{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T18:03:44Z","timestamp":1791655424086,"version":"4.3.4"},"reference-count":19,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1378\/chest.06-1467","type":"journal-article","created":{"date-parts":[[2007,4,10]],"date-time":"2007-04-10T13:40:59Z","timestamp":1176212459000},"page":"1173-1180","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":215,"title":["Serum Indicators for the Diagnosis of Pneumocystis Pneumonia"],"prefix":"10.1016","volume":"131","author":[{"given":"Sadatomo","family":"Tasaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wakako","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyasu","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akitoshi","family":"Ishizaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1378\/chest.06-1467_bib1","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1056\/NEJMra032588","article-title":"Pneumocystis pneumonia","volume":"350","author":"Thomas","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.06-1467_bib2","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1183\/09031936.93.03080939","article-title":"Side-effects and safety of BAL","volume":"3","author":"Klech","year":"1990","journal-title":"Eur Respir J"},{"key":"10.1378\/chest.06-1467_bib3","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1378\/chest.108.2.415","article-title":"Serum lactate dehydrogenase in Pneumocystis carinii pneumonia, tuberculosis, and bacterial pneumonia","volume":"108","author":"Quist","year":"1995","journal-title":"Chest"},{"key":"10.1378\/chest.06-1467_bib4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0140-6736(95)91152-9","article-title":"Plasma (1\u2013>3)-\u03b2-D-glucan measurement in diagnosis of invasive deep mycosis and fungal febrile episodes","volume":"345","author":"Obayashi","year":"1995","journal-title":"Lancet"},{"key":"10.1378\/chest.06-1467_bib5","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1128\/cdli.3.2.197-199.1996","article-title":"(1\u21923) \u03b2-D-glucan as a quantitative serological marker for Pneumocystis carinii pneumonia","volume":"3","author":"Yasuoka","year":"1996","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1378\/chest.06-1467_bib6","first-page":"678","article-title":"(1\u21923) \u03b2-D glucan is a diagnostic and negative prognostic marker for Pneumocystis carinii pneumonia in patients with connective tissue disease","volume":"23","author":"Shimizu","year":"2005","journal-title":"Clin Exp Rheumatol"},{"key":"10.1378\/chest.06-1467_bib7","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1378\/chest.96.1.68","article-title":"New serum indicator of interstitial pneumonitis activity: sialylated carbohydrate antigen KL-6","volume":"96","author":"Kohno","year":"1989","journal-title":"Chest"},{"key":"10.1378\/chest.06-1467_bib8","doi-asserted-by":"crossref","first-page":"L1088","DOI":"10.1152\/ajplung.00420.2002","article-title":"Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in the acute respiratory distress syndrome","volume":"286","author":"Ishizaka","year":"2004","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1378\/chest.06-1467_bib9","doi-asserted-by":"crossref","first-page":"307","DOI":"10.2169\/internalmedicine.37.307","article-title":"KL-6 as a serologic indicator of Pneumocystis carinii pneumonia in immunocompromised hosts","volume":"37","author":"Hamada","year":"1998","journal-title":"Intern Med"},{"key":"10.1378\/chest.06-1467_bib10","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/10245330290022133","article-title":"Elevation of serum KL-6 levels in patients with hematological malignancies associated with cytomegalovirus or Pneumocystis carinii pneumonia","volume":"7","author":"Tanaka","year":"2002","journal-title":"Hematology"},{"key":"10.1378\/chest.06-1467_bib11","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/BF01781104","article-title":"Detection of Pneumocystis carinii with direct fluorescence antibody and Calcofluor white stain","volume":"24","author":"Aslanzadeh","year":"1996","journal-title":"Infection"},{"key":"10.1378\/chest.06-1467_bib12","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2307\/2531595","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong","year":"1988","journal-title":"Biometrics"},{"key":"10.1378\/chest.06-1467_bib13","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0140-6736(03)12984-4","article-title":"S-adenosylmethionine concentrations in diagnosis of Pneumocystis carinii pneumonia","volume":"361","author":"Skelly","year":"2003","journal-title":"Lancet"},{"key":"10.1378\/chest.06-1467_bib14","doi-asserted-by":"crossref","first-page":"21S","DOI":"10.1111\/j.1550-7408.1989.tb02674.x","article-title":"Yeast glucan in the cyst wall of Pneumocystis carinii.","volume":"36","author":"Matsumoto","year":"1989","journal-title":"J Protozool"},{"key":"10.1378\/chest.06-1467_bib15","doi-asserted-by":"crossref","first-page":"3932","DOI":"10.4049\/jimmunol.150.9.3932","article-title":"Pneumocystis carinii stimulates tumor necrosis factor-\u03b1 release from alveolar macrophages through a \u03b2-glucan\u2013mediated mechanism","volume":"150","author":"Hoffman","year":"1993","journal-title":"J Immunol"},{"key":"10.1378\/chest.06-1467_bib16","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1378\/chest.93.1.60","article-title":"Correlation of bronchoalveolar lavage cell populations with clinical severity of Pneumocystis carinii pneumonia","volume":"93","author":"Smith","year":"1988","journal-title":"Chest"},{"key":"10.1378\/chest.06-1467_bib17","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1136\/thorax.58.7.594","article-title":"Asymptomatic carriage of Pneumocystis jiroveci in subjects undergoing bronchoscopy: a prospective study","volume":"58","author":"Maskell","year":"2003","journal-title":"Thorax"},{"key":"10.1378\/chest.06-1467_bib18","doi-asserted-by":"crossref","first-page":"3409","DOI":"10.1128\/JCM.37.10.3409-3410.1999","article-title":"Pneumocystis carinii carriage in immunocompetent patients with primary pulmonary disorders as detected by single or nested PCR","volume":"37","author":"Sing","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.1378\/chest.06-1467_bib19","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1128\/JCM.42.7.3333-3335.2004","article-title":"Detection of Pneumocystis jiroveci in respiratory specimens by four staining methods","volume":"42","author":"Procop","year":"2004","journal-title":"J Clin Microbiol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215490476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215490476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T07:24:27Z","timestamp":1757921067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215490476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["S0012369215490476"],"URL":"https:\/\/doi.org\/10.1378\/chest.06-1467","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum Indicators for the Diagnosis of Pneumocystis Pneumonia","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.06-1467","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}