{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:00:29Z","timestamp":1788577229732,"version":"build-2803163510"},"reference-count":12,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1989,7,1]],"date-time":"1989-07-01T00:00:00Z","timestamp":615254400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chest"],"published-print":{"date-parts":[[1989,7]]},"DOI":"10.1378\/chest.96.1.114","type":"journal-article","created":{"date-parts":[[2007,11,7]],"date-time":"2007-11-07T18:25:26Z","timestamp":1194459926000},"page":"114-119","source":"Crossref","is-referenced-by-count":230,"title":["Randomized Double-Blind, Multicenter Study of Prostaglandin E1 in Patients with the Adult Respiratory Distress Syndrome"],"prefix":"10.1016","volume":"96","author":[{"given":"Roger C.","family":"Bone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gus","family":"Slotman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Maunder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Silverman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Hyers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morris D.","family":"Kerstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.","family":"Ursprung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1378\/chest.96.1.114_bib1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0025-7125(16)31197-X","article-title":"The adult respiratory distress syndrome.","volume":"67","author":"Balk","year":"1987","journal-title":"Med Clin N Am"},{"key":"10.1378\/chest.96.1.114_bib2","first-page":"472","article-title":"Adult respiratory distress syndrome: prognosis after onset.","volume":"132","author":"Fowler","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.96.1.114_bib3","first-page":"1071","article-title":"Mechanisms of acute respiratory failure.","volume":"115","author":"Murray","year":"1977","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.96.1.114_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0272-5231(21)00140-4","article-title":"Adult respiratory distress syndrome: definition and historical perspective.","volume":"3","author":"Petty","year":"1982","journal-title":"Clin Chest Med"},{"key":"10.1378\/chest.96.1.114_bib5","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1056\/NEJM197210052871404","article-title":"Acute respiratory failure in the adult (first of three parts).","volume":"287","author":"Pontoppidan","year":"1972","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.96.1.114_bib6","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/00000658-198604000-00006","article-title":"Prostaglandin E1 and survival in patients with the adult respiratory distress syndrome: A prospective trial.","volume":"203","author":"Holcroft","year":"1986","journal-title":"Ann Surg"},{"key":"10.1378\/chest.96.1.114_bib7","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1378\/chest.92.6.1032","article-title":"Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome.","volume":"92","author":"Bone","year":"1987","journal-title":"Chest"},{"key":"10.1378\/chest.96.1.114_bib8","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1056\/NEJM198712173172504","article-title":"High-dose corticosteroids in patients with the adult respiratory distress syndrome.","volume":"317","author":"Bernard","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1378\/chest.96.1.114_bib9","first-page":"273","article-title":"Effects of prostaglandin E1 in adult respiratory distress syndrome.","volume":"99","author":"Shoemaker","year":"1986","journal-title":"Surgery"},{"key":"10.1378\/chest.96.1.114_bib10","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/BF00254775","article-title":"The acute effects of prostaglandin E1 on the pulmonary circulation and oxygen delivery in patients with the adult respiratory distress syndrome.","volume":"11","author":"Tokioka","year":"1985","journal-title":"Intern Care Med"},{"key":"10.1378\/chest.96.1.114_bib11","first-page":"A281","article-title":"Acute effects of prostaglandin E1 on hemodynamics and oxygen delivery in adult respiratory distress syndrome.","volume":"133","author":"Dodek","year":"1986","journal-title":"Am Rev Respir Dis"},{"key":"10.1378\/chest.96.1.114_bib12","unstructured":"LS Zuckerman TD Friehling RA Marinchack Abstract. The American Heart Association Meeting Nov, 17-20, 1986 Dallas, TX"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215457526?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369215457526?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T03:24:46Z","timestamp":1630034686000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369215457526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,7]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1989,7]]}},"alternative-id":["S0012369215457526"],"URL":"https:\/\/doi.org\/10.1378\/chest.96.1.114","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[1989,7]]}}}