{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:30:08Z","timestamp":1760027408133},"reference-count":20,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1977,5,1]],"date-time":"1977-05-01T00:00:00Z","timestamp":231292800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[1977,5]]},"DOI":"10.1378\/chest.71.5.592","type":"journal-article","created":{"date-parts":[[2007,11,7]],"date-time":"2007-11-07T17:53:57Z","timestamp":1194458037000},"page":"592-596","source":"Crossref","is-referenced-by-count":44,"title":["Beta-Adrenergic Blockade as Adjunctive Oral Therapy in Patients with Chronic Atrial Fibrillation"],"prefix":"10.1016","volume":"71","author":[{"given":"Joachim","family":"Yahalom","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herman O.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elieser","family":"Kaplinsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1378\/chest.71.5.592_bib1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1161\/01.CIR.47.2.399","article-title":"Hemodynamic sequelae of cardiac arrhythmias","volume":"47","author":"Samet","year":"1973","journal-title":"Circulation"},{"key":"10.1378\/chest.71.5.592_bib2","first-page":"49","article-title":"The reaction to exercise of the heart affected by auricular fibrillation","volume":"11","author":"Blumgart","year":"1924","journal-title":"Heart"},{"key":"10.1378\/chest.71.5.592_bib3","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1136\/bmj.3.5720.429","article-title":"Plasma digoxin concentration in patients with atrial fibrillation","volume":"3","author":"Chamberlain","year":"1970","journal-title":"Br Med J"},{"key":"10.1378\/chest.71.5.592_bib4","first-page":"114","article-title":"Digoxin: How effective for heart rate control in ambulatory patients with atrial fibrillation?","volume":"46","author":"Belic","year":"1972","journal-title":"Circulation"},{"key":"10.1378\/chest.71.5.592_bib5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.0954-6820.1971.tb07437.x","article-title":"Digoxin dosage and ventricular rate at rest and exercise in patients with atrial fibrillation","volume":"190","author":"Redfords","year":"1971","journal-title":"Acta Med Scand"},{"key":"10.1378\/chest.71.5.592_bib6","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/0002-9149(75)90051-X","article-title":"Inefficacy of \u201ctherapeutic\u201d serum levels of digoxin in controlling the ventricular rate in atrial fibrillation","volume":"35","author":"Goldman","year":"1975","journal-title":"Am J Cardiol"},{"key":"10.1378\/chest.71.5.592_bib7","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/0033-0620(69)90033-4","article-title":"The use of beta-adrenergic receptor blocking drugs in dysrhythmias","volume":"12","author":"Gibson","year":"1969","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1378\/chest.71.5.592_bib8","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/0002-9149(75)90050-8","article-title":"The use of practolol in supraventricular arrhythmias associated with acute illnesses","volume":"35","author":"Pribble","year":"1975","journal-title":"Am J Cardiol"},{"key":"10.1378\/chest.71.5.592_bib9","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1056\/NEJM197508072930606","article-title":"Drug therapy: Propranolol","volume":"293","author":"Shand","year":"1975","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.71.5.592_bib10","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0002-9149(66)90071-3","article-title":"Unwanted effects of propranolol","volume":"18","author":"Stephen","year":"1966","journal-title":"Am J Cardiol"},{"key":"10.1378\/chest.71.5.592_bib11","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0002-9149(72)90525-5","article-title":"Circulatory effects of practolol","volume":"29","author":"Finegan","year":"1972","journal-title":"Am J Cardiol"},{"key":"10.1378\/chest.71.5.592_bib12","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1002\/cpt1969106765","article-title":"Clinical pharmacology of beta receptor blocking drugs","volume":"10","author":"Dollery","year":"1969","journal-title":"Clin Pharmacol Ther"},{"key":"10.1378\/chest.71.5.592_bib13","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1161\/01.CIR.51.2.394","article-title":"First and second versus second and third exercise test","volume":"51","author":"Spodick","year":"1975","journal-title":"Circulation"},{"key":"10.1378\/chest.71.5.592_bib14","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/0002-8703(75)90043-5","article-title":"Immediate cardiac response to exercise: Physiologic investigation by systolic time intervals at graded work loads","volume":"89","author":"Xenakis","year":"1975","journal-title":"Am Heart J"},{"key":"10.1378\/chest.71.5.592_bib15","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1378\/chest.64.5.619","article-title":"Comparison of relative inotropic and chronotropic effects of propranolol, practolol and sotalol","volume":"64","author":"Goldstein","year":"1973","journal-title":"Chest"},{"key":"10.1378\/chest.71.5.592_bib16","first-page":"573","article-title":"Blood levels of practolol following intravenous administration","volume":"40","author":"Aellig","year":"1970","journal-title":"Br J Pharmacol"},{"key":"10.1378\/chest.71.5.592_bib17","first-page":"467","article-title":"Effect of a new beta-blocking agent (ICI 50, 1972) on heart rate in relation to its blood levels","volume":"1","author":"Fitzgerald","year":"1968","journal-title":"Int Z Klin Pharmakol Ther Toxikol"},{"key":"10.1378\/chest.71.5.592_bib18","first-page":"228","article-title":"Digitalis blood levels and toxicity (letter to editor)","volume":"295","author":"G\u00fcllner","year":"1976","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.71.5.592_bib19","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1136\/bmj.2.5918.560","article-title":"Skin reaction to practolol","volume":"2","author":"Wright","year":"1974","journal-title":"Br Med J"},{"key":"10.1378\/chest.71.5.592_bib20","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/S0140-6736(74)90218-9","article-title":"Sclerosing peritonitis: An unusual reaction to beta adrenergic blocking drug (practolol)","volume":"2","author":"Brown","year":"1974","journal-title":"Lancet"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216405441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216405441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T05:21:37Z","timestamp":1546492897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369216405441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,5]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1977,5]]}},"alternative-id":["S0012369216405441"],"URL":"https:\/\/doi.org\/10.1378\/chest.71.5.592","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[1977,5]]}}}