{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T17:03:11Z","timestamp":1772211791237,"version":"3.50.1"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T00:00:00Z","timestamp":1628121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/00276\/2020"],"award-info":[{"award-number":["UIDB\/00276\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["MARE\/UIDB\/MAR\/04292\/2020"],"award-info":[{"award-number":["MARE\/UIDB\/MAR\/04292\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["MARE\/UIDP\/MAR\/04292\/2020"],"award-info":[{"award-number":["MARE\/UIDP\/MAR\/04292\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Lisbon","award":["C10571K"],"award-info":[{"award-number":["C10571K"]}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/00006\/2020"],"award-info":[{"award-number":["UIDB\/00006\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>\n                    Assessments regarding health aspects of Iberian leuciscids are limited. There is currently an information gap regarding effects of infectious diseases on these populations and their role as a possible conservation threat. Moreover, differences in susceptibility to particular agents, such as\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    spp., by different species\/populations is not clear. To understand potential differences in\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    diversity and load, as well as in the prevalence and proportion of skin lesions, in fishes exposed to similar environmental conditions, an observational study was implemented. Using a set of 12 individuals belonging to two sympatric Iberian leuciscid species (\n                    <jats:italic>Squalius pyrenaicus<\/jats:italic>\n                    and\n                    <jats:italic>Iberochondrostoma lusitanicum<\/jats:italic>\n                    ), the skin lesion score in each individual was analyzed. Furthermore, a bacterial collection of\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    spp. isolated from each individual was created and isolates\u2019 load was quantified by plate counting, identified at species level using a multiplex-PCR assay and virulence profiles established using classical phenotypic methods. The similarity relationships of the isolates were evaluated using a RAPD analysis. The skin lesion score was significantly higher in\n                    <jats:italic>S<\/jats:italic>\n                    .\n                    <jats:italic>pyrenaicus<\/jats:italic>\n                    , while the\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    spp. load did not differ between species. When analyzing\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    species diversity between fishes, different patterns were observed. A predominance of\n                    <jats:italic>A<\/jats:italic>\n                    .\n                    <jats:italic>hydrophila<\/jats:italic>\n                    was detected in\n                    <jats:italic>S<\/jats:italic>\n                    .\n                    <jats:italic>pyrenaicus<\/jats:italic>\n                    individuals, while\n                    <jats:italic>I<\/jats:italic>\n                    .\n                    <jats:italic>lusitanicum<\/jats:italic>\n                    individuals displayed a more diverse structure. Similarly, the virulence index of isolates from\n                    <jats:italic>S<\/jats:italic>\n                    .\n                    <jats:italic>pyrenaicus<\/jats:italic>\n                    was higher, mostly due to the isolated\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    species. Genomic typing clustered the isolates mainly by fish species and skin lesion score. Specific\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    clusters were associated with higher virulence indexes. Current results suggest potential differences in susceptibility to\n                    <jats:italic>Aeromonas<\/jats:italic>\n                    spp. at the fish species\/individual level, and constitute important knowledge for proper wildlife management through the signalization of at-risk fish populations and hierarchization of conservation measures.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0255850","type":"journal-article","created":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T14:06:17Z","timestamp":1628172377000},"page":"e0255850","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Sympatric threatened Iberian leuciscids exhibit differences in Aeromonas diversity and skin lesions\u2019 prevalence"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7364-821X","authenticated-orcid":true,"given":"Miguel L.","family":"Grilo","sequence":"first","affiliation":[]},{"given":"L\u00e9lia","family":"Chambel","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2581-1972","authenticated-orcid":true,"given":"Tiago A.","family":"Marques","sequence":"additional","affiliation":[]},{"given":"Carla","family":"Sousa-Santos","sequence":"additional","affiliation":[]},{"given":"Joana I.","family":"Robalo","sequence":"additional","affiliation":[]},{"given":"Manuela","family":"Oliveira","sequence":"additional","affiliation":[]}],"member":"340","published-online":{"date-parts":[[2021,8,5]]},"reference":[{"key":"pone.0255850.ref001","first-page":"1","volume-title":"Conservation of Freshwater Fishes","author":"W Darwall","year":"2015"},{"key":"pone.0255850.ref002","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/brv.12480","article-title":"Emerging threats and persistent conservation challenges for freshwater biodiversity","volume":"94","author":"AJ Reid","year":"2019","journal-title":"Biol. 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