{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:38:36Z","timestamp":1790267916108,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":1011,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1378\/chest.12-0228","type":"journal-article","created":{"date-parts":[[2013,3,5]],"date-time":"2013-03-05T07:25:08Z","timestamp":1362468308000},"page":"678-686","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":184,"title":["A Novel Extracorporeal CO2 Removal System"],"prefix":"10.1016","volume":"143","author":[{"given":"Nausherwan K.","family":"Burki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj Kumar","family":"Mani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix J.F.","family":"Herth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Teschler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Bonin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinrich","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winfried J.","family":"Randerath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Stieglitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Hagmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Priegnitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Pfeifer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan H.","family":"Blaas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Putensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Theuerkauf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Quintel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onnen","family":"Moerer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1378\/chest.12-0228_bib1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.7326\/0003-4819-155-3-201108020-00008","article-title":"Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society","volume":"155","author":"Qaseem","year":"2011","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1378\/chest.12-0228_bib2","first-page":"719","article-title":"Further observations on the course and prognosis of chronic obstructive lung disease","volume":"111","author":"Diener","year":"1975","journal-title":"Am Rev Respir Dis"},{"issue":"2","key":"10.1378\/chest.12-0228_bib3","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1136\/thx.42.2.105","article-title":"Twelve year clinical study of patients with hypoxic cor pulmonale given long term domiciliary oxygen therapy","volume":"42","author":"Cooper","year":"1987","journal-title":"Thorax"},{"issue":"4 pt 1","key":"10.1378\/chest.12-0228_bib4","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1164\/ajrccm.154.4.8887592","article-title":"Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments)","volume":"154","author":"Connors","year":"1996","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1378\/chest.12-0228_bib5","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1183\/09031936.00043710","article-title":"Case fatality of COPD exacerbations: a meta-analysis and statistical modelling approach","volume":"37","author":"Hoogendoorn","year":"2011","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1378\/chest.12-0228_bib6","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1164\/rccm.201106-1094OC","article-title":"Outcomes of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the United States, 1998\u20132008","volume":"185","author":"Chandra","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1378\/chest.12-0228_bib7","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1378\/chest.117.1.169","article-title":"Hypercapnic respiratory failure in COPD patients: response to therapy","volume":"117","author":"Hoo","year":"2000","journal-title":"Chest"},{"issue":"1","key":"10.1378\/chest.12-0228_bib8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1378\/chest.129.1.133","article-title":"Prolonged invasive ventilation following acute ventilatory failure in COPD: weaning results, survival, and the role of noninvasive ventilation","volume":"129","author":"Quinnell","year":"2006","journal-title":"Chest"},{"issue":"2","key":"10.1378\/chest.12-0228_bib9","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1378\/chest.95.2.398","article-title":"Determinants of weaning and survival among patients with COPD who require mechanical ventilation for acute respiratory failure","volume":"95","author":"Menzies","year":"1989","journal-title":"Chest"},{"issue":"12","key":"10.1378\/chest.12-0228_bib10","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1136\/thx.2004.024307","article-title":"Readmission rates and life threatening events in COPD survivors treated with non-invasive ventilation for acute hypercapnic respiratory failure","volume":"59","author":"Chu","year":"2004","journal-title":"Thorax"},{"issue":"8189","key":"10.1378\/chest.12-0228_bib11","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S0140-6736(80)90237-8","article-title":"Treatment of acute respiratory failure with low-frequency positive-pressure ventilation and extracorporeal removal of CO2","volume":"2","author":"Gattinoni","year":"1980","journal-title":"Lancet"},{"issue":"7","key":"10.1378\/chest.12-0228_bib12","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1001\/jama.1986.03380070087025","article-title":"Low-frequency positive-pressure ventilation with extracorporeal CO2 removal in severe acute respiratory failure","volume":"256","author":"Gattinoni","year":"1986","journal-title":"JAMA"},{"issue":"6","key":"10.1378\/chest.12-0228_bib13","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1097\/CCM.0b013e31820eda45","article-title":"Respiratory dialysis: reduction in dependence on mechanical ventilation by venovenous extracorporeal CO2 removal","volume":"39","author":"Batchinsky","year":"2011","journal-title":"Crit Care Med"},{"issue":"2","key":"10.1378\/chest.12-0228_bib14","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1183\/09031936.05.00085304","article-title":"A chart of failure risk for noninvasive ventilation in patients with COPD exacerbation","volume":"25","author":"Confalonieri","year":"2005","journal-title":"Eur Respir J"},{"issue":"4","key":"10.1378\/chest.12-0228_bib15","first-page":"1040","article-title":"Dyspnea: mechanisms, evaluation and treatment","volume":"138","author":"Burki","year":"1988","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.12-0228_bib16","author":"Global Initiative for Chronic Obstructive Lung Disease"},{"issue":"9","key":"10.1378\/chest.12-0228_bib17","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.7863\/jum.2009.28.9.1239","article-title":"Video analysis of accidental arterial cannulation with dynamic ultrasound guidance for central venous access","volume":"28","author":"Blaivas","year":"2009","journal-title":"J Ultrasound Med"},{"issue":"6","key":"10.1378\/chest.12-0228_bib18","first-page":"1581","article-title":"Is extracorporeal CO2 removal an option in the treatment of adult respiratory distress syndrome?","volume":"64","author":"Deslauriers","year":"1997","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"10.1378\/chest.12-0228_bib19","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/01.MAT.0000151922.67540.E9","article-title":"Extracorporeal life support registry report 2004","volume":"51","author":"Conrad","year":"2005","journal-title":"ASAIO J"},{"issue":"2 pt 1","key":"10.1378\/chest.12-0228_bib20","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1164\/ajrccm.149.2.8306022","article-title":"Randomized clinical trial of pressure-controlled inverse ratio ventilation and extracorporeal CO2 removal for adult respiratory distress syndrome","volume":"149","author":"Morris","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1378\/chest.12-0228_bib21","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1097\/01.CCM.0000215111.85483.BD","article-title":"A new pumpless extracorporeal interventional lung assist in critical hypoxemia\/hypercapnia","volume":"34","author":"Bein","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.12-0228_bib22","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1159\/000313758","article-title":"Extracorporeal CO2 removal","volume":"165","author":"Terragni","year":"2010","journal-title":"Contrib Nephrol"},{"issue":"4","key":"10.1378\/chest.12-0228_bib23","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1097\/ALN.0b013e3181b764d2","article-title":"Tidal volume lower than 6 ml\/kg enhances lung protection: role of extracorporeal carbon dioxide removal","volume":"111","author":"Terragni","year":"2009","journal-title":"Anesthesiology"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213601476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213601476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T06:35:45Z","timestamp":1757918145000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369213601476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S0012369213601476"],"URL":"https:\/\/doi.org\/10.1378\/chest.12-0228","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Novel Extracorporeal CO2 Removal System","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.12-0228","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The American College of Chest Physicians. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}