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Noguchi","year":"1999","journal-title":"J Biol Chem"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"5008","DOI":"10.1074\/jbc.M312054200","article-title":"c-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability","volume":"279","author":"D Alarcon-Vargas","year":"2004","journal-title":"J Biol Chem"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"5294","DOI":"10.1038\/sj.emboj.7601401","article-title":"JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila","volume":"25","author":"M Uhlirova","year":"2006","journal-title":"The EMBO Journal"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0167-4838(99)00279-4","article-title":"Tissue inhibitors of metalloproteinases: evolution, structure and function","volume":"1477","author":"K Brew","year":"2000","journal-title":"Biochim Biophys 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Frost","year":"1996","journal-title":"Dev Neurosci"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1002\/dneu.20966","article-title":"Glia unglued: How signals from the extracellular matrix regulate the development of myelinating glia","volume":"71","author":"H Colognato","year":"2011","journal-title":"Devel Neurobio"},{"key":"ref78","article-title":"ECM stiffness regulates glial migration in Drosophila and mammalian glioma models","author":"SN Kim","year":"2014","journal-title":"Development"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.1242\/dev.101972","article-title":"Loss of focal adhesions in glia disrupts both glial and photoreceptor axon migration in the Drosophila visual system","volume":"141","author":"X Xie","year":"2014","journal-title":"Development"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1083\/jcb.145.1.191","article-title":"wing blister, a new Drosophila laminin alpha chain required 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Rahl","year":"2010","journal-title":"Cell"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1038\/ncomms2469","article-title":"A subset of Drosophila Myc sites remain associated with mitotic chromosomes colocalized with insulator proteins","volume":"4","author":"J Yang","year":"2013","journal-title":"Nat Commun"},{"key":"ref94","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/nature13537","article-title":"Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis","volume":"511","author":"A Sab\u00f2","year":"2014","journal-title":"Nature"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.stemcr.2014.11.001","article-title":"C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells","volume":"4","author":"KY Kwan","year":"2015","journal-title":"Stem Cell Reports"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/nrn2720","article-title":"Modes and regulation of glial migration in vertebrates and invertebrates","volume":"10","author":"C Kl\u00e4mbt","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1038\/nature04829","article-title":"Social interactions among epithelial cells during tracheal branching morphogenesis","volume":"441","author":"AS Ghabrial","year":"2006","journal-title":"Nature"},{"key":"ref98","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1534\/g3.111.001495","article-title":"Genetic analysis of fibroblast growth factor signaling in the Drosophila eye","volume":"2","author":"T Mukherjee","year":"2012","journal-title":"G3 (Bethesda)"},{"key":"ref99","article-title":"The extracellular matrix niche microenvironment of neural and cancer stem cells in the brain","author":"J Reinhard","year":"2016","journal-title":"Int J Biochem Cell Biol"},{"key":"ref100","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/sj.cr.7290262","article-title":"Role of JNK activation in apoptosis: a double-edged sword","volume":"15","author":"J Liu","year":"2005","journal-title":"Cell Res"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1016-8478(23)12876-7","article-title":"JNK regulation of oncogenesis","volume":"21","author":"LE Heasley","year":"2006","journal-title":"Mol Cells"},{"key":"ref102","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1083\/jcb.201103153","article-title":"DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity","volume":"194","author":"AS Ghosh","year":"2011","journal-title":"The Journal of Cell Biology"},{"key":"ref103","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.neures.2011.07.1830","article-title":"c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice","volume":"71","author":"K Yoshimura","year":"2011","journal-title":"Neurosci Res"},{"key":"ref104","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.nbd.2012.02.003","article-title":"JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death","volume":"46","author":"KA Fernandes","year":"2012","journal-title":"Neurobiol Dis"},{"key":"ref105","doi-asserted-by":"crossref","first-page":"E3696","DOI":"10.1073\/pnas.1216204109","article-title":"SCG10 is a JNK target in the axonal degeneration pathway","volume":"109","author":"JE Shin","year":"2012","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref106","doi-asserted-by":"crossref","first-page":"6199","DOI":"10.1038\/srep06199","article-title":"Axon injury and regeneration in the adult Drosophila","volume":"4","author":"L Soares","year":"2014","journal-title":"Sci Rep"},{"key":"ref107","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.mcn.2004.07.001","article-title":"Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons","volume":"27","author":"C Lindwall","year":"2004","journal-title":"Mol Cell Neurosci"},{"key":"ref108","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.expneurol.2005.07.022","article-title":"The Janus role of c-Jun: cell death versus survival and regeneration of neonatal sympathetic and sensory neurons","volume":"196","author":"C Lindwall","year":"2005","journal-title":"Exp Neurol"},{"key":"ref109","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1083\/jcb.201006039","article-title":"Protein turnover of the Wallenda\/DLK kinase regulates a retrograde response to axonal injury","volume":"191","author":"X Xiong","year":"2010","journal-title":"The Journal of Cell Biology"},{"key":"ref110","doi-asserted-by":"crossref","first-page":"e1649","DOI":"10.1038\/cddis.2015.27","article-title":"JNK pathway activation is able to synchronize neuronal death and glial phagocytosis in Drosophila","volume":"6","author":"J Shklover","year":"2015","journal-title":"Cell Death Dis"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1002\/glia.22577","article-title":"Traumatic scratch injury in astrocytes triggers calcium influx to activate the JNK\/c-Jun\/AP-1 pathway and switch on GFAP expression","volume":"61","author":"K Gao","year":"2013","journal-title":"Glia"},{"key":"ref112","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1529-8027.2008.00168.x","article-title":"Novel signals controlling embryonic Schwann cell development, myelination and dedifferentiation","volume":"13","author":"R Mirsky","year":"2008","journal-title":"J Peripher Nerv Syst"},{"key":"ref113","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1083\/jcb.201503019","article-title":"Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves","volume":"210","author":"JA Gomez-Sanchez","year":"2015","journal-title":"The Journal of Cell Biology"},{"key":"ref114","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/glia.20173","article-title":"-Jun N-terminal kinases (JNKs) mediate pro-inflammatory actions of microglia","volume":"50","author":"V Waetzig","year":"2005","journal-title":"Glia"},{"key":"ref115","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.mod.2009.06.1082","article-title":"JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy","volume":"126","author":"H Wu","year":"2009","journal-title":"MECHANISMS OF DEVELOPMENT"},{"key":"ref116","article-title":"Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory Response","author":"H Weavers","year":"2016","journal-title":"Cell"},{"key":"ref117","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1002\/stem.2095","article-title":"Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation","volume":"33","author":"A Tassoni","year":"2015","journal-title":"Stem Cells"},{"key":"ref118","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2015.06.003","article-title":"Glia-neuron interactions in the mammalian retina","volume":"51","author":"E Vecino","year":"2016","journal-title":"Prog Retin Eye Res"},{"key":"ref119","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0092-8674(03)00848-1","article-title":"Homothorax switches function of Drosophila photoreceptors from color to polarized light sensors","volume":"115","author":"MF Wernet","year":"2003","journal-title":"Cell"},{"key":"ref120","doi-asserted-by":"crossref","first-page":"4881","DOI":"10.1242\/dev.02669","article-title":"Direct control of neurogenesis by selector factors in the fly eye: regulation of atonal by Ey and So","volume":"133","author":"T Zhang","year":"2006","journal-title":"Development"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"18977","DOI":"10.1073\/pnas.1103242108","article-title":"Conserved metabolic energy production pathways govern Eiger\/TNF-induced nonapoptotic cell death","volume":"108","author":"H Kanda","year":"2011","journal-title":"Proc Natl Acad Sci USA"}],"updated-by":[{"DOI":"10.1371\/journal.pgen.1006647","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T00:00:00Z","timestamp":1490054400000}}],"container-title":["PLOS 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