{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T03:24:19Z","timestamp":1785295459117,"version":"3.55.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:00:00Z","timestamp":1455840000000},"content-version":"vor","delay-in-days":628,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1378\/chest.13-1371","type":"journal-article","created":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T09:46:16Z","timestamp":1382607976000},"page":"1213-1218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"title":["Do Grandmaternal Smoking Patterns Influence the Etiology of Childhood Asthma?"],"prefix":"10.1016","volume":"145","author":[{"given":"Laura L.","family":"Miller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Northstone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Pembrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Golding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1378\/chest.13-1371_bib1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1136\/thx.2006.066407","article-title":"50 years of asthma: UK trends from 1955 to 2004","volume":"62","author":"Anderson","year":"2007","journal-title":"Thorax"},{"key":"10.1378\/chest.13-1371_bib2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1146\/annurev.publhealth.031308.100151","article-title":"Gene by environment interaction in asthma","volume":"30","author":"London","year":"2009","journal-title":"Annu Rev Public Health"},{"issue":"3","key":"10.1378\/chest.13-1371_bib3","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1513\/pats.200701-031AW","article-title":"Gene-air pollution interactions in asthma","volume":"4","author":"London","year":"2007","journal-title":"Proc Am Thorac Soc"},{"issue":"3","key":"10.1378\/chest.13-1371_bib4","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1378\/chest.10-1800","article-title":"Epigenetics and prenatal influences on asthma and allergic airways disease","volume":"139","author":"Martino","year":"2011","journal-title":"Chest"},{"issue":"3","key":"10.1378\/chest.13-1371_bib5","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.jaci.2010.07.030","article-title":"Environmental epigenetics of asthma: an update","volume":"126","author":"Ho","year":"2010","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1378\/chest.13-1371_bib6","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1136\/thx.2009.120154","article-title":"Maternal smoking during pregnancy decreases Wnt signalling in neonatal mice","volume":"65","author":"Blacqui\u00e8re","year":"2010","journal-title":"Thorax"},{"issue":"8","key":"10.1378\/chest.13-1371_bib7","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1513\/pats.200907-065DP","article-title":"Intrauterine effects of maternal smoking on sensitization, asthma, and chronic obstructive pulmonary disease","volume":"6","author":"Hylkema","year":"2009","journal-title":"Proc Am Thorac Soc"},{"issue":"1","key":"10.1378\/chest.13-1371_bib8","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/ppul.22783","article-title":"The effect of grand maternal nicotine exposure during gestation and lactation on lung integrity of the F2 generation","volume":"49","author":"Maritz","year":"2014","journal-title":"Pediatr Pulmonol"},{"key":"10.1378\/chest.13-1371_bib9","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/1741-7015-10-129","article-title":"Perinatal nicotine exposure induces asthma in second generation offspring","volume":"10","author":"Rehan","year":"2012","journal-title":"BMC Med"},{"issue":"5","key":"10.1378\/chest.13-1371_bib10","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1164\/rccm.200901-0135OC","article-title":"Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation","volume":"180","author":"Breton","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1378\/chest.13-1371_bib11","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.gene.2011.11.062","article-title":"Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke","volume":"494","author":"Murphy","year":"2012","journal-title":"Gene"},{"issue":"10","key":"10.1378\/chest.13-1371_bib12","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1289\/ehp.1205412","article-title":"450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy","volume":"120","author":"Joubert","year":"2012","journal-title":"Environ Health Perspect"},{"issue":"4","key":"10.1378\/chest.13-1371_bib13","first-page":"1232","article-title":"Maternal and grandmaternal smoking patterns are associated with early childhood asthma","volume":"127","author":"Li","year":"2005","journal-title":"Chest"},{"issue":"2","key":"10.1378\/chest.13-1371_bib14","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1046\/j.1365-3016.2000.00247.x","article-title":"Maternal smoking affects fetal growth more in the male fetus","volume":"14","author":"Zar\u00e9n","year":"2000","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"1","key":"10.1378\/chest.13-1371_bib15","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1046\/j.1365-3016.2001.00325.x","article-title":"ALSPAC\u2014the Avon Longitudinal Study of Parents and Children. I. Study methodology","volume":"15","author":"Golding","year":"2001","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"1","key":"10.1378\/chest.13-1371_bib16","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/ije\/dys064","article-title":"Cohort Profile: the \u2018children of the 90s\u2019\u2014the index offspring of the Avon Longitudinal Study of Parents and Children","volume":"42","author":"Boyd","year":"2013","journal-title":"Int J Epidemiol"},{"issue":"4","key":"10.1378\/chest.13-1371_bib17","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1542\/peds.2011-2196","article-title":"Prenatal and passive smoke exposure and incidence of asthma and wheeze: systematic review and meta-analysis","volume":"129","author":"Burke","year":"2012","journal-title":"Pediatrics"},{"issue":"6","key":"10.1378\/chest.13-1371_bib18","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1093\/ije\/30.6.1473","article-title":"Risk factor associations with wheezing patterns in children followed longitudinally from birth to 3(1\/2) years","volume":"30","author":"Sherriff","year":"2001","journal-title":"Int J Epidemiol"},{"issue":"3","key":"10.1378\/chest.13-1371_bib19","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1164\/ajrccm.152.3.7663792","article-title":"Standardization of spirometry: 1994 update","volume":"152","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"10.1378\/chest.13-1371_bib20","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1136\/thx.47.9.707","article-title":"Height and age adjustment for cross sectional studies of lung function in children aged 6-11 years","volume":"47","author":"Chinn","year":"1992","journal-title":"Thorax"},{"issue":"10","key":"10.1378\/chest.13-1371_bib21","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1136\/thx.38.10.760","article-title":"Rapid method for measurement of bronchial responsiveness","volume":"38","author":"Yan","year":"1983","journal-title":"Thorax"},{"issue":"9","key":"10.1378\/chest.13-1371_bib22","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.2105\/AJPH.89.9.1377","article-title":"Prenatal effects of maternal smoking on daughters' smoking: nicotine or testosterone exposure?","volume":"89","author":"Kandel","year":"1999","journal-title":"Am J Public Health"},{"issue":"2","key":"10.1378\/chest.13-1371_bib23","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000299009","article-title":"Smoking in pregnancy: the influence on percentile birth weight, mean birth weight, placental weight, menstrual age, perinatal mortality and maternal diastolic blood pressure","volume":"19","author":"van der Velde","year":"1985","journal-title":"Gynecol Obstet Invest"},{"issue":"7","key":"10.1378\/chest.13-1371_bib24","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/aje\/152.7.658","article-title":"Family history, maternal smoking, and clubfoot: an indication of a gene-environment interaction","volume":"152","author":"Honein","year":"2000","journal-title":"Am J Epidemiol"},{"issue":"3","key":"10.1378\/chest.13-1371_bib25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/tera.1420350305","article-title":"Maternal smoking: greater effect on males, fetal tobacco syndrome?","volume":"35","author":"Wertelecki","year":"1987","journal-title":"Teratology"},{"issue":"3","key":"10.1378\/chest.13-1371_bib26","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0091-3057(85)90018-8","article-title":"Prenatal nicotine affects fetal testosterone and sexual dimorphism of saccharin preference","volume":"23","author":"Lichtensteiger","year":"1985","journal-title":"Pharmacol Biochem Behav"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215347929?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215347929?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T06:50:15Z","timestamp":1757919015000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215347929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S0012369215347929"],"URL":"https:\/\/doi.org\/10.1378\/chest.13-1371","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Do Grandmaternal Smoking Patterns Influence the Etiology of Childhood Asthma?","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1378\/chest.13-1371","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1378\/chest.13-2868","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The American College of Chest Physicians. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}