{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T23:46:27Z","timestamp":1791935187574,"version":"4.3.4"},"reference-count":242,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:00:00Z","timestamp":1743379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["RO1AI170692"],"award-info":[{"award-number":["RO1AI170692"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI158615"],"award-info":[{"award-number":["R01AI158615"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015283","name":"Bloomberg Philanthropies","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/100015283","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"abstract":"<jats:p>\n                    Malaria is a life-threatening mosquito-borne disease caused by the\n                    <jats:italic>Plasmodium<\/jats:italic>\n                    parasite, responsible for more than half a million deaths annually and principally involving children. The successful transmission of malaria by\n                    <jats:italic>Anopheles<\/jats:italic>\n                    mosquitoes relies on complex successive interactions between the parasite and various mosquito organs, host factors, and restriction factors. This review summarizes our current understanding of the mechanisms regulating\n                    <jats:italic>Plasmodium<\/jats:italic>\n                    infection of the mosquito vector at successive plasmodial developmental stages and highlights potential transmission-blocking targets and strategies.\n                  <\/jats:p>","DOI":"10.1371\/journal.ppat.1012965","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T15:33:41Z","timestamp":1743435221000},"page":"e1012965","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":17,"title":["Advances in the dissection of Anopheles\u2013Plasmodium interactions"],"prefix":"10.1371","volume":"21","author":[{"given":"Sally A.","family":"Saab","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Cardoso-Jaime","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Kefi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6755-8111","authenticated-orcid":true,"given":"George","family":"Dimopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,3,31]]},"reference":[{"issue":"1","key":"ppat.1012965.ref001","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1128\/MMBR.64.1.115-137.2000","article-title":"Genetics of mosquito vector competence","volume":"64","author":"BT Beerntsen","year":"2000","journal-title":"Microbiol Mol Biol Rev"},{"key":"ppat.1012965.ref002","volume-title":"World Health 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