{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:14:54Z","timestamp":1771654494967,"version":"3.50.1"},"reference-count":25,"publisher":"Veterinary World","issue":"3","license":[{"start":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T00:00:00Z","timestamp":1553126400000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T00:00:00Z","timestamp":1553126400000},"content-version":"am","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T00:00:00Z","timestamp":1553126400000},"content-version":"tdm","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003285","name":"Ministerio de Salud de la Naci\u00f3n","doi-asserted-by":"publisher","award":["PNSA-1115057 INTA"],"award-info":[{"award-number":["PNSA-1115057 INTA"]}],"id":[{"id":"10.13039\/501100003285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet World"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>Background: Pasteurella multocida (Pm) is the causative agent of progressive atrophic rhinitis (PAR) and pneumonic pasteurellosis (PN) in pigs. Pm is a member of the porcine respiratory complex responsible for important economic loss in the pig industry. Aim: This study aimed to characterize the Pm strains recovered from clinical cases of PN and PAR and to elucidate the antibiotic susceptibility profiles of the strains. Materials and Methods: Sixty strains were characterized molecularly by polymerase chain reaction to determine species-specific gene, capsular type (A or D), and toxin A production. The agar diffusion method was employed to evaluate antibiotic resistance profiles. Results: We found that 65% of strains belonged to capsular type A or D, and 15% of those were positive to toxA gene. The antibiotic susceptibility profiles found were sensitive in decreasing order to: Enrofloxacin, ceftiofur (CTF), ampicillin, tilmicosin (TIL), florfenicol (FFN), spectinomycin (SPC), gentamicin, oxytetracycline (OTC), and trimethoprim-sulfamethoxazole (TMS). Strains were resistant in decreasing order to: Lincomycin (LIN), tylosin (TYL), erythromycin (ERY), TMS, SPC, OTC, FFN, TIL, and CTF. Conclusion: The toxA gene was detected in many Pm isolates from pneumonic lungs. Capsule type A or D was the most frequently found among the collected isolates. LIN, TYL, and ERY are the drugs which showed higher percentages of resistant isolates.<\/jats:p>","DOI":"10.14202\/vetworld.2019.434-439","type":"journal-article","created":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T13:39:07Z","timestamp":1553175547000},"page":"434-439","source":"Crossref","is-referenced-by-count":5,"title":["Characterization and comparison of strains of Pasteurella multocida associated with cases of progressive atrophic rhinitis and porcine pneumonia in Argentina"],"prefix":"10.14202","volume":"12","author":[{"given":"Fernando A.","family":"Bessone","sequence":"first","affiliation":[{"name":"Department of Animal Health, Instituto Nacional de Tecnologia Agropecuaria, Estacion Experimental Agropecuaria Marcos Juarez, Marcos Juarez, Cordoba, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Laura Soriano","family":"Perez","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Instituto Nacional de Tecnologia Agropecuaria, Estacion Experimental Agropecuaria Marcos Juarez, Marcos Juarez, Cordoba, Argentina; CONICET, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Zielinski","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Instituto Nacional de Tecnologia Agropecuaria, Estacion Experimental Agropecuaria Marcos Juarez, Marcos Juarez, Cordoba, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Dibarbora","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Instituto Nacional de Tecnologia Agropecuaria, Estacion Experimental Agropecuaria Marcos Juarez, Marcos Juarez, Cordoba, Argentina; CONICET, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. B.","family":"Conde","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Instituto Nacional de Tecnologia Agropecuaria, Estacion Experimental Agropecuaria Marcos Juarez, Marcos Juarez, Cordoba, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Cappuccio","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Instituto Nacional de Tecnologia Agropecuaria, Estacion Experimental Agropecuaria Marcos Juarez, Marcos Juarez, Cordoba, Argentina; CONICET, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrisio","family":"Alustiza","sequence":"additional","affiliation":[{"name":"Department of Animal Health, Instituto Nacional de Tecnologia Agropecuaria, Estacion Experimental Agropecuaria Marcos Juarez, Marcos Juarez, Cordoba, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5308","published-online":{"date-parts":[[2019,3,21]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Pijoan, C., Morrison, R. and Hilley, H. (1983) Serotyping of Pasteurella multocida isolated from swine lungs collected at slaughter. J. Clin. Microbiol., 17(6): 1074-1076.","DOI":"10.1128\/JCM.17.6.1074-1076.1983"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Opriessnig, T., Gim\u00e9nez-Lirola, L.G. and Halbur, P.G. (2011) Polymicrobial respiratory disease in pigs. Anim. Health Res. Rev., 12(2): 133-148.","DOI":"10.1017\/s1466252311000120"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Fuller, T.E., Kennedy, M.J. and Lowery, D.E. (2000) Identification of Pasteurella multocida virulence genes in a septicemic mouse model using signature-tagged mutagenesis. Microb. Pathog., 29(1): 25-38.","DOI":"10.1006\/mpat.2000.0365"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Harper, M., Boyce, J.D. and Adler, B. (2006) Pasteurella multocida pathogenesis: 125 years after Pasteur. FEMS Microbiol. 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(1967) Pasteurellosis: Pasteurella multocida and Pasteurella hemolytica. Adv. Vet. Sci., 11(1): 321-379."},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Rimler, R.B. and Rhoades, K.R. (1987) Serogroup F, a new capsule serogroup of Pasteurella multocida. J. Clin. Microbiol., 25(4): 615-618.","DOI":"10.1128\/JCM.25.4.615-618.1987"},{"key":"ref12","unstructured":"Leotta, G.A., Vigo, G.B., Chinen, I., Prieto, M., Callejo, R. and Rivas, M. (2006) Identificaci\u00f3n, biotipificaci\u00f3n y caracterizaci\u00f3n de cepas de Pasteurella multocida aisladas en la Argentina. Rev. Argent. Microbiol., 38(3): 125-129."},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Ewers, C., Lubke-Becker, A., Bethe, A., Kiessling, S., Filter, M. and Wieler, L. H. (2006) Virulence genotype of Pasteurella multocida strains isolated from different hosts with various disease status. Vet. 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