{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:08:04Z","timestamp":1787731684435,"version":"build-2784847793"},"reference-count":70,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T00:00:00Z","timestamp":1594771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1008560","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T17:27:54Z","timestamp":1594834074000},"page":"e1008560","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV"],"prefix":"10.1371","volume":"16","author":[{"given":"Sebastian J.","family":"Theobald","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Kreer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahamoddin","family":"Khailaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes","family":"Bonifacius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britta","family":"Eiz-Vesper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constanca","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Mach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8814-4428","authenticated-orcid":true,"given":"Marija","family":"Backovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1352-5995","authenticated-orcid":true,"given":"Matthias","family":"Ballmaier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Koenig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0863-7148","authenticated-orcid":true,"given":"Henning","family":"Olbrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery","family":"Volk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Danisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"Gieselmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meryem Seda","family":"Ercanoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Messerle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5554-1937","authenticated-orcid":true,"given":"Constantin von","family":"Kaisenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten","family":"Witte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Klawonn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Meyer-Hermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Stripecke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,7,15]]},"reference":[{"issue":"3","key":"ppat.1008560.ref001","doi-asserted-by":"crossref","first-page":"e2034","DOI":"10.1002\/rmv.2034","article-title":"Estimation of the worldwide seroprevalence of cytomegalovirus: A systematic review and meta-analysis","volume":"29","author":"M Zuhair","year":"2019","journal-title":"Rev Med Virol"},{"key":"ppat.1008560.ref002","first-page":"7","article-title":"Navigating the Host Cell Response during Entry into Sites of Latent Cytomegalovirus Infection","author":"MJ Murray","year":"2018","journal-title":"Pathogens"},{"issue":"15","key":"ppat.1008560.ref003","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.02392-16","article-title":"Congenital Human Cytomegalovirus Infection and the Enigma of Maternal Immunity","volume":"91","author":"WJ Britt","year":"2017","journal-title":"J Virol"},{"key":"ppat.1008560.ref004","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.3389\/fmicb.2019.01186","article-title":"Human Cytomegalovirus Latency and Reactivation in Allogeneic Hematopoietic Stem Cell Transplant Recipients","volume":"10","author":"L Stern","year":"2019","journal-title":"Front Microbiol"},{"issue":"4","key":"ppat.1008560.ref005","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/cid\/ciu364","article-title":"Donor cytomegalovirus status influences the outcome of allogeneic stem cell transplant: a study by the European group for blood and marrow transplantation","volume":"59","author":"P Ljungman","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"19","key":"ppat.1008560.ref006","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1056\/NEJMoa1309533","article-title":"Letermovir for cytomegalovirus prophylaxis in hematopoietic-cell transplantation","volume":"370","author":"RF Chemaly","year":"2014","journal-title":"N Engl J Med"},{"issue":"25","key":"ppat.1008560.ref007","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1056\/NEJMoa1706640","article-title":"Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation","volume":"377","author":"FM Marty","year":"2017","journal-title":"N Engl J Med"},{"issue":"4","key":"ppat.1008560.ref008","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S1473-3099(11)70024-X","article-title":"Maribavir prophylaxis for prevention of cytomegalovirus disease in recipients of allogeneic stem-cell transplants: a phase 3, double-blind, placebo-controlled, randomised trial","volume":"11","author":"FM Marty","year":"2011","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"ppat.1008560.ref009","article-title":"The Humoral Immune Response Against the gB Vaccine: Lessons Learnt from Protection in Solid Organ Transplantation","volume":"7","author":"AC Gomes","year":"2019","journal-title":"Vaccines (Basel)"},{"issue":"50","key":"ppat.1008560.ref010","doi-asserted-by":"crossref","first-page":"17965","DOI":"10.1073\/pnas.1415310111","article-title":"Antibody-driven design of a human cytomegalovirus gHgLpUL128L subunit vaccine that selectively elicits potent neutralizing antibodies","volume":"111","author":"A Kabanova","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"ppat.1008560.ref011","article-title":"Modeling Human Cytomegalovirus in Humanized Mice for Vaccine Testing","volume":"8","author":"J Koenig","year":"2020","journal-title":"Vaccines (Basel)"},{"issue":"1","key":"ppat.1008560.ref012","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/imm.12906","article-title":"A Hitchhiker's guide to humanized mice: new pathways to studying viral infections","volume":"154","author":"JK Skelton","year":"2018","journal-title":"Immunology"},{"issue":"2","key":"ppat.1008560.ref013","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.AID-0003-2012","article-title":"Humanized Mice for Studying Human Immune Responses and Generating Human Monoclonal Antibodies","volume":"2","author":"R Akkina","year":"2014","journal-title":"Microbiol Spectr"},{"issue":"5","key":"ppat.1008560.ref014","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.4049\/jimmunol.1202810","article-title":"Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation","volume":"190","author":"J Lang","year":"2013","journal-title":"J Immunol"},{"issue":"4","key":"ppat.1008560.ref015","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/iid3.124","article-title":"Improved B cell development in humanized NOD-scid IL2Rgamma(null) mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3","volume":"4","author":"S Jangalwe","year":"2016","journal-title":"Immun Inflamm Dis"},{"key":"ppat.1008560.ref016","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.3389\/fimmu.2018.02734","article-title":"Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34(+) Cells","volume":"9","author":"SJ Theobald","year":"2018","journal-title":"Front Immunol"},{"issue":"1","key":"ppat.1008560.ref017","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/s41598-017-01051-5","article-title":"Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice","volume":"7","author":"LB Crawford","year":"2017","journal-title":"Sci Rep"},{"issue":"10","key":"ppat.1008560.ref018","doi-asserted-by":"crossref","first-page":"4636","DOI":"10.4049\/jimmunol.1302887","article-title":"Dendritic cell-mediated immune humanization of mice: implications for allogeneic and xenogeneic stem cell transplantation","volume":"192","author":"G Salguero","year":"2014","journal-title":"J Immunol"},{"key":"ppat.1008560.ref019","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.3389\/fimmu.2017.01709","article-title":"Multidimensional Analysis Integrating Human T-Cell Signatures in Lymphatic Tissues with Sex of Humanized Mice for Prediction of Responses after Dendritic Cell Immunization","volume":"8","author":"V Volk","year":"2017","journal-title":"Front Immunol"},{"issue":"6","key":"ppat.1008560.ref020","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/j.ajpath.2017.02.015","article-title":"Human Effector Memory T Helper Cells Engage with Mouse Macrophages and Cause Graft-versus-Host-Like Pathology in Skin of Humanized Mice Used in a Nonclinical Immunization Study","volume":"187","author":"B Sundarasetty","year":"2017","journal-title":"Am J Pathol"},{"issue":"10","key":"ppat.1008560.ref021","doi-asserted-by":"crossref","first-page":"e1004377","DOI":"10.1371\/journal.ppat.1004377","article-title":"Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody","volume":"10","author":"N Spindler","year":"2014","journal-title":"PLoS Pathog"},{"issue":"1\u20132","key":"ppat.1008560.ref022","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jim.2007.09.017","article-title":"Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning","volume":"329","author":"T Tiller","year":"2008","journal-title":"J Immunol Methods"},{"key":"ppat.1008560.ref023","first-page":"112752","article-title":"openPrimeR for multiplex amplification of highly diverse templates","volume":"2020","author":"C Kreer","journal-title":"J Immunol Methods"},{"key":"ppat.1008560.ref024","doi-asserted-by":"crossref","first-page":"W34","DOI":"10.1093\/nar\/gkt382","article-title":"IgBLAST: an immunoglobulin variable domain sequence analysis tool","volume":"41","author":"J Ye","year":"2013","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"ppat.1008560.ref025","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1128\/IAI.42.1.237-244.1983","article-title":"Virus-specific antibody activity of different subclasses of immunoglobulins G and A in cytomegalovirus infections","volume":"42","author":"GA Linde","year":"1983","journal-title":"Infect Immun"},{"issue":"10","key":"ppat.1008560.ref026","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1038\/nprot.2016.102","article-title":"Sequencing and cloning of antigen-specific antibodies from mouse memory B cells","volume":"11","author":"L von Boehmer","year":"2016","journal-title":"Nat Protoc"},{"issue":"16","key":"ppat.1008560.ref027","doi-asserted-by":"crossref","first-page":"8927","DOI":"10.1128\/JVI.00434-13","article-title":"Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus","volume":"87","author":"N Spindler","year":"2013","journal-title":"J Virol"},{"issue":"50","key":"ppat.1008560.ref028","doi-asserted-by":"crossref","first-page":"7437","DOI":"10.1016\/j.vaccine.2018.02.089","article-title":"Vaccination against the human cytomegalovirus","volume":"37","author":"SA Plotkin","year":"2019","journal-title":"Vaccine"},{"issue":"24","key":"ppat.1008560.ref029","doi-asserted-by":"crossref","first-page":"6267","DOI":"10.1073\/pnas.1800177115","article-title":"HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions","volume":"115","author":"CS Nelson","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ppat.1008560.ref030","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ebiom.2019.11.005","article-title":"Seronegative patients vaccinated with cytomegalovirus gB-MF59 vaccine have evidence of neutralising antibody responses against gB early post-transplantation","volume":"50","author":"I Baraniak","year":"2019","journal-title":"EBioMedicine"},{"issue":"1","key":"ppat.1008560.ref031","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1182\/blood-2016-07-729756","article-title":"MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults","volume":"129","author":"C La Rosa","year":"2017","journal-title":"Blood"},{"issue":"3","key":"ppat.1008560.ref032","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1128\/JVI.01669-12","article-title":"A vaccine based on the rhesus cytomegalovirus UL128 complex induces broadly neutralizing antibodies in rhesus macaques","volume":"87","author":"F Wussow","year":"2013","journal-title":"J Virol"},{"issue":"19","key":"ppat.1008560.ref033","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01012-18","article-title":"Multiantigenic Modified Vaccinia Virus Ankara Vaccine Vectors To Elicit Potent Humoral and Cellular Immune Reponses against Human Cytomegalovirus in Mice","volume":"92","author":"F Chiuppesi","year":"2018","journal-title":"J Virol"},{"issue":"2","key":"ppat.1008560.ref034","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1089\/vim.2000.13.155","article-title":"Immunogenicity evaluation of DNA vaccines that target guinea pig cytomegalovirus proteins glycoprotein B and UL83","volume":"13","author":"MR Schleiss","year":"2000","journal-title":"Viral Immunol"},{"issue":"4","key":"ppat.1008560.ref035","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S2055-6640(20)30872-4","article-title":"Cytomegalovirus vaccines under clinical development","volume":"2","author":"MR Schleiss","year":"2016","journal-title":"J Virus Erad"},{"issue":"10","key":"ppat.1008560.ref036","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1080\/14760584.2018.1526085","article-title":"A fifty-year odyssey: prospects for a cytomegalovirus vaccine in transplant and congenital infection","volume":"17","author":"DJ Diamond","year":"2018","journal-title":"Expert Review of Vaccines"},{"issue":"12","key":"ppat.1008560.ref037","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1111\/tri.12406","article-title":"Timing of CMV-specific effector memory T cells predicts viral replication and survival after allogeneic hematopoietic stem cell transplantation","volume":"27","author":"I Espigado","year":"2014","journal-title":"Transpl Int"},{"issue":"5","key":"ppat.1008560.ref038","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1084\/jem.20050882","article-title":"Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects","volume":"202","author":"AW Sylwester","year":"2005","journal-title":"J Exp Med"},{"issue":"43","key":"ppat.1008560.ref039","doi-asserted-by":"crossref","first-page":"73654","DOI":"10.18632\/oncotarget.18359","article-title":"Active evolution of memory B-cells specific to viral gH\/gL\/pUL128\/130\/131 pentameric complex in healthy subjects with silent human cytomegalovirus infection","volume":"8","author":"L Xia","year":"2017","journal-title":"Oncotarget"},{"issue":"7","key":"ppat.1008560.ref040","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.bbmt.2009.03.022","article-title":"Increased programmed death-1 molecule expression in cytomegalovirus disease and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation","volume":"15","author":"GM Gallez-Hawkins","year":"2009","journal-title":"Biol Blood Marrow Transplant"},{"issue":"3","key":"ppat.1008560.ref041","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00430-007-0040-7","article-title":"Incidental discovery of high systemic lupus erythematosus disease activity associated with cytomegalovirus viral activity","volume":"196","author":"BY Su","year":"2007","journal-title":"Med Microbiol Immunol"},{"issue":"7","key":"ppat.1008560.ref042","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1007\/s00296-019-04324-6","article-title":"Reactivation of latent cytomegalovirus infection in patients with rheumatologic disease: a case-control study","volume":"39","author":"BJ Gardiner","year":"2019","journal-title":"Rheumatol Int"},{"issue":"1","key":"ppat.1008560.ref043","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s42358-019-0061-0","article-title":"Incidence of Cytomegalovirus Antigenemia in patients with autoimmune rheumatic diseases: a 3-year retrospective study","volume":"59","author":"RP Santos","year":"2019","journal-title":"Adv Rheumatol"},{"issue":"2","key":"ppat.1008560.ref044","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/cmi.2014.75","article-title":"The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies?","volume":"12","author":"MR Wills","year":"2015","journal-title":"Cell Mol Immunol"},{"issue":"10","key":"ppat.1008560.ref045","doi-asserted-by":"crossref","first-page":"e1003635","DOI":"10.1371\/journal.ppat.1003635","article-title":"Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4(+) T cells","volume":"9","author":"GM Mason","year":"2013","journal-title":"PLoS Pathog"},{"key":"ppat.1008560.ref046","article-title":"Adult and cord blood-derived high affinity gB-CAR-T cells effectively react against human cytomegalovirus infections","author":"H Olbrich","year":"2020","journal-title":"Hum Gene Ther"},{"issue":"9","key":"ppat.1008560.ref047","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/gt.2015.43","article-title":"Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma","volume":"22","author":"BS Sundarasetty","year":"2015","journal-title":"Gene Ther"},{"key":"ppat.1008560.ref048","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1186\/s12967-015-0599-5","article-title":"Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation","volume":"13","author":"BS Sundarasetty","year":"2015","journal-title":"J Transl Med"},{"issue":"11","key":"ppat.1008560.ref049","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/nri3311","article-title":"Humanized mice for immune system investigation: progress, promise and challenges","volume":"12","author":"LD Shultz","year":"2012","journal-title":"Nat Rev Immunol"},{"issue":"8","key":"ppat.1008560.ref050","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/s41592-018-0071-6","article-title":"A human immune system mouse model with robust lymph node development","volume":"15","author":"Y Li","year":"2018","journal-title":"Nat Methods"},{"issue":"5","key":"ppat.1008560.ref051","doi-asserted-by":"crossref","first-page":"e19826","DOI":"10.1371\/journal.pone.0019826","article-title":"Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells","volume":"6","author":"R Danner","year":"2011","journal-title":"PLoS One"},{"issue":"2","key":"ppat.1008560.ref052","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1080\/21645515.2017.1403703","article-title":"Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rgammac KO. NOD)","volume":"14","author":"M Mendoza","year":"2018","journal-title":"Hum Vaccin Immunother"},{"issue":"3","key":"ppat.1008560.ref053","doi-asserted-by":"crossref","first-page":"799","DOI":"10.4049\/jimmunol.1801085","article-title":"Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1","volume":"202","author":"MA Gawron","year":"2019","journal-title":"J Immunol"},{"issue":"8","key":"ppat.1008560.ref054","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1182\/blood-2016-04-709584","article-title":"A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production","volume":"129","author":"H Yu","year":"2017","journal-title":"Blood"},{"key":"ppat.1008560.ref055","doi-asserted-by":"crossref","first-page":"520","DOI":"10.3389\/fimmu.2014.00520","article-title":"IgG subclasses and allotypes: from structure to effector functions","volume":"5","author":"G Vidarsson","year":"2014","journal-title":"Front Immunol"},{"key":"ppat.1008560.ref056","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jcv.2017.03.005","article-title":"Comparison of cytomegalovirus (CMV)-specific neutralization capacity of hyperimmunoglobulin (HIG) versus standard intravenous immunoglobulin (IVIG) preparations: Impact of CMV IgG normalization","volume":"90","author":"MS Schampera","year":"2017","journal-title":"J Clin Virol"},{"issue":"8","key":"ppat.1008560.ref057","doi-asserted-by":"crossref","first-page":"e1006601","DOI":"10.1371\/journal.ppat.1006601","article-title":"Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus","volume":"13","author":"A Bootz","year":"2017","journal-title":"PLoS Pathog"},{"issue":"6424","key":"ppat.1008560.ref058","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1126\/science.aat0066","article-title":"Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation","volume":"363","author":"JP Martins","year":"2019","journal-title":"Science"},{"issue":"9","key":"ppat.1008560.ref059","article-title":"Large-Scale Screening of HCMV-Seropositive Blood Donors Indicates that HCMV Effectively Escapes from Antibodies by Cell-Associated Spread","volume":"10","author":"JJ Falk","year":"2018","journal-title":"Viruses"},{"issue":"23","key":"ppat.1008560.ref060","doi-asserted-by":"crossref","first-page":"6104","DOI":"10.1073\/pnas.1704809114","article-title":"The pentameric complex drives immunologically covert cell-cell transmission of wild-type human cytomegalovirus","volume":"114","author":"I Murrell","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"ppat.1008560.ref061","article-title":"Neutralization of Human Cytomegalovirus Entry into Fibroblasts and Epithelial Cells","volume":"5","author":"F Wussow","year":"2017","journal-title":"Vaccines (Basel)"},{"key":"ppat.1008560.ref062","doi-asserted-by":"crossref","first-page":"14060","DOI":"10.1038\/mtm.2014.60","article-title":"Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV","volume":"1","author":"A Daenthanasanmak","year":"2015","journal-title":"Mol Ther Methods Clin Dev"},{"key":"ppat.1008560.ref063","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jviromet.2016.06.008","article-title":"Generation of a Gaussia luciferase-expressing endotheliotropic cytomegalovirus for screening approaches and mutant analyses","volume":"235","author":"JJ Falk","year":"2016","journal-title":"J Virol Methods"},{"issue":"19","key":"ppat.1008560.ref064","doi-asserted-by":"crossref","first-page":"10489","DOI":"10.1128\/JVI.01546-13","article-title":"Impact of sequence variation in the UL128 locus on production of human cytomegalovirus in fibroblast and epithelial cells","volume":"87","author":"I Murrell","year":"2013","journal-title":"J Virol"},{"issue":"4","key":"ppat.1008560.ref065","doi-asserted-by":"crossref","first-page":"469","DOI":"10.2144\/000112123","article-title":"Amplification and analysis of cDNA generated from a single cell by 5'-RACE: application to isolation of antibody heavy and light chain variable gene sequences from single B cells","volume":"40","author":"T Ozawa","year":"2006","journal-title":"Biotechniques"},{"issue":"1\u20132","key":"ppat.1008560.ref066","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jim.2009.08.009","article-title":"Cloning and expression of murine Ig genes from single B cells","volume":"350","author":"T Tiller","year":"2009","journal-title":"J Immunol Methods"},{"issue":"10","key":"ppat.1008560.ref067","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1038\/s41591-019-0602-4","article-title":"Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV","volume":"25","author":"SA Ehrhardt","year":"2019","journal-title":"Nat Med"},{"issue":"4","key":"ppat.1008560.ref068","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1109\/91.940964","article-title":"Effect of Rule Weights in Fuzzy Rule-Based Classiffication Systems","volume":"9","author":"H Ishibuchi","year":"2001","journal-title":"IEEE Transactions on Fuzzy Systems"},{"issue":"6","key":"ppat.1008560.ref069","first-page":"1","article-title":"Frbs: fuzzy rule-based Systems for Classification and Regression in R","volume":"65","author":"LS Riza","year":"2015","journal-title":"J Stat Softw"},{"key":"ppat.1008560.ref070","volume-title":"R: A Language and Environment for Statistical Computing.","author":"R Development Core Team"}],"updated-by":[{"DOI":"10.1371\/journal.ppat.1009385","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000}}],"container-title":["PLOS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1008560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T21:52:14Z","timestamp":1667425934000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1008560"}},"subtitle":[],"editor":[{"given":"Christopher M.","family":"Snyder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,7,15]]},"references-count":70,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,7,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1008560","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.ppat.1009385","asserted-by":"object"}]},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,15]]}}}