{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T04:15:50Z","timestamp":1781842550822,"version":"3.54.5"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1378\/chest.11-0180","type":"journal-article","created":{"date-parts":[[2011,7,21]],"date-time":"2011-07-21T21:10:23Z","timestamp":1311282623000},"page":"461-468","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":75,"title":["Clinical Efficacy and Safety of Budesonide-Formoterol in Non-Cystic Fibrosis Bronchiectasis"],"prefix":"10.1016","volume":"141","author":[{"given":"Miguel \u00c1ngel","family":"Mart\u00ednez-Garc\u00eda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan J.","family":"Soler-Catalu\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Catal\u00e1n-Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Rom\u00e1n-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel Perpi\u00f1\u00e1","family":"Tordera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1378\/chest.11-0180_bib1","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1378\/chest.08-0776","article-title":"Bronchiectasis","volume":"134","author":"O'Donnell","year":"2008","journal-title":"Chest"},{"issue":"2","key":"10.1378\/chest.11-0180_bib2","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1378\/chest.128.2.739","article-title":"Quality-of-life determinants in patients with clinically stable bronchiectasis","volume":"128","author":"Mart\u00ednez-Garc\u00eda","year":"2005","journal-title":"Chest"},{"issue":"7629","key":"10.1378\/chest.11-0180_bib3","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1136\/bmj.39384.657118.80","article-title":"Treatment of bronchiectasis in adults","volume":"335","author":"ten Hacken","year":"2007","journal-title":"BMJ"},{"issue":"11","key":"10.1378\/chest.11-0180_bib4","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1157\/13128330","article-title":"Diagnosis and treatement of bronchiectasis. Spanish Society of Pneumology and Thoracic Surgery [in Spanish]","volume":"44","author":"Vendrell","year":"2008","journal-title":"Arch Bronconeumol"},{"issue":"2","key":"10.1378\/chest.11-0180_bib5","first-page":"129","article-title":"Budesonide turbuhaler delivered once daily improves health-related quality of life in adult patients with non-steroid-dependent asthma","volume":"24","author":"Banov","year":"2003","journal-title":"Allergy Asthma Proc"},{"issue":"8","key":"10.1378\/chest.11-0180_bib6","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1056\/NEJMoa063070","article-title":"Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease","volume":"356","author":"Calverley","year":"2007","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1378\/chest.11-0180_bib7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1513\/pats.200402-012MS","article-title":"Clinical effects of inhaled corticosteroids in chronic obstructive pulmonary disease","volume":"1","author":"Jones","year":"2004","journal-title":"Proc Am Thorac Soc"},{"issue":"2","key":"10.1378\/chest.11-0180_bib8","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0954-6111(06)80227-1","article-title":"Inhaled steroids in patients with bronchiectasis","volume":"86","author":"Elborn","year":"1992","journal-title":"Respir Med"},{"issue":"3","key":"10.1378\/chest.11-0180_bib9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1136\/thx.2002.003236","article-title":"Inhaled fluticasone in bronchiectasis: a 12 month study","volume":"60","author":"Tsang","year":"2005","journal-title":"Thorax"},{"issue":"9","key":"10.1378\/chest.11-0180_bib10","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/j.rmed.2005.12.002","article-title":"Inhaled steroids improve quality of life in patients with steady-state bronchiectasis","volume":"100","author":"Mart\u00ednez-Garc\u00eda","year":"2006","journal-title":"Respir Med"},{"issue":"3","key":"10.1378\/chest.11-0180_bib11","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1164\/ajrccm.158.3.9710090","article-title":"Inhaled fluticasone reduces sputum inflammatory indices in severe bronchiectasis","volume":"158","author":"Tsang","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1378\/chest.11-0180_bib12","first-page":"CD005535","article-title":"Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children","volume":"5","author":"Ducharme","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"10.1378\/chest.11-0180_bib13","first-page":"CD006826","article-title":"Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease","author":"Nannini","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1378\/chest.11-0180_bib14","author":"Global Initiative for Asthma"},{"issue":"5","key":"10.1378\/chest.11-0180_bib15","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1093\/clinchem\/32.5.850","article-title":"Evaluation of a cystic fibrosis screening system incorporating a miniature sweat stimulator and disposable chloride sensor","volume":"32","author":"Warwick","year":"1986","journal-title":"Clin Chem"},{"issue":"3","key":"10.1378\/chest.11-0180_bib16","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/00004728-198206000-00001","article-title":"Computed tomography of bronchiectasis","volume":"6","author":"Naidich","year":"1982","journal-title":"J Comput Assist Tomogr"},{"issue":"3","key":"10.1378\/chest.11-0180_bib17","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1148\/radiology.179.3.2027992","article-title":"Cystic fibrosis: scoring system with thin-section CT","volume":"179","author":"Bhalla","year":"1991","journal-title":"Radiology"},{"issue":"3","key":"10.1378\/chest.11-0180_bib18","first-page":"217","article-title":"Spirometric reference values from a Mediterranean population","volume":"22","author":"Roca","year":"1986","journal-title":"Bull Eur Physiopathol Respir"},{"issue":"3","key":"10.1378\/chest.11-0180_bib19","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1157\/13071580","article-title":"Internal consistency and validity of the Spanish version of St. George's respiratory questionnaire for use in patients with clinically stable bronchiectasis in Spanish]","volume":"41","author":"Mart\u00ednez-Garc\u00eda","year":"2005","journal-title":"Arch Bronconeumol"},{"issue":"suppl B","key":"10.1378\/chest.11-0180_bib20","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0954-6111(06)80166-6","article-title":"The St George's Respiratory Questionnaire","volume":"85","author":"Jones","year":"1991","journal-title":"Respir Med"},{"issue":"6","key":"10.1378\/chest.11-0180_bib21","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1378\/chest.85.6.751","article-title":"The measurement of dyspnea. Contents, interobserver agreement, and physiologic correlates of two new clinical indexes","volume":"85","author":"Mahler","year":"1984","journal-title":"Chest"},{"issue":"2","key":"10.1378\/chest.11-0180_bib22","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1183\/09031936.00069007","article-title":"Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms","volume":"31","author":"Fuschillo","year":"2008","journal-title":"Eur Respir J"},{"issue":"1","key":"10.1378\/chest.11-0180_bib23","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1172\/JCI118084","article-title":"Protective effects of a glucocorticoid on downregulation of pulmonary beta 2-adrenergic receptors in vivo","volume":"96","author":"Mak","year":"1995","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1378\/chest.11-0180_bib24","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1165\/ajrcmb.23.1.3985","article-title":"Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells","volume":"23","author":"Pang","year":"2000","journal-title":"Am J Respir Cell Mol Biol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369212600853?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369212600853?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T06:27:18Z","timestamp":1757917638000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369212600853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0012369212600853"],"URL":"https:\/\/doi.org\/10.1378\/chest.11-0180","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical Efficacy and Safety of Budesonide-Formoterol in Non-Cystic Fibrosis Bronchiectasis","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.11-0180","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}