{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:25:19Z","timestamp":1790821519967,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1378\/chest.127.2.522","type":"journal-article","created":{"date-parts":[[2005,2,10]],"date-time":"2005-02-10T23:54:00Z","timestamp":1108079640000},"page":"522-529","source":"Crossref","is-referenced-by-count":78,"title":["Bronchial Constriction and Inhaled Colistin in Cystic Fibrosis"],"prefix":"10.1016","volume":"127","author":[{"given":"Ghassan A.","family":"Alothman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muslim M.","family":"Alsaadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon L.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"O'Drowsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Louca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan L.","family":"Coates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1378\/chest.127.2.522_bib1","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/S0022-3476(05)82653-8","article-title":"Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization withPseudomonas aeruginosa","volume":"116","author":"Kerem","year":"1990","journal-title":"J Pediatr"},{"key":"10.1378\/chest.127.2.522_bib2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/ppul.1950070413","article-title":"Safety of aerosolized tobramycin administration for 3 months to patients with cystic fibrosis","volume":"7","author":"Smith","year":"1989","journal-title":"Pediatr Pulmonol"},{"key":"10.1378\/chest.127.2.522_bib3","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1097\/00007890-199709150-00015","article-title":"Use of aerosolized colistin sodium in cystic fibrosis patients awaiting lung transplantation","volume":"64","author":"Bauldoff","year":"1997","journal-title":"Transplantation"},{"key":"10.1378\/chest.127.2.522_bib4","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/S0140-6736(85)92222-6","article-title":"Nebulized colomycin for early Pseudomonas colonization in cystic fibrosis [letter]","volume":"I","author":"Littlewood","year":"1985","journal-title":"Lancet"},{"key":"10.1378\/chest.127.2.522_bib5","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1183\/09031936.97.10091995","article-title":"Nebulization and anti-Pseudomonas aeruginosaactivity of colistin","volume":"10","author":"Diot","year":"1997","journal-title":"Eur Respir J"},{"key":"10.1378\/chest.127.2.522_bib6","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/jac\/39.2.255","article-title":"A reassessment of thein vitroactivity of colistin sulphomethate sodium","volume":"39","author":"Catchpole","year":"1997","journal-title":"J Antimicrob Chemother"},{"key":"10.1378\/chest.127.2.522_bib7","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/jac\/19.6.831","article-title":"Colistin inhalation therapy in cystic fibrosis patients with chronicPseudomonas aeruginosalung infection","volume":"19","author":"Jensen","year":"1987","journal-title":"J Antimicrob Chemother"},{"key":"10.1378\/chest.127.2.522_bib8","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1177\/106002809102501101","article-title":"Toxicity of colistin in cystic fibrosis patients","volume":"25","author":"Bosso","year":"1998","journal-title":"DICP"},{"key":"10.1378\/chest.127.2.522_bib9","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/(SICI)1099-0496(199705)23:5<330::AID-PPUL4>3.0.CO;2-O","article-title":"Antibiotic treatment of initial colonization withPseudomonas aeruginosapostpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis","volume":"23","author":"Frederiksen","year":"1997","journal-title":"Pediatr Pulmonol"},{"key":"10.1378\/chest.127.2.522_bib10","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/(SICI)1099-0496(199909)28:3<159::AID-PPUL1>3.0.CO;2-1","article-title":"Changing epidemiology ofPseudomonas aeruginosainfection in Danish cystic fibrosis patients (1974\u20131995)","volume":"28","author":"Frederiksen","year":"1999","journal-title":"Pediatr Pulmonol"},{"key":"10.1378\/chest.127.2.522_bib11","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1183\/09031936.02.00248102","article-title":"A randomized clinical trial of nebulised tobramycin or colistin in cystic fibrosis","volume":"20","author":"Hodson","year":"2003","journal-title":"Eur Respir J"},{"key":"10.1378\/chest.127.2.522_bib12","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/thx.52.7.656","article-title":"Effect of tonicity of nebulized colistin on chest tightness and pulmonary function in adults with cystic fibrosis","volume":"52","author":"Dodd","year":"1997","journal-title":"Thorax"},{"key":"10.1378\/chest.127.2.522_bib13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0954-6111(94)90028-0","article-title":"Nebulized colistin causes chest tightness in adults with cystic fibrosis","volume":"88","author":"Maddison","year":"1994","journal-title":"Respir Med"},{"key":"10.1378\/chest.127.2.522_bib14","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1365-2125.1988.tb03305.x","article-title":"Adverse reactions to the non-drug constituents of nebuliser solutions","volume":"25","author":"Beasley","year":"1988","journal-title":"Br J Clin Pharmacol"},{"key":"10.1378\/chest.127.2.522_bib15","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1136\/bmj.283.6302.1285","article-title":"Bronchial hyperreactivity in response to inhalation of ultrasonically nebulised solutions of distilled water and saline","volume":"283","author":"Schoeffel","year":"1981","journal-title":"BMJ"},{"key":"10.1378\/chest.127.2.522_bib16","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1183\/09031936.93.03101114","article-title":"Bronchial response to nebulized antibiotics in children with cystic fibrosis","volume":"3","author":"Chua","year":"1990","journal-title":"Eur Respir J"},{"key":"10.1378\/chest.127.2.522_bib17","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1136\/adc.84.5.432","article-title":"Bronchoconstriction following nebulised colistin in cystic fibrosis","volume":"84","author":"Cunningham","year":"2001","journal-title":"Arch Dis Child"},{"key":"10.1378\/chest.127.2.522_bib18","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1089\/08942680152744677","article-title":"Evaluation of four breath-enhanced nebulizers for home use","volume":"14","author":"Ho","year":"2001","journal-title":"J Aerosol Med"},{"key":"10.1378\/chest.127.2.522_bib19","first-page":"378","article-title":"Cystic fibrosis inhalation therapy: stability of a combined salbutamol\/colistin solution","volume":"22","author":"Roberts","year":"1992","journal-title":"Aust J Pharm"},{"key":"10.1378\/chest.127.2.522_bib20","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1042\/bj1810623","article-title":"Further studies on the structural requirements for polypeptide-mediated histamine release from rat mast cells","volume":"181","author":"Jasani","year":"1979","journal-title":"Biochem J"},{"key":"10.1378\/chest.127.2.522_bib21","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1164\/ajrccm.152.3.7663792","article-title":"Standardization of spirometry: 1994 update","volume":"152","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.127.2.522_bib22","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1378\/chest.122.3.930","article-title":"Evaluation of bronchial constriction in cystic fibrosis children after inhaling two different preparations of tobramycin","volume":"122","author":"Alothman","year":"2002","journal-title":"Chest"},{"key":"10.1378\/chest.127.2.522_bib23","first-page":"1085","article-title":"Five to seven-year course of pulmonary function in cystic fibrosis","volume":"114","author":"Corey","year":"1976","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.127.2.522_bib24","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1378\/chest.119.1.250","article-title":"Nebulizer choice for treatment of cystic fibrosis patients with inhaled colistin","volume":"119","author":"Katz","year":"2001","journal-title":"Chest"},{"key":"10.1378\/chest.127.2.522_bib25","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1378\/chest.113.4.951","article-title":"A comparison of the availability of tobramycin for inhalation from vented versus unvented nebulizers","volume":"113","author":"Coates","year":"1998","journal-title":"Chest"},{"key":"10.1378\/chest.127.2.522_bib26","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1089\/jam.1998.11.101","article-title":"Factors influencing the rate of drug output during the course of wet nebulization","volume":"11","author":"Coates","year":"1998","journal-title":"J Aerosol Med"},{"key":"10.1378\/chest.127.2.522_bib27","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1089\/jam.1998.11.89","article-title":"The use of osmometry as a means of determining changes in drug concentration during jet nebulization","volume":"11","author":"Kwong","year":"1998","journal-title":"J Aerosol Med"},{"key":"10.1378\/chest.127.2.522_bib28","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1378\/chest.111.1.204","article-title":"A comparison of pulmonary availability between Ventolin (albuterol) nebules and Ventolin (albuterol) respirator solution","volume":"111","author":"Mac Neish","year":"1997","journal-title":"Chest"},{"key":"10.1378\/chest.127.2.522_bib29","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1183\/09031936.94.07122185","article-title":"The influence of age on aerosol deposition in children with cystic fibrosis","volume":"7","author":"Chua","year":"1994","journal-title":"Eur Respir J"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215325903?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215325903?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T04:24:09Z","timestamp":1683001449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215325903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0012369215325903"],"URL":"https:\/\/doi.org\/10.1378\/chest.127.2.522","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}