{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T19:00:04Z","timestamp":1778698804106,"version":"3.51.4"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1985,3,1]],"date-time":"1985-03-01T00:00:00Z","timestamp":478483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[1985,3]]},"DOI":"10.1378\/chest.87.3.351","type":"journal-article","created":{"date-parts":[[2007,11,7]],"date-time":"2007-11-07T18:25:26Z","timestamp":1194459926000},"page":"351-355","source":"Crossref","is-referenced-by-count":58,"title":["Carcinomatous and Tuberculous Pleural Effusions"],"prefix":"10.1016","volume":"87","author":[{"given":"Yoshioki","family":"Niwa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotsugu","family":"Kishimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaoru","family":"Shimokata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1378\/chest.87.3.351_bib1","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1001\/archinte.1977.03630190035011","article-title":"Carcinoembryonic antigen titers on effusion fluid","volume":"137","author":"Nystrom","year":"1977","journal-title":"Arch Intern Med"},{"key":"10.1378\/chest.87.3.351_bib2","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1136\/bmj.2.6154.1751-a","article-title":"Adenosine deaminase activity in pleural effusions: an aid to differential diagnosis","volume":"2","author":"Piras","year":"1978","journal-title":"Br Med J"},{"key":"10.1378\/chest.87.3.351_bib3","first-page":"3244","article-title":"Isolation and characterization of an immunosuppressive acidic protein from ascitic fluids of cancer patients","volume":"41","author":"Tamura","year":"1981","journal-title":"Cancer Res"},{"key":"10.1378\/chest.87.3.351_bib4","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1007\/BF01542654","article-title":"Colorectal carcinoma antigens detected by hybridoma antibodies","volume":"5","author":"Koprowski","year":"1979","journal-title":"Somat Cell Genet"},{"key":"10.1378\/chest.87.3.351_bib5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1126\/science.7209516","article-title":"A monosialoganglioside is a monoclonal antibody-defined antigen of colon carcinoma","volume":"212","author":"Magnani","year":"1981","journal-title":"Science"},{"key":"10.1378\/chest.87.3.351_bib6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1159\/000401148","article-title":"Tissue polypeptide antigen (TPA): biology, biochemistry, improved assay methodology, clinical significance in cancer and other conditions, and future outlook","volume":"22","author":"Bj\u00f4rklund","year":"1978","journal-title":"Antibiot Chemother"},{"key":"10.1378\/chest.87.3.351_bib7","first-page":"269","article-title":"The carbohydrate antigenic determinant 19-9 (CA 19-9): a monoclonal antibody defined tumor marker","volume":"8","author":"DelVillano","year":"1983","journal-title":"Lab Res Methods Biol Med"},{"key":"10.1378\/chest.87.3.351_bib8","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1093\/clinchem\/24.6.868","article-title":"A preliminary evaluation of tissue polypeptide antigen in serum or urine (or both) of patients with cancer or benign neoplasms","volume":"24","author":"Menendez-Botet","year":"1978","journal-title":"Clin Chem"},{"key":"10.1378\/chest.87.3.351_bib9","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0019-2791(65)90004-2","article-title":"Immunochemical quantitation of antigens by single radial immunodiffusion","volume":"2","author":"Mancini","year":"1965","journal-title":"Immunochemistry"},{"key":"10.1378\/chest.87.3.351_bib10","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/clinchem\/29.3.549","article-title":"Radioimmunometric assay for a monoclonal antibody-defined tumor marker, CA 19-9","volume":"29","author":"DelVillano","year":"1983","journal-title":"Clin Chem"},{"key":"10.1378\/chest.87.3.351_bib11","first-page":"78","article-title":"Radioimmunoassay of TPA a laboratory test in cancer","volume":"2","author":"Bjorklund","year":"1980","journal-title":"Tumor Diagnostik"},{"key":"10.1378\/chest.87.3.351_bib12","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1002\/1097-0142(19821101)50:9<1783::AID-CNCR2820500923>3.0.CO;2-V","article-title":"Diagnostic value of tumoral markers in serous effusions carcinoembryonic antigen, alpha1-acidglycoprotein, alpha-fetoprotein, phosphohexose isomerase, and beta2-microglobulin","volume":"50","author":"Martinez-Vea","year":"1982","journal-title":"Cancer"},{"key":"10.1378\/chest.87.3.351_bib13","first-page":"35","article-title":"Measurement of adenosine deaminase (ADA) activity in pleural effusion with special reference to carcinomatous and tuberculous pleuritis","volume":"19","author":"Hayashi","year":"1981","journal-title":"Jap J Thorac Dis"},{"key":"10.1378\/chest.87.3.351_bib14","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1093\/ajcp\/76.4.437","article-title":"Orosomucoid, a2-macroglobulin and immunoglobulins in serum and pleural effusions","volume":"76","author":"Asseo","year":"1981","journal-title":"Am J Clin Pathol"},{"key":"10.1378\/chest.87.3.351_bib15","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1172\/JCI107736","article-title":"Orosomucoid content of pleural and peritoneal effusions","volume":"54","author":"Rudman","year":"1974","journal-title":"J Clin Invest"},{"key":"10.1378\/chest.87.3.351_bib16","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/ajcp\/67.2.146","article-title":"Orosomucoid contents of pleural and peritoneal effusions of various etiologies","volume":"67","author":"Agostoni","year":"1977","journal-title":"Am J Clin Pathol"},{"key":"10.1378\/chest.87.3.351_bib17","first-page":"3365","article-title":"Immunosuppressive activity and tissue polypeptide antigen content of human ascitic fluids","volume":"38","author":"Badger","year":"1978","journal-title":"Cancer Res"},{"key":"10.1378\/chest.87.3.351_bib18","doi-asserted-by":"crossref","first-page":"631","DOI":"10.7326\/0003-4819-88-5-631","article-title":"Carcinoembryonic antigen levels in benign and malignant pleural effusions","volume":"88","author":"Rittgers","year":"1978","journal-title":"Ann Intern Med"},{"key":"10.1378\/chest.87.3.351_bib19","doi-asserted-by":"crossref","first-page":"424","DOI":"10.7326\/0003-4819-89-3-424_1","article-title":"Carcinoembryonic antigen assay","volume":"89","author":"Haas","year":"1978","journal-title":"Ann Intern Med"},{"key":"10.1378\/chest.87.3.351_bib20","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/S0140-6736(78)92391-7","article-title":"Carcinoembryonic antigen in pleural effusions","volume":"2","author":"Klockars","year":"1978","journal-title":"Lancet"},{"key":"10.1378\/chest.87.3.351_bib21","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1378\/chest.79.3.297","article-title":"Differential diagnosis of pleural effusions: clinical usefulness of cell marker quantitation","volume":"79","author":"Vladutiu","year":"1981","journal-title":"Chest"},{"key":"10.1378\/chest.87.3.351_bib22","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1002\/1097-0142(19811201)48:11<2475::AID-CNCR2820481121>3.0.CO;2-Y","article-title":"Combined effusion fluid tumor marker assay, carcinoembryonic antigen (CEA) and human chorionic gonadotropin (hCG), in the detection of malignant tumors","volume":"48","author":"Couch","year":"1981","journal-title":"Cancer"},{"key":"10.1378\/chest.87.3.351_bib23","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1073\/pnas.69.9.2492","article-title":"Burtin P Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen","volume":"69","author":"von Kleist","year":"1972","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1378\/chest.87.3.351_bib24","first-page":"203","article-title":"Presence of antigen related to the carcinoembryonic antigen in feces of normal adults","volume":"64","author":"Matsuoka","year":"1973","journal-title":"Gann"},{"key":"10.1378\/chest.87.3.351_bib25","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(78)91371-5","article-title":"Concurrent assays of plasma and pleural-effusion levels of carcinoembryonic antigen in the diagnosis of pulmonary disease","volume":"2","author":"Stanford","year":"1978","journal-title":"Lancet"},{"key":"10.1378\/chest.87.3.351_bib26","first-page":"556","article-title":"Adenosine deaminase estimations in the differentiation of pleural effusions","volume":"62","author":"Maritz","year":"1982","journal-title":"S Afr Med J"},{"key":"10.1378\/chest.87.3.351_bib27","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1378\/chest.84.1.51","article-title":"Adenosine deaminase in pleural fluids test for diagnosis of tuberculous pleural effusion","volume":"84","author":"Ocana","year":"1983","journal-title":"Chest"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215408554?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215408554?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T23:16:06Z","timestamp":1588029366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215408554"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,3]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1985,3]]}},"alternative-id":["S0012369215408554"],"URL":"https:\/\/doi.org\/10.1378\/chest.87.3.351","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[1985,3]]}}}