{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:11:42Z","timestamp":1790115102733,"version":"4.0.1"},"update-to":[{"DOI":"10.1371\/journal.ppat.1010548","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000}}],"reference-count":49,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T00:00:00Z","timestamp":1652400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key Research and Development Plan of China","award":["2021YFD1400500"],"award-info":[{"award-number":["2021YFD1400500"]}]},{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32022072"],"award-info":[{"award-number":["32022072"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32172416"],"award-info":[{"award-number":["32172416"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32100103"],"award-info":[{"award-number":["32100103"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LZ22C140001"],"award-info":[{"award-number":["LZ22C140001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004387","name":"Ningbo University","doi-asserted-by":"crossref","award":["K. C. Wong Magna Fund"],"award-info":[{"award-number":["K. C. Wong Magna Fund"]}],"id":[{"id":"10.13039\/501100004387","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"abstract":"<jats:p>\n                    NF-Y transcription factors are known to play many diverse roles in the development and physiological responses of plants but little is known about their role in plant defense. Here, we demonstrate the negative roles of rice\n                    <jats:italic>NF-YA<\/jats:italic>\n                    family genes in antiviral defense against two different plant viruses,\n                    <jats:italic>Rice stripe virus<\/jats:italic>\n                    (RSV,\n                    <jats:italic>Tenuivirus<\/jats:italic>\n                    ) and\n                    <jats:italic>Southern rice black-streaked dwarf virus<\/jats:italic>\n                    (SRBSDV,\n                    <jats:italic>Fijivirus<\/jats:italic>\n                    ). RSV and SRBSDV both induced the expression of\n                    <jats:italic>OsNF-YA<\/jats:italic>\n                    family genes. Overexpression of\n                    <jats:italic>OsNF-YAs<\/jats:italic>\n                    enhanced rice susceptibility to virus infection, while\n                    <jats:italic>OsNF-YAs<\/jats:italic>\n                    RNAi mutants were more resistant. Transcriptome sequencing showed that the expression of jasmonic acid (JA)-related genes was significantly decreased in plants overexpressing\n                    <jats:italic>OsNF-YA<\/jats:italic>\n                    when they were infected by viruses. qRT-PCR and JA sensitivity assays confirmed that OsNF-YAs play negative roles in regulating the JA pathway. Further experiments showed that OsNF-YAs physically interact with JA signaling transcription factors OsMYC2\/3 and interfere with JA signaling by dissociating the OsMYC2\/3-OsMED25 complex, which inhibits the transcriptional activation activity of OsMYC2\/3. Together, our results reveal that OsNF-YAs broadly inhibit plant antiviral defense by repressing JA signaling pathways, and provide new insight into how OsNF-YAs are directly associated with the JA pathway.\n                  <\/jats:p>","DOI":"10.1371\/journal.ppat.1010548","type":"journal-article","created":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T13:41:46Z","timestamp":1652449306000},"page":"e1010548","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":63,"title":["NF-YA transcription factors suppress jasmonic acid-mediated antiviral defense and facilitate viral infection in rice"],"prefix":"10.1371","volume":"18","author":[{"given":"Xiaoxiang","family":"Tan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hehong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongyan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3300-8984","authenticated-orcid":true,"given":"Zongtao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,5,13]]},"reference":[{"issue":"1","key":"ppat.1010548.ref001","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev-phyto-080615-095900","article-title":"Rice 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Yao","year":"2019","journal-title":"Mol Plant"},{"issue":"1","key":"ppat.1010548.ref005","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1038\/ncomms5768","article-title":"STV11 encodes a sulphotransferase and confers durable resistance to rice stripe virus.","volume":"5","author":"Q Wang","year":"2014","journal-title":"Nat Commun"},{"key":"ppat.1010548.ref006","doi-asserted-by":"crossref","first-page":"e27529","DOI":"10.7554\/eLife.27529","article-title":"A viral protein promotes host SAMS1 activity and ethylene production for the benefit of virus infection.","volume":"6","author":"S Zhao","year":"2017","journal-title":"eLife"},{"issue":"12","key":"ppat.1010548.ref007","doi-asserted-by":"crossref","first-page":"e1009118","DOI":"10.1371\/journal.ppat.1009118","article-title":"Auxin response factors (ARFs) differentially regulate rice antiviral immune response against rice dwarf virus.","volume":"16","author":"Q Qin","year":"2020","journal-title":"PLoS 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