{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T06:35:01Z","timestamp":1770273301844,"version":"3.49.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1978,2,1]],"date-time":"1978-02-01T00:00:00Z","timestamp":255139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[1978,2]]},"DOI":"10.1378\/chest.73.2.202","type":"journal-article","created":{"date-parts":[[2007,11,7]],"date-time":"2007-11-07T17:53:57Z","timestamp":1194458037000},"page":"202-206","source":"Crossref","is-referenced-by-count":30,"title":["Therapeutic Properties of Oral Ambruticin (W7783) in Experimental Pulmonary Coccidioidomycosis of Mice"],"prefix":"10.1016","volume":"73","author":[{"given":"H.B.","family":"Levine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.M.","family":"Ringel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Cobb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1378\/chest.73.2.202_bib1","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1056\/NEJM197401032900107","article-title":"Drug therapy: Chemotherapy of systemic mycoses","volume":"290","author":"Bennett","year":"1974","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.73.2.202_bib2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0002-9343(76)90428-9","article-title":"Miconazole in coccidioidomycosis: 2 Therapeutic and pharmacologic studies in man","volume":"60","author":"Stevens","year":"1976","journal-title":"Am J Med"},{"key":"10.1378\/chest.73.2.202_bib3","first-page":"5","article-title":"Intravenous and intrathecal miconazole therapy for systemic mycoses","volume":"126","author":"Sung","year":"1977","journal-title":"West J Med"},{"key":"10.1378\/chest.73.2.202_bib4","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1378\/chest.70.6.755","article-title":"R34000, a dioxolane imidazole in the therapy of experimental coccidioidomycosis: Comparison with miconazole and econazole","volume":"70","author":"Levine","year":"1976","journal-title":"Chest"},{"key":"10.1378\/chest.73.2.202_bib5","doi-asserted-by":"crossref","first-page":"340","DOI":"10.7326\/0003-4819-61-2-340","article-title":"Amphotericin B toxicity: Combined clinical staff conference at the National Institutes of Health: General side effects","volume":"61","author":"Utz","year":"1964","journal-title":"Ann Intern Med"},{"key":"10.1378\/chest.73.2.202_bib6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/00362177085190301","article-title":"Annulment of amphotericin B inhibition of Coccidioides immitis endospores: Effects on growth, respiration and morphogenesis","volume":"7","author":"Sippel","year":"1969","journal-title":"Sabouraudia"},{"key":"10.1378\/chest.73.2.202_bib7","article-title":"Coccidioidomycosis: Current clinical and diagnostic status. Proceedings of the Third International Coccidioidomycosis Symposium, American College of Chest Physicians","author":"Ajello","year":"1977","journal-title":"Miami, Symposia Specialists"},{"key":"10.1378\/chest.73.2.202_bib8","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1128\/AAC.9.3.406","article-title":"Effect of amphotericin B and rifampin against Coccidioides immitis in vivo and in vitro","volume":"9","author":"Huppert","year":"1976","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1378\/chest.73.2.202_bib9","doi-asserted-by":"crossref","first-page":"371","DOI":"10.7164\/antibiotics.30.371","article-title":"Ambruticin (W7783), a new antifungal antibiotic","volume":"30","author":"Ringel","year":"1977","journal-title":"J Antibiot"},{"key":"10.1378\/chest.73.2.202_bib10","author":"Levine","year":"1977","journal-title":"Miami, Symposia Specialists"},{"key":"10.1378\/chest.73.2.202_bib11","first-page":"198","article-title":"The virulence and infectivity of 27 strains of Coccidioides immitis","volume":"64","author":"Friedman","year":"1956","journal-title":"Am J Hyg"},{"key":"10.1378\/chest.73.2.202_bib12","article-title":"Coccidioidomycosis","author":"Fiese","year":"1958","journal-title":"Springfield, Ill, Charles C Thomas"},{"key":"10.1378\/chest.73.2.202_bib13","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1080\/00362177085190051","article-title":"Spherule coccidioidin in delayed dermal sensitivity reactions of experimental animals","volume":"7","author":"Levine","year":"1969","journal-title":"Sabouraudia"},{"key":"10.1378\/chest.73.2.202_bib14","first-page":"1","article-title":"The theory of antibiotic inhibition zones In Kavanaugh F (ed): Analytical Microbiology","author":"Cooper","year":"1963","journal-title":"New York, Academic Press, Inc"},{"key":"10.1378\/chest.73.2.202_bib15","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/infdis\/132.4.407","article-title":"Miconazole in coccidioidomycosis: 1 Assays of activity in mice and in vitro","volume":"132","author":"Levine","year":"1975","journal-title":"J Infect Dis"},{"key":"10.1378\/chest.73.2.202_bib16","article-title":"Ambruticin (W7783), a new class of antifungal antibiotics: in vitro and in vivo studies","volume":"152","author":"Ringel","year":"1977","journal-title":"17th Interscience Conference on Antimicrobial agents and Chemotherapy, (Abstr)"},{"key":"10.1378\/chest.73.2.202_bib17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1146\/annurev.mi.20.100166.000451","article-title":"Biology of the myxobacteria","volume":"20","author":"Dworkin","year":"1966","journal-title":"Ann Rev Microbiol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216386767?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216386767?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T05:51:08Z","timestamp":1546494668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369216386767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1978,2]]}},"alternative-id":["S0012369216386767"],"URL":"https:\/\/doi.org\/10.1378\/chest.73.2.202","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[1978,2]]}}}