{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:56:22Z","timestamp":1773323782367,"version":"3.50.1"},"reference-count":83,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1378\/chest.07-1384","type":"journal-article","created":{"date-parts":[[2007,9,14]],"date-time":"2007-09-14T18:23:17Z","timestamp":1189794197000},"page":"314S-323S","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"special_numbering":"S","title":["Evidence for Management of Small Cell Lung Cancer"],"prefix":"10.1016","volume":"132","author":[{"given":"David J.","family":"Samson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome","family":"Seidenfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George R.","family":"Simon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"Andrew T.","family":"Turrisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Bonnell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen M.","family":"Ziegler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Aronson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1378\/chest.07-1384_bib2","first-page":"810","article-title":"Small cell lung cancer","author":"Murren","year":"2005"},{"key":"10.1378\/chest.07-1384_bib3","doi-asserted-by":"crossref","first-page":"259S","DOI":"10.1378\/chest.123.1_suppl.259S","article-title":"American College of Chest Physicians. Small cell lung cancer","volume":"123(suppl)","author":"Simon","year":"2003","journal-title":"Chest"},{"key":"10.1378\/chest.07-1384_bib5","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ctrv.2004.06.003","article-title":"Recent advances in management of small-cell lung cancer","volume":"30","author":"Chua","year":"2004","journal-title":"Cancer Treat Rev"},{"key":"10.1378\/chest.07-1384_bib6","first-page":"3","article-title":"Overview and state of the art in the management of lung cancer","volume":"18(suppl 4)","author":"Ettinger","year":"2004","journal-title":"Oncology (Huntingt)"},{"key":"10.1378\/chest.07-1384_bib7","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.lungcan.2003.12.006","article-title":"Small cell lung cancer: state of the art and future perspectives","volume":"45","author":"Stupp","year":"2004","journal-title":"Lung Cancer"},{"key":"10.1378\/chest.07-1384_bib9","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1183\/09031936.01.00266101","article-title":"Chemotherapy in small cell lung cancer","volume":"18","author":"Osterlind","year":"2001","journal-title":"Eur Respir J"},{"key":"10.1378\/chest.07-1384_bib10","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1200\/JCO.1992.10.6.890","article-title":"Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-analysis","volume":"10","author":"Warde","year":"1992","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib11","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1056\/NEJM199212033272302","article-title":"A meta-analysis of thoracic radiotherapy for small-cell lung cancer","volume":"327","author":"Pignon","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.07-1384_bib12","first-page":"36","article-title":"Platinum combined with radiation therapy in small cell lung cancer: focusing like a laser beam on crucial issues","volume":"21(suppl)","author":"Turrisi","year":"1994","journal-title":"Semin Oncol"},{"key":"10.1378\/chest.07-1384_bib14","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1634\/theoncologist.9-6-665","article-title":"A meta-analysis of the timing of chest irradiation in the combined modality treatment of limited-stage small cell lung cancer","volume":"9","author":"Huncharek","year":"2004","journal-title":"Oncologist"},{"key":"10.1378\/chest.07-1384_bib15","doi-asserted-by":"crossref","unstructured":"Pijls-Johannesma MCG, De Ruysscher D, Lambin P, et al. Early vs late chest radiotherapy for limited stage small cell lung cancer. Cochrane Database Syst Rev (database online). Issue 4, 2004","DOI":"10.1002\/14651858.CD004700"},{"key":"10.1378\/chest.07-1384_bib16","doi-asserted-by":"crossref","first-page":"4837","DOI":"10.1200\/JCO.2004.01.178","article-title":"Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer","volume":"22","author":"Fried","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib17","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1200\/JCO.1984.2.6.585","article-title":"Combined modality treatment of extensive small cell lung cancer: a Southwest Oncology Group study","volume":"2","author":"Livingston","year":"1984","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib18","first-page":"1395","article-title":"Combined alkylators and multiple-site irradiation for extensive small cell lung cancer: a Southwest Oncology Group Study","volume":"70","author":"Livingston","year":"1986","journal-title":"Cancer Treat Rep"},{"key":"10.1378\/chest.07-1384_bib19","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1056\/NEJM199908123410711","article-title":"Prophylactic cranial irradiation and small-cell lung cancer","volume":"341","author":"Carney","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.07-1384_bib20","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0749-3797(01)00261-6","article-title":"Current methods of the US Preventive Services Task Force: a review of the process","volume":"20(suppl)","author":"Harris","year":"2001","journal-title":"Am J Prev Med"},{"key":"10.1378\/chest.07-1384_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta8250","article-title":"Development and validation of methods for assessing the quality of diagnostic accuracy studies","volume":"8","author":"Whiting","year":"2004","journal-title":"Health Technol Assess"},{"key":"10.1378\/chest.07-1384_bib22","author":"Seidenfeld","year":"2006","journal-title":"Management of small cell lung cancer: evidence report\/technology assessment No. 143; prepared by Blue Cross and Blue Shield Association Technology Evaluation Center Evidence-Based Practice Center under contract 290-02-0026"},{"key":"10.1378\/chest.07-1384_bib23","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.1200\/JCO.2002.12.071","article-title":"Phase III study of concurrent vs sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: results of the Japan Clinical Oncology Group Study 9104","volume":"20","author":"Takada","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib24","doi-asserted-by":"crossref","first-page":"903","DOI":"10.4046\/trd.1996.43.6.903","article-title":"The effects according to the timing of thoracic radiotherapy in limited stage small cell lung cancer","volume":"43","author":"Park","year":"1996","journal-title":"Tuberc Respir Dis"},{"key":"10.1378\/chest.07-1384_bib25","first-page":"222","article-title":"Prospective multimodality treatment of SCLC: experience during the past 18 years","volume":"22(suppl)","author":"Sun","year":"1995","journal-title":"Gan To Kagaku Ryoho"},{"key":"10.1378\/chest.07-1384_bib26","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1200\/JCO.1997.15.8.2840","article-title":"Randomized trial of alternating vs sequential radiotherapy\/chemotherapy in limited-disease patients with small-cell lung cancer: a European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group Study","volume":"15","author":"Gregor","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib27","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1378\/chest.104.3.726","article-title":"A randomized trial of delayed thoracic radiotherapy in complete responder patients with small-cell lung cancer: petites Cellules Group","volume":"104","author":"Lebeau","year":"1993","journal-title":"Chest"},{"key":"10.1378\/chest.07-1384_bib28","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3816\/CLC.2005.n.007","article-title":"Split-course vs continuous thoracic radiation therapy for limited-stage small-cell lung cancer: final report of a randomized phase III trial","volume":"6","author":"Blackstock","year":"2005","journal-title":"Clin Lung Cancer"},{"key":"10.1378\/chest.07-1384_bib29","doi-asserted-by":"crossref","first-page":"3030","DOI":"10.1200\/JCO.1997.15.9.3030","article-title":"Randomized study of initial vs late chest irradiation combined with chemotherapy in limited-stage small-cell lung cancer: Aarhus Lung Cancer Group","volume":"15","author":"Work","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib30","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/0959-8049(95)00597-8","article-title":"Prophylactic cranial irradiation in limited stage small cell lung cancer: survival benefit in patients with favourable characteristics","volume":"32A","author":"Work","year":"1996","journal-title":"Eur J Cancer"},{"key":"10.1378\/chest.07-1384_bib31","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1200\/JCO.1993.11.2.336","article-title":"Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer: the National Cancer Institute of Canada Clinical Trials Group","volume":"11","author":"Murray","year":"1993","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib32","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0360-3016(94)90058-2","article-title":"Patterns of failure following loco-regional radiotherapy in the treatment of limited stage small cell lung cancer","volume":"28","author":"Coy","year":"1994","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1378\/chest.07-1384_bib33","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1159\/000416205","article-title":"Complications of treatment of small cell carcinoma of the lung: experience from a recent Canadian trial","volume":"41","author":"Feld","year":"1988","journal-title":"Antibiot Chemother"},{"key":"10.1378\/chest.07-1384_bib34","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1056\/NEJM198704093161504","article-title":"Chemotherapy with or without radiation therapy in limited small-cell carcinoma of the lung","volume":"316","author":"Perry","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.07-1384_bib35","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000288922","article-title":"Quality of life in patients with limited small-cell carcinoma of the lung receiving chemotherapy with or without radiation therapy, for cancer and leukemia group B","volume":"62","author":"Ahles","year":"1994","journal-title":"Psychother Psychosom"},{"key":"10.1378\/chest.07-1384_bib36","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1200\/JCO.1998.16.7.2466","article-title":"Thoracic radiation therapy added to chemotherapy for small-cell lung cancer: an update of Cancer and Leukemia Group B Study 8083","volume":"16","author":"Perry","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib37","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1200\/JCO.1997.15.3.893","article-title":"Initial vs delayed accelerated hyperfractionated radiation therapy and concurrent chemotherapy in limited small-cell lung cancer: a randomized study","volume":"15","author":"Jeremic","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib38","first-page":"237","article-title":"Concurrent radiotherapy combined with carboplatin and etoposide in limited stage small cell lung cancer","volume":"27","author":"Qiao","year":"2004","journal-title":"Zhonghua Jie He He Hu Xi Za Zhi"},{"key":"10.1378\/chest.07-1384_bib39","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1023\/A:1012295131640","article-title":"Randomized comparison of early vs late hyperfractionated thoracic irradiation concurrently with chemotherapy in limited disease small-cell lung cancer: a randomized phase II study of the Hellenic Cooperative Oncology Group (HeCOG)","volume":"12","author":"Skarlos","year":"2001","journal-title":"Ann Oncol"},{"key":"10.1378\/chest.07-1384_bib40","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1016\/S0169-5002(03)91727-2","article-title":"A randomised study of timing of thoracic irradiation in small cell lung cancer (SCLC): study 8","volume":"41(Suppl 2)","author":"James","year":"2003","journal-title":"Lung Cancer"},{"key":"10.1378\/chest.07-1384_bib41","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1056\/NEJM199901283400403","article-title":"Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide","volume":"340","author":"Turrisi","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.07-1384_bib42","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1002\/1097-0142(20001101)89:9<1953::AID-CNCR11>3.0.CO;2-6","article-title":"Similar outcome of elderly patients in intergroup trial 0096: cisplatin, etoposide, and thoracic radiotherapy administered once or twice daily in limited stage small cell lung carcinoma","volume":"89","author":"Yuen","year":"2000","journal-title":"Cancer"},{"key":"10.1378\/chest.07-1384_bib43","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.ijrobp.2004.01.055","article-title":"Long-term results of a phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer","volume":"59","author":"Schild","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1378\/chest.07-1384_bib44","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0360-3016(01)01819-3","article-title":"A quality-adjusted reanalysis of a phase III trial comparing once-daily thoracic radiation vs. twice-daily thoracic radiation in patients with limited-stage small-cell lung cancer","volume":"52","author":"Sloan","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1378\/chest.07-1384_bib45","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1200\/JCO.1999.17.9.2681","article-title":"Phase III comparison of twice-daily split-course irradiation vs once-daily irradiation for patients with limited stage small-cell lung carcinoma","volume":"17","author":"Bonner","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib46","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1200\/JCO.1999.17.7.2092","article-title":"Role of radiation therapy in the combined-modality treatment of patients with extensive disease small-cell lung cancer: a randomized study","volume":"17","author":"Jeremic","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib47","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1002\/1097-0142(19880915)62:6<1079::AID-CNCR2820620610>3.0.CO;2-S","article-title":"A randomized study of radiation treatment in small cell bronchial carcinoma treated with two types of four-drug chemotherapy regimens","volume":"62","author":"Nou","year":"1988","journal-title":"Cancer"},{"key":"10.1378\/chest.07-1384_bib48","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1378\/chest.104.3.726","article-title":"A randomized trial of delayed thoracic radiotherapy in complete responder patients with small-cell lung cancer: petites Cellules Group","volume":"104","author":"Lebeau","year":"1993","journal-title":"Chest"},{"key":"10.1378\/chest.07-1384_bib49","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0169-5002(91)90278-E","article-title":"Adjuvant thoracic radiotherapy in small cell lung cancer: ten-year follow-up of a randomized study","volume":"7","author":"Rosenthal","year":"1991","journal-title":"Lung Cancer"},{"key":"10.1378\/chest.07-1384_bib50","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0277-5379(87)90016-2","article-title":"Cyclic alternating polychemotherapy with or without upper and lower half-body irradiation in small cell anaplastic lung cancer: a randomized study","volume":"23","author":"Brincker","year":"1987","journal-title":"Eur J Cancer Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib51","first-page":"CD002805","article-title":"Prophylactic Cranial Irradiation Overview Collaborative Group.. Cranial irradiation for preventing brain metastases of small cell lung cancer in patients in complete remission","volume":"4","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1378\/chest.07-1384_bib52","first-page":"336","article-title":"Clinical study of prophylactic cranial irradiation for small-cell lung cancer","volume":"22","author":"Cao","year":"2000","journal-title":"Zhonghua Zhong Liu Za Zhi"},{"key":"10.1378\/chest.07-1384_bib53","doi-asserted-by":"crossref","first-page":"3248","DOI":"10.1200\/JCO.2004.11.089","article-title":"Positron emission tomography in limited-stage small-cell lung cancer: a prospective study","volume":"22","author":"Bradley","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib54","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1007\/s00259-004-1606-x","article-title":"Impact of (18F)FDG-PET on the primary staging of small-cell lung cancer","volume":"31","author":"Brink","year":"2004","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1378\/chest.07-1384_bib55","first-page":"1911","article-title":"Whole-body (18)F-FDG PET improves the management of patients with small cell lung cancer","volume":"44","author":"Kamel","year":"2003","journal-title":"J Nucl Med"},{"key":"10.1378\/chest.07-1384_bib56","first-page":"1257","article-title":"Whole-body 18F-2-deoxyglucose positron emission tomography in primary staging small cell lung cancer","volume":"22","author":"Shen","year":"2002","journal-title":"Anticancer Res"},{"key":"10.1378\/chest.07-1384_bib57","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/01.coc.0000054889.58718.6F","article-title":"Impact of positron emission tomography on the management of patients with small-cell lung cancer: preliminary experience","volume":"27","author":"Blum","year":"2004","journal-title":"Am J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib58","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s002590100474","article-title":"FDG-PET imaging for the staging and follow-up of small cell lung cancer","volume":"28","author":"Schumacher","year":"2001","journal-title":"Eur J Nucl Med"},{"key":"10.1378\/chest.07-1384_bib59","doi-asserted-by":"crossref","first-page":"320S","DOI":"10.1378\/chest.106.6_Supplement.320S","article-title":"A prospective randomized trial to determine the benefit of surgical resection of residual disease following response of small cell lung cancer to combination chemotherapy","volume":"106(6 suppl)","author":"Lad","year":"1994","journal-title":"Chest"},{"key":"10.1378\/chest.07-1384_bib60","first-page":"384","article-title":"Multimodality therapy of late stage lung cancer","volume":"17","author":"Liao","year":"1995","journal-title":"Zhonghua Zhong Liu Za Zhi"},{"key":"10.1378\/chest.07-1384_bib61","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ejcts.2004.04.012","article-title":"A retrospective comparative study of surgery followed by chemotherapy vs. non-surgical management in limited-disease small cell lung cancer","volume":"26","author":"Badzio","year":"2004","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1378\/chest.07-1384_bib62","doi-asserted-by":"crossref","first-page":"S316","DOI":"10.1016\/S0169-5002(05)81243-7","article-title":"The impact of primary pulmonary resection on local control and survival in limited disease (LD) small cell lung cancer (SCLC) patients (pts): a retrospective comparative study","volume":"49 (suppl 2)","author":"Badzio","year":"2005","journal-title":"Lung Cancer"},{"key":"10.1378\/chest.07-1384_bib63","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0022-5223(19)35322-X","article-title":"A prospective study of adjuvant surgical resection after chemotherapy for limited small cell lung cancer. a University of Toronto Lung Oncology Group study","volume":"97","author":"Shepherd","year":"1989","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1378\/chest.07-1384_bib64","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/BF02348565","article-title":"The role of surgical resection and the effects of neo-adjuvant therapy in the management of small cell lung cancer","volume":"24","author":"Namikawa","year":"1994","journal-title":"Surg Today"},{"key":"10.1378\/chest.07-1384_bib65","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1159\/000226977","article-title":"Long-term survivors in resected and nonresected small cell lung cancer","volume":"48","author":"Hara","year":"1991","journal-title":"Oncology"},{"key":"10.1378\/chest.07-1384_bib66","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/jso.2930470112","article-title":"Influence of surgical resection before and after chemotherapy on survival in small cell lung cancer","volume":"47","author":"Hara","year":"1991","journal-title":"J Surg Oncol"},{"key":"10.1378\/chest.07-1384_bib67","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1200\/JCO.1985.3.7.964","article-title":"Effect of initial resection of small-cell carcinoma of the lung: a review of Southwest Oncology Group Study 7628","volume":"3","author":"Friess","year":"1985","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib68","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1136\/thx.40.4.272","article-title":"Treatment policy of surgery in small cell carcinoma of the lung: retrospective analysis of a series of 874 consecutive patients","volume":"40","author":"Osterlind","year":"1985","journal-title":"Thorax"},{"key":"10.1378\/chest.07-1384_bib69","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.ejcts.2004.06.011","article-title":"Small cell lung cancer in Norway: should more patients have been offered surgical therapy?","volume":"26","author":"Rostad","year":"2004","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1378\/chest.07-1384_bib70","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1002\/1097-0142(19860915)58:6<1193::AID-CNCR2820580603>3.0.CO;2-J","article-title":"Long-term survival in limited-stage small cell lung carcinoma: experience in Rochester, New York from 1975 to 1981","volume":"58","author":"George","year":"1986","journal-title":"Cancer"},{"key":"10.1378\/chest.07-1384_bib71","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1200\/JCO.2001.19.6.1743","article-title":"Phase ii comparator study of oral vs intravenous topotecan in patients with chemosensitive small-cell lung cancer","volume":"19","author":"von Pawel","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib72","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1200\/JCO.1999.17.2.658","article-title":"Topotecan vs cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer","volume":"17","author":"von Pawel","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib73","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0959-8049(93)90176-G","article-title":"Testing the possible non-cross resistance of two equipotent combination chemotherapy regimens against small-cell lung cancer: a phase II study of the EORTC Lung Cancer Cooperative Group","volume":"29A","author":"Postmus","year":"1993","journal-title":"Eur J Cancer"},{"key":"10.1378\/chest.07-1384_bib74","first-page":"1173","article-title":"Comparison of 2 cisplatin and etoposide dosages in relapsing small cell lung cancer [in French]","volume":"79","author":"Trillet-Lenoir","year":"1992","journal-title":"Bull Cancer"},{"key":"10.1378\/chest.07-1384_bib75","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1002\/1097-0142(19900215)65:4<856::AID-CNCR2820650404>3.0.CO;2-6","article-title":"Comparison of etoposide and cisplatin with bis-chloro-ethylnitrosourea, thiotepa, vincristine, and cyclophosphamide for salvage treatment in small cell lung cancer: a Southwest Oncology Group Study","volume":"65","author":"O'Bryan","year":"1990","journal-title":"Cancer"},{"key":"10.1378\/chest.07-1384_bib76","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/bjc.1989.117","article-title":"Duration of chemotherapy in small cell lung cancer: a Cancer Research Campaign trial","volume":"59","author":"Spiro","year":"1989","journal-title":"Br J Cancer"},{"key":"10.1378\/chest.07-1384_bib77","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1093\/annonc\/mdf244","article-title":"A phase II randomised trial comparing the cisplatin-etoposide combination chemotherapy with or without carboplatin as second-line therapy for small-cell lung cancer","volume":"13","author":"Sculier","year":"2002","journal-title":"Ann Oncol"},{"key":"10.1378\/chest.07-1384_bib78","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1016\/S0169-5002(05)80291-0","article-title":"Survival benefit of oral topotecan plus supportive care vs supportive care alone in relapsed, resistant SCLC","volume":"49(Suppl 2)","author":"O'Brien","year":"2005","journal-title":"Lung Cancer"},{"key":"10.1378\/chest.07-1384_bib79","first-page":"583","article-title":"Randomized dose-response evaluation of etoposide in small cell carcinoma of the lung: a Southeastern Cancer Study Group Trial","volume":"70","author":"Wolff","year":"1986","journal-title":"Cancer Treat Rep"},{"key":"10.1378\/chest.07-1384_bib80","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1200\/JCO.1997.15.5.2090","volume":"15","author":"Ardizzoni","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib81","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.lungcan.2003.10.003","article-title":"Weekly administration of irinotecan (CPT-11) plus cisplatin for refractory or relapsed small cell lung cancer","volume":"44","author":"Ando","year":"2004","journal-title":"Lung Cancer"},{"key":"10.1378\/chest.07-1384_bib82","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1200\/JCO.2001.19.1.119","article-title":"Phase II study of paclitaxel, ifosfamide, and cisplatin as second-line treatment in relapsed small-cell lung cancer","volume":"19","author":"Kosmas","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib83","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1023\/A:1008322932251","article-title":"Paclitaxel in combination with carboplatin as salvage treatment in refractory small-cell lung cancer (SCLC): a multicenter phase II study","volume":"12","author":"Kakolyris","year":"2001","journal-title":"Ann Oncol"},{"key":"10.1378\/chest.07-1384_bib84","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1097\/00000421-200002000-00019","article-title":"Phase II study of doxorubicin and paclitaxel as second-line chemotherapy of small-cell lung cancer: a Hoosier Oncology Group Trial","volume":"23","author":"Sonpavde","year":"2000","journal-title":"Am J Clin Oncol"},{"key":"10.1378\/chest.07-1384_bib85","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1378\/chest.07-1385","article-title":"Management of small cell lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition)","volume":"132","author":"Simon","year":"2007","journal-title":"Chest"},{"key":"10.1378\/chest.07-1384_bib86","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1373\/49.1.1","article-title":"Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative","volume":"49","author":"Bossuyt","year":"2003","journal-title":"Clin Chem"},{"key":"10.1378\/chest.07-1384_bib87","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1373\/49.1.7","article-title":"The STARD statement for reporting of studies of diagnostic accuracy: explanation and elaboration","volume":"49","author":"Bossuyt","year":"2003","journal-title":"Clin Chem"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215355288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215355288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T07:04:13Z","timestamp":1757919853000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215355288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":83,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S0012369215355288"],"URL":"https:\/\/doi.org\/10.1378\/chest.07-1384","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evidence for Management of Small Cell Lung Cancer","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.07-1384","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}