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Woodring","year":"2009","journal-title":"Physiological Entomology"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"5892","DOI":"10.1093\/emboj\/18.21.5892","article-title":"Reverse physiology in drosophila: identification of a novel allatostatin-like neuropeptide and its cognate receptor structurally related to the mammalian somatostatin\/galanin\/opioid receptor family","volume":"18","author":"N Birgul","year":"1999","journal-title":"EMBO J"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.peptides.2012.05.016","article-title":"Galanin and its receptors: a novel strategy for appetite control and obesity therapy","volume":"36","author":"P Fang","year":"2012","journal-title":"Peptides"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1006\/bbrc.2000.2251","article-title":"Molecular cloning and genomic organization of a novel receptor from Drosophila melanogaster structurally related to mammalian galanin 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A"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1210\/en.2013-2106","article-title":"Coevolution of the spexin\/galanin\/kisspeptin family: Spexin activates galanin receptor type II and III","volume":"155","author":"DK Kim","year":"2014","journal-title":"Endocrinology"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1006\/bbrc.2001.4659","article-title":"Structural, functional, and evolutionary characterization of novel members of the allatostatin receptor family from insects","volume":"282","author":"L Auerswald","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1006\/bbrc.2000.2964","article-title":"Molecular cloning and genomic organization of a second probable allatostatin receptor from Drosophila melanogaster","volume":"273","author":"C Lenz","year":"2000","journal-title":"Biochem Biophys Res 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Abdel-latief","year":"2014","journal-title":"Peptides"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.pt.2008.12.009","article-title":"Comparison of Caenorhabditis elegans NLP peptides with arthropod neuropeptides","volume":"25","author":"SJ Husson","year":"2009","journal-title":"Trends Parasitol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"14000","DOI":"10.1073\/pnas.241231298","article-title":"Identification of neuropeptide-like protein gene families in Caenorhabditiselegans and other species","volume":"98","author":"AN Nathoo","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/ng2049","article-title":"Using FlyAtlas to identify better Drosophila melanogaster models of human disease","volume":"39","author":"VR Chintapalli","year":"2007","journal-title":"Nat Genet"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2583.2006.00610.x","article-title":"Genome-wide analysis of gene expression in adult Anopheles gambiae","volume":"15","author":"O Marinotti","year":"2006","journal-title":"Insect Mol Biol"},{"key":"ref58","author":"S Manguin","year":"2008"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"246","DOI":"10.11646\/zootaxa.3619.3.2","article-title":"Anopheles coluzzii and Anopheles amharicus, new members of the Anopheles gambiae complex","volume":"3619","author":"M Coetzee","year":"2013","journal-title":"Zootaxa"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1126\/science.1195755","article-title":"Widespread Divergence Between Incipient Anopheles gambiae Species Revealed by Whole Genome Sequences","volume":"330","author":"MKN 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Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes","volume":"347","author":"DE Neafsey","year":"2015","journal-title":"Science"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"e10592","DOI":"10.1371\/journal.pone.0010592","article-title":"Genome landscape and evolutionary plasticity of chromosomes in malaria mosquitoes","volume":"5","author":"A Xia","year":"2010","journal-title":"PLoS One"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1046\/j.1365-2583.2001.00235.x","article-title":"Molecular evidence of incipient speciation within Anopheles gambiae s.s. in West Africa","volume":"10","author":"A della Torre","year":"2001","journal-title":"Insect Mol Biol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1126\/science.1076181","article-title":"The genome sequence of the malaria mosquito Anopheles gambiae","volume":"298","author":"RA Holt","year":"2002","journal-title":"Science"},{"key":"ref66","unstructured":"Nicholas KB, Nicholas HBJ (1997) Genedoc: a tool for editing and annotating multiple sequence alignments. Distributd by the author."},{"key":"ref67","doi-asserted-by":"crossref","first-page":"e48931","DOI":"10.1371\/journal.pone.0048931","article-title":"Multiple kisspeptin receptors in early osteichthyans provide new insights into the evolution of this receptor family","volume":"7","author":"J Pasquier","year":"2012","journal-title":"PLoS One"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1093\/bioinformatics\/bti263","article-title":"ProtTest: selection of best-fit models of protein evolution","volume":"21","author":"F Abascal","year":"2005","journal-title":"Bioinformatics"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"783","DOI":"10.2307\/2408678","article-title":"Confidence Limits on Phylogenies: An Approach Using the Bootstrap","volume":"39","author":"J Felsenstein","year":"1985","journal-title":"Evolution"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/sysbio\/syq010","article-title":"New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0","volume":"59","author":"S Guindon","year":"2010","journal-title":"Syst Biol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1080\/10635150600755453","article-title":"Approximate likelihood-ratio test for branches: A fast, accurate, and powerful alternative","volume":"55","author":"M Anisimova","year":"2006","journal-title":"Syst Biol"},{"key":"ref72","first-page":"406","article-title":"The neighbor-joining method: a new method for reconstructing phylogenetic trees","volume":"4","author":"N Saitou","year":"1987","journal-title":"Mol Biol Evol"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"K Tamura","year":"2011","journal-title":"Mol Biol Evol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3389\/fendo.2012.00173","article-title":"Comparative evolutionary histories of kisspeptins and kisspeptin receptors in vertebrates reveal both parallel and divergent features","volume":"3","author":"J Pasquier","year":"2012","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1046\/j.1365-2583.2000.00159.x","article-title":"Characterization of a carboxypeptidase A gene from the mosquito, Aedes aegypti","volume":"9","author":"MJ Edwards","year":"2000","journal-title":"Insect Mol Biol"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ibmb.2005.02.013","article-title":"Nutritional regulation of vitellogenesis in mosquitoes: implications for anautogeny","volume":"35","author":"GM Attardo","year":"2005","journal-title":"Insect Biochem Mol Biol"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/1471-2164-11-312","article-title":"Plasmodium infection alters Anopheles gambiae detoxification gene expression","volume":"11","author":"RC Felix","year":"2010","journal-title":"BMC Genomics"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"e24181","DOI":"10.1371\/journal.pone.0024181","article-title":"The interplay between tubulins and P450 cytochromes during Plasmodium berghei invasion of Anopheles gambiae midgut","volume":"6","author":"RC Felix","year":"2011","journal-title":"PLoS One"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.immuni.2006.08.019","article-title":"Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei","volume":"25","author":"C Frolet","year":"2006","journal-title":"Immunity"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1006\/bbrc.2000.3062","article-title":"Molecular cloning and genomic organization of an allatostatin preprohormone from Drosophila melanogaster","volume":"273","author":"C Lenz","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0196-9781(97)00032-6","article-title":"Identification of three allatostatins and their cDNA from the mosquito Aedes aegypti","volume":"18","author":"JA Veenstra","year":"1997","journal-title":"Peptides"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.mce.2008.11.017","article-title":"Evidence for two distinct KiSS genes in non-placental vertebrates that encode kisspeptins with different gonadotropin-releasing activities in fish and mammals","volume":"312","author":"A Felip","year":"2009","journal-title":"Mol Cell Endocrinol"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1021\/pr101116g","article-title":"Peptidomics and peptide hormone processing in the Drosophila midgut","volume":"10","author":"W Reiher","year":"2011","journal-title":"J Proteome Res"},{"key":"ref84","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1126\/science.1077769","article-title":"A polytene chromosome analysis of the Anopheles gambiae species complex","volume":"298","author":"M Coluzzi","year":"2002","journal-title":"Science"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1126\/science.1076827","article-title":"Neuropeptides and peptide hormones in Anopheles gambiae","volume":"298","author":"MA Riehle","year":"2002","journal-title":"Science"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.pneurobio.2010.04.010","article-title":"Drosophila neuropeptides in regulation of physiology and behavior","volume":"92","author":"DR Nassel","year":"2010","journal-title":"Prog Neurobiol"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1073\/pnas.0435715100","article-title":"Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation","volume":"100","author":"O Fritze","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref88","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1124\/mol.106.029470","article-title":"The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state","volume":"71","author":"GE Rovati","year":"2007","journal-title":"Mol Pharmacol"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/j.1460-2075.1996.tb00354.x","article-title":"Delineation of the peptide binding site of the human galanin receptor","volume":"15","author":"K Kask","year":"1996","journal-title":"EMBO J"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/nrendo.2011.20","article-title":"G protein-coupled receptors: mutations and endocrine diseases","volume":"7","author":"G Vassart","year":"2011","journal-title":"Nat Rev Endocrinol"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.bmcl.2005.09.054","article-title":"Design and synthesis of downsized metastin (45\u201354) analogs with maintenance of high GPR54 agonistic activity","volume":"16","author":"A Niida","year":"2006","journal-title":"Bioorg Med Chem Lett"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2148-6-7","article-title":"Genome-wide acceleration of protein evolution in flies (Diptera)","volume":"6","author":"J Savard","year":"2006","journal-title":"BMC Evol Biol"},{"key":"ref93","doi-asserted-by":"crossref","first-page":"e92220","DOI":"10.1371\/journal.pone.0092220","article-title":"Nematode and arthropod genomes provide new insights into the evolution of class 2 B1 GPCRs","volume":"9","author":"JC Cardoso","year":"2014","journal-title":"PLoS One"},{"key":"ref94","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/nature06784","article-title":"The genome of the model beetle and pest Tribolium castaneum","volume":"452","author":"S Richards","year":"2008","journal-title":"Nature"},{"key":"ref95","doi-asserted-by":"crossref","first-page":"R242","DOI":"10.1186\/gb-2007-8-11-r242","article-title":"Quantification of ortholog losses in insects and vertebrates","volume":"8","author":"S Wyder","year":"2007","journal-title":"Genome Biol"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/0022-1910(95)00008-I","article-title":"The Effect of the 13 Dip-Allatostatins on Myogenic and Induced Contractions of the Cockroach (Diploptera-Punctata) Hindgut","volume":"41","author":"AB Lange","year":"1995","journal-title":"Journal of Insect Physiology"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0022-1910(99)00175-4","article-title":"Biological activities of the allatostatin family of peptides in the cockroach, Diploptera punctata, and potential interactions with receptors","volume":"46","author":"SS Tobe","year":"2000","journal-title":"J Insect Physiol"},{"key":"ref98","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1054\/npep.1999.0049","article-title":"The role of galanin in feeding behavior","volume":"33","author":"JN Crawley","year":"1999","journal-title":"Neuropeptides"},{"key":"ref99","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/07391102.2010.10507346","article-title":"Evolution of galanin receptor genes: insights from the deuterostome genomes","volume":"28","author":"Z Liu","year":"2010","journal-title":"J Biomol Struct Dyn"},{"key":"ref100","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.bbrc.2003.11.066","article-title":"The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system","volume":"312","author":"S Funes","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1056\/NEJMoa035322","article-title":"The GPR54 gene as a regulator of puberty","volume":"349","author":"SB Seminara","year":"2003","journal-title":"N Engl J Med"},{"key":"ref102","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.peptides.2008.06.007","article-title":"KiSS-1\/kisspeptins and the metabolic control of reproduction: physiologic roles and putative physiopathological implications","volume":"30","author":"JM Castellano","year":"2009","journal-title":"Peptides"},{"key":"ref103","doi-asserted-by":"crossref","first-page":"4601","DOI":"10.1210\/en.2007-0500","article-title":"Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line","volume":"148","author":"RM Luque","year":"2007","journal-title":"Endocrinology"},{"key":"ref104","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.mce.2007.10.011","article-title":"KiSS-1 mRNA in adipose tissue is regulated by sex hormones and food intake","volume":"281","author":"RE Brown","year":"2008","journal-title":"Mol Cell Endocrinol"},{"key":"ref105","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.metabol.2013.01.015","article-title":"Kisspeptin as a link between metabolism and reproduction: evidences from rodent and primate studies","volume":"62","author":"F Wahab","year":"2013","journal-title":"Metabolism"},{"key":"ref106","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.ibmb.2014.09.001","article-title":"Mode of action of allatostatins in the regulation of juvenile hormone biosynthesis in the cockroach, Diploptera punctata","volume":"54","author":"J Huang","year":"2014","journal-title":"Insect Biochem Mol Biol"},{"key":"ref107","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.jinsphys.2008.04.018","article-title":"Quantification of allatostatin receptor mRNA levels in the cockroach, Diploptera punctata, using real-time PCR","volume":"54","author":"P Lungchukiet","year":"2008","journal-title":"J Insect Physiol"},{"key":"ref108","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.peptides.2004.08.026","article-title":"Immunocytochemical analysis of putative allatostatin receptor (DAR-2) distribution in the CNS of larval Drosophila melanogaster","volume":"26","author":"PR Bowser","year":"2005","journal-title":"Peptides"},{"key":"ref109","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1186\/1471-2164-12-296","article-title":"A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae","volume":"12","author":"DA Baker","year":"2011","journal-title":"BMC Genomics"},{"key":"ref110","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/S0965-1748(97)00093-3","article-title":"Rapid induction by a blood meal of a carboxypeptidase gene in the gut of the mosquito Anopheles gambiae","volume":"27","author":"MJ Edwards","year":"1997","journal-title":"Insect Biochem Mol Biol"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1365-2583.2005.00535.x","article-title":"The accumulation of specific mRNAs following multiple blood meals in Anopheles gambiae","volume":"14","author":"X Nirmala","year":"2005","journal-title":"Insect Mol Biol"},{"key":"ref112","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1471-2164-6-5","article-title":"Gene expression patterns associated with blood-feeding in the malaria mosquito Anopheles gambiae","volume":"6","author":"AN Dana","year":"2005","journal-title":"BMC 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