{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:29:55Z","timestamp":1769167795407,"version":"3.49.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1378\/chest.128.4.2195","type":"journal-article","created":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T17:57:43Z","timestamp":1129744663000},"page":"2195-2202","source":"Crossref","is-referenced-by-count":15,"title":["Respiratory Dead Space Measurement in the Investigation of Pulmonary Embolism in Outpatients With Pleuritic Chest Pain"],"prefix":"10.1016","volume":"128","author":[{"given":"Kerstin","family":"Hogg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Dawson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ted","family":"Tabor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beverly","family":"Tabor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Mackway-Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1378\/chest.128.4.2195_bib1","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1001\/archinte.1997.00440360079008","article-title":"Deep vein thrombosis and pulmonary embolism in the general population: the study of men born in 1913","volume":"157","author":"Hansson","year":"1997","journal-title":"Arch Intern Med"},{"key":"10.1378\/chest.128.4.2195_bib2","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1164\/ajrccm.159.3.9806130","article-title":"Accuracy of clinical assessment in the diagnosis of pulmonary embolism","volume":"159","author":"Miniati","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.4.2195_bib3","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0002-9149(81)90388-X","article-title":"History and physical examination in acute pulmonary embolism in patients without preexisting cardiac or pulmonary disease","volume":"47","author":"Stein","year":"1981","journal-title":"Am J Cardiol"},{"key":"10.1378\/chest.128.4.2195_bib4","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1056\/NEJM195903192601204","article-title":"A physiologic approach to the diagnosis of pulmonary embolism","volume":"260","author":"Robin","year":"1959","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.128.4.2195_bib5","first-page":"679","article-title":"The dead space to tidal volume ratio in the diagnosis pulmonary embolism","volume":"133","author":"Burki","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.128.4.2195_bib6","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0196-0644(98)70004-6","article-title":"Preliminary study of the capnogram waveform area to screen for pulmonary embolism","volume":"32","author":"Kline","year":"1998","journal-title":"Ann Emerg Med"},{"key":"10.1378\/chest.128.4.2195_bib7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1378\/chest.96.2.357","article-title":"Diagnosis of pulmonary embolism based on alveolar dead space analysis","volume":"96","author":"Eriksson","year":"1989","journal-title":"Chest"},{"key":"10.1378\/chest.128.4.2195_bib8","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1001\/jama.285.6.761","article-title":"Diagnostic accuracy of a bedside d-dimer assay and alveolar dead-space measurement for rapid exclusion of pulmonary embolism: a multicenter study","volume":"285","author":"Kline","year":"2001","journal-title":"JAMA"},{"key":"10.1378\/chest.128.4.2195_bib9","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/j.1553-2712.1997.tb03809.x","article-title":"Use of the alveolar dead space fraction (Vd\/Vt) and plasma d-dimers to exclude acute pulmonary embolism in ambulatory patients","volume":"4","author":"Kline","year":"1997","journal-title":"Acad Emerg Med"},{"key":"10.1378\/chest.128.4.2195_bib10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1378\/chest.120.1.115","article-title":"Steady-state end-tidal alveolar dead space fraction and d-dimer: bedside tests to exclude pulmonary embolism","volume":"120","author":"Rodger","year":"2001","journal-title":"Chest"},{"key":"10.1378\/chest.128.4.2195_bib11","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1055\/s-0037-1613830","article-title":"Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED d-dimer","volume":"83","author":"Wells","year":"2000","journal-title":"Thromb Haemost"},{"key":"10.1378\/chest.128.4.2195_bib12","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2307\/2531595","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"De Long","year":"1988","journal-title":"Biometrics"},{"key":"10.1378\/chest.128.4.2195_bib13","first-page":"119","article-title":"Approximate is better than \u201cexact\u201d for interval estimation of binomial proportions","volume":"52","author":"Agresti","year":"1998","journal-title":"Am Stat"},{"key":"10.1378\/chest.128.4.2195_bib14","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1002\/(SICI)1097-0258(19980430)17:8<857::AID-SIM777>3.0.CO;2-E","article-title":"Two-sided confidence intervals for the single proportion: comparison of seven methods","volume":"17","author":"Newcombe","year":"1998","journal-title":"Stat Med"},{"key":"10.1378\/chest.128.4.2195_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2307\/2531848","article-title":"Approximate interval estimation of the ratio of binomial parameters: a review and corrections for skewness","volume":"44","author":"Gart","year":"1988","journal-title":"Biometrics"},{"key":"10.1378\/chest.128.4.2195_bib16","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1161\/01.CIR.33.1.146","article-title":"The main functions of the pulmonary circulation","volume":"33","author":"Comroe","year":"1966","journal-title":"Circulation"},{"key":"10.1378\/chest.128.4.2195_bib17","first-page":"281","article-title":"Ventilation\/perfusion scan and dead space in pulmonary embolism: are they useful for the diagnosis?","volume":"45","author":"Giuntini","year":"2001","journal-title":"Q J Nucl Med"},{"key":"10.1378\/chest.128.4.2195_bib18","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1378\/chest.112.4.974","article-title":"Clinical characteristics of patients with acute pulmonary embolism stratified according to their presenting syndromes","volume":"112","author":"Stein","year":"1997","journal-title":"Chest"},{"key":"10.1378\/chest.128.4.2195_bib19","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1378\/chest.125.3.841","article-title":"Volumetric capnography as a screening test for pulmonary embolism in the emergency department","volume":"125","author":"Verschuren","year":"2004","journal-title":"Chest"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215526226?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215526226?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T21:41:03Z","timestamp":1554154863000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215526226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S0012369215526226"],"URL":"https:\/\/doi.org\/10.1378\/chest.128.4.2195","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}