{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:34:33Z","timestamp":1791196473007,"version":"4.1.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1378\/chest.11-1387","type":"journal-article","created":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T20:18:19Z","timestamp":1338581899000},"page":"185-195","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"title":["Demographics and Outcomes of Patients Diagnosed With Pulmonary Hypertension With Pulmonary Capillary Wedge Pressures 16 to 18 mm Hg"],"prefix":"10.1016","volume":"143","author":[{"given":"Adaani E.","family":"Frost","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harrison W.","family":"Farber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn J.","family":"Barst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave P.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Gregory","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"McGoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1 Suppl","key":"10.1378\/chest.11-1387_bib1","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/j.jacc.2009.04.011","article-title":"Diagnosis and assessment of pulmonary arterial hypertension","volume":"54","author":"Badesch","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"16","key":"10.1378\/chest.11-1387_bib2","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1161\/CIRCULATIONAHA.109.192230","volume":"119","author":"McLaughlin","year":"2009","journal-title":"Circulation"},{"issue":"8","key":"10.1378\/chest.11-1387_bib3","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0025-6196(11)60769-6","article-title":"Design of the REVEAL registry for US patients with pulmonary arterial hypertension","volume":"83","author":"McGoon","year":"2008","journal-title":"Mayo Clin Proc"},{"issue":"1","key":"10.1378\/chest.11-1387_bib4","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1378\/chest.10-0075","article-title":"The changing picture of pulmonary arterial hypertension (PAH) patients in the United States: how the REVEAL registry differs from historic and non-US contemporary registries","volume":"139","author":"Frost","year":"2011","journal-title":"Chest"},{"issue":"1 suppl","key":"10.1378\/chest.11-1387_bib5","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1016\/j.jacc.2009.04.012","article-title":"Updated clinical classification of pulmonary hypertension","volume":"54","author":"Simonneau","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"10.1378\/chest.11-1387_bib6","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1136\/thorax.55.11.934","article-title":"Pulmonary arterial hypertension in patients with sleep apnoea syndrome","volume":"55","author":"Bady","year":"2000","journal-title":"Thorax"},{"issue":"4","key":"10.1378\/chest.11-1387_bib7","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1183\/09031936.96.09040787","article-title":"Pulmonary hypertension in the obstructive sleep apnoea syndrome: prevalence, causes and therapeutic consequences","volume":"9","author":"Kessler","year":"1996","journal-title":"Eur Respir J"},{"issue":"1","key":"10.1378\/chest.11-1387_bib8","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1378\/chest.06-1571","article-title":"Unexplained pulmonary hypertension in elderly patients","volume":"131","author":"Shapiro","year":"2007","journal-title":"Chest"},{"issue":"18","key":"10.1378\/chest.11-1387_bib9","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1093\/eurheartj\/ehq245","article-title":"Determinants and prognostic value of pulmonary arterial pressure in patients with chronic heart failure","volume":"31","author":"Damy","year":"2010","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1378\/chest.11-1387_bib10","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0002-8703(97)70105-4","article-title":"A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST)","volume":"134","author":"Califf","year":"1997","journal-title":"Am Heart J"},{"issue":"2","key":"10.1378\/chest.11-1387_bib11","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1378\/chest.09-1140","article-title":"Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry","volume":"137","author":"Badesch","year":"2010","journal-title":"Chest"},{"issue":"12","key":"10.1378\/chest.11-1387_bib12","doi-asserted-by":"crossref","first-page":"5S","DOI":"10.1016\/j.jacc.2004.02.037","article-title":"Clinical classification of pulmonary hypertension","volume":"43","author":"Simonneau","year":"2004","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1378\/chest.11-1387_bib13","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/pds.1357","article-title":"Immortal time bias in observational studies of drug effects","volume":"16","author":"Suissa","year":"2007","journal-title":"Pharmacoepidemiol Drug Saf"},{"issue":"4","key":"10.1378\/chest.11-1387_bib14","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1093\/biomet\/74.4.883","article-title":"A note on the product-limit estimator under right censoring and left truncation","volume":"74","author":"Tsai","year":"1987","journal-title":"Biometrika"},{"issue":"9","key":"10.1378\/chest.11-1387_bib15","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1002\/(SICI)1097-0258(19970515)16:9<1041::AID-SIM506>3.0.CO;2-F","article-title":"Survival analysis in observational studies","volume":"16","author":"Bull","year":"1997","journal-title":"Stat Med"},{"issue":"9431","key":"10.1378\/chest.11-1387_bib16","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0140-6736(04)16723-8","article-title":"Long-term effects of darusentan on left-ventricular remodelling and clinical outcomes in the EndothelinA Receptor Antagonist Trial in Heart Failure (EARTH): randomised, double-blind, placebo-controlled trial","volume":"364","author":"Anand","year":"2004","journal-title":"Lancet"},{"issue":"1","key":"10.1378\/chest.11-1387_bib17","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.cardfail.2004.05.006","article-title":"Clinical effects of endothelin receptor antagonism with bosentan in patients with severe chronic heart failure: results of a pilot study","volume":"11","author":"Packer","year":"2005","journal-title":"J Card Fail"},{"issue":"3","key":"10.1378\/chest.11-1387_bib18","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1054\/jcaf.2002.126486","article-title":"Recent heart failure trials of neurohormonal modulation (OVERTURE and ENABLE): approaching the asymptote of efficacy?","volume":"8","author":"Teerlink","year":"2002","journal-title":"J Card Fail"},{"issue":"4","key":"10.1378\/chest.11-1387_bib19","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000107791","article-title":"Clinical and hemodynamic effects of bosentan dose optimization in symptomatic heart failure patients with severe systolic dysfunction, associated with secondary pulmonary hypertension\u2014a multi-center randomized study","volume":"109","author":"Kaluski","year":"2008","journal-title":"Cardiology"},{"issue":"1","key":"10.1378\/chest.11-1387_bib20","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1378\/chest.08-2008","article-title":"Association of the metabolic syndrome with pulmonary venous hypertension","volume":"136","author":"Robbins","year":"2009","journal-title":"Chest"},{"issue":"8","key":"10.1378\/chest.11-1387_bib21","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.amjcard.2006.11.052","article-title":"Prognostic importance of pulmonary hypertension in patients with heart failure","volume":"99","author":"Kjaergaard","year":"2007","journal-title":"Am J Cardiol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213600306?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213600306?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T22:56:38Z","timestamp":1762124198000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369213600306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0012369213600306"],"URL":"https:\/\/doi.org\/10.1378\/chest.11-1387","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Demographics and Outcomes of Patients Diagnosed With Pulmonary Hypertension With Pulmonary Capillary Wedge Pressures 16 to 18 mm Hg","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.11-1387","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}