{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:52:43Z","timestamp":1792788763208,"version":"4.5.0"},"reference-count":167,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T00:00:00Z","timestamp":1657152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003977","name":"Israel Science Foundation","doi-asserted-by":"publisher","award":["1523\/18"],"award-info":[{"award-number":["1523\/18"]}],"id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001738","name":"Ministry of Science, Technology and Space","doi-asserted-by":"publisher","award":["3-16285 and 103240"],"award-info":[{"award-number":["3-16285 and 103240"]}],"id":[{"id":"10.13039\/501100001738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006221","name":"United States - Israel Binational Science Foundation","doi-asserted-by":"publisher","award":["2019236"],"award-info":[{"award-number":["2019236"]}],"id":[{"id":"10.13039\/100006221","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Dr. Louis M. Leland and Ruth M. Leland Chair in Infectious Diseases"}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"abstract":"<jats:p>\n                    In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important regulators of multifaceted biological processes, including transcriptional, posttranscriptional, and epigenetic regulation of gene expression. In recent years, it is becoming clear that protozoan parasites encode diverse ncRNA transcripts; however, little is known about their cellular functions. Recent advances in high-throughput \u201comic\u201d studies identified many novel long ncRNAs (lncRNAs) in apicomplexan parasites, some of which undergo splicing, polyadenylation, and encode small proteins. To date, only a few of them are characterized, leaving a big gap in our understanding regarding their origin, mode of action, and functions in parasite biology. In this review, we focus on lncRNAs of the human malaria parasite\n                    <jats:italic>Plasmodium falciparum<\/jats:italic>\n                    and highlight their cellular functions and possible mechanisms of action.\n                  <\/jats:p>","DOI":"10.1371\/journal.ppat.1010600","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T13:23:31Z","timestamp":1657200211000},"page":"e1010600","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":28,"title":["Emerging biology of noncoding RNAs in malaria parasites"],"prefix":"10.1371","volume":"18","author":[{"given":"Karina","family":"Simantov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7878-1650","authenticated-orcid":true,"given":"Ron","family":"Dzikowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,7,7]]},"reference":[{"key":"ppat.1010600.ref001","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.7924.1","article-title":"Recent advances in understanding apicomplexan parasites","volume":"5","author":"F Seeber","year":"2016","journal-title":"F1000Res"},{"key":"ppat.1010600.ref002","year":"2020","journal-title":"WHO. 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