{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:26:53Z","timestamp":1791188813214,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1378\/chest.12-0424","type":"journal-article","created":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T20:18:19Z","timestamp":1338581899000},"page":"30-36","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":76,"title":["Neurally Adjusted Ventilatory Assist vs Pressure Support Ventilation for Noninvasive Ventilation During Acute Respiratory Failure"],"prefix":"10.1016","volume":"143","author":[{"given":"Pierre-Marie","family":"Bertrand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Futier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yannael","family":"Coisel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Matecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Jaber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Michel","family":"Constantin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1378\/chest.12-0424_bib1","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1097\/01.CCM.0000284587.36541.7F","article-title":"Noninvasive ventilation in acute respiratory failure","volume":"35","author":"Hill","year":"2007","journal-title":"Crit Care Med"},{"issue":"9685","key":"10.1378\/chest.12-0424_bib2","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0140-6736(09)60496-7","article-title":"Non-invasive ventilation in acute respiratory failure","volume":"374","author":"Nava","year":"2009","journal-title":"Lancet"},{"issue":"12","key":"10.1378\/chest.12-0424_bib3","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1164\/rccm.200301-072OC","article-title":"Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial","volume":"168","author":"Ferrer","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"10.1378\/chest.12-0424_bib4","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1164\/rccm.200402-226OC","article-title":"Physiologic effects of noninvasive ventilation during acute lung injury","volume":"172","author":"L'Her","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1378\/chest.12-0424_bib5","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1164\/ajrccm.163.5.2005125","article-title":"Patient-ventilator interaction","volume":"163","author":"Tobin","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1378\/chest.12-0424_bib6","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1007\/s00134-009-1416-5","article-title":"Patient-ventilator asynchrony during non-invasive ventilation for acute respiratory failure: a multicenter study","volume":"35","author":"Vignaux","year":"2009","journal-title":"Intensive Care Med"},{"issue":"12","key":"10.1378\/chest.12-0424_bib7","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1038\/71012","article-title":"Neural control of mechanical ventilation in respiratory failure","volume":"5","author":"Sinderby","year":"1999","journal-title":"Nat Med"},{"issue":"3","key":"10.1378\/chest.12-0424_bib8","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1378\/chest.06-1909","article-title":"Inspiratory muscle unloading by neurally adjusted ventilatory assist during maximal inspiratory efforts in healthy subjects","volume":"131","author":"Sinderby","year":"2007","journal-title":"Chest"},{"issue":"2","key":"10.1378\/chest.12-0424_bib9","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00134-010-2052-9","article-title":"Neurally adjusted ventilatory assist improves patient-ventilator interaction","volume":"37","author":"Piquilloud","year":"2011","journal-title":"Intensive Care Med"},{"issue":"2","key":"10.1378\/chest.12-0424_bib10","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1097\/CCM.0b013e3181cb0d7b","article-title":"Patient-ventilator interaction during pressure support ventilation and neurally adjusted ventilatory assist","volume":"38","author":"Spahija","year":"2010","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.12-0424_bib11","doi-asserted-by":"crossref","first-page":"c332","DOI":"10.1136\/bmj.c332","article-title":"CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials","volume":"340","author":"Schulz","year":"2010","journal-title":"BMJ"},{"issue":"4","key":"10.1378\/chest.12-0424_bib12","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1152\/jappl.1997.82.4.1370","article-title":"Enhancement of signal quality in esophageal recordings of diaphragm EMG","volume":"82","author":"Sinderby","year":"1997","journal-title":"J Appl Physiol"},{"issue":"10","key":"10.1378\/chest.12-0424_bib13","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1007\/s00134-009-1587-0","article-title":"Evaluation of the catheter positioning for neurally adjusted ventilatory assist","volume":"35","author":"Barwing","year":"2009","journal-title":"Intensive Care Med"},{"issue":"12","key":"10.1378\/chest.12-0424_bib14","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1007\/s00134-010-1994-2","article-title":"Performance of noninvasive ventilation algorithms on ICU ventilators during pressure support: a clinical study","volume":"36","author":"Vignaux","year":"2010","journal-title":"Intensive Care Med"},{"issue":"11","key":"10.1378\/chest.12-0424_bib15","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1007\/s00134-008-1208-3","article-title":"Physiologic response to varying levels of pressure support and neurally adjusted ventilatory assist in patients with acute respiratory failure","volume":"34","author":"Colombo","year":"2008","journal-title":"Intensive Care Med"},{"issue":"9","key":"10.1378\/chest.12-0424_bib16","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1097\/CCM.0b013e3181eb3c51","article-title":"Neurally adjusted ventilatory assist in patients recovering spontaneous breathing after acute respiratory distress syndrome: physiological evaluation","volume":"38","author":"Terzi","year":"2010","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1378\/chest.12-0424_bib17","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1097\/ALN.0b013e31821811ba","article-title":"Noninvasive ventilation and alveolar recruitment maneuver improve respiratory function during and after intubation of morbidly obese patients: a randomized controlled study","volume":"114","author":"Futier","year":"2011","journal-title":"Anesthesiology"},{"issue":"10","key":"10.1378\/chest.12-0424_bib18","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1007\/s00134-006-0301-8","article-title":"Patient-ventilator asynchrony during assisted mechanical ventilation","volume":"32","author":"Thille","year":"2006","journal-title":"Intensive Care Med"},{"issue":"6","key":"10.1378\/chest.12-0424_bib19","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1007\/s00134-009-1456-x","article-title":"Discomfort associated with underhumidified high-flow oxygen therapy in critically ill patients","volume":"35","author":"Chanques","year":"2009","journal-title":"Intensive Care Med"},{"issue":"10","key":"10.1378\/chest.12-0424_bib20","first-page":"715","article-title":"Sem: a suitable statistical software adaptated for research in oncology [in French]","volume":"87","author":"Kwiatkowski","year":"2000","journal-title":"Bull Cancer"},{"issue":"9","key":"10.1378\/chest.12-0424_bib21","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1007\/s00134-008-1163-z","article-title":"Subject-ventilator synchrony during neural versus pneumatically triggered non-invasive helmet ventilation","volume":"34","author":"Moerer","year":"2008","journal-title":"Intensive Care Med"},{"issue":"12","key":"10.1378\/chest.12-0424_bib22","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1007\/s00134-011-2382-2","article-title":"Noninvasive ventilation through a helmet in postextubation hypoxemic patients: physiologic comparison between neurally adjusted ventilatory assist and pressure support ventilation","volume":"37","author":"Cammarota","year":"2011","journal-title":"Intensive Care Med"},{"issue":"1","key":"10.1378\/chest.12-0424_bib23","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s00134-006-0391-3","article-title":"Non-invasive ventilation in chronic obstructive pulmonary disease patients: helmet versus facial mask","volume":"33","author":"Navalesi","year":"2007","journal-title":"Intensive Care Med"},{"issue":"6","key":"10.1378\/chest.12-0424_bib24","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1097\/CCM.0b013e31819fff93","article-title":"Helmet with specific settings versus facemask for noninvasive ventilation","volume":"37","author":"Vargas","year":"2009","journal-title":"Crit Care Med"},{"issue":"6","key":"10.1378\/chest.12-0424_bib25","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1164\/ajrccm.155.6.9196100","article-title":"Comparison of assisted ventilator modes on triggering, patient effort, and dyspnea","volume":"155","author":"Leung","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"issue":"8","key":"10.1378\/chest.12-0424_bib26","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1007\/s00134-008-1121-9","article-title":"Reduction of patient-ventilator asynchrony by reducing tidal volume during pressure-support ventilation","volume":"34","author":"Thille","year":"2008","journal-title":"Intensive Care Med"},{"issue":"8","key":"10.1378\/chest.12-0424_bib27","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1007\/s00134-007-0713-0","article-title":"Performance of noninvasive ventilation modes on ICU ventilators during pressure support: a bench model study","volume":"33","author":"Vignaux","year":"2007","journal-title":"Intensive Care Med"},{"issue":"6","key":"10.1378\/chest.12-0424_bib28","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1152\/jappl.2000.88.6.2143","article-title":"Analysis of the mechanisms of expiratory asynchrony in pressure support ventilation: a mathematical approach","volume":"88","author":"Yamada","year":"2000","journal-title":"J Appl Physiol"},{"issue":"5","key":"10.1378\/chest.12-0424_bib29","doi-asserted-by":"crossref","first-page":"R116","DOI":"10.1186\/cc7010","article-title":"Pressure support ventilation attenuates ventilator-induced protein modifications in the diaphragm","volume":"12","author":"Futier","year":"2008","journal-title":"Crit Care"},{"issue":"3","key":"10.1378\/chest.12-0424_bib30","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1164\/rccm.201004-0670OC","article-title":"Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans","volume":"183","author":"Jaber","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1378\/chest.12-0424_bib31","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1164\/ajrccm.164.3.2009018","article-title":"Electrical activity of the diaphragm during pressure support ventilation in acute respiratory failure","volume":"164","author":"Beck","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1378\/chest.12-0424_bib32","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1164\/rccm.201106-1094OC","article-title":"Outcomes of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the United States, 1998-2008","volume":"185","author":"Chandra","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1378\/chest.12-0424_bib33","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1378\/chest.128.4.2688","article-title":"Outcomes of patients with acute respiratory failure after abdominal surgery treated with noninvasive positive pressure ventilation","volume":"128","author":"Jaber","year":"2005","journal-title":"Chest"},{"issue":"3","key":"10.1378\/chest.12-0424_bib34","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1378\/chest.08-1747","article-title":"Titration and implementation of neurally adjusted ventilatory assist in critically ill patients","volume":"135","author":"Brander","year":"2009","journal-title":"Chest"},{"issue":"7","key":"10.1378\/chest.12-0424_bib35","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1007\/s00134-011-2209-1","article-title":"Daily titration of neurally adjusted ventilatory assist using the diaphragm electrical activity","volume":"37","author":"Roz\u00e9","year":"2011","journal-title":"Intensive Care Med"},{"issue":"10","key":"10.1378\/chest.12-0424_bib36","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1164\/rccm.200407-880OC","article-title":"Impact of expiratory trigger setting on delayed cycling and inspiratory muscle workload","volume":"172","author":"Tassaux","year":"2005","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213600100?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213600100?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T06:32:34Z","timestamp":1757917954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369213600100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0012369213600100"],"URL":"https:\/\/doi.org\/10.1378\/chest.12-0424","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurally Adjusted Ventilatory Assist vs Pressure Support Ventilation for Noninvasive Ventilation During Acute Respiratory Failure","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.12-0424","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}