{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T08:23:48Z","timestamp":1785572628758,"version":"3.56.0"},"reference-count":8,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1994,4,1]],"date-time":"1994-04-01T00:00:00Z","timestamp":765158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[1994,4]]},"DOI":"10.1378\/chest.105.4.1263","type":"journal-article","created":{"date-parts":[[2007,11,7]],"date-time":"2007-11-07T18:28:23Z","timestamp":1194460103000},"page":"1263-1264","source":"Crossref","is-referenced-by-count":15,"title":["Successful Treatment of ARDS With Two Doses of Synthetic Surfactant"],"prefix":"10.1016","volume":"105","author":[{"given":"Markku","family":"Heikinheimo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markku","family":"Hynynen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Rautiainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sture","family":"Andersson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikko","family":"Hallman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinikka","family":"Kukkonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1378\/chest.105.4.1263_bib1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0140-6736(67)90168-7","article-title":"Acute respiratory distress in adults","volume":"2","author":"Ashbaugh","year":"1967","journal-title":"Lancet"},{"key":"10.1378\/chest.105.4.1263_bib2","first-page":"531","article-title":"Characteristics of pulmonary surfactant in adult respiratory distress syndrome associated with trauma and shock","volume":"115","author":"Petty","year":"1977","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.105.4.1263_bib3","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1056\/NEJM198609253151301","article-title":"Prophylactic treatment of very premature infants with human surfactant","volume":"315","author":"Merritt","year":"1986","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.105.4.1263_bib4","series-title":"Surfactant replacement therapy","first-page":"212","article-title":"Surfactant replacement in acute respiratory failure: animal studies and first clinical trials","author":"Lachmann","year":"1988"},{"issue":"suppl 3","key":"10.1378\/chest.105.4.1263_bib5","first-page":"109","article-title":"The adult respiratory distress syndrome: first trial with surfactant replacement","volume":"2","author":"Richman","year":"1989","journal-title":"Eur Respir J"},{"issue":"suppl","key":"10.1378\/chest.105.4.1263_bib6","first-page":"37","article-title":"The phospholipids in the airway specimens are similar to phospholipids in bronchoalveolar lavage","volume":"142","author":"Hallman","year":"1985","journal-title":"Eur J Respir Dis"},{"key":"10.1378\/chest.105.4.1263_bib7","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1172\/JCI110662","article-title":"Evidence of lung surfactant abnormality in respiratory failure","volume":"70","author":"Hallman","year":"1982","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.105.4.1263_bib8","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1016\/S0022-3476(05)81231-4","article-title":"Elastase activity and surfactant protein concentration in tracheal aspirates from neonates receiving synthetic surfactant","volume":"120","author":"Gerdes","year":"1992","journal-title":"J Pediatr"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216577009?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216577009?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T05:55:38Z","timestamp":1546494938000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369216577009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,4]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1994,4]]}},"alternative-id":["S0012369216577009"],"URL":"https:\/\/doi.org\/10.1378\/chest.105.4.1263","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[1994,4]]}}}