{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:46:17Z","timestamp":1790700377917,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1378\/chest.127.5.1729","type":"journal-article","created":{"date-parts":[[2005,5,11]],"date-time":"2005-05-11T23:03:47Z","timestamp":1115852627000},"page":"1729-1743","source":"Crossref","is-referenced-by-count":108,"title":["A Multidisciplinary Community Hospital Program for Early and Rapid Resuscitation of Shock in Nontrauma Patients"],"prefix":"10.1016","volume":"127","author":[{"given":"Frank","family":"Sebat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amjad A.","family":"Musthafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Watnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Saari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1378\/chest.127.5.1729_bib1","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1056\/NEJMoa010307","article-title":"Early goal-directed therapy in the treatment of severe sepsis and septic shock","volume":"345","author":"Rivers","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.127.5.1729_bib2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.5694\/j.1326-5377.1999.tb123492.x","article-title":"Recognising clinical instability in hospital patients before cardiac arrest or unplanned admission to intensive care: a pilot study in a tertiary-care hospital","volume":"171","author":"Buist","year":"1999","journal-title":"Med J Aust"},{"key":"10.1378\/chest.127.5.1729_bib3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.7326\/0003-4819-131-1-199907060-00010","article-title":"Cardiogenic shock","volume":"131","author":"Hollenberg","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1378\/chest.127.5.1729_bib4","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1097\/00003246-199812000-00045","article-title":"Has the mortality of septic shock changed with time","volume":"26","author":"Friedman","year":"1998","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib5","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1097\/00003246-200107001-00035","article-title":"Epidemiology of sepsis: an update","volume":"29","author":"Angus","year":"2001","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib6","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1056\/NEJMp020096","article-title":"Treating sepsis","volume":"347","author":"Wenzel","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.127.5.1729_bib7","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1213\/00000539-196711000-00011","article-title":"A shock team in a general hospital","volume":"46","author":"Frank","year":"1967","journal-title":"Anesth Analg"},{"key":"10.1378\/chest.127.5.1729_bib8","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1177\/0310057X9502300210","article-title":"The medical emergency team","volume":"23","author":"Lee","year":"1995","journal-title":"Anaesth Intensive Care"},{"key":"10.1378\/chest.127.5.1729_bib9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.5694\/j.1326-5377.2000.tb125627.x","article-title":"Rates of in-hospital arrests, deaths and intensive care admissions: the effect of a medical emergency team","volume":"173","author":"Bristow","year":"2000","journal-title":"Med J Aust"},{"key":"10.1378\/chest.127.5.1729_bib10","doi-asserted-by":"crossref","first-page":"283","DOI":"10.5694\/j.1326-5377.2003.tb05548.x","article-title":"A prospective before-and-after trial of a medical emergency team","volume":"179","author":"Bellomo","year":"2003","journal-title":"Med J Aust"},{"key":"10.1378\/chest.127.5.1729_bib11","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1136\/bmj.324.7334.387","article-title":"Effects of a medical emergency team on reduction of incidence of and mortality from unexpected cardiac arrests in hospital: preliminary study","author":"Buist","year":"2002","journal-title":"BMJ"},{"key":"10.1378\/chest.127.5.1729_bib12","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1001\/jama.1993.03510220055034","article-title":"A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients","volume":"270","author":"Boyd","year":"1993","journal-title":"JAMA"},{"key":"10.1378\/chest.127.5.1729_bib13","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1001\/archsurg.1992.01420100033006","article-title":"Prospective trial of supranormal values as goals of resuscitation in severe trauma","volume":"127","author":"Fleming","year":"1992","journal-title":"Arch Surg"},{"key":"10.1378\/chest.127.5.1729_bib14","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1378\/chest.102.1.216","article-title":"Elevation of cardiac output and oxygen delivery improves outcome in septic shock","volume":"102","author":"Tuchschmidt","year":"1992","journal-title":"Chest"},{"key":"10.1378\/chest.127.5.1729_bib15","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1097\/00003246-200208000-00002","article-title":"Meta-analysis of hemodynamic optimization in high-risk patients","volume":"30","author":"Kern","year":"2002","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib16","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1056\/NEJM199406163302404","article-title":"Elevation of systemic oxygen delivery in the treatment of critically ill patients","volume":"330","author":"Hayes","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.127.5.1729_bib17","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1056\/NEJM199510193331601","article-title":"A trial of goal-oriented hemodynamic therapy in critically ill patients: SvO2 Collaborative Group","volume":"333","author":"Gattinoni","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.127.5.1729_bib18","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1097\/00003246-199806000-00019","article-title":"Septic shock: an analysis of outcomes for patients with onset on hospital wards versus intensive care units","volume":"26","author":"Lundberg","year":"1998","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib19","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/00003246-199402000-00014","article-title":"Developing strategies to prevent inhospital cardiac arrest: analyzing responses of physicians and nurses in the hours before the event","volume":"22","author":"Franklin","year":"1994","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib20","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1136\/bmj.316.7148.1853","article-title":"Confidential inquiry into quality of care before admission to intensive care","volume":"316","author":"Mc Quillan","year":"1998","journal-title":"BMJ"},{"key":"10.1378\/chest.127.5.1729_bib21","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1046\/j.1445-5994.2001.00077.x","article-title":"Antecedents to hospital deaths","volume":"31","author":"Hillman","year":"2001","journal-title":"Intern Med J"},{"key":"10.1378\/chest.127.5.1729_bib22","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1136\/bmj.316.7148.1841","article-title":"Suboptimal care of patients before admission to intensive care is caused by a failure to appreciate or apply the ABCs of life support","volume":"316","author":"Garrard","year":"1998","journal-title":"BMJ"},{"key":"10.1378\/chest.127.5.1729_bib23","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/00003246-199902000-00030","article-title":"Effects of an organized critical care service on outcomes and resource utilization: a cohort study","volume":"27","author":"Hanson","year":"1999","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib24","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1001\/jama.1988.03410230064029","article-title":"Impact of critical care physician staffing on patients with septic shock in a university hospital medical intensive care unit","volume":"260","author":"Reynolds","year":"1988","journal-title":"JAMA"},{"key":"10.1378\/chest.127.5.1729_bib25","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1378\/chest.96.1.127","article-title":"Effect on ICU mortality of a full-time critical care specialist","volume":"96","author":"Brown","year":"1989","journal-title":"Chest"},{"key":"10.1378\/chest.127.5.1729_bib26","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1001\/jama.1996.03540040066035","article-title":"Effects of organizational change in the medical intensive care unit of a teaching hospital: a comparison of \u201copen\u201d and \u201cclosed\u201d formats","volume":"276","author":"Carson","year":"1996","journal-title":"JAMA"},{"key":"10.1378\/chest.127.5.1729_bib27","doi-asserted-by":"crossref","first-page":"391","DOI":"10.4065\/72.5.391","article-title":"Effects of a medical intensivist on patient care in a community teaching hospital","volume":"72","author":"Manthous","year":"1997","journal-title":"Mayo Clin Proc"},{"key":"10.1378\/chest.127.5.1729_bib28","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1164\/ajrccm.157.5.9708039","article-title":"A \u201cclosed\u201d medical intensive care unit (MICU) improves resource utilization when compared with an \u201copen\u201d MICU","volume":"157","author":"Multz","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib29","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/00000658-199902000-00001","article-title":"Analysis of the effect of conversion from open to closed surgical intensive care unit","volume":"229","author":"Ghorra","year":"1999","journal-title":"Ann Surg"},{"key":"10.1378\/chest.127.5.1729_bib30","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1001\/jama.281.14.1310","article-title":"Organizational characteristics of intensive care units related to outcomes of abdominal aortic surgery","volume":"281","author":"Pronovost","year":"1999","journal-title":"JAMA"},{"key":"10.1378\/chest.127.5.1729_bib31","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/00003246-199704000-00004","article-title":"A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation","volume":"25","author":"Kollef","year":"1997","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib32","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1378\/chest.118.2.459","article-title":"Protocol weaning of mechanical ventilation in medical and surgical patients by respiratory care practitioners and nurses: effect on weaning time and incidence of ventilator-associated pneumonia","volume":"118","author":"Marelich","year":"2000","journal-title":"Chest"},{"key":"10.1378\/chest.127.5.1729_bib33","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1136\/emj.20.5.418","article-title":"Nurse initiated thrombolysis in the accident and emergency department: safe, accurate, and faster than fast track","volume":"20","author":"Heath","year":"2003","journal-title":"Emerg Med J"},{"key":"10.1378\/chest.127.5.1729_bib34","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1001\/jama.1969.03150150049010","article-title":"The \u201cVIP\u201d approach to the bedside management of shock","volume":"207","author":"Weil","year":"1969","journal-title":"JAMA"},{"key":"10.1378\/chest.127.5.1729_bib35","author":"Weil","year":"1976"},{"key":"10.1378\/chest.127.5.1729_bib36","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1001\/jama.1991.03470090076035","article-title":"Role of early fluid resuscitation in pediatric septic shock","volume":"266","author":"Carcillo","year":"1991","journal-title":"JAMA"},{"key":"10.1378\/chest.127.5.1729_bib37","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0300-9572(00)00175-1","article-title":"Early fluid resuscitation improves outcomes in severely burned children","volume":"45","author":"Barrow","year":"2000","journal-title":"Resuscitation"},{"key":"10.1378\/chest.127.5.1729_bib38","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/S0140-6736(78)90979-0","article-title":"Prospective study of the treatment of septic shock","volume":"1","author":"Ledingham","year":"1978","journal-title":"Lancet"},{"key":"10.1378\/chest.127.5.1729_bib39","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1378\/chest.100.6.1619","article-title":"The APACHE III prognostic system: risk prediction of hospital mortality for critically ill hospitalized adults","volume":"100","author":"Knaus","year":"1991","journal-title":"Chest"},{"key":"10.1378\/chest.127.5.1729_bib40","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1136\/bmj.309.6949.248","article-title":"One and two sided tests of significance","volume":"309","author":"Bland","year":"1994","journal-title":"BMJ"},{"key":"10.1378\/chest.127.5.1729_bib41","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0895-4356(00)00276-6","article-title":"The ethics of sample size: two-sided testing and one-sided thinking","volume":"54","author":"Knottnerus","year":"2001","journal-title":"J Clin Epidemiol"},{"key":"10.1378\/chest.127.5.1729_bib42","first-page":"15","article-title":"Septic shock a deadly enemy","volume":"1","author":"Lias","year":"2004","journal-title":"Los Gatos Daily News"},{"key":"10.1378\/chest.127.5.1729_bib43","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1001\/jama.1985.03360080071032","article-title":"Preventable trauma deaths: a review of trauma care systems development","volume":"254","author":"Cales","year":"1985","journal-title":"JAMA"},{"key":"10.1378\/chest.127.5.1729_bib44","first-page":"979","article-title":"Trauma center: a new concept for the delivery of critical care","volume":"74","author":"Cowley","year":"1977","journal-title":"J Med Soc N J"},{"key":"10.1378\/chest.127.5.1729_bib45","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1097\/00075198-200212000-00019","article-title":"Critical care without walls","volume":"8","author":"Hillman","year":"2002","journal-title":"Curr Opin Crit Care"},{"key":"10.1378\/chest.127.5.1729_bib46","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1097\/00003246-200209000-00014","article-title":"Use of a handheld computer by respiratory care practitioners to improve the efficiency of weaning patients from mechanical ventilation","volume":"30","author":"Iregui","year":"2002","journal-title":"Crit Care Med"},{"key":"10.1378\/chest.127.5.1729_bib47","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1136\/bmj.2.5653.338","article-title":"Effects of treatment on the mortality rate in septicaemia","volume":"2","author":"Chalmers","year":"1969","journal-title":"BMJ"},{"key":"10.1378\/chest.127.5.1729_bib48","first-page":"968","article-title":"Incidence, risk factors, and outcome of severe sepsis and septic shock in adults: a multicenter prospective study in intensive care units","volume":"274","author":"Brun-Buisson","year":"1995","journal-title":"French ICU Group for Severe Sepsis JAMA"},{"key":"10.1378\/chest.127.5.1729_bib49","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1056\/NEJM200103083441001","article-title":"Efficacy and safety of recombinant human activated protein C for severe sepsis","volume":"344","author":"Bernard","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.127.5.1729_bib50","first-page":"16","article-title":"On alert","author":"Scolanboring","year":"2004","journal-title":"Adv Nurses"},{"key":"10.1378\/chest.127.5.1729_bib51","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/00002727-199719040-00005","article-title":"Interventional recovery outside the walls of an intensive care environment","volume":"19","author":"Clark","year":"1997","journal-title":"Crit Care Nurs Q"},{"key":"10.1378\/chest.127.5.1729_bib52","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1053\/jcrc.2003.50002","article-title":"Improving the utilization of medical crisis teams (condition C) at an urban tertiary care hospital","volume":"18","author":"Foraida","year":"2003","journal-title":"J Crit Care"},{"key":"10.1378\/chest.127.5.1729_bib53","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1136\/ewjm.172.4.271","article-title":"Placebo-controlled trials: good science or medical neglect?","volume":"172","author":"Chiodo","year":"2000","journal-title":"West J Med"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215347449?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215347449?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T09:19:54Z","timestamp":1586251194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215347449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":53,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S0012369215347449"],"URL":"https:\/\/doi.org\/10.1378\/chest.127.5.1729","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}