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This resilience has been attributed mainly to bacterial defenses, yet we show that host plasma proteins act as transient allies, consistent with a role in mitigating oxidative stress immediately after the blood meal. These findings reframe blood not only as nutrition but also as an active modulator of vector competence.\n                  <\/jats:p>","DOI":"10.1371\/journal.ppat.1014022","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T18:39:30Z","timestamp":1772217570000},"page":"e1014022","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Plasma albumin contributes to early Yersinia pestis survival at the onset of flea infection"],"prefix":"10.1371","volume":"22","author":[{"given":"Am\u00e9lie","family":"Dewitte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Sebbane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1834-5416","authenticated-orcid":true,"given":"S\u00e9bastien","family":"Bontemps-Gallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"ppat.1014022.ref001","first-page":"423","article-title":"LXVII. 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