mansoni and Echinostoma caproni, two parasites of Biomphalaria glabrata","author":"F Guillou","year":"2007","journal-title":"Molecular and biochemical parasitology"},{"issue":"1","key":"ref47","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.it.2012.08.002","article-title":"Calreticulin in the immune system: ins and outs","volume":"34","author":"M Raghavan","year":"2013","journal-title":"Trends in immunology"},{"issue":"4","key":"ref48","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1517\/14728220902832705","article-title":"Targeting major vault protein in senescence-associated apoptosis resistance","volume":"13","author":"SJ Ryu","year":"2009","journal-title":"Expert Opinion on Therapeutic Targets"},{"issue":"Pt 1","key":"ref49","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1042\/bj3520049","article-title":"Polydom: a secreted protein with pentraxin, complement control protein, epidermal growth factor and von Willebrand factor A domains","volume":"352","author":"D Gilges","year":"2000","journal-title":"Biochemical Journal"},{"issue":"11","key":"ref50","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1091\/mbc.e12-11-0789","article-title":"Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes","volume":"24","author":"M Bohdanowicz","year":"2013","journal-title":"Molecular Biology of the Cell"},{"issue":"1","key":"ref51","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.advenzreg.2009.01.005","article-title":"Phosphatidic acid phosphohydrolase in the regulation of inflammatory signaling","volume":"49","author":"A Grkovich","year":"2009","journal-title":"Advances in Enzyme Regulation"},{"issue":"10","key":"ref52","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0169-5347(03)00223-4","article-title":"Parasite local adaptation: Red Queen versus suicide king","volume":"18","author":"MF Dybdahl","year":"2003","journal-title":"TRENDs in Ecology and Evolution"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1742-9994-2-8","article-title":"Immune response to sympatric and allopatric parasites in a snail-trematode interaction","volume":"2","author":"EE Osnas","year":"2005","journal-title":"Frontiers in Zoology"},{"issue":"5393","key":"ref54","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1126\/science.282.5393.1432","article-title":"Experimental evolution of parasites","volume":"282","author":"D Ebert","year":"1998","journal-title":"Science"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1017\/S0031182000049143","article-title":"Host life-history variation in response to parasitism","volume":"90","author":"DJ Minchella","year":"1985","journal-title":"Parasitology"},{"issue":"5","key":"ref56","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/j.1461-0248.2007.01028.x","article-title":"A synthesis of experimental work on parasite local adaptation","volume":"10","author":"MA Greischar","year":"2007","journal-title":"Ecology letters"},{"issue":"1366","key":"ref57","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1098\/rspb.1996.0019","article-title":"Parasite-host coevolution and geographic patterns of parasite infectivity and host susceptibility","volume":"263","author":"S Morand","year":"1996","journal-title":"Proceedings of the Royal Society B"},{"issue":"2\u20133","key":"ref58","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.micron.2011.09.002","article-title":"Morphological characterization of hemocytes from Biomphalaria glabrata and Biomphalaria straminea","volume":"43","author":"MG Cavalcanti","year":"2012","journal-title":"Micron"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.dci.2017.01.008","article-title":"Small RNA-Seq analysis reveals microRNA-regulation of the Imd pathway during Escherichia coli infection in Drosophila","volume":"70","author":"S Li","year":"2017","journal-title":"Dev Comp Immunol"},{"issue":"3","key":"ref60","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.imbio.2016.11.006","article-title":"MicroRNA profiling of human intermediate monocytes","volume":"222","author":"AM Zawada","year":"2017","journal-title":"Immunobiology"},{"issue":"3","key":"ref61","first-page":"378","article-title":"Schistosomal MicroRNAs Isolated From Extracellular Vesicles in Sera of Infected Patients: A New Tool for Diagnosis and Follow-up of Human Schistosomiasis","volume":"215","author":"T Meningher","year":"2017","journal-title":"Journal of Infectious Diseases"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"28665","DOI":"10.3402\/jev.v4.28665","article-title":"Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni","volume":"4","author":"FC Nowacki","year":"2015","journal-title":"Journal of Extracellular Vesicles"},{"key":"ref63","first-page":"1","article-title":"Trans-kingdom small RNA transfer during host-pathogen interactions: The case of P. falciparum and erythrocytes","author":"KA Walzer","year":"2017","journal-title":"RNA Biology"},{"issue":"16","key":"ref64","doi-asserted-by":"crossref","first-page":"8691","DOI":"10.1073\/pnas.94.16.8691","article-title":"A family of fibrinogen-related proteins that precipitates parasite-derived molecules is produced by an invertebrate after infection","volume":"94","author":"CM Adema","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"14","key":"ref65","doi-asserted-by":"crossref","first-page":"3492","DOI":"10.1016\/j.molimm.2007.03.008","article-title":"Molecular cloning and characterization of a thioester-containing protein from Zhikong scallop Chlamys farreri","volume":"44","author":"H Zhang","year":"2007","journal-title":"Molecular Immunology"},{"issue":"3","key":"ref66","doi-asserted-by":"crossref","first-page":"e1591","DOI":"10.1371\/journal.pntd.0001591","article-title":"A somatically diversified defense factor, FREP3, is a determinant of snail resistance to schistosome infection","volume":"6","author":"PC Hanington","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"10","key":"ref67","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.dci.2005.12.004","article-title":"In vivo and in vitro knockdown of FREP2 gene expression in the snail Biomphalaria glabrata using RNA interference","volume":"30","author":"Y Jiang","year":"2006","journal-title":"Dev Comp Immunol"},{"issue":"3","key":"ref68","doi-asserted-by":"crossref","first-page":"e1003216","DOI":"10.1371\/journal.ppat.1003216","article-title":"Biomphalysin, a new beta pore-forming toxin involved in Biomphalaria glabrata immune defense against Schistosoma mansoni","volume":"9","author":"R Galinier","year":"2013","journal-title":"PLoS pathogens"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.3389\/fimmu.2017.01249","article-title":"Specific Pathogen Recognition by Multiple Innate Immune Sensors in an Invertebrate","volume":"8","author":"G Tetreau","year":"2017","journal-title":"Front Immunol"},{"issue":"6","key":"ref70","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0169-4758(90)90349-9","article-title":"Immune mechanisms in trematod-snail interactions","volume":"6","author":"WPW Van Der Knaap","year":"1990","journal-title":"Parasitology Today"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"20954","DOI":"10.1038\/srep20954","article-title":"Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection","volume":"6","author":"T Crellen","year":"2016","journal-title":"Scientific reports"},{"issue":"Pt 3","key":"ref72","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1017\/S0031182002002792","article-title":"The phylogeny of the Schistosomatidae based on three genes with emphasis on the interrelationships of Schistosoma Weinland, 1858","volume":"126","author":"AE Lockyer","year":"2003","journal-title":"Parasitology"},{"issue":"12","key":"ref73","doi-asserted-by":"crossref","first-page":"3889","DOI":"10.1111\/j.1365-294X.2005.02709.x","article-title":"Origin and diversification of the human parasite Schistosoma mansoni","volume":"14","author":"JA Morgan","year":"2005","journal-title":"Mol Ecol"},{"issue":"1460","key":"ref74","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1098\/rspb.2000.1291","article-title":"Molecular evidence supports an african affinity of the neotropical freshwater gastropod, Biomphalaria glabrata, say 1818, an intermediate host for Schistosoma mansoni","volume":"267","author":"G Campbell","year":"2000","journal-title":"Proceedings of the Royal Society B"},{"issue":"12","key":"ref75","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1093\/oxfordjournals.molbev.a003769","article-title":"Evolutionary relationships and biogeography of Biomphalaria (Gastropoda: Planorbidae) with implications regarding its role as host of the human bloodfluke, Schistosoma mansoni","volume":"18","author":"RJ DeJong","year":"2001","journal-title":"Molecular biology and evolution"},{"key":"ref76","first-page":"205","article-title":"Les schistosomes et leurs h\u00f4tes: apport des marqueurs mol\u00e9culaires \u00e0 la connaissance de leur phylog\u00e9ographie, \u00e9pid\u00e9miologie et \u00e9cologie","volume":"130","author":"A Theron","year":"2005","journal-title":"Bulletin de la Soci\u00e9t\u00e9 Zoologique de France"},{"issue":"123","key":"ref77","doi-asserted-by":"crossref","first-page":"S211","DOI":"10.1017\/S0031182001007703","article-title":"Schistosoma mansoni and Biomphalaria: past history and future trends","author":"JA Morgan","year":"2001","journal-title":"Parasitology"},{"issue":"8","key":"ref78","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S1473-3099(16)00175-4","article-title":"Outbreak of urogenital schistosomiasis in Corsica (France): an epidemiological case study","volume":"16","author":"J Boissier","year":"2016","journal-title":"The Lancet Infectious Diseases"},{"issue":"7","key":"ref79","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S1473-3099(15)00084-5","article-title":"Schistosomiasis reaches Europe","volume":"15","author":"J Boissier","year":"2015","journal-title":"The Lancet Infectious Diseases"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/jmor.1051650104","article-title":"A comparative morphological and enzyme histochemical study on blood cells of the freshwater snails, <italic>Lymnaea stagnalis<\/italic>, <italic>Biomphalaria glabrata<\/italic>, and <italic>Bulinus truncatus<\/italic>","volume":"165","author":"T Sminia","year":"1980","journal-title":"Journal of Morphology"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"22687","DOI":"10.1038\/srep22687","article-title":"High throughput sequencing of small RNAs transcriptomes in two Crassostrea oysters identifies microRNAs involved in osmotic stress response","volume":"6","author":"X Zhao","year":"2016","journal-title":"Scientific reports"},{"issue":"1","key":"ref82","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1186\/gb-2003-5-1-r1","article-title":"MicroRNA targets in Drosophila","volume":"5","author":"AJ Enright","year":"2003","journal-title":"Genome biology"}],"updated-by":[{"DOI":"10.1371\/journal.ppat.1007647","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000}}],"container-title":["PLOS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.ppat.1007647","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T04:13:05Z","timestamp":1588997585000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1007647"}},"subtitle":[],"editor":[{"given":"Matty","family":"Knight","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,3,20]]},"references-count":82,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,3,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1007647","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/378034","asserted-by":"object"}]},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,20]]}}}