{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T20:36:22Z","timestamp":1791750982465,"version":"4.3.4"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1378\/chest.12-0964","type":"journal-article","created":{"date-parts":[[2013,6,6]],"date-time":"2013-06-06T17:00:31Z","timestamp":1370538031000},"page":"138-145","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"title":["A Clinical Prognostic Model for the Identification of Low-Risk Patients With Acute Symptomatic Pulmonary Embolism and Active Cancer"],"prefix":"10.1016","volume":"143","author":[{"given":"Paul L.","family":"den Exter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Trujillo-Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Muriel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menno V.","family":"Huisman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Monreal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"16","key":"10.1378\/chest.12-0964_bib1","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1161\/CIR.0b013e318214914f","article-title":"Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association","volume":"123","author":"Jaff","year":"2011","journal-title":"Circulation"},{"issue":"suppl 6","key":"10.1378\/chest.12-0964_bib2","doi-asserted-by":"crossref","first-page":"454S","DOI":"10.1378\/chest.08-0658","article-title":"Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians evidence-based clinical practice guidelines (8th ed)","volume":"133","author":"Kearon","year":"2008","journal-title":"Chest"},{"issue":"18","key":"10.1378\/chest.12-0964_bib3","first-page":"2276","article-title":"Guidelines on the diagnosis and management of acute pulmonary embolism the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)","volume":"29","author":"Torbicki","year":"2008","journal-title":"Eur Heart J"},{"issue":"9785","key":"10.1378\/chest.12-0964_bib4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0140-6736(11)60824-6","article-title":"Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial","volume":"378","author":"Aujesky","year":"2011","journal-title":"Lancet"},{"issue":"4","key":"10.1378\/chest.12-0964_bib5","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1055\/s-0037-1614065","article-title":"Predicting adverse outcome in patients with acute pulmonary embolism: a risk score","volume":"84","author":"Wicki","year":"2000","journal-title":"Thromb Haemost"},{"issue":"8","key":"10.1378\/chest.12-0964_bib6","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1164\/rccm.200506-862OC","article-title":"Derivation and validation of a prognostic model for pulmonary embolism","volume":"172","author":"Aujesky","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"15","key":"10.1378\/chest.12-0964_bib7","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1001\/archinternmed.2010.199","article-title":"Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism","volume":"170","author":"Jim\u00e9nez","year":"2010","journal-title":"Arch Intern Med"},{"issue":"4","key":"10.1378\/chest.12-0964_bib8","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1093\/eurheartj\/ehi588","article-title":"Validation of a model to predict adverse outcomes in patients with pulmonary embolism","volume":"27","author":"Aujesky","year":"2006","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1378\/chest.12-0964_bib9","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1365-2796.2007.01785.x","article-title":"Validation of a clinical prognostic model to identify low-risk patients with pulmonary embolism","volume":"261","author":"Aujesky","year":"2007","journal-title":"J Intern Med"},{"issue":"1","key":"10.1378\/chest.12-0964_bib10","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1378\/chest.06-2921","article-title":"Prognostic models for selecting patients with acute pulmonary embolism for initial outpatient therapy","volume":"132","author":"Jim\u00e9nez","year":"2007","journal-title":"Chest"},{"issue":"5","key":"10.1378\/chest.12-0964_bib11","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1097\/00063198-200109000-00019","article-title":"Outpatient treatment of patients with deep-vein thrombosis or pulmonary embolism","volume":"7","author":"Wells","year":"2001","journal-title":"Curr Opin Pulm Med"},{"issue":"2","key":"10.1378\/chest.12-0964_bib12","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1148\/radiology.185.2.1410342","article-title":"Central pulmonary thromboembolism: diagnosis with spiral volumetric CT with the single-breath-hold technique\u2014comparison with pulmonary angiography","volume":"185","author":"Remy-Jardin","year":"1992","journal-title":"Radiology"},{"issue":"13","key":"10.1378\/chest.12-0964_bib13","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1161\/CIRCULATIONAHA.107.726232","article-title":"Clinical predictors for fatal pulmonary embolism in 15,520 patients with venous thromboembolism: findings from the Registro Informatizado de la Enfermedad TromboEmbolica venosa (RIETE) Registry","volume":"117","author":"Laporte","year":"2008","journal-title":"Circulation"},{"issue":"20","key":"10.1378\/chest.12-0964_bib14","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1001\/jama.1990.03440200057023","article-title":"Value of the ventilation\/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED)","volume":"263","author":"The PIOPED Investigators","year":"1990","journal-title":"JAMA"},{"issue":"12","key":"10.1378\/chest.12-0964_bib15","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.7326\/0003-4819-129-12-199812150-00009","article-title":"The role of venous ultrasonography in the diagnosis of suspected deep venous thrombosis and pulmonary embolism","volume":"129","author":"Kearon","year":"1998","journal-title":"Ann Intern Med"},{"issue":"17","key":"10.1378\/chest.12-0964_bib16","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1200\/JCO.2010.34.0984","article-title":"Risk of recurrent venous thromboembolism and mortality in patients with cancer incidentally diagnosed with pulmonary embolism: a comparison with symptomatic patients","volume":"29","author":"den Exter","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1378\/chest.12-0964_bib17","series-title":"Applied Logistic Regression","author":"Hosmer","year":"1989"},{"issue":"6","key":"10.1378\/chest.12-0964_bib18","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1136\/thorax.58.6.470","article-title":"British Thoracic Society guidelines for the management of suspected acute pulmonary embolism","volume":"58","author":"British Thoracic Society Standards of Care Committee Pulmonary Embolism Guideline Development Group","year":"2003","journal-title":"Thorax"},{"issue":"3","key":"10.1378\/chest.12-0964_bib19","doi-asserted-by":"crossref","first-page":"204","DOI":"10.7326\/0003-4819-146-3-200702060-00149","article-title":"Management of venous thromboembolism: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians","volume":"146","author":"Snow","year":"2007","journal-title":"Ann Intern Med"},{"issue":"24","key":"10.1378\/chest.12-0964_bib20","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1161\/CIRCULATIONAHA.111.051177","article-title":"Predictive value of the high-sensitivity troponin T assay and the simplified Pulmonary Embolism Severity Index in hemodynamically stable patients with acute pulmonary embolism: a prospective validation study","volume":"124","author":"Lankeit","year":"2011","journal-title":"Circulation"},{"issue":"3","key":"10.1378\/chest.12-0964_bib21","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1160\/TH08-02-0125","article-title":"Predicting recurrences or major bleeding in cancer patients with venous thromboembolism. Findings from the RIETE Registry","volume":"100","author":"Trujillo-Santos","year":"2008","journal-title":"Thromb Haemost"},{"issue":"9","key":"10.1378\/chest.12-0964_bib22","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1111\/j.1538-7836.2006.02082.x","article-title":"Fatal pulmonary embolism and fatal bleeding in cancer patients with venous thromboembolism: findings from the RIETE registry","volume":"4","author":"Monreal","year":"2006","journal-title":"J Thromb Haemost"},{"issue":"11","key":"10.1378\/chest.12-0964_bib23","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1111\/j.1538-7836.2004.01012.x","article-title":"The outcome after treatment of venous thromboembolism is different in surgical and acutely ill medical patients. Findings from the RIETE registry","volume":"2","author":"Monreal","year":"2004","journal-title":"J Thromb Haemost"},{"issue":"5","key":"10.1378\/chest.12-0964_bib24","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/j.1538-7836.2005.01304.x","article-title":"The influence of extreme body weight on clinical outcome of patients with venous thromboembolism: findings from a prospective registry (RIETE)","volume":"3","author":"Barba","year":"2005","journal-title":"J Thromb Haemost"},{"issue":"7659","key":"10.1378\/chest.12-0964_bib25","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1136\/bmj.39609.449676.25","article-title":"Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2","volume":"336","author":"Hippisley-Cox","year":"2008","journal-title":"BMJ"},{"issue":"6","key":"10.1378\/chest.12-0964_bib26","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.thromres.2011.08.025","article-title":"Does the Pulmonary Embolism Severity Index accurately identify low risk patients eligible for outpatient treatment?","volume":"129","author":"Erkens","year":"2012","journal-title":"Thromb Res"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213600239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369213600239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T06:31:55Z","timestamp":1757917915000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369213600239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0012369213600239"],"URL":"https:\/\/doi.org\/10.1378\/chest.12-0964","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Clinical Prognostic Model for the Identification of Low-Risk Patients With Acute Symptomatic Pulmonary Embolism and Active Cancer","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.12-0964","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}