{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:17:02Z","timestamp":1791346622579,"version":"4.3.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1378\/chest.128.5.3336","type":"journal-article","created":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T18:52:49Z","timestamp":1132685569000},"page":"3336-3344","source":"Crossref","is-referenced-by-count":59,"title":["Factors Associated With Dyspnea in Adult Patients With Sickle Cell Disease"],"prefix":"10.1016","volume":"128","author":[{"given":"Christophe","family":"Delclaux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Zerah-Lancner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dora","family":"Bachir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoosha","family":"Habibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Monin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Godeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fre\u00edde\u00edric","family":"Galacteros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1378\/chest.128.5.3336_bib1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1136\/thx.26.3.309","article-title":"An assessment of lung volumes and gas transfer in sickle-cell anaemia.","volume":"26","author":"Miller","year":"1971","journal-title":"Thorax"},{"key":"10.1378\/chest.128.5.3336_bib2","first-page":"339","article-title":"Cardiorespiratory adjustments in chronic sickle cell anemia.","volume":"19","author":"Lonsdorfer","year":"1983","journal-title":"Bull Eur Physiopathol Respir"},{"key":"10.1378\/chest.128.5.3336_bib3","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1152\/jappl.1970.28.5.574","article-title":"Pulmonary function studies in sickle cell disease.","volume":"28","author":"Femi-Pearse","year":"1970","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.128.5.3336_bib4","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1183\/09031936.98.12051124","article-title":"Pulmonary function in sickle cell disease with or without acute chest syndrome.","volume":"12","author":"Santoli","year":"1998","journal-title":"Eur Respir J"},{"key":"10.1378\/chest.128.5.3336_bib5","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1172\/JCI103629","article-title":"A study of cardiopulmonary alterations in patients with sickle cell disease and its variants.","volume":"37","author":"Sproule","year":"1958","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.128.5.3336_bib6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1164\/ajrccm.165.3.2107017","article-title":"Increased nitric oxide output from alveolar origin during liver cirrhosis versus bronchial source during asthma.","volume":"165","author":"Delclaux","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.5.3336_bib7","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/ajh.10284","article-title":"Decreased exhaled nitric oxide in sickle cell disease: relationship with chronic lung involvement.","volume":"72","author":"Girgis","year":"2003","journal-title":"Am J Hematol"},{"key":"10.1378\/chest.128.5.3336_bib8","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1164\/ajrccm.152.3.7663792","volume":"152","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.5.3336_bib9","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1164\/ajrccm.152.6.8520796","volume":"152","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.5.3336_bib10","first-page":"325","article-title":"Lung function and exercise performance of healthy Caribbean men and women of African ethnic origin.","volume":"57","author":"Miller","year":"1972","journal-title":"Q J Exp Physiol Cogn Med Sci"},{"key":"10.1378\/chest.128.5.3336_bib11","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1152\/jappl.1957.11.2.290","article-title":"Relative importance of diffusion and chemical reaction rates in determining rate of the exchange of gases in human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries.","volume":"11","author":"Roughton","year":"1957","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.128.5.3336_bib12","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1042\/cs0420325","article-title":"Iron-deficiency anaemia: its effect on transfer factor for the lung (diffusing capacity) and ventilation and cardiac frequency during sub-maximal exercise.","volume":"42","author":"Cotes","year":"1972","journal-title":"Clin Sci"},{"key":"10.1378\/chest.128.5.3336_bib13","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1164\/ajrccm.160.6.ats8-99","volume":"160","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.5.3336_bib14","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1152\/jappl.1998.85.2.653","article-title":"A two-compartment model of pulmonary nitric oxide exchange dynamics.","volume":"85","author":"Tsoukias","year":"1998","journal-title":"J Appl Physiol"},{"key":"10.1378\/chest.128.5.3336_bib15","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1164\/ajrccm.159.1.ats898","volume":"159","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"18(suppl)","key":"10.1378\/chest.128.5.3336_bib16","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1093\/clinids\/18.Supplement_1.S79","article-title":"Measuring the functional impact of fatigue: initial validation of the fatigue impact scale.","author":"Fisk","year":"1994","journal-title":"Clin Infect Dis"},{"key":"10.1378\/chest.128.5.3336_bib17","first-page":"1139","article-title":"Fatigue scales used in multiple sclerosis.","volume":"158","author":"Debouverie","year":"2002","journal-title":"Rev Neurol (Paris)"},{"key":"10.1378\/chest.128.5.3336_bib18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1164\/ajrccm.166.1.at1102","volume":"166","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.5.3336_bib19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0894-7317(89)80014-8","article-title":"Recommendations for quantitation of the left ventricle by two-dimensional echocardiography: American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms.","volume":"2","author":"Schiller","year":"1989","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1378\/chest.128.5.3336_bib20","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1053\/hupa.2002.128059","article-title":"Pulmonary hypertension in sickle cell hemoglobinopathy: a clinicopathologic study of 20 cases.","volume":"33","author":"Haque","year":"2002","journal-title":"Hum Pathol"},{"key":"10.1378\/chest.128.5.3336_bib21","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1172\/JCI104362","article-title":"The effect of anemia on the alveolar-capillary exchange of carbon monoxide in man.","volume":"40","author":"Rankin","year":"1961","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.128.5.3336_bib22","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1056\/NEJMoa035477","article-title":"Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.","volume":"350","author":"Gladwin","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.128.5.3336_bib23","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/1043-4666(91)90497-2","article-title":"Altered cytokine release in peripheral blood mononuclear cell cultures from patients with the chronic fatigue syndrome.","volume":"3","author":"Chao","year":"1991","journal-title":"Cytokine"},{"key":"10.1378\/chest.128.5.3336_bib24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/(SICI)1096-8652(199902)60:2<105::AID-AJH4>3.0.CO;2-Z","article-title":"Circulating cytokines response and the level of erythropoiesis in sickle cell anemia.","volume":"60","author":"Croizat","year":"1999","journal-title":"Am J Hematol"},{"key":"10.1378\/chest.128.5.3336_bib25","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1001\/archinte.1987.00370070045007","article-title":"The painful crisis of homozygous sickle cell disease: a study of the risk factors.","volume":"147","author":"Baum","year":"1987","journal-title":"Arch Intern Med"},{"key":"10.1378\/chest.128.5.3336_bib26","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1161\/01.CIR.0000044943.12533.A8","article-title":"Divergent nitric oxide bioavailability in men and women with sickle cell disease.","volume":"107","author":"Gladwin","year":"2003","journal-title":"Circulation"},{"key":"10.1378\/chest.128.5.3336_bib27","doi-asserted-by":"crossref","first-page":"11259","DOI":"10.1073\/pnas.89.23.11259","article-title":"Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.","volume":"89","author":"Hayashi","year":"1992","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1378\/chest.128.5.3336_bib28","doi-asserted-by":"crossref","first-page":"5212","DOI":"10.1073\/pnas.91.11.5212","article-title":"Induction of calcium-dependent nitric oxide synthases by sex hormones.","volume":"91","author":"Weiner","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1378\/chest.128.5.3336_bib29","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1164\/ajrccm.158.5.9710086","article-title":"Reference equations for the six-minute walk in healthy adults.","volume":"158","author":"Enright","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.5.3336_bib30","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1164\/rccm.2002036","article-title":"Cardiopulmonary responses to exercise in women with sickle cell anemia.","volume":"165","author":"Callahan","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1378\/chest.128.5.3336_bib31","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1164\/ajrccm\/143.2.226","article-title":"Ventilation and gas exchange during exercise in sickle cell anemia.","volume":"143","author":"Pianosi","year":"1991","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.128.5.3336_bib32","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/00043426-200308000-00008","article-title":"Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease.","volume":"25","author":"Morris","year":"2003","journal-title":"J Pediatr Hematol Oncol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215528985?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215528985?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T09:54:27Z","timestamp":1531130067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215528985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0012369215528985"],"URL":"https:\/\/doi.org\/10.1378\/chest.128.5.3336","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}