{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T14:52:45Z","timestamp":1769525565757,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[1993,1]]},"DOI":"10.1378\/chest.103.1.111","type":"journal-article","created":{"date-parts":[[2007,11,7]],"date-time":"2007-11-07T13:28:23Z","timestamp":1194442103000},"page":"111-116","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Pulmonary Function and Hypoxic Ventilatory Response in Subjects Susceptible to High-Altitude Pulmonary Edema"],"prefix":"10.1016","volume":"103","author":[{"given":"Mark A.","family":"Selland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Stelzner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Troy","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Mazzeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert E.","family":"McCullough","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John T.","family":"Reeves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1378\/chest.103.1.111_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1580\/0953-9859-1.1.3","article-title":"High altitude pulmonary edema","volume":"1","author":"Hackett","year":"1990","journal-title":"J Wilderness Med"},{"key":"10.1378\/chest.103.1.111_bib2","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0002-8703(82)90536-1","article-title":"Mechanisms and consequences of pulmonary edema: cardiac lung, shock lung, and principles of ventilatory therapy in adult respiratory distress syndrome","volume":"103","author":"Ayres","year":"1982","journal-title":"Am Heart J"},{"key":"10.1378\/chest.103.1.111_bib3","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1378\/chest.72.3.350","article-title":"Clinical significance of pulmonary function tests\u2014pulmonary function after uncomplicated myocardial infarction","volume":"72","author":"Hales","year":"1977","journal-title":"Chest"},{"key":"10.1378\/chest.103.1.111_bib4","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0002-9343(73)90161-7","article-title":"Pulmonary function with acute loss of excess lung water by hemodialysis in patients with chronic uremia","volume":"55","author":"Zidulka","year":"1973","journal-title":"Am J Med"},{"key":"10.1378\/chest.103.1.111_bib5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1152\/jappl.1979.46.1.41","article-title":"Accentuated hypoxemia at high altitude in subjects susceptible to high-altitude pulmonary edema","volume":"46","author":"Hyers","year":"1979","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib6","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1152\/jappl.1988.64.3.1268","article-title":"Abnormal control of ventilation in high-altitude pulmonary edema","volume":"64","author":"Hackett","year":"1988","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib7","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1152\/jappl.1989.66.3.1152","article-title":"Blunted hypoxic ventilatory drive in subjects susceptible to high-altitude pulmonary edema","volume":"66","author":"Matsuzawa","year":"1989","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib8","first-page":"1032","article-title":"Pulmonary gas exchange in acute mountain sickness","volume":"47","author":"Sutton","year":"1976","journal-title":"Aviat Space Environ Med"},{"key":"10.1378\/chest.103.1.111_bib9","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1152\/jappl.1986.60.4.1407","article-title":"Low acute hypoxic ventilatory response and hypoxic depression in acute altitude sickness","volume":"60","author":"Moore","year":"1986","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib10","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1172\/JCI106322","article-title":"Hypoxic ventilatory drive in normal man","volume":"49","author":"Weil","year":"1970","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.103.1.111_bib11","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1164\/ajrccm\/136.5.1285","article-title":"Standardization of spirometry\u2013 1987 update","volume":"136","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.103.1.111_bib12","first-page":"1063","article-title":"Procedures for the measurement of acute mountain sickness","volume":"54","author":"Sampson","year":"1983","journal-title":"Aviat Space Environ Med"},{"key":"10.1378\/chest.103.1.111_bib13","first-page":"950","article-title":"Dexamethasone for prevention and treatment of acute mountain sickness","volume":"59","author":"Hackett","year":"1988","journal-title":"Aviat Space Environ Med"},{"key":"10.1378\/chest.103.1.111_bib14","series-title":"Hypoxia and mountain medicine","first-page":"327","year":"1992"},{"key":"10.1378\/chest.103.1.111_bib15","first-page":"1055","article-title":"Diagnosis of airflow obstruction at high altitude","volume":"117","author":"Kryger","year":"1978","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.103.1.111_bib16","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1152\/jappl.1986.60.6.1894","article-title":"Influence of body size and gender on control of ventilation","volume":"60","author":"Aitken","year":"1986","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib17","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1164\/arrd.1969.100.3.334","article-title":"Pulmonary edema of high altitude, II: clinical, aerohemodynamic, and biochemical studies in a group with history of pulmonary edema of high altitude","volume":"100","author":"Viswanathan","year":"1969","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.103.1.111_bib18","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF00952546","article-title":"Chemoreceptor sensitivity and maladaptation to high altitude in man","volume":"51","author":"Mathew","year":"1983","journal-title":"Eur J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib19","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1161\/01.CIR.44.5.759","article-title":"Abnormal circulatory responses to high altitude in subjects with a previous history of high-altitude pulmonary edema","volume":"44","author":"Hultgren","year":"1971","journal-title":"Circulation"},{"key":"10.1378\/chest.103.1.111_bib20","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1152\/jappl.1979.47.4.670","article-title":"Evidence for increased intrathoracic fluid volume in man at high altitude","volume":"47","author":"Jaeger","year":"1979","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib21","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1152\/jappl.1979.46.1.41","article-title":"Accentuated hypoxemia at high altitude in subjects susceptible to high-altitude pulmonary edema","volume":"46","author":"Hyers","year":"1979","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1001\/jama.1986.03380010067027","article-title":"High-altitude pulmonary edema: characteristics of lung lavage","volume":"256","author":"Schoene","year":"1986","journal-title":"JAMA"},{"key":"10.1378\/chest.103.1.111_bib23","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1152\/jappl.1979.46.4.792","article-title":"Small airways impairment during progressive hemorrhage and early shock in dogs","volume":"46","author":"Delaunois","year":"1979","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib24","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1159\/000194501","article-title":"Fluid retention and relative hypoventilation in acute mountain sickness","volume":"43","author":"Hackett","year":"1982","journal-title":"Respiration"},{"key":"10.1378\/chest.103.1.111_bib25","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1164\/arrd.1972.106.1.100","article-title":"Recurrent respiratory failure associated with the absence of ventilatory response to hypercapnia and hypoxemia","volume":"106","author":"Kafer","year":"1972","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.103.1.111_bib26","first-page":"419","article-title":"Ventilation response to hypoxia and acute mountain sickness","volume":"43","author":"King","year":"1972","journal-title":"Aerospace Med"},{"key":"10.1378\/chest.103.1.111_bib27","first-page":"869","article-title":"Recurrent high altitude pulmonary edema with blunted chemosensitivity","volume":"111","author":"Lakshminarayan","year":"1975","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.103.1.111_bib28","series-title":"High altitude physiology and medicine","first-page":"28","article-title":"Chemoreflexive ventilatory response at sea level in subjects with past history of good acclimatization and severe acute mountain sickness. In:","author":"Hu","year":"1982"},{"key":"10.1378\/chest.103.1.111_bib29","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1152\/jappl.1986.61.2.500","article-title":"Control of ventilation in extreme-altitude climbers","volume":"61","author":"Masuyama","year":"1986","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.103.1.111_bib30","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1152\/jappl.1975.38.6.1095","article-title":"Normal values for hypoxic and hypercapnic ventilatory drives in man","volume":"38","author":"Hirshman","year":"1975","journal-title":"J Appl Physiol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216383064?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216383064?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T07:42:29Z","timestamp":1757922149000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369216383064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1993,1]]}},"alternative-id":["S0012369216383064"],"URL":"https:\/\/doi.org\/10.1378\/chest.103.1.111","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[1993,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pulmonary Function and Hypoxic Ventilatory Response in Subjects Susceptible to High-Altitude Pulmonary Edema","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.103.1.111","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1993 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}