{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T11:22:10Z","timestamp":1791112930835,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1378\/chest.125.3.1071","type":"journal-article","created":{"date-parts":[[2004,3,8]],"date-time":"2004-03-08T22:43:00Z","timestamp":1078785780000},"page":"1071-1076","source":"Crossref","is-referenced-by-count":32,"title":["HIV-1 Infection Does Not Impair Human Alveolar Macrophage Phagocytic Function Unless Combined With Cigarette Smoking"],"prefix":"10.1016","volume":"125","author":[{"given":"Andreas","family":"Elssner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo E.","family":"Carter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Yunger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D.","family":"Wewers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1378\/chest.125.3.1071_bib1","first-page":"250","article-title":"Bronchoalveolar lavage","volume":"135","author":"Reynolds","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.125.3.1071_bib2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1034\/j.1600-065X.2000.917306.x","article-title":"Innate immunity and pulmonary host defense","volume":"173","author":"Zhang","year":"2000","journal-title":"Immunol Rev"},{"key":"10.1378\/chest.125.3.1071_bib3","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1182\/blood.V68.1.281.281","article-title":"Human T lymphotropic virus type III infection of human alveolar macrophages","volume":"68","author":"Salahuddin","year":"1986","journal-title":"Blood"},{"key":"10.1378\/chest.125.3.1071_bib4","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1084\/jem.174.6.1477","article-title":"Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes","volume":"174","author":"Weinberg","year":"1991","journal-title":"J Exp Med"},{"key":"10.1378\/chest.125.3.1071_bib5","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1126\/science.276.5320.1857","article-title":"Macrophages as a source of HIV during opportunistic infection","volume":"276","author":"Orenstein","year":"1997","journal-title":"Science"},{"key":"10.1378\/chest.125.3.1071_bib6","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1164\/ajrccm.160.6.9902099","article-title":"Enhancedin vivohuman immunodeficiency virus-1 replication in the lungs of human immunodeficiency virus-infected persons withPneumocystis cariniipneumonia","volume":"160","author":"Koziel","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.125.3.1071_bib7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1172\/JCI11918","article-title":"Hostile takeovers: viral appropriation of the NF-\u03baB pathway","volume":"107","author":"Hiscott","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.125.3.1071_bib8","first-page":"233","article-title":"Infection of human monocytes\/macrophages by HIV-1: effect on secretion of IL-1 activity","volume":"64","author":"Roy","year":"1988","journal-title":"Immunol"},{"key":"10.1378\/chest.125.3.1071_bib9","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1172\/JCI111637","article-title":"Monocyte function in the acquired immune deficiency syndrome: defective chemotaxis","volume":"74","author":"Smith","year":"1984","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.125.3.1071_bib10","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1093\/infdis\/152.2.409","article-title":"Defective reticuloendothelial system Fc-receptor function in patients with acquired immunodeficiency syndrome","volume":"152","author":"Bender","year":"1985","journal-title":"J Infect Dis"},{"key":"10.1378\/chest.125.3.1071_bib11","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1172\/JCI560","article-title":"Reduced binding and phagocytosis of pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor downregulation","volume":"102","author":"Koziel","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.125.3.1071_bib12","doi-asserted-by":"crossref","first-page":"6132","DOI":"10.4049\/jimmunol.154.11.6132","article-title":"HIV-1 infection of human macrophages impairs phagocytosis and killing ofToxoplasma gondii","volume":"154","author":"Biggs","year":"1995","journal-title":"J Immunol"},{"key":"10.1378\/chest.125.3.1071_bib13","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/00000441-199003000-00003","article-title":"The effect of HIV infection on phagocytosis and killing ofStaphylococcus aureusby human pulmonary alveolar macrophages","volume":"299","author":"Musher","year":"1990","journal-title":"Am J Med Sci"},{"key":"10.1378\/chest.125.3.1071_bib14","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1086\/324080","article-title":"Opsonic phagocytosis ofStreptococcus pneumoniaeby alveolar macrophages is not impaired in human immunodeficiency virus-infected Malawian adults","volume":"184","author":"Gordon","year":"2001","journal-title":"J Infect Dis"},{"key":"10.1378\/chest.125.3.1071_bib15","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1056\/NEJM198704233161704","article-title":"Replacement therapy for \u03b1 1-antitrypsin deficiency associated with emphysema","volume":"316","author":"Wewers","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.125.3.1071_bib16","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1056\/NEJM196702232760801","article-title":"The depressant effect of cigarette smoke on thein vitroantibacterial activity of alveolar macrophages","volume":"276","author":"Green","year":"1967","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.125.3.1071_bib17","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1128\/IAI.20.2.468-475.1978","article-title":"Cigarette smoke and phagocyte function: effect of chronic exposurein vivoand acute exposurein vitro","volume":"20","author":"Thomas","year":"1978","journal-title":"Infect Immun"},{"key":"10.1378\/chest.125.3.1071_bib18","first-page":"311","article-title":"Functional evaluation of lung macrophages from cigarette smokers and nonsmokers","volume":"32","author":"Fisher","year":"1982","journal-title":"J Reticuloendothel Soc"},{"key":"10.1378\/chest.125.3.1071_bib19","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1378\/chest.119.1.196","article-title":"BAL and serum IgG levels in healthy asymptomatic HIV-infected patients","volume":"119","author":"Fahy","year":"2001","journal-title":"Chest"},{"key":"10.1378\/chest.125.3.1071_bib20","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1056\/NEJM199509283331305","article-title":"Bacterial pneumonia in persons infected with the human immunodeficiency virus","volume":"333","author":"Hirschtick","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.125.3.1071_bib21","first-page":"1121","article-title":"The association between cigarette smoking and selected HIV-related medical conditions","volume":"10","author":"Conley","year":"1996","journal-title":"AIDS"},{"key":"10.1378\/chest.125.3.1071_bib22","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1164\/ajrccm.150.6.7952605","article-title":"Drug smoking,Pneumocystis cariniipneumonia, and immunosuppression increase risk of bacterial pneumonia in human immunodeficiency virus-seropositive injection drug users","volume":"150","author":"Caiaffa","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.125.3.1071_bib23","doi-asserted-by":"crossref","first-page":"369","DOI":"10.7326\/0003-4819-132-5-200003070-00006","article-title":"Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers","volume":"132","author":"Diaz","year":"2000","journal-title":"Ann Intern Med"},{"key":"10.1378\/chest.125.3.1071_bib24","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/00002030-199304000-00015","article-title":"The epidemiology of HIV-1 infection of the lung in AIDS patients","volume":"7","author":"Clarke","year":"1993","journal-title":"AIDS"},{"key":"10.1378\/chest.125.3.1071_bib25","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1164\/ajrccm.158.5.9802035","article-title":"Cigarette smoking in HIV infection induces a suppressive inflammatory environment in the lung","volume":"158","author":"Wewers","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.125.3.1071_bib26","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/00002030-199405000-00006","article-title":"Impaired alveolar macrophage accessory cell function and reduced incidence of lymphocytic alveolitis in HIV-infected patients who smoke","volume":"8","author":"Twigg","year":"1994","journal-title":"AIDS"},{"key":"10.1378\/chest.125.3.1071_bib27","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1056\/NEJM200003093421002","article-title":"Cigarette smoking and invasive pneumococcal disease: Active Bacterial Core Surveillance Team","volume":"342","author":"Nuorti","year":"2000","journal-title":"N Engl J Med"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215319498?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215319498?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T17:10:31Z","timestamp":1705079431000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215319498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S0012369215319498"],"URL":"https:\/\/doi.org\/10.1378\/chest.125.3.1071","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}