{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:08:44Z","timestamp":1789420124978,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1378\/chest.12-0528","type":"journal-article","created":{"date-parts":[[2013,7,27]],"date-time":"2013-07-27T03:53:58Z","timestamp":1374897238000},"page":"1330-1336","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":154,"title":["Management of Pulmonary Arterial Hypertension During Pregnancy"],"prefix":"10.1016","volume":"143","author":[{"given":"Alexander G.","family":"Duarte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shibu","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeenat","family":"Safdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis D.","family":"Pacheco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Feldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bennet","family":"deBoisblanc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1378\/chest.12-0528_bib1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJM199701093360207","article-title":"Primary pulmonary hypertension","volume":"336","author":"Rubin","year":"1997","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1378\/chest.12-0528_bib2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1378\/chest.10-0075","article-title":"The changing picture of patients with pulmonary arterial hypertension in the United States: how REVEAL differs from historic and non-US Contemporary Registries","volume":"139","author":"Frost","year":"2011","journal-title":"Chest"},{"key":"10.1378\/chest.12-0528_bib3","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/00006254-196408000-00001","article-title":"Primary pulmonary hypertension in pregnancy","volume":"19","author":"McCaffrey","year":"1964","journal-title":"Obstet Gynecol Surv"},{"issue":"7","key":"10.1378\/chest.12-0528_bib4","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1016\/S0735-1097(98)00162-4","article-title":"Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996","volume":"31","author":"Weiss","year":"1998","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1378\/chest.12-0528_bib5","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/00000542-200506000-00012","article-title":"Severe pulmonary hypertension during pregnancy: mode of delivery and anesthetic management of 15 consecutive cases","volume":"102","author":"Bonnin","year":"2005","journal-title":"Anesthesiology"},{"issue":"suppl 1","key":"10.1378\/chest.12-0528_bib6","doi-asserted-by":"crossref","first-page":"35S","DOI":"10.1378\/chest.126.1_suppl.35S","article-title":"Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines","volume":"126","author":"Badesch","year":"2004","journal-title":"Chest"},{"key":"10.1378\/chest.12-0528_bib7","doi-asserted-by":"crossref","first-page":"c7434","DOI":"10.1136\/bmj.c7434","article-title":"US hospital loses Catholic designation after performing a lifesaving abortion","volume":"341","author":"Tanne","year":"2010","journal-title":"BMJ"},{"issue":"1","key":"10.1378\/chest.12-0528_bib8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0020-7292(00)00330-1","article-title":"The scope and limits of conscientious objection","volume":"71","author":"Dickens","year":"2000","journal-title":"Int J Gynaecol Obstet"},{"issue":"suppl 1","key":"10.1378\/chest.12-0528_bib9","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/j.jacc.2009.04.011","article-title":"Diagnosis and assessment of pulmonary arterial hypertension","volume":"54","author":"Badesch","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1378\/chest.12-0528_bib10","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/eurheartj\/ehp022","article-title":"A meta-analysis of randomized controlled trials in pulmonary arterial hypertension","volume":"30","author":"Gali\u00e8","year":"2009","journal-title":"Eur Heart J"},{"issue":"4","key":"10.1378\/chest.12-0528_bib11","first-page":"494","article-title":"Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators","volume":"93","author":"Easterling","year":"1999","journal-title":"Obstet Gynecol"},{"issue":"3","key":"10.1378\/chest.12-0528_bib12","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1378\/chest.119.3.973","article-title":"Pregnancy and primary pulmonary hypertension: successful outcome with epoprostenol therapy","volume":"119","author":"Stewart","year":"2001","journal-title":"Chest"},{"issue":"3","key":"10.1378\/chest.12-0528_bib13","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1378\/chest.124.3.1170","article-title":"Successful management of pregnancy in a patient with eisenmenger syndrome with epoprostenol","volume":"124","author":"Geohas","year":"2003","journal-title":"Chest"},{"issue":"5 pt 2","key":"10.1378\/chest.12-0528_bib14","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1097\/01.AOG.0000164074.64137.f1","article-title":"Pregnancy outcome in patients with pulmonary arterial hypertension receiving prostacyclin therapy","volume":"106","author":"Bendayan","year":"2005","journal-title":"Obstet Gynecol"},{"issue":"3","key":"10.1378\/chest.12-0528_bib15","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1159\/000287638","article-title":"Favorable outcome of pregnancy with an elective use of epoprostenol and sildenafil in women with severe pulmonary hypertension","volume":"115","author":"Goland","year":"2010","journal-title":"Cardiology"},{"issue":"3","key":"10.1378\/chest.12-0528_bib16","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/eurheartj\/ehn597","article-title":"Has there been any progress made on pregnancy outcomes among women with pulmonary arterial hypertension?","volume":"30","author":"B\u00e9dard","year":"2009","journal-title":"Eur Heart J"},{"issue":"11","key":"10.1378\/chest.12-0528_bib17","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/S0002-9149(97)00738-8","article-title":"Cardiovascular function before, during, and after the first and subsequent pregnancies","volume":"80","author":"Clapp","year":"1997","journal-title":"Am J Cardiol"},{"issue":"4","key":"10.1378\/chest.12-0528_bib18","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1136\/hrt.2003.027888","article-title":"Pregnancy in heart disease","volume":"90","author":"Thorne","year":"2004","journal-title":"Heart"},{"issue":"4","key":"10.1378\/chest.12-0528_bib19","doi-asserted-by":"crossref","first-page":"H1528","DOI":"10.1152\/ajpheart.01031.2005","article-title":"Impaired left ventricular filling due to right-to-left ventricular interaction in patients with pulmonary arterial hypertension","volume":"290","author":"Gan","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"6","key":"10.1378\/chest.12-0528_bib20","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/S0735-1097(86)80300-X","article-title":"Doppler echocardiographic assessment of impaired left ventricular filling in patients with right ventricular pressure overload due to primary pulmonary hypertension","volume":"8","author":"Louie","year":"1986","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1378\/chest.12-0528_bib21","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000107786","article-title":"Serial hemodynamics and complications of pregnancy in severe pulmonary arterial hypertension","volume":"109","author":"Nahapetian","year":"2008","journal-title":"Cardiology"},{"issue":"5","key":"10.1378\/chest.12-0528_bib22","doi-asserted-by":"crossref","first-page":"R169","DOI":"10.1186\/cc9264","article-title":"Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review","volume":"14","author":"Price","year":"2010","journal-title":"Crit Care"},{"issue":"suppl","key":"10.1378\/chest.12-0528_bib23","first-page":"64002S","article-title":"Pregnancy and pulmonary arterial hypertension: successful management of 37 consecutive patients","volume":"134","author":"Zwicke","year":"2008","journal-title":"Chest"},{"issue":"4","key":"10.1378\/chest.12-0528_bib24","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0735-1097(02)02012-0","article-title":"Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival","volume":"40","author":"Sitbon","year":"2002","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1378\/chest.12-0528_bib25","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1161\/01.CIR.0000029100.82385.58","article-title":"Survival in primary pulmonary hypertension: the impact of epoprostenol therapy","volume":"106","author":"McLaughlin","year":"2002","journal-title":"Circulation"},{"issue":"5","key":"10.1378\/chest.12-0528_bib26","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1471-0528.2009.02492.x","article-title":"Improved survival in pregnancy and pulmonary hypertension using a multiprofessional approach","volume":"117","author":"Kiely","year":"2010","journal-title":"BJOG"},{"issue":"4","key":"10.1378\/chest.12-0528_bib27","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1097\/01.AOG.0000308710.86880.a6","article-title":"Pregnancy outcomes in systemic sclerosis, primary pulmonary hypertension, and sickle cell disease","volume":"111","author":"Chakravarty","year":"2008","journal-title":"Obstet Gynecol"},{"issue":"3","key":"10.1378\/chest.12-0528_bib28","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/ACO.0b013e32833953fb","article-title":"Anesthesia for patients with pulmonary hypertension","volume":"23","author":"Pritts","year":"2010","journal-title":"Curr Opin Anaesthesiol"},{"issue":"10","key":"10.1378\/chest.12-0528_bib29","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1136\/hrt.2006.095240","article-title":"Risks of contraception and pregnancy in heart disease","volume":"92","author":"Thorne","year":"2006","journal-title":"Heart"},{"issue":"4","key":"10.1378\/chest.12-0528_bib30","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1164\/rccm.200605-598OE","article-title":"Pregnancy and chronic progressive pulmonary disease","volume":"175","author":"Wexler","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"10.1378\/chest.12-0528_bib31","first-page":"787","article-title":"Dilatation and evacuation during the second trimester of pregnancy in a woman with primary pulmonary hypertension. A case report","volume":"33","author":"Bowers","year":"1988","journal-title":"J Reprod Med"},{"issue":"4","key":"10.1378\/chest.12-0528_bib32","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1177\/0310057X9402200426","article-title":"Anaesthetic management for laparoscopic sterilisation and termination of pregnancy in a patient with severe primary pulmonary hypertension","volume":"22","author":"Myles","year":"1994","journal-title":"Anaesth Intensive Care"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213603311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213603311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T06:36:41Z","timestamp":1757918201000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369213603311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0012369213603311"],"URL":"https:\/\/doi.org\/10.1378\/chest.12-0528","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of Pulmonary Arterial Hypertension During Pregnancy","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.12-0528","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}