{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T07:53:29Z","timestamp":1773474809554,"version":"3.50.1"},"reference-count":77,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2014,5,15]],"date-time":"2014-05-15T00:00:00Z","timestamp":1400112000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosgenetics.org"],"crossmark-restriction":false},"short-container-title":["PLoS Genet"],"DOI":"10.1371\/journal.pgen.1004375","type":"journal-article","created":{"date-parts":[[2014,5,15]],"date-time":"2014-05-15T20:37:27Z","timestamp":1400186247000},"page":"e1004375","update-policy":"https:\/\/doi.org\/10.1371\/journal.pgen.corrections_policy","source":"Crossref","is-referenced-by-count":109,"title":["Intron Retention in the 5\u2032UTR of the Novel ZIF2 Transporter Enhances Translation to Promote Zinc Tolerance in Arabidopsis"],"prefix":"10.1371","volume":"10","author":[{"given":"Estelle","family":"Remy","sequence":"first","affiliation":[]},{"given":"T\u00e2nia R.","family":"Cabrito","sequence":"additional","affiliation":[]},{"given":"Rita A.","family":"Batista","sequence":"additional","affiliation":[]},{"given":"Mohamed A. M.","family":"Hussein","sequence":"additional","affiliation":[]},{"given":"Miguel C.","family":"Teixeira","sequence":"additional","affiliation":[]},{"given":"Alekos","family":"Athanasiadis","sequence":"additional","affiliation":[]},{"given":"Isabel","family":"S\u00e1-Correia","sequence":"additional","affiliation":[]},{"given":"Paula","family":"Duque","sequence":"additional","affiliation":[]}],"member":"340","published-online":{"date-parts":[[2014,5,15]]},"reference":[{"key":"ref1","unstructured":"Marschner H (1995) Mineral Nutrition of Higher Plants. London: Academic Press."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s004250000458","article-title":"Molecular mechanisms of plant metal tolerance and homeostasis","volume":"212","author":"S Clemens","year":"2001","journal-title":"Planta"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/j.bbamcr.2012.05.016","article-title":"The zinc homeostasis network of land plants","volume":"1823","author":"SA Sinclair","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.4161\/psb.5.12.13469","article-title":"Regulation of the adaptation to zinc deficiency in plants","volume":"5","author":"AG Assun\u00e7\u00e3o","year":"2010","journal-title":"Plant Signal Behav"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"3712","DOI":"10.1104\/pp.104.046292","article-title":"Arabidopsis HMA2, a divalent heavy metal-transporting P(IB)-type ATPase, is involved in cytoplasmic Zn2+ homeostasis","volume":"136","author":"E Eren","year":"2004","journal-title":"Plant Physiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1104\/pp.108.127472","article-title":"Phytochelatin synthesis is essential for the detoxification of excess zinc and contributes significantly to the accumulation of zinc","volume":"149","author":"P Tennstedt","year":"2009","journal-title":"Plant Physiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1105\/tpc.111.095042","article-title":"Vacuolar nicotianamine has critical and distinct roles under iron deficiency and for zinc sequestration in Arabidopsis","volume":"24","author":"MJ Haydon","year":"2012","journal-title":"Plant Cell"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1093\/pcp\/pci015","article-title":"Zinc transporter of Arabidopsis thaliana AtMTP1 is localized to vacuolar membranes and implicated in zinc homeostasis","volume":"45","author":"Y Kobae","year":"2004","journal-title":"Plant Cell Physiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"4165","DOI":"10.1016\/j.febslet.2005.06.046","article-title":"Arabidopsis thaliana MTP1 is a Zn transporter in the vacuolar membrane which mediates Zn detoxification and drives leaf Zn accumulation","volume":"579","author":"AG Desbrosses-Fonrouge","year":"2005","journal-title":"FEBS Lett"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/j.1365-313X.2006.02746.x","article-title":"The Arabidopsis metal tolerance protein AtMTP3 maintains metal homeostasis by mediating Zn exclusion from the shoot under Fe deficiency and Zn oversupply","volume":"46","author":"S Arrivault","year":"2006","journal-title":"Plant J"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1105\/tpc.109.070185","article-title":"Arabidopsis PCR2 is a zinc exporter involved in both zinc extrusion and long-distance zinc transport","volume":"22","author":"WY Song","year":"2010","journal-title":"Plant Cell"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"47644","DOI":"10.1074\/jbc.M309338200","article-title":"Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis","volume":"278","author":"H Wintz","year":"2003","journal-title":"J Biol Chem"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/jxb\/ers315","article-title":"Transport properties of members of the ZIP family in plants and their role in Zn and Mn homeostasis","volume":"64","author":"MJ Milner","year":"2013","journal-title":"J Exp Bot"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"e37193","DOI":"10.1371\/journal.pone.0037193","article-title":"Modeling regulation of zinc uptake via ZIP transporters in yeast and plant roots","volume":"7","author":"J Claus","year":"2012","journal-title":"PLoS One"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.febslet.2004.09.023","article-title":"Overexpression of AtHMA4 enhances root-to-shoot translocation of zinc and cadmium and plant metal tolerance","volume":"576","author":"F Verret","year":"2004","journal-title":"FEBS Lett"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.febslet.2004.12.040","article-title":"The plant P1B-type ATPase AtHMA4 transports Zn and Cd and plays a role in detoxification of transition metals supplied at elevated levels","volume":"579","author":"RF Mills","year":"2005","journal-title":"FEBS Lett"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1105\/tpc.020487","article-title":"P-type ATPase heavy metal transporters with roles in essential zinc homeostasis in Arabidopsis","volume":"16","author":"D Hussain","year":"2004","journal-title":"Plant Cell"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/j.1365-313X.2009.03818.x","article-title":"AtHMA1 contributes to the detoxification of excess Zn(II) in Arabidopsis","volume":"58","author":"YY Kim","year":"2009","journal-title":"Plant J"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1104\/pp.108.130294","article-title":"AtHMA3, a P1B-ATPase allowing Cd\/Zn\/Co\/Pb vacuolar storage in Arabidopsis","volume":"149","author":"M Morel","year":"2009","journal-title":"Plant Physiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1104\/pp.106.092015","article-title":"A novel major facilitator superfamily protein at the tonoplast influences zinc tolerance and accumulation in Arabidopsis","volume":"143","author":"MJ Haydon","year":"2007","journal-title":"Plant Physiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1104\/pp.112.4.1715","article-title":"Physiological Characterization of Root Zn2+ Absorption and Translocation to Shoots in Zn Hyperaccumulator and Nonaccumulator Species of Thlaspi","volume":"112","author":"MM Lasat","year":"1996","journal-title":"Plant Physiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1104\/pp.105.076232","article-title":"Zinc-dependent global transcriptional control, transcriptional deregulation, and higher gene copy number for genes in metal homeostasis of the hyperaccumulator Arabidopsis halleri","volume":"142","author":"IN Talke","year":"2006","journal-title":"Plant Physiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1046\/j.1365-313X.2003.01959.x","article-title":"Cross-species microarray transcript profiling reveals high constitutive expression of metal homeostasis genes in shoots of the zinc hyperaccumulator Arabidopsis halleri","volume":"37","author":"M Becher","year":"2004","journal-title":"Plant J"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1046\/j.1365-313X.2003.01960.x","article-title":"Comparative microarray analysis of Arabidopsis thaliana and Arabidopsis halleri roots identifies nicotianamine synthase, a ZIP transporter and other genes as potential metal hyperaccumulation factors","volume":"37","author":"M Weber","year":"2004","journal-title":"Plant J"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.62.1.1-34.1998","article-title":"Major facilitator superfamily","volume":"62","author":"SS Pao","year":"1998","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1146\/annurev.arplant.57.032905.105406","article-title":"Plant ATP-binding cassette transporters","volume":"58","author":"PA Rea","year":"2007","journal-title":"Annu Rev Plant Biol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1101\/gr.134106.111","article-title":"Transcriptome survey reveals increased complexity of the alternative splicing landscape in Arabidopsis","volume":"22","author":"Y Marquez","year":"2012","journal-title":"Genome Res"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1007\/s00709-012-0448-9","article-title":"On the physiological significance of alternative splicing events in higher plants","volume":"250","author":"RF Carvalho","year":"2013","journal-title":"Protoplasma"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1105\/tpc.113.110353","article-title":"A major facilitator superfamily transporter plays a dual role in polar auxin transport and drought stress tolerance in Arabidopsis","volume":"25","author":"E Remy","year":"2013","journal-title":"Plant Cell"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1111\/j.1365-313X.2007.03212.x","article-title":"A multicolored set of in vivo organelle markers for co-localization studies in Arabidopsis and other plants","volume":"51","author":"BK Nelson","year":"2007","journal-title":"Plant J"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1093\/emboj\/19.12.2845","article-title":"Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae","volume":"19","author":"CW MacDiarmid","year":"2000","journal-title":"EMBO J"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"23203","DOI":"10.1074\/jbc.271.38.23203","article-title":"The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae","volume":"271","author":"H Zhao","year":"1996","journal-title":"J Biol Chem"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S1389-1723(03)80196-2","article-title":"Mutational analysis and localization of the inositol transporters of Saccharomyces cerevisiae","volume":"96","author":"M Miyashita","year":"2003","journal-title":"J Biosci Bioeng"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1365-313X.2004.02161.x","article-title":"Phosphate transport in Arabidopsis: Pht1;1 and Pht1;4 play a major role in phosphate acquisition from both low- and high-phosphate environments","volume":"39","author":"H Shin","year":"2004","journal-title":"Plant J"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1038\/nprot.2007.199","article-title":"Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis","volume":"2","author":"SD Yoo","year":"2007","journal-title":"Nat Protoc"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1038\/nature06069","article-title":"A central integrator of transcription networks in plant stress and energy signalling","volume":"448","author":"E Baena-Gonzalez","year":"2007","journal-title":"Nature"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"7220","DOI":"10.1073\/pnas.95.12.7220","article-title":"Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency","volume":"95","author":"N Grotz","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1016\/j.febslet.2007.03.016","article-title":"The monosaccharide transporter(-like) gene family in Arabidopsis","volume":"581","author":"M Buttner","year":"2007","journal-title":"FEBS Lett"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1016\/j.febslet.2007.04.047","article-title":"Nitrate transporters and peptide transporters","volume":"581","author":"YF Tsay","year":"2007","journal-title":"FEBS Lett"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fpls.2011.00083","article-title":"Phosphate import in plants: focus on the PHT1 transporters","volume":"2","author":"L Nussaume","year":"2011","journal-title":"Front Plant Sci"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"3285","DOI":"10.1105\/tpc.104.027078","article-title":"The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins","volume":"16","author":"C Carter","year":"2004","journal-title":"Plant Cell"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1074\/mcp.M600250-MCP200","article-title":"A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture","volume":"6","author":"M Jaquinod","year":"2007","journal-title":"Mol Cell Proteomics"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1104\/pp.109.150946","article-title":"Export of vacuolar manganese by AtNRAMP3 and AtNRAMP4 is required for optimal photosynthesis and growth under manganese deficiency","volume":"152","author":"V Lanquar","year":"2010","journal-title":"Plant Physiol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1111\/j.1365-3040.2011.02305.x","article-title":"Diversity analysis of the response to Zn within the Arabidopsis thaliana species revealed a low contribution of Zn translocation to Zn tolerance and a new role for Zn in lateral root development","volume":"34","author":"O Richard","year":"2011","journal-title":"Plant Cell Environ"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1093\/pcp\/pcp067","article-title":"A mutant strain Arabidopsis thaliana that lacks vacuolar membrane zinc transporter MTP1 revealed the latent tolerance to excessive zinc","volume":"50","author":"M Kawachi","year":"2009","journal-title":"Plant Cell Physiol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/j.1469-8137.2009.02766.x","article-title":"Arabidopsis IRT3 is a zinc-regulated and plasma membrane localized zinc\/iron transporter","volume":"182","author":"YF Lin","year":"2009","journal-title":"New Phytol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1111\/j.1574-6976.2010.00217.x","article-title":"How Saccharomyces cerevisiae copes with toxic metals and metalloids","volume":"34","author":"R Wysocki","year":"2010","journal-title":"FEMS Microbiol Rev"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/pcp\/pcd059","article-title":"Transport processes of solutes across the vacuolar membrane of higher plants","volume":"41","author":"E Martinoia","year":"2000","journal-title":"Plant Cell Physiol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"3251","DOI":"10.1073\/pnas.0913035107","article-title":"Arabidopsis V-ATPase activity at the tonoplast is required for efficient nutrient storage but not for sodium accumulation","volume":"107","author":"M Krebs","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1105\/tpc.113.117523","article-title":"Complexity of the alternative splicing landscape in plants","volume":"25","author":"AS Reddy","year":"2013","journal-title":"Plant Cell"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1105\/tpc.113.113803","article-title":"Alternative splicing at the intersection of biological timing, development, and stress responses","volume":"25","author":"D Staiger","year":"2013","journal-title":"Plant Cell"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.bbagrm.2012.08.005","article-title":"Transcriptional elongation and alternative splicing","volume":"1829","author":"G Dujardin","year":"2013","journal-title":"Biochim Biophys Acta"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"4051","DOI":"10.1242\/jcs.114.22.4051","article-title":"A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses","volume":"114","author":"YS Chun","year":"2001","journal-title":"J Cell Sci"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.1111\/febs.12318","article-title":"Zinc-induced modulation of SRSF6 activity alters Bim splicing to promote generation of the most potent apoptotic isoform BimS","volume":"280","author":"H Hara","year":"2013","journal-title":"FEBS J"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/pcp\/pcs189","article-title":"A computational and experimental approach reveals that the 5\u2032-proximal region of the 5\u2032-UTR has a Cis-regulatory signature responsible for heat stress-regulated mRNA translation in Arabidopsis","volume":"54","author":"H Matsuura","year":"2013","journal-title":"Plant Cell Physiol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1093\/nar\/gki240","article-title":"mRNA sequence features that contribute to translational regulation in Arabidopsis","volume":"33","author":"R Kawaguchi","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.1093\/jxb\/ert235","article-title":"The Arabidopsis thaliana MHX gene includes an intronic element that boosts translation when localized in a 5\u2032 UTR intron","volume":"64","author":"T Akua","year":"2013","journal-title":"J Exp Bot"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1093\/jxb\/eri097","article-title":"Expression of AtMHX, an Arabidopsis vacuolar metal transporter, is repressed by the 5\u2032 untranslated region of its gene","volume":"56","author":"O David-Assael","year":"2005","journal-title":"J Exp Bot"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1093\/pcp\/pcr001","article-title":"Sublethal cadmium intoxication in Arabidopsis thaliana impacts translation at multiple levels","volume":"52","author":"R Sormani","year":"2011","journal-title":"Plant Cell Physiol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1111\/j.1365-313X.2005.02333.x","article-title":"Cap-independent translation of maize Hsp101","volume":"41","author":"TD Dinkova","year":"2005","journal-title":"Plant J"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.gene.2008.04.008","article-title":"The 5\u2032 untranslated region of the maize alcohol dehydrogenase gene contains an internal ribosome entry site","volume":"420","author":"ES Mardanova","year":"2008","journal-title":"Gene"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1046\/j.1365-313x.1998.00343.x","article-title":"Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana","volume":"16","author":"SJ Clough","year":"1998","journal-title":"Plant J"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1399-3054.1962.tb08052.x","article-title":"A revised medium for rapid growth and bioassays with tobacco tissue culture","volume":"15","author":"T Murashige","year":"1962","journal-title":"Physiol Plant"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S1360-1385(02)02251-3","article-title":"GATEWAY vectors for Agrobacterium-mediated plant transformation","volume":"7","author":"M Karimi","year":"2002","journal-title":"Trends Plant Sci"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1101\/gad.9.14.1797","article-title":"Patterns of gene action in plant development revealed by enhancer trap and gene trap transposable elements","volume":"9","author":"V Sundaresan","year":"1995","journal-title":"Genes Dev"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/j.1469-8137.2012.04167.x","article-title":"The Pht1;9 and Pht1;8 transporters mediate inorganic phosphate acquisition by the Arabidopsis thaliana root during phosphorus starvation","volume":"195","author":"E Remy","year":"2012","journal-title":"New Phytol"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1093\/bioinformatics\/btg157","article-title":"Q-Gene: processing quantitative real-time RT-PCR data","volume":"19","author":"P Simon","year":"2003","journal-title":"Bioinformatics"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1093\/emboj\/cdf312","article-title":"A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs","volume":"21","author":"D Silhavy","year":"2002","journal-title":"EMBO J"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1046\/j.1365-313X.2003.01676.x","article-title":"An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus","volume":"33","author":"O Voinnet","year":"2003","journal-title":"Plant J"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.gene.2004.10.016","article-title":"Drag&amp;Drop cloning in yeast","volume":"344","author":"G Jansen","year":"2005","journal-title":"Gene"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1007\/s00253-009-2025-5","article-title":"Heterologous expression of a Tpo1 homolog from Arabidopsis thaliana confers resistance to the herbicide 2,4-D and other chemical stresses in yeast","volume":"84","author":"TR Cabrito","year":"2009","journal-title":"Appl Microbiol Biotechnol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/j.1365-313X.2004.02148.x","article-title":"Phenotypic characterization of a photomorphogenic mutant","volume":"39","author":"C Fankhauser","year":"2004","journal-title":"Plant J"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1365-313X.1994.00421.x","article-title":"Transient transformation of Arabidopsis leaf protoplasts: a versatile experimental system to study gene expression","volume":"5","author":"S Abel","year":"1994","journal-title":"Plant J"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3389\/fpls.2013.00197","article-title":"miRNAs mediate SnRK1-dependent energy signaling in Arabidopsis","volume":"4","author":"A Confraria","year":"2013","journal-title":"Front Plant Sci"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"UK Laemmli","year":"1970","journal-title":"Nature"},{"key":"ref76","unstructured":"Eaton AD, Clesceri LS, Rice EW, Greenberg AE, editors (2005) Standard Methods for the Examination of Water and Wastewater. 21st ed: American Public Health Association, American Water Works Association, Water Environment Federation."},{"key":"ref77","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1748-7188-6-26","article-title":"ViennaRNA Package 2.0","volume":"6","author":"R Lorenz","year":"2011","journal-title":"Algorithms Mol Biol"}],"container-title":["PLoS Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pgen.1004375","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T17:15:37Z","timestamp":1649006137000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pgen.1004375"}},"subtitle":[],"editor":[{"given":"Mark","family":"Aarts","sequence":"first","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2014,5,15]]},"references-count":77,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,5,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pgen.1004375","relation":{},"ISSN":["1553-7404"],"issn-type":[{"value":"1553-7404","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,15]]}}}