{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:13:09Z","timestamp":1790014389107,"version":"4.0.1"},"reference-count":78,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-16- CONV-0005"],"award-info":[{"award-number":["ANR-16- CONV-0005"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-10-LABX-62-IBEID"],"award-info":[{"award-number":["ANR-10-LABX-62-IBEID"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Institut Pasteur","award":["PTR 1824-24"],"award-info":[{"award-number":["PTR 1824-24"]}],"id":[{"id":"https:\/\/ror.org\/0495fxg12","id-type":"ROR","asserted-by":"crossref"}]},{"name":"HORIZON-HLTH-2021","award":["DISEASE-04-DI-DIDA project"],"award-info":[{"award-number":["DISEASE-04-DI-DIDA project"]}]},{"name":"HORIZON-HLTH-2021","award":["DISEASE-04-DI-DIDA project"],"award-info":[{"award-number":["DISEASE-04-DI-DIDA project"]}]}],"content-domain":{"domain":["www.plospathogens.org"],"crossmark-restriction":false},"short-container-title":["PLoS Pathog"],"abstract":"<jats:p>\n                    Phagocytosis is a cornerstone of the immune defence, allowing cells to eliminate pathogens through both opsonic and non-opsonic pathways. In protozoa such as\n                    <jats:italic>Entamoeba histolytica<\/jats:italic>\n                    , non-opsonic phagocytosis is not only central to survival but also to its ability to cause disease, with its life cycle closely intertwined with the intestinal microbiota, which supplies bacteria and their metabolic byproducts to support trophozoite growth. Yet, despite its significance, the molecular basis of how\n                    <jats:italic>E. histolytica<\/jats:italic>\n                    recognises and engulfs bacteria remains largely unresolved. This review examines the cell-surface molecules that may mediate bacteria\u2013amoeba interactions and highlights new strategies to uncover their roles, offering fresh insight into the dynamics of non-opsonic phagocytosis.\n                  <\/jats:p>","DOI":"10.1371\/journal.ppat.1014560","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:51:00Z","timestamp":1790013060000},"page":"e1014560","update-policy":"https:\/\/doi.org\/10.1371\/journal.ppat.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring glycocalyx components powering the contact between Entamoeba histolytica and bacteria during non-opsonic phagocytosis"],"prefix":"10.1371","volume":"22","author":[{"given":"Elisabeth","family":"Labruy\u00e8re","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Biological Image Analysis Unit, Centre National de la Recherche Scientifique UMR3691","place":["Paris, France"],"department":["Institut Pasteur"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Treport","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Biological Image Analysis Unit, Centre National de la Recherche Scientifique UMR3691","place":["Paris, France"],"department":["Institut Pasteur"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Christophe","family":"Olivo-Marin","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Biological Image Analysis Unit, Centre National de la Recherche Scientifique UMR3691","place":["Paris, France"],"department":["Institut Pasteur"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6551-9012","authenticated-orcid":true,"given":"Nancy","family":"Guillen","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Biological Image Analysis Unit, Centre National de la Recherche Scientifique UMR3691","place":["Paris, France"],"department":["Institut Pasteur"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"ppat.1014560.ref001","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1146\/annurev.immunol.20.103001.114744","article-title":"Phagocytosis of microbes: complexity in action","volume":"20","author":"DM Underhill","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"ppat.1014560.ref002","doi-asserted-by":"crossref","first-page":"662063","DOI":"10.3389\/fimmu.2021.662063","article-title":"Microbial Phagocytic receptors and their potential involvement in cytokine induction in macrophages","volume":"12","author":"YL Fu","year":"2021","journal-title":"Front Immunol"},{"issue":"2","key":"ppat.1014560.ref003","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ydbio.2012.11.006","article-title":"Phagocyte dynamics in a highly regenerative 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