{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:22:51Z","timestamp":1789474971072,"version":"build-2803163510"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T00:00:00Z","timestamp":1696464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000268","name":"BBSRC","doi-asserted-by":"crossref","award":["BB\/W009625\/1"],"award-info":[{"award-number":["BB\/W009625\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100019690","name":"Medical Research Council Centre for Medical Mycology","doi-asserted-by":"publisher","award":["MR\/N006364\/2"],"award-info":[{"award-number":["MR\/N006364\/2"]}],"id":[{"id":"10.13039\/501100019690","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019690","name":"Medical Research Council Centre for Medical Mycology","doi-asserted-by":"publisher","award":["MR\/N006364\/2"],"award-info":[{"award-number":["MR\/N006364\/2"]}],"id":[{"id":"10.13039\/501100019690","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019690","name":"Medical Research Council Centre for Medical Mycology","doi-asserted-by":"publisher","award":["MR\/V033417\/1"],"award-info":[{"award-number":["MR\/V033417\/1"]}],"id":[{"id":"10.13039\/501100019690","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019690","name":"Medical Research Council Centre for Medical Mycology","doi-asserted-by":"publisher","award":["MR\/V033417\/1"],"award-info":[{"award-number":["MR\/V033417\/1"]}],"id":[{"id":"10.13039\/501100019690","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"DOI":"10.1371\/journal.ppat.1011651","type":"journal-article","created":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T17:22:25Z","timestamp":1696526545000},"page":"e1011651","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":38,"title":["Candida glabrata: A powerhouse of resistance"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6177-577X","authenticated-orcid":true,"given":"Se\u00e1na","family":"Duggan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0604-291X","authenticated-orcid":true,"given":"Jane","family":"Usher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"issue":"1","key":"ppat.1011651.ref001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2010.02102.x","article-title":"From Saccharomyces cerevisiae to Candida glabrata in a few easy steps: Important adaptations for an opportunistic pathogen","volume":"314","author":"A Roetzer","year":"2011","journal-title":"FEMS Microbiol Lett"},{"issue":"1","key":"ppat.1011651.ref002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s42003-021-02412-7","article-title":"From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view","volume":"4","author":"M Cavalheiro","year":"2021","journal-title":"Commun Biol"},{"issue":"3","key":"ppat.1011651.ref003","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.fgb.2008.11.006","article-title":"Genomic polymorphism in the population of Candida glabrata: Gene copy-number variation and chromosomal translocations","volume":"46","author":"H Muller","year":"2009","journal-title":"Fungal Genet Biol"},{"issue":"8","key":"ppat.1011651.ref004","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1073\/pnas.0809793106","article-title":"Formation of new chromosomes as a virulence mechanism in yeast candida glabrata","volume":"106","author":"S Pol\u00e1kov\u00e1","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"ppat.1011651.ref005","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1093\/molbev\/msz104","article-title":"Aneuploidy Enables Cross-Adaptation to Unrelated Drugs","volume":"36","author":"F Yang","year":"2019","journal-title":"Mol Biol Evol"},{"issue":"5","key":"ppat.1011651.ref006","first-page":"2892","article-title":"Candida albicans and Candida glabrata clinical isolates exhibiting reduced echinocandin susceptibility","volume":"8","author":"EM Torres","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"issue":"11","key":"ppat.1011651.ref007","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1128\/EC.00284-08","article-title":"The cell wall of the human pathogen Candida glabrata: Differential incorporation of novel adhesin-like wall proteins","volume":"7","author":"PWJ De Groot","year":"2008","journal-title":"Eukaryot Cell"},{"issue":"April","key":"ppat.1011651.ref008","first-page":"248","article-title":"Architecture of the dynamic fungal cell wall","volume":"21","author":"NAR Gow","year":"2022","journal-title":"Nat Rev Microbiol"},{"key":"ppat.1011651.ref009","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2019.02993","article-title":"The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species","volume":"10","author":"R Garcia-Rubio","year":"2020","journal-title":"Front Microbiol"},{"issue":"1","key":"ppat.1011651.ref010","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/mmi.14707","article-title":"Cell wall protein variation, break-induced replication, and subtelomere dynamics in Candida glabrata","volume":"116","author":"Z Xu","year":"2021","journal-title":"Mol Microbiol"},{"issue":"8","key":"ppat.1011651.ref011","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/yea.1792","article-title":"The high-osmolarity glycerol (HOG) and cell wall integrity (CWI) signalling pathways interplay: A yeast dialogue between MAPK routes","volume":"27","author":"JM Rodr\u00edguez-Pena","year":"2010","journal-title":"Yeast"},{"issue":"18","key":"ppat.1011651.ref012","doi-asserted-by":"crossref","first-page":"7628","DOI":"10.1073\/pnas.0611195104","article-title":"A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata","volume":"104","author":"R Kaur","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"ppat.1011651.ref013","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1534\/g3.117.042887","article-title":"Comparative genomics of two sequential Candida glabrata clinical isolates","volume":"7","author":"L Vale-Silva","year":"2017","journal-title":"G3: Genes, Genomes. Genetics"},{"issue":"6","key":"ppat.1011651.ref014","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s11046-011-9446-2","article-title":"Identification and Differential Gene Expression of Adhesin-Like Wall Proteins in Candida glabrata Biofilms","volume":"172","author":"EA Kraneveld","year":"2011","journal-title":"Mycopathologia"},{"key":"ppat.1011651.ref015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2015.00919","article-title":"Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate","volume":"6","author":"S Mota","year":"2015","journal-title":"Front Microbiol"},{"issue":"4\u20135","key":"ppat.1011651.ref016","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10142-002-0058-2","article-title":"The genomics of yeast responses to environmental stress and starvation","volume":"2","author":"AP Gasch","year":"2002","journal-title":"Funct Integr Genomics"},{"issue":"8","key":"ppat.1011651.ref017","doi-asserted-by":"crossref","DOI":"10.3390\/jof7080667","article-title":"Candida glabrata: Pathogenicity and resistance mechanisms for adaptation and survival","volume":"7","author":"Y Hassan","year":"2021","journal-title":"J Fungi"},{"issue":"8","key":"ppat.1011651.ref018","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1080\/21505594.2017.1347744","article-title":"Galleria mellonella as a host model to study Candida glabrata virulence and antifungal efficacy","volume":"8","author":"L Ames","year":"2017","journal-title":"Virulence"},{"issue":"13","key":"ppat.1011651.ref019","first-page":"1","article-title":"Physiologically relevant alternative carbon sources modulate biofilm formation, cell wall architecture, and the stress and antifungal resistance of candida glabrata","volume":"20","author":"SY Chew","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"9","key":"ppat.1011651.ref020","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1111\/cmi.12443","article-title":"Neutrophil activation by Candida glabrata but not Candida albicans promotes fungal uptake by monocytes","volume":"17","author":"S Duggan","year":"2015","journal-title":"Cell Microbiol"},{"issue":"3","key":"ppat.1011651.ref021","doi-asserted-by":"crossref","first-page":"e17589","DOI":"10.1371\/journal.pone.0017589","article-title":"Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata","volume":"6","author":"S Ferrari","year":"2011","journal-title":"PLoS ONE"},{"issue":"4","key":"ppat.1011651.ref022","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/jof6040321","article-title":"Amphotericin b and other polyenes\u2014discovery, clinical use, mode of action and drug resistance","volume":"6","author":"H Carolus","year":"2020","journal-title":"J Fungi"},{"issue":"2","key":"ppat.1011651.ref023","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1080\/21505594.2016.1196300","article-title":"Combinatorial strategies for combating invasive fungal infections","volume":"8","author":"M Spitzer","year":"2017","journal-title":"Virulence"},{"issue":"5","key":"ppat.1011651.ref024","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1128\/IAI.00074-13","article-title":"Gain-of-function mutations in PDR1, a regulator of antifungal drug resistance in candida glabrata, control adherence to host cells","volume":"81","author":"L Vale-Silva","year":"2013","journal-title":"Infect Immun"},{"issue":"3","key":"ppat.1011651.ref025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jacamr\/dlab122","article-title":"Emergence of resistant Candida glabrata in Germany","volume":"3","author":"AM Aldejohann","year":"2021","journal-title":"JAC Antimicrob Resist"},{"issue":"10","key":"ppat.1011651.ref026","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1001692","article-title":"Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B","volume":"11","author":"BM Vincent","year":"2013","journal-title":"PLoS Biol"}],"container-title":["PLOS Pathogens"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1011651","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T11:49:01Z","timestamp":1703332141000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.ppat.1011651"}},"subtitle":[],"editor":[{"given":"Mary Ann","family":"Jabra-Rizk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,10,5]]},"references-count":26,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.ppat.1011651","relation":{},"ISSN":["1553-7374"],"issn-type":[{"value":"1553-7374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,5]]}}}